Human autoantibody-reactive epitopes of SS-B/La are highly conserved in comparison with epitopes recognized by murine monoclonal antibodies

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Human autoantibody-reactive epitopes of SS-B/La are highly conserved in comparison with epitopes recognized by murine monoclonal antibodies is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.166.6.1627
P932PMC publication ID2188788
P698PubMed publication ID2445893

P2093author name stringE K Chan
E M Tan
P2860cites workAntibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosusQ24561667
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applicationsQ24561689
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Immunologic and structural studies of the lupus/Sjögren's syndrome autoantigen, La/SSB, with a monoclonal antibodyQ34549941
Autoantibody to RNA polymerase I in scleroderma seraQ34553988
A small nuclear ribonucleoprotein is required for splicing of adenoviral early RNA sequencesQ35318339
Association of the lupus antigen La with a subset of U6 snRNA moleculesQ36139604
Interaction between VA RNA and the lupus antigen La: formation of a ribonucleoprotein particle in vitroQ36319958
Monoclonal IgM rheumatoid factors derived from arthritic MRL/Mp-lpr/lpr miceQ36348042
The Ro/SSA autoantigen as an immunogen. Some anti-Ro/SSA antibody binds IgG.Q36353251
The small nuclear ribonucleoprotein SS-B/La binds RNA with a conserved protease-resistant domain of 28 kilodaltons.Q36843804
La antigen recognizes and binds to the 3'-oligouridylate tail of a small RNA.Q36945239
Association of La and Ro antigens with intracellular structures in HEp-2 carcinoma cellsQ37403296
Immunization of mice with purified U1 small nuclear ribonucleoprotein (RNP) induces a pattern of antibody specificities characteristic of the anti-Sm and anti-RNP autoimmune response of patients with lupus erythematosus, as measured by monoclonal anQ37407732
A host protein (La) binds to a unique species of minus-sense leader RNA during replication of vesicular stomatitis virusQ37514251
Detection of a cellular polypeptide associated with adenovirus-coded VA RNA using in vitro labeling of proteins cross-linked to RNAQ38355438
Monoclonal antibodies to the Sjögren's syndrome associated antigen SS-B (La).Q44248279
A simplified method for cyanogen bromide activation of agarose for affinity chromatographyQ47845731
Eukaryotic small ribonucleoproteins. Anti-La human autoantibodies react with U1 RNA-protein complexesQ52517851
Identification of a La protein binding site in a RNA polymerase III transcript (4.5 I RNA).Q54673450
Splicing of Xenopus laevis ribosomal protein RNAs is inhibited in vivo by antisera to ribonucleoproteins containing U1 small nuclear RNAQ63533335
Epitopes, structural domains, and asymmetry of amino acid residues in SS-B/La nuclear proteinQ64380133
A simple procedure for the isolation of IgG anti-nuclear antibodies from human serumQ67297787
Differentiation and characterization of autoantibodies and their antigens in sjögren's syndromeQ67442594
Heterogeneity of RNA protein antigens reactive with sera of patients with systemic lupus erythematosus. Description of a cytoplasmic nonribosomal antigenQ68342295
Monoclonal antibodies to a nuclear protein (PCNA/cyclin) associated with DNA replicationQ69892739
High titers of autoantibodies to topoisomerase I (Scl-70) in sera from scleroderma patientsQ70124748
Precursor molecules of both human 5S ribosomal RNA and transfer RNAs are bound by a cellular protein reactive with anti-La lupus antibodiesQ70424549
Purified lupus antigen La recognizes an oligouridylate stretch common to the 3' termini of RNA polymerase III transcriptsQ71000480
Isolation of microgram quantities of proteins from polyacrylamide gels for amino acid sequence analysisQ71746374
Splicing pathways of SV40 mRNAs in X. laevis oocytes differ in their requirements for snRNPsQ72385012
Association between the 7 S RNA and the lupus La protein varies among cell typesQ72712321
Reference sera for antinuclear antibodies. I. Antibodies to native DNA, Sm, nuclear RNP, and SS-B/LaQ72764401
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectmonoclonal antibodyQ422248
antibodyQ79460
autoantibodyQ785022
P304page(s)1627-1640
P577publication date1987-12-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleHuman autoantibody-reactive epitopes of SS-B/La are highly conserved in comparison with epitopes recognized by murine monoclonal antibodies
P478volume166

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cites work (P2860)
Q368189313'-end-dependent formation of U6 small nuclear ribonucleoprotein particles in Xenopus laevis oocyte nuclei
Q38294982A perinucleolar compartment contains several RNA polymerase III transcripts as well as the polypyrimidine tract-binding protein, hnRNP I
Q24515264A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles
Q40115476A search for structurally similar cellular internal ribosome entry sites.
Q36362080An autoimmune disease with multiple molecular targets abrogated by the transgenic expression of a single autoantigen in the thymus
Q68286140Anti-Cytoskeletal Antibodies
Q60222497Antibody fingerprints in lyme disease deciphered with high density peptide arrays
Q44246367Antimitochondrial autoantibodies in primary biliary cirrhosis recognize cross-reactive epitope(s) on protein X and dihydrolipoamide acetyltransferase of pyruvate dehydrogenase complex
Q37417504Antinuclear antibodies and juvenile chronic arthritis (JCA): search for a specific autoantibody associated with JCA.
Q41500761Autoantibodies and autoimmunity: a three-decade perspective. A tribute to Henry G. Kunkel
Q22010847Autoantibodies define a family of proteins with conserved double-stranded RNA-binding domains as well as DNA binding activity
Q34157808Autoantibodies to RNA polymerase II are common in systemic lupus erythematosus and overlap syndrome. Specific recognition of the phosphorylated (IIO) form by a subset of human sera
Q37118192Autoantibodies to tumor-associated antigens: reporters from the immune system
Q45245939Autoantibody specificity in drug-induced lupus and neutrophil-mediated metabolism of lupus-inducing drugs
Q34120989Autoantibody to hLSm4 and the heptameric LSm complex in anti-Sm sera.
Q56904720Autoimmune response to the Ro/SSA particle is directed to the human antigen
Q36362953Autoimmunity and apoptosis
Q35333291B-cell epitopes of autoantigenic DNA-binding proteins
Q34100177Binding of the La autoantigen to the 5' untranslated region of a chimeric human translation elongation factor 1A reporter mRNA inhibits translation in vitro
Q34577440Biochemical and immunological heterogeneity of the Ro ribonucleoprotein particles. Analysis with sera specific for the RohY5 particle
Q71917514Characterization of murine monoclonal antibodies against 60-kD Ro/SS-A and La/SS-B autoantigens
Q73483411Diversity of antinuclear antibody responses in hepatocellular carcinoma
Q47187009Dr Eng M. Tan: a tribute to an enduring legacy in autoimmunity
Q37424696Enzymes as targets for autoantibodies in human autoimmune disease: relevance to pathogenesis?
Q41438943Features of autoantigens.
Q24554132Functional characterization of the X-linked inhibitor of apoptosis (XIAP) internal ribosome entry site element: role of La autoantigen in XIAP translation
Q34564205Human autoantibodies to poly(adenosine diphosphate-ribose) polymerase recognize cross-reactive epitopes associated with the catalytic site of the enzyme
Q24675671Human autoantibody to RNA polymerase I transcription factor hUBF. Molecular identity of nucleolus organizer region autoantigen NOR-90 and ribosomal RNA transcription upstream binding factor
Q72077880Identification and analysis of cytochrome P450IID6 antigenic sites recognized by anti‐liver‐kidney microsome type‐1 antibodies (LKM1)
Q34172903Identification of a human-specific epitope in a conserved region of the La/SS-B autoantigen
Q72155117Immunocytochemical characterization of human NOR-90 (upstream binding factor) and associated antigens reactive with autoimmune sera. Two MR forms of NOR-90/hUBF autoantigens
Q42102527Inhibition of enzyme function by human autoantibodies to an autoantigen pyruvate dehydrogenase E2; different epitope for spontaneous human and induced rabbit autoantibodies
Q41500820Initiation of autoimmunity to self-proteins complexed with viral antigens
Q33256583Insights into native epitopes of proliferating cell nuclear antigen using recombinant DNA protein products
Q34576096Interactions between autoimmunity and molecular and cell biology. Bridges between clinical and basic sciences
Q29619024La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate
Q34569386Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1.
Q40951014Modulation of oxidative phosphorylation of human kidney 293 cells by transfection with the internal rotenone-insensitive NADH-quinone oxidoreductase (NDI1) gene of Saccharomyces cerevisiae
Q24680898Molecular characterization of an autoantigen of PM-Scl in the polymyositis/scleroderma overlap syndrome: a unique and complete human cDNA encoding an apparent 75-kD acidic protein of the nucleolar complex
Q24308428Molecular characterization of two human autoantigens: unique cDNAs encoding 95- and 160-kD proteins of a putative family in the Golgi complex
Q36252857Molecular remedy of complex I defects: rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria restores the NADH oxidase activity of complex I-deficient mammalian cells
Q33327825Neuron-specific enolase antibodies in patients with sudden acquired retinal degeneration syndrome
Q67464981Non-linear epitopes of the large subunit of Ku autoantigen recognized by monoclonal and autoantibodies
Q41140044Predicting Antigenic Determinants of Autoantigens
Q33632578Properties of the ribosomal P2 protein autoantigen are similar to those of foreign protein antigens.
Q37435327Rck/p54 interacts with APP mRNA as part of a multi-protein complex and enhances APP mRNA and protein expression in neuronal cell lines
Q35583352Relative paradigms between autoantibodies in lupus and autoantibodies in cancer
Q24635934Ribonucleoprotein SS-B/La belongs to a protein family with consensus sequences for RNA-binding
Q38328506Role of a major autoepitope in forming the DNA binding site of the p70 (Ku) antigen
Q40491923Structure and function of La and Ro RNPs
Q35723781Subcellular relocalization of a trans-acting factor regulates XIAP IRES-dependent translation.
Q57256435The HuD paraneoplastic protein shares immunogenic regions between PEM/PSN patients and several strains and species of experimental animals
Q28219090The La RNA-binding protein interacts with the vault RNA and is a vault-associated protein
Q34363735The La antigen associates with the human telomerase ribonucleoprotein and influences telomere length in vivo
Q34462937The internal ribosome entry site-mediated translation of antiapoptotic protein XIAP is modulated by the heterogeneous nuclear ribonucleoproteins C1 and C2.
Q33927166The role of an autoantigen, histidyl-tRNA synthetase, in the induction and maintenance of autoimmunity
Q46160383Use of the NADH-quinone oxidoreductase (NDI1) gene of Saccharomyces cerevisiae as a possible cure for complex I defects in human cells

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