| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Ivan Topisirovic | |
| Katherine L B Borden | |||
| Laurent Volpon | |||
| Ling Shao | |||
| Clifford E Soll | |||
| Alex Kentsis | |||
| Biljana Culjkovic | |||
| P2860 | cites work | PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA. | Q24291551 |
| Control of biochemical reactions through supramolecular RING domain self-assembly | Q24539123 | ||
| Poly(A)-binding protein interaction with elF4G stimulates picornavirus IRES-dependent translation | Q24540068 | ||
| Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins | Q27639133 | ||
| Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein | Q27743943 | ||
| Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap | Q33582891 | ||
| Cap-Poly(A) synergy in mammalian cell-free extracts. Investigation of the requirements for poly(A)-mediated stimulation of translation initiation | Q33912083 | ||
| The antiviral drug ribavirin does not mimic the 7-methylguanosine moiety of the mRNA cap structure in vitro | Q34366602 | ||
| Pleiotropic mechanisms of ribavirin antiviral activities | Q35012758 | ||
| eIF-4E expression and its role in malignancies and metastases. | Q35750118 | ||
| Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E. | Q37729445 | ||
| Tethered-function analysis reveals that elF4E can recruit ribosomes independent of its binding to the cap structure. | Q41838027 | ||
| Picornavirus IRESes and the poly(A) tail jointly promote cap-independent translation in a mammalian cell-free system | Q41943778 | ||
| Ribavirin is not a functional mimic of the 7-methyl guanosine mRNA cap. | Q42033076 | ||
| The interaction of eIF4E with 4E-BP1 is an induced fit to a completely disordered protein | Q42123533 | ||
| The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E. | Q43749953 | ||
| A solubility-enhancement tag (SET) for NMR studies of poorly behaving proteins. | Q52059754 | ||
| A spectroscopic study of the binding of m7GTP and m7GpppG to human protein synthesis initiation factor 4E | Q69415354 | ||
| A reevaluation of the cap-binding protein, eIF4E, as a rate-limiting factor for initiation of translation in reticulocyte lysate | Q71058730 | ||
| An efficient system for cap- and poly(A)-dependent translation in vitro | Q75447309 | ||
| Internal and overall motions of the translation factor eIF4E: cap binding and insertion in a CHAPS detergent micelle | Q77210983 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | ribavirin | Q421862 |
| P304 | page(s) | 1762-1766 | |
| P577 | publication date | 2005-10-26 | |
| P1433 | published in | RNA | Q7277164 |
| P1476 | title | Further evidence that ribavirin interacts with eIF4E | |
| P478 | volume | 11 |
| Q43087319 | A phase I trial of ribavirin and low-dose cytarabine for the treatment of relapsed and refractory acute myeloid leukemia with elevated eIF4E. |
| Q38098701 | Aiding and abetting cancer: mRNA export and the nuclear pore |
| Q39869989 | Anti-tumor effect of ribavirin in combination with interferon-α on renal cell carcinoma cell lines in vitro |
| Q38732613 | Autophagy suppression sensitizes glioma cells to IMP dehydrogenase inhibition-induced apoptotic death. |
| Q38001940 | Cap-dependent translation initiation factor eIF4E: an emerging anticancer drug target |
| Q40872139 | Conformational changes induced in the eukaryotic translation initiation factor eIF4E by a clinically relevant inhibitor, ribavirin triphosphate |
| Q38227377 | Eukaryotic translation initiation factor 4E as a novel therapeutic target in hematological malignancies and beyond |
| Q36904927 | Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E. |
| Q58109386 | Improving the Breadth of the Host's Immune Response to Lassa Virus |
| Q47584869 | Inhibition of eIF4E cooperates with chemotherapy and immunotherapy in renal cell carcinoma. |
| Q33648488 | Initiation factor eIF2-independent mode of c-Src mRNA translation occurs via an internal ribosome entry site |
| Q28755220 | Pondering the puzzle of PML (promyelocytic leukemia) nuclear bodies: can we fit the pieces together using an RNA regulon? |
| Q35758763 | Ribavirin Inhibits the Activity of mTOR/eIF4E, ERK/Mnk1/eIF4E Signaling Pathway and Synergizes with Tyrosine Kinase Inhibitor Imatinib to Impair Bcr-Abl Mediated Proliferation and Apoptosis in Ph+ Leukemia |
| Q52682258 | Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors. |
| Q24594939 | Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond? |
| Q47720139 | Ribavirin augments doxorubicin's efficacy in human hepatocellular carcinoma through inhibiting doxorubicin-induced eIF4E activation. |
| Q39950178 | Ribavirin targets eIF4E dependent Akt survival signaling |
| Q37865381 | Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy. |
| Q93382193 | Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia |
| Q34130816 | Targeting eukaryotic translation initiation factor 4E (eIF4E) in cancer |
| Q39172901 | Targeting of protein translation as a new treatment paradigm for prostate cancer |
| Q34173253 | Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway |
| Q38699320 | Targeting translation: eIF4E as an emerging anticancer drug target |
| Q41036251 | The ABC7 regimen: a new approach to metastatic breast cancer using seven common drugs to inhibit epithelial-to-mesenchymal transition and augment capecitabine efficacy |
| Q43089875 | The Development of Novel Therapies for the Treatment of Acute Myeloid Leukemia (AML). |
| Q38634592 | The Eukaryotic Translation Initiation Factor 4E (eIF4E) as a Therapeutic Target for Cancer |
| Q59130174 | The Impact of Post-transcriptional Control: Better Living Through RNA Regulons |
| Q37848652 | The biological and therapeutic relevance of mRNA translation in cancer |
| Q36527188 | The eIF4E RNA regulon promotes the Akt signaling pathway |
| Q38289051 | The eukaryotic translation initiation factor eIF4E in the nucleus: taking the road less traveled |
| Q40616450 | The eukaryotic translation initiation factor eIF4E is a direct transcriptional target of NF-κB and is aberrantly regulated in acute myeloid leukemia |
| Q39549442 | The eukaryotic translation initiation factor eIF4E wears a "cap" for many occasions |
| Q39295500 | The oncogene eIF4E reprograms the nuclear pore complex to promote mRNA export and oncogenic transformation |
| Q36842143 | The oncogene eIF4E: using biochemical insights to target cancer |
| Q37837732 | Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways. |
| Q37801949 | Translational control gone awry: a new mechanism of tumorigenesis and novel targets of cancer treatments |
| Q24338136 | Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1 |
| Q40429761 | Use of an anti-viral drug, Ribavirin, as an anti-glioblastoma therapeutic. |
| Q34715457 | When will resistance be futile? |
| Q35552009 | eIF4E and eIF4GI have distinct and differential imprints on multiple myeloma's proteome and signaling |
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