Isoform-selective disruption of AKAP-localized PKA using hydrocarbon stapled peptides

scientific article published on 21 January 2014

Isoform-selective disruption of AKAP-localized PKA using hydrocarbon stapled peptides is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/CB400900R
P932PMC publication ID3985448
P698PubMed publication ID24422448

P50authorFriedrich W. HerbergQ1462688
Daniela BertinettiQ38589432
Eileen J KennedyQ56808152
P2093author name stringJin Zhang
Yuxiao Wang
Eugen Franz
Tienhuei G Ho
Matthias Neddermann
Gary C H Mo
Avinash Sukhu
Lewis P Schendowich
Raybun C Spelts
P2860cites workAssociation of the type II cAMP-dependent protein kinase with a human thyroid RII-anchoring protein. Cloning and characterization of the RII-binding domainQ24336977
PKA: lessons learned after twenty yearsQ26823926
Assembly of allosteric macromolecular switches: lessons from PKAQ26852228
Structure of D-AKAP2:PKA RI Complex: Insights into AKAP Specificity and SelectivityQ27659870
Analysis of A-kinase anchoring protein (AKAP) interaction with protein kinase A (PKA) regulatory subunits: PKA isoform specificity in AKAP bindingQ28141713
Networking with AKAPs: context-dependent regulation of anchored enzymesQ28278715
A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinaseQ28574420
Disruption of protein kinase A localization using a trans-activator of transcription (TAT)-conjugated A-kinase-anchoring peptide reduces cardiac functionQ30496446
Stapled peptides for intracellular drug targetsQ34245833
Dynamics of cAMP-dependent protein kinaseQ34465979
The challenge of drugging undruggable targets in cancer: lessons learned from targeting BCL-2 family membersQ34727955
A-kinase anchoring proteins: scaffolding proteins in the heart.Q35543502
A-kinase anchoring proteins as potential drug targetsQ36159125
A small novel A-kinase anchoring protein (AKAP) that localizes specifically protein kinase A-regulatory subunit I (PKA-RI) to the plasma membrane.Q36481868
Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptidesQ37018294
A-kinase anchoring proteins: from protein complexes to physiology and diseaseQ37192490
Adenylyl cyclase--A-kinase anchoring protein complexes: the next dimension in cAMP signalingQ37415827
Mechanisms of protein kinase A anchoringQ37783810
AKAP signaling complexes in regulation of excitatory synaptic plasticityQ37865993
Promotion and inhibition of cardiac hypertrophy by A-kinase anchor proteinsQ38031570
Visualization of PKA activity in plasma membrane microdomainsQ39656249
Delineation of type I protein kinase A-selective signaling events using an RI anchoring disruptorQ40275163
Isoform-specific differences between the type Ialpha and IIalpha cyclic AMP-dependent protein kinase anchoring domains revealed by solution NMR.Q41748115
Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motilityQ42529103
Imaging CREB activation in living cells.Q42724362
Distinct interaction modes of an AKAP bound to two regulatory subunit isoforms of protein kinase A revealed by amide hydrogen/deuterium exchangeQ43057814
Chemical tools selectively target components of the PKA systemQ43156539
Active site mutations define the pathway for the cooperative activation of cAMP-dependent protein kinaseQ44763989
Ring-closing metathesis of olefinic peptides: design, synthesis, and structural characterization of macrocyclic helical peptides.Q46228530
Molecular basis of AKAP specificity for PKA regulatory subunitsQ79326012
P433issue3
P304page(s)635-642
P577publication date2014-01-21
P1433published inACS Chemical BiologyQ165583
P1476titleIsoform-selective disruption of AKAP-localized PKA using hydrocarbon stapled peptides
P478volume9

Reverse relations

cites work (P2860)
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