| scholarly article | Q13442814 |
| P50 | author | Myriam Gorospe | Q19766141 |
| Josephine M. Egan | Q88222602 | ||
| Olga D Carlson | Q88964164 | ||
| P2093 | author name string | Wook Kim | |
| Rohit N Kulkarni | |||
| Eun Kyung Lee | |||
| Yu-Kyong Shin | |||
| Qizong Lao | |||
| P2860 | cites work | Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor | Q22009126 |
| AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1 | Q22254000 | ||
| Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose | Q24299251 | ||
| Disruption of IRS-2 causes type 2 diabetes in mice | Q24316112 | ||
| Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery | Q27860586 | ||
| Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization | Q28202083 | ||
| Leptin-regulated endocannabinoids are involved in maintaining food intake | Q28211969 | ||
| Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet | Q46779281 | ||
| Presence of functional cannabinoid receptors in human endocrine pancreas | Q46842198 | ||
| p27 Regulates the transition of beta-cells from quiescence to proliferation | Q46941946 | ||
| Relationship between beta-cell mass and fasting blood glucose concentration in humans | Q46966775 | ||
| Blockade of cannabinoid CB1 receptors improves renal function, metabolic profile, and increased survival of obese Zucker rats | Q46991382 | ||
| Insulin-induced protein tyrosine phosphorylation cascade and signalling molecules are localized in a caveolin-enriched cell membrane domain | Q47734800 | ||
| Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes. | Q54104864 | ||
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| The role of insulin receptor kinase domain autophosphorylation in receptor-mediated activities. Analysis with insulin and anti-receptor antibodies | Q67852255 | ||
| Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice | Q81348403 | ||
| Cell death: critical control points | Q28240722 | ||
| p16INK4a induces an age-dependent decline in islet regenerative potential | Q28262230 | ||
| The emerging role of the endocannabinoid system in endocrine regulation and energy balance | Q28283398 | ||
| Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L) | Q28297419 | ||
| Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice | Q28343324 | ||
| p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis | Q28365491 | ||
| The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth | Q28508976 | ||
| Identification of the insulin receptor tyrosine residues undergoing insulin-stimulated phosphorylation in intact rat hepatoma cells | Q28568902 | ||
| The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling | Q28615445 | ||
| Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes | Q28615460 | ||
| Cellular survival: a play in three Akts | Q29547806 | ||
| Critical nodes in signalling pathways: insights into insulin action | Q29614735 | ||
| Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog | Q29616450 | ||
| Structure and function of sphingolipid- and cholesterol-rich membrane rafts | Q29618518 | ||
| Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes | Q29619192 | ||
| Cannabinoid receptors as novel targets for the treatment of melanoma | Q31070295 | ||
| Efficacy and safety of rimonabant for improvement of multiple cardiometabolic risk factors in overweight/obese patients: pooled 1-year data from the Rimonabant in Obesity (RIO) program | Q31144410 | ||
| Regulation of MAP kinase-directed mitogenic and protein kinase B-mediated signaling by cannabinoid receptor type 1 in skeletal muscle cells | Q33604478 | ||
| Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines | Q33903502 | ||
| Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition. | Q34049715 | ||
| PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization | Q34150579 | ||
| Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells | Q34718769 | ||
| Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice | Q36800423 | ||
| Modulation of the endocannabinoid system by lipid rafts. | Q36990258 | ||
| Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development | Q37223903 | ||
| Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding | Q37376946 | ||
| The role of the pancreatic endocannabinoid system in glucose metabolism. | Q37414558 | ||
| The endocannabinoid system: role in glucose and energy metabolism | Q37532973 | ||
| Effects of the cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in Lep(ob)/Lep(ob) mice | Q38333962 | ||
| Streptozotocin-Induced Pancreatic Insulitis: New Model of Diabetes Mellitus | Q39998473 | ||
| Cannabinoid receptor agonist-induced apoptosis of human prostate cancer cells LNCaP proceeds through sustained activation of ERK1/2 leading to G1 cell cycle arrest | Q40214988 | ||
| Regulation, function, and dysregulation of endocannabinoids in models of adipose and beta-pancreatic cells and in obesity and hyperglycemia | Q40282032 | ||
| Plasma membrane and lysosomal localization of CB1 cannabinoid receptor are dependent on lipid rafts and regulated by anandamide in human breast cancer cells | Q40355791 | ||
| Insulin receptor autophosphorylation. II. Determination of autophosphorylation sites by chemical sequence analysis and identification of the juxtamembrane sites | Q41547914 | ||
| Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2. | Q41870014 | ||
| Absence of caspase-3 protects pancreatic {beta}-cells from c-Myc-induced apoptosis without leading to tumor formation. | Q42006448 | ||
| Caspase-3-dependent beta-cell apoptosis in the initiation of autoimmune diabetes mellitus. | Q42724764 | ||
| Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha | Q43759225 | ||
| FoxO1a can alter cell cycle progression by regulating the nuclear localization of p27kip in granulosa cells. | Q44846727 | ||
| Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle | Q46194510 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 216 | |
| P921 | main subject | cell death | Q2383867 |
| preproinsulin | Q7240673 | ||
| cannabinoid receptor | Q421237 | ||
| cannabinoids | Q422936 | ||
| CNR2 | Q17907844 | ||
| P304 | page(s) | ra23 | |
| P577 | publication date | 2012-03-20 | |
| P1433 | published in | Science Signaling | Q7433604 |
| P1476 | title | Cannabinoids induce pancreatic β-cell death by directly inhibiting insulin receptor activation | |
| P478 | volume | 5 |
| Q47407342 | A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis |
| Q51246185 | Absence of cannabinoid 1 receptor in beta cells protects against high-fat/high-sugar diet-induced beta cell dysfunction and inflammation in murine islets. |
| Q33731729 | Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes |
| Q35582616 | Alterations in the Medullary Endocannabinoid System Contribute to Age-related Impairment of Baroreflex Sensitivity |
| Q36578199 | Blockade of cannabinoid 1 receptor improves GLP-1R mediated insulin secretion in mice. |
| Q50068640 | Blockade of cannabinoid 1 receptor improves glucose responsiveness in pancreatic beta cells. |
| Q91710019 | Brain Metabolism Alterations in Type 2 Diabetes: What Did We Learn From Diet-Induced Diabetes Models? |
| Q37289307 | CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release |
| Q35953952 | Cannabinoids Regulate Bcl-2 and Cyclin D2 Expression in Pancreatic β Cells |
| Q36373581 | Controlled downregulation of the cannabinoid CB1 receptor provides a promising approach for the treatment of obesity and obesity-derived type 2 diabetes |
| Q34650930 | Effects of CB1 receptor blockade on monosodium glutamate induced hypometabolic and hypothalamic obesity in rats |
| Q28078897 | Endocannabinoid regulation of β-cell functions: implications for glycaemic control and diabetes |
| Q88924595 | Endocannabinoids in Body Weight Control |
| Q88308934 | Endocannabinoids in the Islets of Langerhans: the ugly, the bad, and the good facts |
| Q36300457 | Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture |
| Q58778548 | Glucose Controls the Expression of Polypyrimidine Tract-Binding Protein 1 via the Insulin Receptor Signaling Pathway in Pancreatic β Cells |
| Q35157007 | Gαi/o-coupled receptor signaling restricts pancreatic β-cell expansion |
| Q37264554 | Human CB1 Receptor Isoforms, present in Hepatocytes and β-cells, are Involved in Regulating Metabolism |
| Q36182559 | Human β-cell proliferation and intracellular signaling: driving in the dark without a road map. |
| Q26821954 | Human β-cell proliferation and intracellular signaling: part 3 |
| Q57061734 | Impact of maternal western diet-induced obesity on offspring mortality and peripheral endocannabinoid system in mice |
| Q92905171 | Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression |
| Q37022702 | Metabolic effects of chronic cannabis smoking |
| Q38038661 | Modulation of β-cell function: a translational journey from the bench to the bedside |
| Q34494301 | New insights on the role of the endocannabinoid system in the regulation of energy balance. |
| Q38016798 | New vistas for treatment of obesity and diabetes? Endocannabinoid signalling and metabolism in the modulation of energy balance. |
| Q90052790 | Novel CB1 receptor antagonist BAR-1 modifies pancreatic islet function and clinical parameters in prediabetic and diabetic mice |
| Q51091657 | Overactivation of the endocannabinoid system alters the antilipolytic action of insulin in mouse adipose tissue. |
| Q36799355 | Prolonged activation of human islet cannabinoid receptors in vitro induces adaptation but not dysfunction |
| Q90266473 | Reduced expression of the RNA-binding protein HuD in pancreatic neuroendocrine tumors correlates with low p27Kip1 levels and poor prognosis |
| Q64889523 | Role of Cannabinoid Receptor Type 1 in Insulin Resistance and Its Biological Implications. |
| Q37085532 | Role of the endocannabinoid system in diabetes and diabetic complications |
| Q35840211 | The cannabinoid CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice. |
| Q33822403 | The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice. |
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