Biology of the Sinus Node and its Disease

scientific article

Biology of the Sinus Node and its Disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.15420/AER.2015.4.1.28
P932PMC publication ID4711507
P698PubMed publication ID26835096
P5875ResearchGate publication ID277931750

P50authorGwilym M. MorrisQ40410997
P2093author name stringMark R Boyett
Moinuddin Choudhury
P2860cites workPacemaker shift in the rabbit sinoatrial node in response to vagal nerve stimulationQ74108394
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Electrophysiological and electroanatomic characterization of the atria in sinus node disease: evidence of diffuse atrial remodelingQ79749000
Anatomical diversity and age-related histological changes in the human right atrial posterolateral wallQ80150443
Sinus node disease and arrhythmias in the long-term follow-up of former professional cyclistsQ80161852
Sinus node dysfunction and hyperpolarization-activated (HCN) channel subunit remodeling in a canine heart failure modelQ81781351
Altered HCN4 channel C-linker interaction is associated with familial tachycardia-bradycardia syndrome and atrial fibrillationQ85521607
Post-shock sinus node recovery time is an independent predictor of recurrence after catheter ablation of longstanding persistent atrial fibrillationQ86054983
IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channelsQ24259024
Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channelQ24300840
Pacemaker channel dysfunction in a patient with sinus node diseaseQ24301951
Dysfunction in ankyrin-B-dependent ion channel and transporter targeting causes human sinus node diseaseQ24318595
Sinus node revisited in the era of electroanatomical mapping and catheter ablationQ24673635
Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atriaQ24681355
Modern concepts concerning the origin of the heartbeat.Q27008871
Heterogeneous expression of the delayed-rectifier K+ currents i(K,r) and i(K,s) in rabbit sinoatrial node cellsQ28354060
Bradycardia and slowing of the atrioventricular conduction in mice lacking CaV3.1/alpha1G T-type calcium channelsQ28508671
Formation of the sinus node head and differentiation of sinus node myocardium are independently regulated by Tbx18 and Tbx3Q28594589
Activation and repolarization of the normal human heart under complete physiological conditionsQ30477270
Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4Q30498016
Direct conversion of quiescent cardiomyocytes to pacemaker cells by expression of Tbx18.Q30544927
Compromising bradycardia: management in the emergency departmentQ33154658
Funny current downregulation and sinus node dysfunction associated with atrial tachyarrhythmia: a molecular basis for tachycardia-bradycardia syndrome.Q33157216
Sinus arrest in acute myocardial infarctionQ33171323
Exercise training reduces resting heart rate via downregulation of the funny channel HCN4Q33626667
Structural remodelling of the sinoatrial node in obese old ratsQ33754290
HCN2/SkM1 gene transfer into canine left bundle branch induces stable, autonomically responsive biological pacing at physiological heart ratesQ33851176
Mechanistic links between Na+ channel (SCN5A) mutations and impaired cardiac pacemaking in sick sinus syndrome.Q33982881
The sinoatrial node, a heterogeneous pacemaker structureQ34023812
The role of the funny current in pacemaker activity.Q34099619
Chronic sinoatrial disorder (sick sinus syndrome): a possible result of cardiac ischaemiaQ34118641
A novel mutation in the HCN4 gene causes symptomatic sinus bradycardia in Moroccan Jews.Q34128155
Sarcoplasmic reticulum Ca2+ pumping kinetics regulates timing of local Ca2+ releases and spontaneous beating rate of rabbit sinoatrial node pacemaker cellsQ34137927
The anatomy and physiology of the sinoatrial node--a contemporary reviewQ34143598
Biological pacemaker created by gene transferQ34149202
Biological pacemaker implanted in canine left bundle branch provides ventricular escape rhythms that have physiologically acceptable ratesQ34291219
Point mutation in the HCN4 cardiac ion channel pore affecting synthesis, trafficking, and functional expression is associated with familial asymptomatic sinus bradycardiaQ34655363
Hyperpolarization-activated cation currents: from molecules to physiological functionQ35019781
Acute thrombosis of the sinus node artery: arrhythmological implicationsQ35580843
Abnormal response of superior sinoatrial node to sympathetic stimulation is a characteristic finding in patients with atrial fibrillation and symptomatic bradycardia.Q35638679
What keeps us ticking: a funny current, a calcium clock, or both?Q36010630
HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in miceQ36116647
SCN5A and sinoatrial node pacemaker function.Q36763211
Biological pacemaker created by minimally invasive somatic reprogramming in pigs with complete heart block.Q37105417
Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5.Q37222054
Sodium channel mutations and arrhythmiasQ37450777
Development of the pacemaker tissues of the heart.Q37687712
Fibrosis, electrics and genetics. Perspectives in sinoatrial node diseaseQ38212507
Quantitative histological analysis of the human sinoatrial node during growth and agingQ39240007
The transcriptional repressor Tbx3 delineates the developing central conduction system of the heart.Q40553027
Cardiac pacemaking in the sinoatrial nodeQ40850880
Origin of the sinus impulseQ41160923
Excitation-contraction coupling in heart: new insights from Ca2+ sparksQ41186337
Pathological studies in sinoatrial disorder (sick sinus syndrome).Q41329934
Optical mapping of the isolated coronary-perfused human sinus nodeQ41432043
The origins of the sinus node pacemaker complex in man: demonstration of dominant and subsidiary fociQ41477766
Appraisal of sinus node artery diseaseQ41966659
Local control of Ca2+-induced Ca2+ release in mouse sinoatrial node cells.Q42583209
Catecholaminergic polymorphic ventricular tachycardia: RYR2 mutations, bradycardia, and follow up of the patients.Q43073409
Computer three-dimensional anatomical reconstruction of the human sinus node and a novel paranodal areaQ43522285
Role of sinus node artery disease in sick sinus syndrome in inferior wall acute myocardial infarctionQ43611266
Sinoatrial nodal cell ryanodine receptor and Na(+)-Ca(2+) exchanger: molecular partners in pacemaker regulationQ43649137
Pacemaking in rabbit isolated sino-atrial node cells during Cs+ block of the hyperpolarization-activated current if.Q44315978
Characterization of a right atrial subsidiary pacemaker and acceleration of the pacing rate by HCN over-expressionQ45888497
Molecular architecture of the human sinus node: insights into the function of the cardiac pacemakerQ46535702
Declining into failure: the age-dependent loss of the L-type calcium channel within the sinoatrial nodeQ46939081
Sinus pacemaker function after cardioversion of chronic atrial fibrillation: is sinus node remodeling related with recurrence?Q51351930
T-box transcription factor TBX3 reprogrammes mature cardiac myocytes into pacemaker-like cells.Q51803470
Computer three-dimensional reconstruction of the sinoatrial node.Q51978382
TGF-β1-mediated fibrosis and ion channel remodeling are key mechanisms in producing the sinus node dysfunction associated with SCN5A deficiency and aging.Q52610086
Ageing-related changes of connexins and conduction within the sinoatrial node.Q52858881
The mode selection trial (MOST) in sinus node dysfunction: design, rationale, and baseline characteristics of the first 1000 patients.Q53511396
Viewpoint: Is the resting bradycardia in athletes the result of remodeling of the sinoatrial node rather than high vagal tone?Q59594714
Ageing-dependent remodelling of ion channel and Ca2+clock genes underlying sino-atrial node pacemakingQ59594719
Organisation of the mouse sinoatrial node: structure and expression of HCN channelsQ59594730
Differential Expression of Ion Channel Transcripts in Atrial Muscle and Sinoatrial Node in RabbitQ59594734
Pathology of sinoatrial node. Correlations with electrocardiographic findings in 111 patientsQ67584160
Electrophysiology and ultrastructure of eustachian ridge from cat right atrium: a comparison with SA nodeQ68674131
Guidelines for clinical intracardiac electrophysiologic studies. A report of the American College of Cardiology/American Heart Association Task Force on Assessment of Diagnostic and Therapeutic Cardiovascular Procedures (Subcommittee to Assess CliniQ69386132
Electrophysiology of normal sinus node with and without autonomic blockadeQ70333601
Functional and morphological organization of the rabbit sinus nodeQ71127555
Pacing-induced chronic atrial fibrillation impairs sinus node function in dogs. Electrophysiological remodelingQ71828372
Comparative ultrastructure of the sinus node in man and dogQ72861531
Electrical remodeling of the atria associated with paroxysmal and chronic atrial flutterQ73054097
P433issue1
P304page(s)28-34
P577publication date2015-05-30
P1433published inArrhythmia & electrophysiology reviewQ27727082
P1476titleBiology of the Sinus Node and its Disease
P478volume4

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cites work (P2860)
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Q91643474Risk factors and a 3-month risk score for predicting pacemaker implantation in patients with atrial fibrillations
Q42379949Tbx18 and the generation of a biological pacemaker. Are we there yet?

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