review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Pal Pacher | Q30347235 |
Csaba Szabó | Q106704479 | ||
P2860 | cites work | Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies | Q24656109 |
Biochemistry and molecular cell biology of diabetic complications | Q28131781 | ||
Prevention of the complications of diabetes | Q28195480 | ||
Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress | Q29615436 | ||
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage | Q29616101 | ||
Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes | Q30769310 | ||
Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolaemia | Q30813656 | ||
Lipid peroxidation, protein thiol oxidation and DNA damage in hydrogen peroxide-induced injury to endothelial cells: role of activation of poly(ADP-ribose)polymerase | Q67990314 | ||
Nicotinamide and 3-aminobenzamide inhibit recombinant human interferon-gamma-induced HLA-DR antigen expression, but not HLA-A, B, C antigen expression, on cultured human thyroid cells | Q68054486 | ||
Reactive oxygen injury to cultured pulmonary artery endothelial cells: mediation by poly(ADP-ribose) polymerase activation causing NAD depletion and altered energy balance | Q68255326 | ||
Differential effects of hyperoxia and hydrogen peroxide on DNA damage, polyadenosine diphosphate-ribose polymerase activity, and nicotinamide adenine dinucleotide and adenosine triphosphate contents in cultured endothelial cells and fibroblasts | Q69208927 | ||
Mechanisms of endothelial cell ATP depletion after oxidant injury | Q69294343 | ||
Homocysteine mediated endothelial cell toxicity and its amelioration | Q71434899 | ||
Inhibition of the induction of collagenase by interleukin-1 beta in cultured rabbit synovial fibroblasts after treatment with the poly(ADP-ribose)-polymerase inhibitor 3-aminobenzamide | Q71602350 | ||
Menadione-induced oxidative stress in bovine heart microvascular endothelial cells | Q71626019 | ||
Acute pneumocyte injury, poly(ADP-ribose) polymerase activity, and pyridine nucleotide levels after in vitro exposure of murine lung slices to cyclophosphamide | Q72857176 | ||
Inhibitors of poly(adenosine diphosphate ribose) polymerase induce sister chromatid exchanges | Q72885731 | ||
Vascular superoxide production by NAD(P)H oxidase: association with endothelial dysfunction and clinical risk factors | Q73783792 | ||
Assessment of DNA strand breakage by comet assay in diabetic patients and the role of antioxidant supplementation | Q73849830 | ||
[Vascular endothelium: a target organ for diabetes mellitus] | Q74201668 | ||
Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion | Q77089411 | ||
Hydrogen peroxide decreases pHi in human aortic endothelial cells by inhibiting Na+/H+ exchange | Q77315019 | ||
Role of peroxynitrite and poly (ADP-ribosyl) synthetase activation in cardiovascular derangement induced by zymosan in the rat | Q77332053 | ||
The role of poly(ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes | Q77550010 | ||
Endothelial dysfunction in diabetes mellitus | Q77778745 | ||
The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases | Q30824712 | ||
Diabetes and endothelial dysfunction: a clinical perspective | Q31835799 | ||
Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice | Q33891214 | ||
Role of poly(ADP-ribose) polymerase in rapid intracellular acidification induced by alkylating DNA damage | Q33897296 | ||
Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death | Q33948501 | ||
Endothelial dysfunction in diabetes. | Q33959485 | ||
Endothelial dysfunction in hypercholesterolemia: mechanisms, pathophysiological importance, and therapeutic interventions | Q34113182 | ||
Elevated levels of oxidative DNA damage and DNA repair enzymes in human atherosclerotic plaques | Q34145177 | ||
Importance of poly(ADP-ribose) glycohydrolase in the control of poly(ADP-ribose) metabolism. | Q34312540 | ||
Diabetic endothelial dysfunction: role of reactive oxygen and nitrogen species production and poly(ADP-ribose) polymerase activation. | Q34340925 | ||
Role of poly(ADP-ribose) formation in DNA repair | Q34359946 | ||
Oxidative stress and diabetic vascular complications | Q34391178 | ||
Angiotensin II-mediated endothelial dysfunction: role of poly(ADP-ribose) polymerase activation | Q34521265 | ||
Tetrahydrobiopterin biosynthesis, utilization and pharmacological effects. | Q34633011 | ||
The therapeutic potential of poly(ADP-ribose) polymerase inhibitors | Q34838585 | ||
Endothelial dysfunction in aging animals: the role of poly(ADP-ribose) polymerase activation | Q35044253 | ||
Cellular basis of endothelial dysfunction in small mesenteric arteries from spontaneously diabetic (db/db -/-) mice: role of decreased tetrahydrobiopterin bioavailability | Q35044339 | ||
Poly(ADP-ribose) polymerase inhibitors | Q35060963 | ||
Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes | Q35065308 | ||
Etiology and treatment of erectile failure in diabetes mellitus | Q35087516 | ||
Preventing microvascular diabetic complications in children and adolescents: looking beyond glycaemic control | Q35095210 | ||
New Insights on Oxidative Stress and Diabetic Complications May Lead to a “Causal” Antioxidant Therapy | Q35115544 | ||
Heart failure: the frequent, forgotten, and often fatal complication of diabetes | Q35185828 | ||
Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymerase | Q35271750 | ||
Treatment of diabetic nephropathy with angiotensin II receptor antagonist | Q35571967 | ||
Update on the pathogenesis of diabetic neuropathy | Q35581275 | ||
Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle | Q35960752 | ||
Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells | Q36001244 | ||
Diabetes, microvascular complications, and cardiovascular complications: what is it about glucose? | Q36001352 | ||
Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase | Q36011589 | ||
Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalyst | Q36087920 | ||
Nitrosative stress and pharmacological modulation of heart failure | Q36145124 | ||
Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors | Q36253833 | ||
Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure | Q36297600 | ||
Glucose and diabetic vascular disease. | Q36379991 | ||
Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells | Q36654891 | ||
Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite | Q37370840 | ||
Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications | Q37373683 | ||
Protection against hemorrhagic shock in mice genetically deficient in poly(ADP-ribose)polymerase | Q37429030 | ||
DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite | Q37700756 | ||
Endothelial dysfunction and peroxynitrite formation are early events in angiotensin-induced cardiovascular disorders. | Q39527979 | ||
Evaluation of orally active poly(ADP-ribose) polymerase inhibitor in streptozotocin-diabetic rat model of early peripheral neuropathy | Q39691668 | ||
Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst | Q39703468 | ||
Structure and function of poly(ADP-ribose) polymerase | Q40616439 | ||
Molecular and biochemical features of poly (ADP-ribose) metabolism | Q40776253 | ||
Increased single strand breaks in DNA of lymphocytes from diabetic subjects | Q40921015 | ||
Regulation of components of the inflammatory response by 5-iodo-6-amino-1,2-benzopyrone, an inhibitor of poly(ADP-ribose) synthetase and pleiotropic modifier of cellular signal pathways. | Q41105787 | ||
Protective effect of nicotinamide against nephropathy in diabetic rats | Q41352682 | ||
Cellular responses to DNA damage in the absence of Poly(ADP-ribose) polymerase | Q41735913 | ||
Effects of angiotensin II on vascular endothelial cells: formation of receptor-mediated reactive nitrogen species | Q42438952 | ||
Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation | Q42497877 | ||
Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion | Q43173946 | ||
Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase | Q43764637 | ||
Effects of insulin and antioxidant on plasma 8-hydroxyguanine and tissue 8-hydroxydeoxyguanosine in streptozotocin-induced diabetic rats | Q43808969 | ||
Poly(ADP-Ribose) polymerase inhibition reduces reperfusion injury after heart transplantation | Q43851360 | ||
Inhibition of protein kinase Cbeta prevents impaired endothelium-dependent vasodilation caused by hyperglycemia in humans | Q43851364 | ||
Activation of poly(ADP-ribose) polymerase contributes to development of doxorubicin-induced heart failure | Q43893501 | ||
Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase | Q43952389 | ||
Resistance to acute septic peritonitis in poly(ADP-ribose) polymerase-1-deficient mice | Q43960156 | ||
Novel phenanthridinone inhibitors of poly (adenosine 5'-diphosphate-ribose) synthetase: potent cytoprotective and antishock agents | Q43990309 | ||
Activation of poly(ADP-ribose) polymerase contributes to the endothelial dysfunction associated with hypertension and aging. | Q43994462 | ||
Hypoxia-reoxygenation: a potent inducer of apoptotic changes in the human placenta and possible etiological factor in preeclampsia. | Q44044678 | ||
Poly(ADP-ribose) polymerase inhibition prevents both apoptotic-like delayed neuronal death and necrosis after H(2)O(2) injury | Q44046046 | ||
Pharmacologic inhibition of poly(adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure | Q44133546 | ||
Poly(ADP-Ribose) polymerase is activated in subjects at risk of developing type 2 diabetes and is associated with impaired vascular reactivity | Q44220798 | ||
Role of poly(ADP-ribose) polymerase activation in endotoxin-induced cardiac collapse in rodents | Q44225537 | ||
Effect of poly(ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep | Q44355165 | ||
ACE inhibition salvages the visual loss caused by diabetes | Q44398243 | ||
DNA damage and antioxidant defense in peripheral leukocytes of patients with Type I diabetes mellitus | Q44466283 | ||
Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP-ribose) polymerase activation | Q44489912 | ||
Sensory neurons with activated caspase-3 survive long-term experimental diabetes | Q44564049 | ||
Intermittent high glucose enhances apoptosis related to oxidative stress in human umbilical vein endothelial cells: the role of protein kinase C and NAD(P)H-oxidase activation | Q44631833 | ||
Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy | Q44779266 | ||
Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression. | Q44940264 | ||
Intermittent high glucose enhances ICAM-1, VCAM-1, E-selectin and interleukin-6 expression in human umbilical endothelial cells in culture: the role of poly(ADP-ribose) polymerase | Q45013469 | ||
Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-kappaB. | Q45124417 | ||
Inhibitors of poly(ADP-ribose) polymerase enhance DNA strand breaks, excision repair, and sister chromatid exchanges induced by alkylating agents | Q45129882 | ||
Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury | Q47817404 | ||
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia | Q48616927 | ||
Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin. | Q52534304 | ||
ATP for the DNA ligation step in base excision repair is generated from poly(ADP-ribose). | Q52970520 | ||
Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging. | Q53850917 | ||
Proteasome activation by poly-ADP-ribose-polymerase in human myelomonocytic cells after oxidative stress. | Q54029457 | ||
Vitamin E supplementation and oxidative damage to DNA and plasma LDL in type 1 diabetes. | Q54074919 | ||
Role of oxidative-nitrosative stress and downstream pathways in various forms of cardiomyopathy and heart failure. | Q55663138 | ||
An examination of DNA strand breakage in the comet assay and antioxidant capacity in diabetic patients | Q63439778 | ||
Trans-dominant inhibition of poly(ADP-ribosyl)ation leads to decreased recovery from ionizing radiation-induced cell killing | Q64389116 | ||
P433 | issue | 11-12 | |
P921 | main subject | endothelium | Q111140 |
pathogenesis | Q372016 | ||
P304 | page(s) | 1568-1580 | |
P577 | publication date | 2005-11-01 | |
P1433 | published in | Antioxidants & Redox Signaling | Q4775078 |
P1476 | title | Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme | |
P478 | volume | 7 |
Q64106175 | ADP-ribosylation signalling and human disease |
Q41132735 | Allopregnanolone suppresses diabetes-induced neuropathic pain and motor deficit through inhibition of GABAA receptor down-regulation in the spinal cord of diabetic rats |
Q39136548 | Base excision repair of oxidative DNA damage: from mechanism to disease. |
Q36431803 | Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption |
Q35204828 | Cardiac NO signalling in the metabolic syndrome |
Q37976675 | Cellular dysfunction in diabetes as maladaptive response to mitochondrial oxidative stress |
Q48314697 | Contribution of poly(ADP-ribose) polymerase to postischemic blood-brain barrier damage in rats |
Q33609776 | Controlling the receptor for advanced glycation end-products to conquer diabetic vascular complications |
Q37741735 | Diabetic Cardiomyopathy: An Immunometabolic Perspective |
Q35691425 | Early diabetic neuropathy: triggers and mechanisms |
Q33557886 | Geniposide inhibits high glucose-induced cell adhesion through the NF-kappaB signaling pathway in human umbilical vein endothelial cells |
Q33895925 | Hind limb ischemia-reperfusion injury in diet-induced obese mice |
Q26773988 | Hyperglycemic Stress and Carbon Stress in Diabetic Glucotoxicity |
Q36355485 | Hypoxia-induced oxidative stress in ischemic retinopathy |
Q38229803 | Impaired hypoxia-inducible factor (HIF) regulation by hyperglycemia. |
Q36440020 | Influences of Diabetes on Hearing Recovery in Noise-Exposed Mice |
Q34731311 | Inhibition of poly (ADP-ribose) polymerase and inducible nitric oxide synthase protects against ischemic myocardial damage by reduction of apoptosis |
Q27001165 | Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy |
Q85642717 | Long-term phosphodiesterase 5 inhibitor administration reduces inflammatory markers and heat-shock proteins in cavernous tissue of Zucker diabetic fatty rat (ZDF/fa/fa) |
Q26773085 | Lutein, Zeaxanthin, and meso-Zeaxanthin in the Clinical Management of Eye Disease |
Q58246147 | Nephroprotective potential ofQuercus infectoriagalls against experimentally induced diabetic nephropathy in rats through inhibition of renal oxidative stress and TGF-β |
Q24645400 | Nitric oxide and peroxynitrite in health and disease |
Q57146155 | Nitrosative Stress as a Modulator of Inflammatory Change in a Model of Takotsubo Syndrome |
Q50514993 | Notch signaling protects retina from nuclear factor-κB- and poly-ADP-ribose-polymerase-mediated apoptosis under high-glucose stimulation |
Q36431798 | Novel modulators of poly(ADP-ribose) polymerase |
Q36791018 | Nuclear factor kappa B inhibition improves conductance artery function in type 2 diabetic mice |
Q38046539 | Overlapped metabolic and therapeutic links between Alzheimer and diabetes. |
Q37375332 | Oxidative stress in diabetes: implications for vascular and other complications |
Q41714460 | Oxidative toxicity in diabetes and Alzheimer's disease: mechanisms behind ROS/ RNS generation. |
Q35061401 | PARP inhibition attenuates acute kidney allograft rejection by suppressing cell death pathways and activating PI-3K-Akt cascade |
Q34670090 | PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathy |
Q28547107 | PARP-1 Inhibition Is Neuroprotective in the R6/2 Mouse Model of Huntington's Disease |
Q35004641 | PARP-1 modulates amyloid beta peptide-induced neuronal damage |
Q42142758 | Paraoxonase-1 inhibits oxidized low-density lipoprotein-induced metabolic alterations and apoptosis in endothelial cells: a nondirected metabolomic study |
Q28080057 | Pathophysiological Role of Peroxynitrite Induced DNA Damage in Human Diseases: A Special Focus on Poly(ADP-ribose) Polymerase (PARP) |
Q34314724 | Peroxynitrite-driven mechanisms in diabetes and insulin resistance - the latest advances |
Q35676519 | Pharmacological inhibition of poly(ADP-ribose) polymerase inhibits angiogenesis |
Q46208644 | Poly(ADP-ribose) polymerase activation and brain edema formation by hemoglobin after intracerebral hemorrhage in rats. |
Q36569687 | Poly(ADP-ribose) polymerase inhibition as a novel therapeutic approach against intraepidermal nerve fiber loss and neuropathic pain associated with advanced diabetic neuropathy: a commentary on "PARP Inhibition or gene deficiency counteracts intraep |
Q53253834 | Poly(ADP-ribose) polymerase is involved in the development of diabetic cystopathy via regulation of nuclear factor kappa B. |
Q81654439 | Poly(ADP-ribose) polymerase mediates inflammation in a mouse model of contact hypersensitivity |
Q46675845 | Poly(ADP-ribose)polymerase 1 inhibition protects against age-dependent endothelial dysfunction |
Q35676514 | Poly(ADP-ribose)polymerase inhibition decreases angiogenesis |
Q37172217 | Poly-ADP-ribose-polymerase inhibition ameliorates hind limb ischemia reperfusion injury in a murine model of type 2 diabetes |
Q61450534 | Potential role of poly (ADP-ribose) polymerase in delayed cerebral vasospasm following subarachnoid hemorrhage in rats |
Q50890588 | Prolonging hypothermic ischaemic cardiac and vascular storage by inhibiting the activation of the nuclear enzyme poly(adenosine diphosphate-ribose) polymerase. |
Q26752842 | Protein Modifications as Manifestations of Hyperglycemic Glucotoxicity in Diabetes and Its Complications |
Q37442978 | Redox imbalance and mitochondrial abnormalities in the diabetic lung. |
Q37023062 | Role of glyceraldehyde 3-phosphate dehydrogenase in the development and progression of diabetic retinopathy |
Q37632301 | Role of melatonin in metabolic regulation |
Q24656109 | Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies |
Q38000380 | Role of oxidative stress in diabetes-mediated vascular dysfunction: unifying hypothesis of diabetes revisited |
Q36398989 | Role of peroxynitrite in the pathogenesis of cardiovascular complications of diabetes |
Q36426742 | Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitors |
Q64892032 | Role of pseudohypoxia in the pathogenesis of type 2 diabetes. |
Q36734840 | Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease |
Q33270945 | S-nitrosoglutathione-containing hydrogel increases dermal blood flow in streptozotocin-induced diabetic rats |
Q54340577 | Sanguis draconis, a dragon's blood resin, attenuates high glucose-induced oxidative stress and endothelial dysfunction in human umbilical vein endothelial cells. |
Q28076120 | Sources and implications of NADH/NAD(+) redox imbalance in diabetes and its complications |
Q89581163 | The role of ADP-ribose metabolism in metabolic regulation, adipose tissue differentiation, and metabolism |
Q36909521 | The role of angiotensin II type 1 receptor blockers in the prevention and management of diabetes mellitus |
Q36853236 | Therapeutic applications of PARP inhibitors: anticancer therapy and beyond |
Q33643575 | Xanthine oxidase inhibitor allopurinol attenuates the development of diabetic cardiomyopathy |
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