Caveolin-1 as a target in prevention and treatment of hypertrophic scarring

scientific article published on 26 April 2019

Caveolin-1 as a target in prevention and treatment of hypertrophic scarring is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41536-019-0071-X
P932PMC publication ID6486604
P698PubMed publication ID31044089

P50authorPhilipp E. SchererQ60572448
P2093author name stringIlja L Kruglikov
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Expression of caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblastsQ33893828
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Nd:YAG Laser Treatment of Keloids and Hypertrophic Scars.Q34132927
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Sex-dependent expression of caveolin 1 in response to sex steroid hormones is closely associated with development of obesity in ratsQ35114438
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Caveolin-1 regulates osteoclastogenesis and bone metabolism in a sex-dependent mannerQ35173015
Methyl-β-cyclodextrin up-regulates collagen I expression in chronologically-aged skin via its anti-caveolin-1 activityQ35273298
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The sexual dimorphism associated with pulmonary hypertension corresponds to a fibrotic phenotypeQ35517586
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Caveolin-1, cellular senescence and age-related diseasesQ35626889
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Myofibroblasts in murine cutaneous fibrosis originate from adiponectin-positive intradermal progenitorsQ35755610
Heat Shock Protein 27 Plays a Pivotal Role in Myofibroblast Differentiation and in the Development of Bleomycin-Induced Pulmonary Fibrosis.Q35918416
Caveolin-1 deletion exacerbates cardiac interstitial fibrosis by promoting M2 macrophage activation in mice after myocardial infarction.Q35942679
Adiponectin at Physiologically Relevant Concentrations Enhances the Vasorelaxative Effect of Acetylcholine via Cav-1/AdipoR-1 SignalingQ35972970
Inhibition of basal and TGF β-induced fibroblast collagen synthesis by antineoplastic agents. Implications for wound healingQ35975961
Enhanced chemokine-receptor expression, function, and signaling in healthy African American and scleroderma-patient monocytes are regulated by caveolin-1.Q36001984
Prevalence of hypertrophic scar formation and its characteristics among the Chinese populationQ36181991
Hsp70 Knockdown by siRNA Decreased Collagen Production in Keloid Fibroblasts.Q36240167
Hypertrophic scar regression is linked to the occurrence of endothelial dysfunctionQ36363322
Dermal Adipocytes: From Irrelevance to Metabolic Targets?Q36421885
Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfideQ36638914
Universal physical responses to stretch in the living cellQ36737346
Exosome uptake depends on ERK1/2-heat shock protein 27 signaling and lipid Raft-mediated endocytosis negatively regulated by caveolin-1.Q36929092
Racial differences between blacks and whites with systemic sclerosisQ37129649
Heat shock proteins in diabetes and wound healingQ37411519
Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasisQ37586634
Downregulation of caveolin-1 increases the sensitivity of drug-resistant colorectal cancer HCT116 cells to 5-fluorouracilQ37593963
Interfacial Adipose Tissue in Systemic SclerosisQ37616390
Loss of caveolin-1 and adiponectin induces severe inflammatory lung injury following LPS challenge through excessive oxidative/nitrative stressQ37629301
The different functions and clinical significances of caveolin-1 in human adenocarcinoma and squamous cell carcinomaQ37652986
Deficient Adipogenesis of Scleroderma Patient and Healthy African American MonocytesQ37733744
Epidemiology and impact of scarring after burn injury: a systematic review of the literatureQ37964454
Caveolin-1 as a promoter of tumour spreading: when, how, where and why.Q38092213
TGF-β: the master regulator of fibrosisQ38816052
Caveolin-1 mediates chemoresistance in breast cancer stem cells via β-catenin/ABCG2 signaling pathwayQ38969421
Identification of biomarkers involved in differential profiling of hypertrophic and keloid scars versus normal skin.Q39112011
MMP-2 expression by fibroblasts is suppressed by the myofibroblast phenotypeQ39373799
Caveolin mediates rapid glucocorticoid effects and couples glucocorticoid action to the antiproliferative programQ40007726
Efficacy of IPL device combined with intralesional corticosteroid injection for the treatment of keloids and hypertrophic scars with regards to the recovery of skin barrier function: A pilot study.Q40266875
Mild Hyperthermia Induced by Gold Nanorod-Mediated Plasmonic Photothermal Therapy Enhances Transduction and Replication of Oncolytic Adenoviral Gene Delivery.Q40496634
Innate immunity. Dermal adipocytes protect against invasive Staphylococcus aureus skin infectionQ41566039
Innovative therapies in the treatment of keloids and hypertrophic scarsQ41813563
Hyperthermia and associated changes in membrane fluidity potentiate P2X7 activation to promote tumor cell deathQ42068171
Is There a Potential Therapeutic Role for Caveolin-1 in Fibrosis?Q42143749
The interaction of enolase-1 with caveolae-associated proteins regulates its subcellular localization.Q42224072
Release and activation of matrix metalloproteinase-9 during in vitro mechanical compression in hypertrophic scarsQ42519886
Decreased expression of caveolin 1 in patients with systemic sclerosis: crucial role in the pathogenesis of tissue fibrosisQ42600316
Dexamethasone induces caveolin-1 in vascular endothelial cells: implications for attenuated responses to VEGF.Q42712842
Caveolin internalization by heat shock or hyperosmotic shockQ42805046
N-[3,4-dimethoxycinnamoyl]-anthranilic acid (tranilast) inhibits transforming growth factor-beta relesase and reduces migration and invasiveness of human malignant glioma cellsQ42828380
Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalitiesQ43819817
Triamcinolone stimulates bFGF production and inhibits TGF-beta1 production by human dermal fibroblastsQ44099038
The effect of TLR4/7 on the TGF-β-induced Smad signal transduction pathway in human keloidQ44259971
Expression of the molecular chaperone Hsp70 in detergent-resistant microdomains correlates with its membrane delivery and releaseQ44394452
Hyaluronan regulates transforming growth factor-beta1 receptor compartmentalizationQ44844860
Overexpression of caveolin-1 inhibits endothelial cell proliferation by arresting the cell cycle at G0/G1 phaseQ44926435
Current concepts related to hypertrophic scarring in burn injuries.Q45985097
Transforming growth factor beta (TGF-beta) and dexamethasone have direct opposing effects on collagen metabolism in low passage human dermal fibroblasts in vitroQ46113389
Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and BeyondQ47138289
Caveolin-1-eNOS/Hsp70 interactions mediate rosuvastatin antifibrotic effects in neonatal obstructive nephropathy.Q47643553
Matrix metalloproteinases and tissue inhibitors of metalloproteinases in patients with different types of scars and keloidsQ47737288
Ultrasound induced strain cytoskeleton rearrangement: An experimental and simulation study.Q47865348
Effects and mechanisms of pirfenidone, prednisone and acetylcysteine on pulmonary fibrosis in rat idiopathic pulmonary fibrosis modelsQ48023126
Treatment of hypertrophic scars with intralesional botulinum toxin type A injections: a preliminary reportQ48027687
Caveolin-1 Expression Increases upon Maturation in Dendritic Cells and Promotes Their Migration to Lymph Nodes Thereby Favoring the Induction of CD8+ T Cell Responses.Q49691061
Reversal of maladaptive fibrosis and compromised ventricular function in the pressure overloaded heart by a caveolin-1 surrogate peptide.Q51174046
Caveolin-1 Mediates Low-Intensity Ultrasound-Induced Apoptosis via Downregulation of Signal Transducer and Activator of Transcription 3 Phosphorylation in Laryngeal Carcinoma Cells.Q51295442
Low-Intensity Pulsed Ultrasound Enhances Angiogenesis and Ameliorates Left Ventricular Dysfunction in a Mouse Model of Acute Myocardial Infarction.Q51370978
Expression of heat shock proteins after ultrasound exposure in HL-60 cells.Q51769621
Systemic depletion of macrophages in the subacute phase of wound healing reduces hypertrophic scar formation.Q52870062
Botulinum toxin type a inhibits connective tissue growth factor expression in fibroblasts derived from hypertrophic scar.Q53257180
The expression of Cyclin A and p21cip1 in fibroblast of hypertrophic scarQ53291565
Systemic sclerosis in 2016: Dermal white adipose tissue implicated in SSc pathogenesis.Q53762916
Transforming growth factor-beta protection of cancer cells against tumor necrosis factor cytotoxicity is counteracted by hyaluronidase (review).Q54112975
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)9
P577publication date2019-04-26
P1433published inNPG Regenerative MedicineQ50815323
P1476titleCaveolin-1 as a target in prevention and treatment of hypertrophic scarring
P478volume4

Reverse relations

cites work (P2860)
Q92254959Caveolin as a Universal Target in Dermatology
Q98463690The MMP14-caveolin axis and its potential relevance for lipoedema
Q92035115The importance of caveolins and caveolae to dermatology: Lessons from the caves and beyond

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