Control of CNS cell-fate decisions by SHP-2 and its dysregulation in Noonan syndrome

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Control of CNS cell-fate decisions by SHP-2 and its dysregulation in Noonan syndrome is …
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scholarly articleQ13442814

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P356DOI10.1016/J.NEURON.2007.03.027
P932PMC publication ID1900070
P698PubMed publication ID17442246
P5875ResearchGate publication ID6386902

P50authorFreda D. MillerQ64014566
David R KaplanQ88924076
P2093author name stringBenjamin G Neel
Toshiyuki Araki
Olivia Furstoss
Richard Chan
Andrée S Gauthier
P2860cites workMutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndromeQ24291893
The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signalingQ28182148
SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130Q28211408
Stops along the RAS pathway in human genetic diseaseQ28300658
Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptorQ28505506
Cardiotrophin-like cytokine induces astrocyte differentiation of fetal neuroepithelial cells via activation of STAT3Q28586818
Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutationQ28594140
Neuronal survival depends on EGFR signaling in cortical but not midbrain astrocytesQ34411046
Protein-tyrosine phosphatase, nonreceptor type 11 mutation analysis and clinical assessment in 45 patients with Noonan syndrome.Q34549142
Acquiring signalling specificity from the cytokine receptor gp130.Q35617769
Timing is everything: making neurons versus glia in the developing cortexQ36811626
Noonan's syndrome with hydrocephalus, hindbrain herniation, and upper cervical intracord cystQ36881538
CCAAT/enhancer-binding protein phosphorylation biases cortical precursors to generate neurons rather than astrocytes in vivo.Q40350530
Noonan syndrome-associated SHP2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activationQ40587895
Noonan syndrome. An update and review for the primary pediatricianQ40655730
Diverse biochemical properties of Shp2 mutants. Implications for disease phenotypesQ42480603
Chiari (type 1) malformation and syringomyelia in a patient with Noonan's syndromeQ42723553
Evidence that embryonic neurons regulate the onset of cortical gliogenesis via cardiotrophin-1.Q46768207
The T alpha 1 alpha-tubulin promoter specifies gene expression as a function of neuronal growth and regeneration in transgenic miceQ48077235
Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways.Q48267353
An essential role for a MEK-C/EBP pathway during growth factor-regulated cortical neurogenesisQ48443396
A case of Noonan syndrome with cortical dysplasiaQ48589568
Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathwayQ48617330
Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.Q48829693
Psychological profile of children with Noonan syndrome.Q52058797
Genotypic and phenotypic characterization of Noonan syndrome: New data and review of the literatureQ57775046
[Cerebral defects in Noonan's syndrome (author's transl)]Q70660943
The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus developmentQ72553432
CD44 expression identifies astrocyte-restricted precursor cellsQ80974440
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectNoonan syndromeQ1543446
P304page(s)245-262
P577publication date2007-04-01
P1433published inNeuronQ3338676
P1476titleControl of CNS cell-fate decisions by SHP-2 and its dysregulation in Noonan syndrome
P478volume54

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