Sexually dimorphic effect of aging on skeletal muscle protein synthesis

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Sexually dimorphic effect of aging on skeletal muscle protein synthesis is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1047021196
P356DOI10.1186/2042-6410-3-11
P932PMC publication ID3467175
P698PubMed publication ID22620287
P5875ResearchGate publication ID225057240

P50authorGordon I SmithQ42849999
Angela M HallQ57320141
Bettina MittendorferQ86873152
Dominic N. ReedsQ124619423
P2093author name stringBrian N Finck
Kari T Chambers
P2860cites workOrganization of the human myostatin gene and expression in healthy men and HIV-infected men with muscle wastingQ22008491
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Resistance exercise increases leg muscle protein synthesis and mTOR signalling independent of sexQ33895553
Resistance exercise acutely increases MHC and mixed muscle protein synthesis rates in 78-84 and 23-32 yr oldsQ33897075
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Age-related differences in skeletal muscle protein synthesis: relation to markers of immune activationQ34378959
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The response of muscle protein anabolism to combined hyperaminoacidemia and glucose-induced hyperinsulinemia is impaired in the elderly.Q35335129
Control of the size of the human muscle massQ35672556
Signaling pathways weigh in on decisions to make or break skeletal muscleQ35802216
Testosterone increases the muscle protein synthesis rate but does not affect very-low-density lipoprotein metabolism in obese premenopausal women.Q35849393
Effect of food form on postprandial plasma amino acid concentrations in older adultsQ36010513
Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitorsQ36670010
Increased secretion and expression of myostatin in skeletal muscle from extremely obese women.Q37023094
Higher muscle protein synthesis in women than men across the lifespan, and failure of androgen administration to amend age-related decrements.Q37072420
Stimulation of skeletal muscle myofibrillar protein synthesis, p70 S6 kinase phosphorylation, and ribosomal protein S6 phosphorylation by inhibition of myostatin in mature miceQ37138720
Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesisQ37233128
Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with agingQ37273785
No major sex differences in muscle protein synthesis rates in the postabsorptive state and during hyperinsulinemia-hyperaminoacidemia in middle-aged adults.Q37391984
Isolation of aminoacyl-tRNA and its labeling with stable-isotope tracers: Use in studies of human tissue protein synthesisQ37543199
PI3 kinase regulation of skeletal muscle hypertrophy and atrophyQ37769163
Testosterone administration to elderly men increases skeletal muscle strength and protein synthesisQ39369061
Age-related differences in the dose-response relationship of muscle protein synthesis to resistance exercise in young and old men.Q42444632
Human muscle protein synthesis is modulated by extracellular, not intramuscular amino acid availability: a dose-response studyQ42445886
Protein synthesis rates in human muscles: neither anatomical location nor fibre-type composition are major determinantsQ42472104
Effects of acute creatine monohydrate supplementation on leucine kinetics and mixed-muscle protein synthesisQ43710029
Gender differences in lipid and glucose kinetics during short-term fastingQ43794404
Inverse regulation of protein turnover and amino acid transport in skeletal muscle of hypercatabolic patientsQ44055226
Serum amino acid concentrations in aging men and womenQ44455198
Body composition changes in stable-weight elderly subjects: the effect of sex.Q44684190
Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men.Q45933584
Down-regulation of Akt/mammalian target of rapamycin signaling pathway in response to myostatin overexpression in skeletal muscleQ46359311
No effect of menstrual cycle on myofibrillar and connective tissue protein synthesis in contracting skeletal muscleQ46677543
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Longitudinal changes in body composition in older men and women: role of body weight change and physical activityQ47180886
Weight stability masks sarcopenia in elderly men and womenQ47233662
Effects of aging on in vivo synthesis of skeletal muscle myosin heavy-chain and sarcoplasmic protein in humans.Q50926260
Protein anabolic responses to a fed steady state in healthy aging.Q51376114
Carbohydrate, fat, and protein metabolism in muscle and in the whole body after mixed meal ingestionQ52563880
Resting and load-induced levels of myogenic gene transcripts differ between older adults with demonstrable sarcopenia and young men and women.Q53849584
Muscle full effect after oral protein: time-dependent concordance and discordance between human muscle protein synthesis and mTORC1 signalingQ54649818
Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia.Q55042094
Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men.Q55051183
Effect of testosterone on muscle mass and muscle protein synthesis.Q55060315
Last Word on Viewpoint: The curious case of anabolic resistance: old wives' tales or new fables?Q57580354
Relation between whole-body and regional measures of human skeletal muscleQ57717642
Inflammatory Markers and Loss of Muscle Mass (Sarcopenia) and StrengthQ60298077
Effect of testosterone on muscle protein synthesis in myotonic dystrophyQ68980167
Adult lean body mass declines with age: some longitudinal observationsQ71543853
Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadismQ71857797
Measurement of very low stable isotope enrichments by gas chromatography/mass spectrometry: application to measurement of muscle protein synthesisQ73589672
Different limit to the body's ability of increasing fat-free massQ74509907
Insulin-like growth factor-1 and myostatin mRNA expression in muscle: comparison between 62-77 and 21-31 yr old menQ74603310
Testosterone injection stimulates net protein synthesis but not tissue amino acid transportQ77551195
Measurement of human mixed muscle protein fractional synthesis rate depends on the choice of amino acid tracerQ80400135
Impaired anabolic response of muscle protein synthesis is associated with S6K1 dysregulation in elderly humansQ80471118
Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acidsQ81464932
P433issue1
P921main subjectsexual dimorphismQ181497
P304page(s)11
P577publication date2012-05-23
P1433published inBiology of Sex DifferencesQ27723474
P1476titleSexually dimorphic effect of aging on skeletal muscle protein synthesis
P478volume3

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cites work (P2860)
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Q91938519Influence of Oral Contraceptive Use on Adaptations to Resistance Training
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Q90293361Nutritional Strategies to Combat Type 2 Diabetes in Aging Adults: The Importance of Protein
Q35773010Prolonged Adaptation to a Low or High Protein Diet Does Not Modulate Basal Muscle Protein Synthesis Rates - A Substudy
Q34790537Quantity of dietary protein intake, but not pattern of intake, affects net protein balance primarily through differences in protein synthesis in older adults
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Q36698656Sexual dimorphism in skeletal muscle protein turnover
Q28262423Skeletal muscle homeostasis and plasticity in youth and ageing: impact of nutrition and exercise
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Q24186948Treatment for inclusion body myositis

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