scholarly article | Q13442814 |
P50 | author | Freda D. Miller | Q64014566 |
David R Kaplan | Q88924076 | ||
P2093 | author name string | Benjamin G Neel | |
Toshiyuki Araki | |||
Olivia Furstoss | |||
Richard Chan | |||
Andrée S Gauthier | |||
P2860 | cites work | Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome | Q24291893 |
The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling | Q28182148 | ||
SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130 | Q28211408 | ||
Stops along the RAS pathway in human genetic disease | Q28300658 | ||
Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor | Q28505506 | ||
Cardiotrophin-like cytokine induces astrocyte differentiation of fetal neuroepithelial cells via activation of STAT3 | Q28586818 | ||
Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation | Q28594140 | ||
Neuronal survival depends on EGFR signaling in cortical but not midbrain astrocytes | Q34411046 | ||
Protein-tyrosine phosphatase, nonreceptor type 11 mutation analysis and clinical assessment in 45 patients with Noonan syndrome. | Q34549142 | ||
Acquiring signalling specificity from the cytokine receptor gp130. | Q35617769 | ||
Timing is everything: making neurons versus glia in the developing cortex | Q36811626 | ||
Noonan's syndrome with hydrocephalus, hindbrain herniation, and upper cervical intracord cyst | Q36881538 | ||
CCAAT/enhancer-binding protein phosphorylation biases cortical precursors to generate neurons rather than astrocytes in vivo. | Q40350530 | ||
Noonan syndrome-associated SHP2/PTPN11 mutants cause EGF-dependent prolonged GAB1 binding and sustained ERK2/MAPK1 activation | Q40587895 | ||
Noonan syndrome. An update and review for the primary pediatrician | Q40655730 | ||
Diverse biochemical properties of Shp2 mutants. Implications for disease phenotypes | Q42480603 | ||
Chiari (type 1) malformation and syringomyelia in a patient with Noonan's syndrome | Q42723553 | ||
Evidence that embryonic neurons regulate the onset of cortical gliogenesis via cardiotrophin-1. | Q46768207 | ||
The T alpha 1 alpha-tubulin promoter specifies gene expression as a function of neuronal growth and regeneration in transgenic mice | Q48077235 | ||
Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways. | Q48267353 | ||
An essential role for a MEK-C/EBP pathway during growth factor-regulated cortical neurogenesis | Q48443396 | ||
A case of Noonan syndrome with cortical dysplasia | Q48589568 | ||
Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway | Q48617330 | ||
Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. | Q48829693 | ||
Psychological profile of children with Noonan syndrome. | Q52058797 | ||
Genotypic and phenotypic characterization of Noonan syndrome: New data and review of the literature | Q57775046 | ||
[Cerebral defects in Noonan's syndrome (author's transl)] | Q70660943 | ||
The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early Xenopus development | Q72553432 | ||
CD44 expression identifies astrocyte-restricted precursor cells | Q80974440 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Noonan syndrome | Q1543446 |
P304 | page(s) | 245-262 | |
P577 | publication date | 2007-04-01 | |
P1433 | published in | Neuron | Q3338676 |
P1476 | title | Control of CNS cell-fate decisions by SHP-2 and its dysregulation in Noonan syndrome | |
P478 | volume | 54 |
Q28512503 | A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis |
Q36682196 | A cellular star atlas: using astrocytes from human pluripotent stem cells for disease studies |
Q38125933 | A star is born: new insights into the mechanism of astrogenesis |
Q33758337 | Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia |
Q48908105 | Analysis of extracellular signal-regulated kinase 2 function in neural stem/progenitor cells via nervous system-specific gene disruption |
Q35945056 | Astrocytes and disease: a neurodevelopmental perspective |
Q38659714 | Attention deficit hyperactivity disorder (ADHD) in phenotypically similar neurogenetic conditions: Turner syndrome and the RASopathies |
Q54611405 | CNS imaging is a key diagnostic tool in the evaluation of patients with CFC syndrome: two cases and literature review. |
Q49031975 | Caspr Controls the Temporal Specification of Neural Progenitor Cells through Notch Signaling in the Developing Mouse Cerebral Cortex |
Q38440392 | Cocaine promotes primary human astrocyte proliferation via JNK-dependent up-regulation of cyclin A2. |
Q51900106 | Coffin-Lowry syndrome: a role for RSK2 in mammalian neurogenesis. |
Q48444899 | Cognitive functioning of adults with Noonan syndrome: a case-control study |
Q33637565 | Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase |
Q48657990 | Costello syndrome H-Ras alleles regulate cortical development |
Q30629384 | Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function. |
Q36176643 | Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality |
Q35760763 | Dysregulation of astrocyte extracellular signaling in Costello syndrome |
Q50528056 | Endogenous microglia regulate development of embryonic cortical precursor cells. |
Q34923711 | Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells |
Q40697770 | Fat1 interacts with Fat4 to regulate neural tube closure, neural progenitor proliferation and apical constriction during mouse brain development |
Q44700299 | FoxP2 regulates neurogenesis during embryonic cortical development. |
Q52646137 | Gain-of-function mutations in the gene encoding the tyrosine phosphatase SHP2 induce hydrocephalus in a catalytically dependent manner. |
Q37272605 | Genomic analysis of the molecular neuropathology of tuberous sclerosis using a human stem cell model. |
Q37385200 | Genotype differences in cognitive functioning in Noonan syndrome |
Q33675115 | Homozygous ARHGEF2 mutation causes intellectual disability and midbrain-hindbrain malformation. |
Q24652281 | Identification of neuronal nuclei (NeuN) as Fox-3, a new member of the Fox-1 gene family of splicing factors |
Q40650977 | Increased Activity of Src Homology 2 Domain Containing Phosphotyrosine Phosphatase 2 (Shp2) Regulates Activity-dependent AMPA Receptor Trafficking |
Q28590088 | Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells |
Q24621710 | MAP'ing CNS development and cognition: an ERKsome process |
Q41647387 | MEK Is a Key Regulator of Gliogenesis in the Developing Brain. |
Q36473553 | Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome. |
Q34413336 | Mechanisms of astrocyte development and their contributions to neurodevelopmental disorders |
Q54974212 | Mek1Y130C mice recapitulate aspects of human cardio-facio-cutaneous syndrome. |
Q37372285 | Negative regulation of Stat3 by activating PTPN11 mutants contributes to the pathogenesis of Noonan syndrome and juvenile myelomonocytic leukemia |
Q93096512 | Neurodevelopmental Aspects of RASopathies |
Q42964992 | Neurons or glia? Can SHP2 know it all? |
Q52101515 | Noonan syndrome, PTPN11 mutations, and brain tumors. A clinical report and review of the literature. |
Q38861759 | Noonan syndrome-associated SHP2 mutation differentially modulates the expression of postsynaptic receptors according to developmental maturation. |
Q37488326 | Postnatal activation of TLR4 in astrocytes promotes excitatory synaptogenesis in hippocampal neurons. |
Q53135944 | RAS/ERK signaling controls proneural genetic programs in cortical development and gliomagenesis. |
Q38132066 | Receptor tyrosine kinase (RTK) signalling in the control of neural stem and progenitor cell (NSPC) development |
Q24309381 | Receptor tyrosine phosphatase PTPγ is a regulator of spinal cord neurogenesis |
Q43104640 | Regulation of rod photoreceptor differentiation by STAT3 is controlled by a tyrosine phosphatase. |
Q46152847 | Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development |
Q34687531 | Role of neurotrophins on postnatal neurogenesis in the thalamus: prenatal exposure to ethanol |
Q33941989 | SHP-2 promotes the maturation of oligodendrocyte precursor cells through Akt and ERK1/2 signaling in vitro |
Q42556882 | Shp2 acts downstream of SDF-1alpha/CXCR4 in guiding granule cell migration during cerebellar development |
Q30399984 | Shp2 in forebrain neurons regulates synaptic plasticity, locomotion, and memory formation in mice |
Q34433715 | Shp2 suppresses PyMT-induced transformation in mouse fibroblasts by inhibiting Stat3 activity |
Q28506451 | Shp2-dependent ERK signaling is essential for induction of Bergmann glia and foliation of the cerebellum |
Q38711645 | Snail coordinately regulates downstream pathways to control multiple aspects of mammalian neural precursor development |
Q33573588 | Spred1, a negative regulator of Ras-MAPK-ERK, is enriched in CNS germinal zones, dampens NSC proliferation, and maintains ventricular zone structure |
Q47095740 | Structure and function of the contactin-associated protein family in myelinated axons and their relationship with nerve diseases. |
Q33754710 | Temporal requirement of the protein tyrosine phosphatase Shp2 in establishing the neuronal fate in early retinal development |
Q47926946 | The Molecular Pathway Regulating Bergmann Glia and Folia Generation in the Cerebellum |
Q64095083 | The Noonan Syndrome-linked Raf1L613V mutation drives increased glial number in the mouse cortex and enhanced learning |
Q33682478 | The RNA-binding protein MARF1 promotes cortical neurogenesis through its RNase activity domain |
Q34066270 | The Snail transcription factor regulates the numbers of neural precursor cells and newborn neurons throughout mammalian life |
Q35130067 | The contribution of natural selection to present-day susceptibility to chronic inflammatory and autoimmune disease |
Q34911307 | The language phenotype of children and adolescents with Noonan syndrome |
Q37543950 | The miR-17/106-p38 axis is a key regulator of the neurogenic-to-gliogenic transition in developing neural stem/progenitor cells |
Q37617410 | The protein tyrosine phosphatase Shp2 is required for the generation of oligodendrocyte progenitor cells and myelination in the mouse telencephalon |
Q37732956 | The tyrosine phosphatase Shp2 in development and cancer |
Q36225479 | Thyroid hormone promotes neuronal differentiation of embryonic neural stem cells by inhibiting STAT3 signaling through TRα1 |
Q37290726 | Top-down or bottom-up: Contrasting perspectives on psychiatric diagnoses |
Q28247569 | Tyrosine phosphatase SHP2 regulates the expression of acyl-CoA synthetase ACSL4 |
Q34007299 | Tyrosine phosphatases Shp1 and Shp2 have unique and opposing roles in oligodendrocyte development |
Q42454035 | p63 antagonizes p53 to promote the survival of embryonic neural precursor cells |