scholarly article | Q13442814 |
P2093 | author name string | Frank R Jirik | |
Shigeki Tsutsui | |||
Trina A Johnson | |||
P2860 | cites work | Tissue- and site-specific DNA recombination in transgenic mice | Q21999077 |
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus | Q24797230 | ||
Modelling T-cell memory by genetic marking of memory T cells in vivo | Q28137842 | ||
PTEN: life as a tumor suppressor | Q28203431 | ||
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
Specificity, magnitude, and kinetics of MOG-specific CD8+ T cell responses during experimental autoimmune encephalomyelitis | Q81129297 | ||
Immunology of multiple sclerosis | Q81531267 | ||
Pten is essential for embryonic development and tumour suppression | Q28509238 | ||
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems | Q28586004 | ||
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome | Q29615538 | ||
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors | Q29616203 | ||
CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. | Q34300766 | ||
Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1). | Q34381917 | ||
A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice | Q34381923 | ||
PTEN inhibits IL-2 receptor-mediated expansion of CD4+ CD25+ Tregs | Q34997285 | ||
The CD4-Th1 model for multiple sclerosis: a critical [correction of crucial] re-appraisal | Q35702792 | ||
Do phosphoinositide 3-kinases direct lymphocyte navigation? | Q35753100 | ||
CD8+ T cells control the TH phenotype of MBP-reactive CD4+ T cells in EAE mice | Q35940569 | ||
Regulatory functions of CD8+CD28– T cells in an autoimmune disease model | Q36001202 | ||
Leukocytes on the move with phosphoinositide 3-kinase and its downstream effectors | Q36017999 | ||
The role of CD8(+) T cells in multiple sclerosis and its animal models | Q36107655 | ||
Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy? | Q36173589 | ||
Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction | Q36368672 | ||
A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis | Q36376307 | ||
Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis | Q36384467 | ||
The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling | Q36403817 | ||
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. | Q36457107 | ||
The Pten/PI3K pathway governs the homeostasis of Valpha14iNKT cells. | Q40196116 | ||
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice. | Q41377207 | ||
Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis | Q44002202 | ||
A1 adenosine receptor upregulation and activation attenuates neuroinflammation and demyelination in a model of multiple sclerosis. | Q44762699 | ||
Selective expression of the Cre recombinase in late-stage thymocytes using the distal promoter of the Lck gene. | Q46039047 | ||
p27Kip1 is required for PTEN-induced G1 growth arrest. | Q46585082 | ||
Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner | Q46952728 | ||
Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease | Q47198015 | ||
Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions | Q48338419 | ||
A transgenic mouse model genetically tags all activated CD8 T cells. | Q52006066 | ||
Cytokine-stimulated T lymphocyte proliferation is regulated by p27Kip1. | Q52023151 | ||
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. | Q52126962 | ||
TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination. | Q54150165 | ||
An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization. | Q54650311 | ||
T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance | Q57185252 | ||
High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice | Q57272679 | ||
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice | Q58378937 | ||
Multiple Sclerosis: Distribution of T Cell Subsets Within Active Chronic Lesions | Q72773066 | ||
Impaired Fas response and autoimmunity in Pten+/- mice | Q73019160 | ||
Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice | Q73966732 | ||
Experimental autoimmune encephalomyelitis mediated by CD8+ T cells | Q80005390 | ||
Cutting edge: T cell requirement for CD28 costimulation is due to negative regulation of TCR signals by PTEN | Q80283949 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 980-992 | |
P577 | publication date | 2008-03-18 | |
P1433 | published in | The American Journal of Pathology | Q4744259 |
P1476 | title | Antigen-induced Pten gene deletion in T cells exacerbates neuropathology in experimental autoimmune encephalomyelitis | |
P478 | volume | 172 |
Q37711026 | Exploring the roles of CD8(+) T lymphocytes in the pathogenesis of autoimmune demyelination |
Q34253257 | Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination |
Q38732326 | Smad4 deficiency in T cells leads to the Th17-associated development of premalignant gastroduodenal lesions in mice |