Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide

scientific article published on 30 March 2011

Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TAAP.2011.03.015
P932PMC publication ID3582383
P698PubMed publication ID21457723

P2093author name stringPatrick J Hayden
Jeffrey D Laskin
Debra L Laskin
Patrick J Sinko
Adrienne T Black
Diane E Heck
Donald R Gerecke
Robert P Casillas
P2860cites workAn inhibitor of p38 MAP kinase downregulates cytokine release induced by sulfur mustard exposure in human epidermal keratinocytesQ24299262
Lipid rafts and signal transductionQ28131735
Aquaporin 3 colocates with phospholipase d2 in caveolin-rich membrane microdomains and is downregulated upon keratinocyte differentiationQ28191507
Association of heat shock proteins and neuronal membrane components with lipid rafts from the rat brainQ28571921
The chaperone function of hsp70 is required for protection against stress-induced apoptosisQ28679271
Caveolin-1 expression by means of p38beta mitogen-activated protein kinase mediates the antiproliferative effect of carbon monoxideQ28771403
Molecular chaperones and the cytoskeletonQ30427785
Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless miceQ33570853
Oxidants and antioxidants in sulfur mustard-induced injuryQ33621786
Mechanisms mediating the vesicant actions of sulfur mustard after cutaneous exposureQ33645035
Prevention of UVB radiation-induced epidermal damage by expression of heat shock protein 70.Q33648551
Involvement of Caveolin-1 in repair of DNA damage through both homologous recombination and non-homologous end joiningQ33654095
A detergent-free method for purifying caveolae membrane from tissue culture cellsQ33818572
Chaperones in cell cycle regulation and mitogenic signal transduction: a reviewQ34095732
Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfideQ34378347
Heat shock proteins in the photobiology of human skinQ34421860
Expression of heat shock proteins in mouse skin during wound healingQ34475457
Microtubules and actin microfilaments regulate lipid raft/caveolae localization of adenylyl cyclase signaling componentsQ34544258
Chaperones in control of protein disaggregationQ34740513
Multiple functions of caveolin-1.Q34790966
Molecular toxicology of sulfur mustard-induced cutaneous inflammation and blisteringQ34995354
p38MAPK inhibition prevents disease in pemphigus vulgaris miceQ35036492
Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formationQ35791457
Role of caveolae and caveolins in health and diseaseQ35895205
Heat shock protein 70 regulates cellular redox status by modulating glutathione-related enzyme activitiesQ35981152
Hsp27 consolidates intracellular redox homeostasis by upholding glutathione in its reduced form and by decreasing iron intracellular levels.Q36038180
Role of MAP kinases in regulating expression of antioxidants and inflammatory mediators in mouse keratinocytes following exposure to the half mustard, 2-chloroethyl ethyl sulfide.Q36638919
Molecular chaperones: multiple functions, pathologies, and potential applicationsQ36664175
Tether and trap: regulation of membrane-raft dynamics by actin-binding proteins.Q36975737
Autoantibodies in the autoimmune disease pemphigus foliaceus induce blistering via p38 mitogen-activated protein kinase-dependent signaling in the skinQ37061072
Induction of heat shock proteins for protection against oxidative stressQ37402933
Heat shock proteins in diabetes and wound healingQ37411519
Identification of filamin as a novel ligand for caveolin-1: evidence for the organization of caveolin-1-associated membrane domains by the actin cytoskeletonQ38478215
The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation.Q39740388
Direct binding of sulfur mustard and chloroethyl ethyl sulphide to human cell membrane-associated proteins; implications for sulfur mustard pathologyQ39764486
Proteomics of MUC1-containing lipid rafts from plasma membranes and exosomes of human breast carcinoma cells MCF-7.Q39856870
Heat stress upregulates chaperone heat shock protein 70 and antioxidant manganese superoxide dismutase through reactive oxygen species (ROS), p38MAPK, and Akt.Q39871976
Hsp70 translocates into the plasma membrane after stress and is released into the extracellular environment in a membrane-associated form that activates macrophages.Q40005411
Oxidative stress induces premature senescence by stimulating caveolin-1 gene transcription through p38 mitogen-activated protein kinase/Sp1-mediated activation of two GC-rich promoter elementsQ40208065
Selective stimulation of Hsp27 and alphaB-crystallin but not Hsp70 expression by p38 MAP kinase activation.Q40425069
Exosome-dependent trafficking of HSP70: a novel secretory pathway for cellular stress proteinsQ40436107
Heat shock proteins and molecular chaperones: implications for adaptive responses in the skinQ40500635
Modulation of actin microfilament dynamics and fluid phase pinocytosis by phosphorylation of heat shock protein 27.Q41514183
Expression of HSP70 in healing wounds of diabetic and nondiabetic miceQ41685880
Treatment of keratin intermediate filaments with sulfur mustard analogsQ42085351
Caveolin expression and localization in human keratinocytes suggest a role in lamellar granule biogenesisQ42438562
Basolateral membrane-associated 27-kDa heat shock protein and microfilament polymerizationQ42445230
Expression of the 27-kDa heat shock protein in human epidermis and in epidermal neoplasms: an immunohistological studyQ42478137
Immunolocalization of low-molecular-weight stress protein HSP 27 in normal skin and common cutaneous lesionsQ42487272
Caveolin-1 and Hsp70 interaction in microdissected proximal tubules from spontaneously hypertensive rats as an effect of LosartanQ43218063
The small heat-shock protein Hsp27 undergoes ERK-dependent phosphorylation and redistribution to the cytoskeleton in response to dual leucine zipper-bearing kinase expressionQ43292767
Human keratinocytes respond to osmotic stress by p38 map kinase regulated induction of HSP70 and HSP27.Q43800866
Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activationQ44015062
Expression of the molecular chaperone Hsp70 in detergent-resistant microdomains correlates with its membrane delivery and releaseQ44394452
Sulfur mustard induces the formation of keratin aggregates in human epidermal keratinocytesQ44673574
In vivo ozone exposure induces antioxidant/stress-related responses in murine lung and skinQ44774499
The "caveolae brake hypothesis" and the epidermal barrierQ46249982
Role of NF-kappaB/RelA and MAPK pathways in keratinocytes in response to sulfur mustardQ46804682
Heat shock protein-70 mediates the cytoprotective effect of carbon monoxide: involvement of p38 beta MAPK and heat shock factor-1.Q53663061
Impaired repair ability of hsp70.1 KO mouse after UVB irradiation.Q53673745
Glucocorticoid treatment induces expression of small heat shock proteins in human satellite cell populations: consequences for a desmin-related myopathy involving the R120G alpha B-crystallin mutationQ74180058
Subcorneal colocalization of the small heat shock protein, hsp27, with keratins and proteins of the cornified cell envelopeQ74418261
Induction of p38MAPK and HSP27 phosphorylation in pemphigus patient skinQ81422121
Desmosome signaling. Inhibition of p38MAPK prevents pemphigus vulgaris IgG-induced cytoskeleton reorganizationQ81666502
HSP72 depletion suppresses gammaH2AX activation by genotoxic stresses via p53/p21 signalingQ82452820
In vivo delivery of heat shock protein 70 accelerates wound healing by up-regulating macrophage-mediated phagocytosisQ83185520
P433issue2
P304page(s)112-120
P577publication date2011-03-30
P1433published inToxicology and Applied PharmacologyQ2446974
P1476titleRegulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide
P478volume253

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cites work (P2860)
Q52618282Absence of caveolin-1 alters heat shock protein expression in spontaneous mammary tumors driven by Her-2/neu expression.
Q89955777Antioxidant/stress response in mouse epidermis following exposure to nitrogen mustard
Q36951486Autoimmunoreactive IgGs against cardiac lipid raft-associated proteins in patients with postural orthostatic tachycardia syndrome.
Q64086326Caveolin-1 as a target in prevention and treatment of hypertrophic scarring
Q42811565GRP75 upregulates clathrin-independent endocytosis through actin cytoskeleton reorganization mediated by the concurrent activation of Cdc42 and RhoA.
Q37690877Localisation Microscopy of Breast Epithelial ErbB-2 Receptors and Gap Junctions: Trafficking after γ-Irradiation, Neuregulin-1β, and Trastuzumab Application.
Q35343637Regulation of keratinocyte expression of stress proteins and antioxidants by the electrophilic nitrofatty acids 9- and 10-nitrooleic acid
Q95643670Skin remodeling and wound healing in the Gottingen minipig following exposure to sulfur mustard
Q46856232The effect of manganese-induced cytotoxicity on mRNA expressions of HSP27, HSP40, HSP60, HSP70 and HSP90 in chicken spleen lymphocytes in vitro.
Q58779263Transient Receptor Potential Channel A1 (TRPA1) Regulates Sulfur Mustard-Induced Expression of Heat Shock 70 kDa Protein 6 () In Vitro

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