Hsp70 Knockdown by siRNA Decreased Collagen Production in Keloid Fibroblasts.

scientific article

Hsp70 Knockdown by siRNA Decreased Collagen Production in Keloid Fibroblasts. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3349/YMJ.2015.56.6.1619
P932PMC publication ID4630051
P698PubMed publication ID26446645
P5875ResearchGate publication ID283245892

P50authorJung U ShinQ60660182
P2093author name stringJu Hee Lee
Inhee Jung
Won Jai Lee
Thanh-Nga Tran
P2860cites workA hitchhiker's guide to the human Hsp70 familyQ24597572
Tissue inhibitor of metalloproteinase-2 (TIMP-2) binds to the catalytic domain of the cell surface receptor, membrane type 1-matrix metalloproteinase 1 (MT1-MMP)Q28258413
Suppression of expression of heat shock protein 70 by gefitinib and its contribution to pulmonary fibrosisQ28477887
The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic studyQ28619177
Protein folding in the cellQ29547792
New Therapies for the Management of KeloidsQ33193109
Prevention of UVB radiation-induced epidermal damage by expression of heat shock protein 70.Q33648551
Heat shock proteins modulate keloid formationQ34911441
Membrane type-matrix metalloproteinases (MT-MMP)Q35107597
Membrane type-1 matrix metalloproteinase and TIMP-2 in tumor angiogenesis.Q35114385
The anti-inflammatory effects of heat shock protein 72 involve inhibition of high-mobility-group box 1 release and proinflammatory function in macrophagesQ35990429
Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasionQ36298573
Hsp70 molecular chaperones: emerging roles in human disease and identification of small molecule modulatorsQ36536342
Role of keratinocyte-fibroblast cross-talk in development of hypertrophic scarQ36922420
Proteomic profiling reveals upregulated protein expression of hsp70 in keloids.Q37292100
A role for HSP70 in protecting against indomethacin-induced gastric lesionsQ37339375
Altered steady-state ratio of type I/III procollagen mRNAs correlates with selectively increased type I procollagen biosynthesis in cultured keloid fibroblastsQ37531506
Protective role of HSF1 and HSP70 against gastrointestinal diseasesQ37658800
The heat shock response: life on the verge of deathQ37802041
Heat shock protein 70 protects against bleomycin-induced pulmonary fibrosis in miceQ39698250
Fibroblasts from the growing margin of keloid scars produce higher levels of collagen I and III compared with intralesional and extralesional sites: clinical implications for lesional site-directed therapy.Q39836599
The molecular basis of keloid and hypertrophic scar formationQ40867502
Expression of integrin alpha(v)beta(3) correlates with activation of membrane-type matrix metalloproteinase-1 (MT1-MMP) and matrix metalloproteinase-2 (MMP-2) in human melanoma cells in vitro and in vivoQ40872675
Troglitazone suppresses transforming growth factor-beta1-induced collagen type I expression in keloid fibroblastsQ45364045
HSP70 confers protection against indomethacin-induced lesions of the small intestine.Q46003265
Analysis of differentially expressed genes in keloids and normal skin with cDNA microarrayQ47644991
Promoted activation of matrix metalloproteinase (MMP)-2 in keloid fibroblasts and increased expression of MMP-2 in collagen bundle regions: implications for mechanisms of keloid progressionQ47811329
Role of the heat-shock response in the life and death of proteins.Q47824004
Keloid-derived fibroblasts show increased secretion of factors involved in collagen turnover and depend on matrix metalloproteinase for migration.Q51375703
Conditioned medium from keloid keratinocyte/keloid fibroblast coculture induces contraction of fibroblast-populated collagen lattices.Q51497321
Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice.Q51873528
Effect of heat shock protein 47 on collagen synthesis of keloid in vivo.Q54326311
Genetic evidence for a protective role of heat shock factor 1 against irritant-induced gastric lesions.Q54565401
Modulation of collagen synthesis in keloid fibroblasts by silencing Smad2 with siRNA.Q54575597
Development of gene microarray in screening differently expressed genes in keloid and normal-control skin.Q54713611
Collagen gene expression in keloids: analysis of collagen metabolism and type I, III, IV, and V procollagen mRNAs in keloid tissue and keloid fibroblast culturesQ69225828
Activation of collagen gene expression in keloids: co-localization of type I and VI collagen and transforming growth factor-beta 1 mRNAQ70232613
Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosaQ71215708
Expression of membrane-type matrix metalloproteinase in human gastric carcinomasQ71887264
Upregulation of HSP47 and collagen type III in the dermal fibrotic disease, keloidQ73405631
Expression and activation of matrix metalloproteinase-2 (MMP-2) and its co-localization with membrane-type 1 matrix metalloproteinase (MT1-MMP) correlate with melanoma progressionQ73949261
Gelatinase activity in keloids and hypertrophic scarsQ78032742
Effect of heat shock protein 47 on collagen accumulation in keloid fibroblast cellsQ80398315
Genetic evidence for a protective role for heat shock factor 1 and heat shock protein 70 against colitisQ80446919
Protein profiling of keloidal scar tissueQ83620589
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P433issue6
P304page(s)1619-1626
P577publication date2015-11-01
P1433published inYonsei Medical JournalQ8055114
P1476titleHsp70 Knockdown by siRNA Decreased Collagen Production in Keloid Fibroblasts
P478volume56

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cites work (P2860)
Q92874811Antifibrotic Effects of High-Mobility Group Box 1 Protein Inhibitor (Glycyrrhizin) on Keloid Fibroblasts and Keloid Spheroids through Reduction of Autophagy and Induction of Apoptosis
Q64086326Caveolin-1 as a target in prevention and treatment of hypertrophic scarring
Q64947725Cell line-specific efficacy of thermoradiotherapy in human and canine cancer cells in vitro.
Q50067894Ginsenoside Rg3 inhibits keloid fibroblast proliferation, angiogenesis and collagen synthesis in vitro via the TGF‑β/Smad and ERK signaling pathways
Q90080306Heat Shock Proteins Are Essential Components in Transformation and Tumor Progression: Cancer Cell Intrinsic Pathways and Beyond
Q60955648In vitro analysis of the role of tumor necrosis factor‑stimulated gene‑6 in keloid
Q40623433Let-7c miRNA Inhibits the Proliferation and Migration of Heat-Denatured Dermal Fibroblasts Through Down-Regulating HSP70.
Q47237590MicroRNA-16 inhibits cell proliferation and migration by targeting heat shock protein 70 in heat-denatured dermal fibroblasts
Q52728381The inhibitory effects of 20(R)-ginsenoside Rg3 on the proliferation, angiogenesis, and collagen synthesis of hypertrophic scar derived fibroblasts in vitro.

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