A small novel A-kinase anchoring protein (AKAP) that localizes specifically protein kinase A-regulatory subunit I (PKA-RI) to the plasma membrane.

scientific article

A small novel A-kinase anchoring protein (AKAP) that localizes specifically protein kinase A-regulatory subunit I (PKA-RI) to the plasma membrane. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M112.395970
P932PMC publication ID3527963
P698PubMed publication ID23115245

P50authorAlbert J.R. HeckQ2865808
Marcel van der HeydenQ70859936
P2093author name stringSusan S Taylor
Arjen Scholten
Mark Ellisman
Mason Mackey
Luigi Margarucci
Yuliang Ma
Pepijn P Burgers
P2860cites workAlternative splicing regulates the subcellular localization of A-kinase anchoring protein 18 isoformsQ22010992
Sphingosine kinase interacting protein is an A-kinase anchoring protein specific for type I cAMP-dependent protein kinaseQ24306725
D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domainQ24317008
Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolaeQ24323219
A genetically encoded tag for correlated light and electron microscopy of intact cells, tissues, and organismsQ27321551
PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activationQ27648438
Novel Isoform-Specific Interfaces Revealed by PKA RIIβ Holoenzyme StructuresQ27657420
Structure of D-AKAP2:PKA RI Complex: Insights into AKAP Specificity and SelectivityQ27659870
Crystal structure of the Aequorea victoria green fluorescent proteinQ27733214
Palmitoylation of intracellular signaling proteins: regulation and functionQ28266189
Interaction of the regulatory subunit (RII) of cAMP-dependent protein kinase with RII-anchoring proteins occurs through an amphipathic helix binding motifQ28286420
Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunitsQ28305592
Phosphorylation-Dephosphorylation of EnzymesQ28306047
An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondriaQ28509852
AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulumQ28571497
Palmitoylation targets AKAP79 protein to lipid rafts and promotes its regulation of calcium-sensitive adenylyl cyclase type 8Q28583315
AKAP signalling complexes: focal points in space and timeQ29618533
Protein myristoylation in health and diseaseQ33631172
Site-specific analysis of protein S-acylation by resin-assisted captureQ34147620
Trafficking and signaling by fatty-acylated and prenylated proteinsQ34575170
Palmitoylation of ligands, receptors, and intracellular signaling moleculesQ34578256
Isoform-specific targeting of PKA to multivesicular bodiesQ34825113
Designing isoform-specific peptide disruptors of protein kinase A localizationQ34921315
Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysisQ35591725
AKAPs (A-kinase anchoring proteins) and molecules that compose their G-protein-coupled receptor signalling complexesQ35625359
A multi-angular mass spectrometric view at cyclic nucleotide dependent protein kinases: in vivo characterization and structure/function relationshipsQ37125448
High-affinity binding of the regulatory subunit (RII) of cAMP-dependent protein kinase to microtubule-associated and other cellular proteinsQ37575501
Compartmentalization of adenosine 3':5'-monophosphate and adenosine 3':5'-monophosphate-dependent protein kinase in heart tissueQ39148490
Studies on the properties and mode of action of the purified regulatory subunit of bovine heart adenosine 3‘:5‘-monophosphate-dependent protein kinaseQ40146034
Analysis of the cGMP/cAMP interactome using a chemical proteomics approach in mammalian heart tissue validates sphingosine kinase type 1-interacting protein as a genuine and highly abundant AKAP.Q40273003
Delineation of type I protein kinase A-selective signaling events using an RI anchoring disruptorQ40275163
Rab32 is an A-kinase anchoring protein and participates in mitochondrial dynamicsQ40709834
Mice with disrupted type I protein kinase A anchoring in T cells resist retrovirus-induced immunodeficiencyQ42485726
A single transient episode of hyperammonemia induces long-lasting alterations in protein kinase A.Q42506655
Distinct interaction modes of an AKAP bound to two regulatory subunit isoforms of protein kinase A revealed by amide hydrogen/deuterium exchangeQ43057814
Probing the specificity of protein-protein interactions by quantitative chemical proteomicsQ43932906
Alpha4 integrins are type I cAMP-dependent protein kinase-anchoring proteinsQ46196570
Molecular characterization of an anchor protein (AKAPCE) that binds the RI subunit (RCE) of type I protein kinase A from Caenorhabditis elegansQ48034341
Novel chromophores and buried charges control color in mFruits.Q50476950
Isoform-specific PKA dynamics revealed by dye-triggered aggregation and DAKAP1alpha-mediated localization in living cells.Q50664657
Protein kinase A type I and type II define distinct intracellular signaling compartments.Q51786668
Reorganized PKA-AKAP associations in the failing human heart.Q54578401
Collagen stimulation of platelets induces a rapid spatial response of cAMP and cGMP signaling scaffolds.Q54588544
Diversity of cAMP-Dependent Protein Kinase Isoforms and Their Anchoring Proteins in Mouse Ventricular TissueQ57666220
Cyclic adenosine 3',5'-monophosphate-dependent protein kinase of human erythrocyte membranesQ68655624
Functional compartmentation of cyclic AMP and protein kinase in heartQ72907708
Molecular basis of AKAP specificity for PKA regulatory subunitsQ79326012
Enzyme free cloning for high throughput gene cloning and expressionQ79761801
Oxidant-induced activation of type I protein kinase A is mediated by RI subunit interprotein disulfide bond formationQ83929489
P4510describes a project that usesImageJQ1659584
P433issue52
P407language of work or nameEnglishQ1860
P304page(s)43789-43797
P577publication date2012-10-31
P1433published inJournal of Biological ChemistryQ867727
P1476titleA small novel A-kinase anchoring protein (AKAP) that localizes specifically protein kinase A-regulatory subunit I (PKA-RI) to the plasma membrane
P478volume287

Reverse relations

cites work (P2860)
Q26782981A dynamic interface between ubiquitylation and cAMP signaling
Q38240756A-kinase anchoring proteins: cAMP compartmentalization in neurodegenerative and obstructive pulmonary diseases
Q37427846AKAP signaling complexes: pointing towards the next generation of therapeutic targets?
Q39831939AKAP18:PKA-RIIα structure reveals crucial anchor points for recognition of regulatory subunits of PKA.
Q36021791An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes
Q64280822An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma
Q60046306An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactions
Q57292461An optogenetic toolbox of LOV-based photosensitizers for light-driven killing of bacteria
Q38248672Anchored protein kinase A signalling in cardiac cellular electrophysiology
Q38902450Applications of genetically encoded photosensitizer miniSOG: from correlative light electron microscopy to immunophotosensitizing.
Q34805867D-AKAP2:PKA RII:PDZK1 ternary complex structure: insights from the nucleation of a polyvalent scaffold
Q89651590Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - A missed opportunity
Q28550544Extracting Diffusive States of Rho GTPase in Live Cells: Towards In Vivo Biochemistry
Q90093890Gravin gravitates atherogenesis to atheroprogression in the obesogenic setting
Q92703368Hedgehog and Gpr161: Regulating cAMP Signaling in the Primary Cilium
Q35199457Huntingtin-associated protein 1 (HAP1) is a cGMP-dependent kinase anchoring protein (GKAP) specific for the cGMP-dependent protein kinase Iβ isoform.
Q37572127Inactivation of the Carney complex gene 1 (PRKAR1A) alters spatiotemporal regulation of cAMP and cAMP-dependent protein kinase: a study using genetically encoded FRET-based reporters
Q38732399Isoform-selective disruption of AKAP-localized PKA using hydrocarbon stapled peptides
Q37634289Isoform-specific subcellular localization and function of protein kinase A identified by mosaic imaging of mouse brain.
Q50097180Light-induced oxidant production by fluorescent proteins.
Q35762738PKA-type I selective constrained peptide disruptors of AKAP complexes
Q26823926PKA: lessons learned after twenty years
Q36744738Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor: EFFECT ON PKA LOCALIZATION AND P-Rex1 SIGNALING
Q35925772Protein Kinase A Opposes the Phosphorylation-dependent Recruitment of Glycogen Synthase Kinase 3β to A-kinase Anchoring Protein 220
Q38218419Role of soluble adenylyl cyclase in mitochondria
Q52809588Roles of A-Kinase Anchoring Proteins and Phosphodiesterases in the Cardiovascular System.
Q64059542Serine/Threonine Protein Kinase STK16
Q28546402Single Turnover Autophosphorylation Cycle of the PKA RIIβ Holoenzyme
Q40964114Spatiotemporal regulation of cAMP signaling controls the human trophoblast fusion
Q37165563Structure of smAKAP and its regulation by PKA-mediated phosphorylation.
Q26748559Targeting cAMP/PKA pathway for glycemic control and type 2 diabetes therapy
Q40734560Targeting of type I protein kinase A to lipid rafts is required for platelet inhibition by the 3',5'-cyclic adenosine monophosphate-signaling pathway.
Q26781574Targeting protein-protein interactions in complexes organized by A kinase anchoring proteins
Q41811866The Spatiotemporal Regulation of cAMP Signaling in Blood Platelets-Old Friends and New Players
Q38197316The control of blood platelets by cAMP signalling

Search more.