Why is it challenging to predict intestinal drug absorption and oral bioavailability in human using rat model.

scientific article published on August 2006

Why is it challenging to predict intestinal drug absorption and oral bioavailability in human using rat model. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S11095-006-9041-2
P698PubMed publication ID16841194
P5875ResearchGate publication ID6944878

P50authorDuxin SunQ95935419
Xianhua CaoQ114413498
Ho-chul ShinQ42630718
Christopher P. LandowskiQ44684419
Gordon L. AmidonQ56166547
P2093author name stringYanqiang Zhong
Lawrence X Yu
Lanyan Fang
Hans Lennernas
Seth T Gibbs
Heather A Miller
P2860cites workcDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3)1Q24314274
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Is the role of the small intestine in first-pass metabolism overemphasized?Q33650100
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STUDIES ON THE ABSORPTION, METABOLISM AND EXCRETION OF METHYLDOPA AND OTHER CATECHOLS AND THEIR INFLUENCE ON AMINO ACID TRANSPORT IN RATSQ76958530
Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugsQ78498262
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P433issue8
P921main subjectbioavailabilityQ461809
P304page(s)1675-1686
P577publication date2006-08-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inPharmaceutical ResearchQ7180737
P1476titleWhy is it challenging to predict intestinal drug absorption and oral bioavailability in human using rat model
P478volume23

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