KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway

scientific article published on 5 February 2016

KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SREP20460
P932PMC publication ID4742820
P698PubMed publication ID26847701
P5875ResearchGate publication ID293193134

P2093author name stringXin Wang
Fen Wang
Ru-Hua Zhang
Liping Li
Haojie Huang
Tiebang Kang
Yuanzhong Wu
Suihai Wang
Meifang Zhang
Tingmei Duan
P2860cites workProliferative effects of gamma-aminobutyric acid on the gastric cancer cell line are associated with extracellular signal-regulated kinase 1/2 activationQ39912532
Baclofen, a GABAB receptor agonist, inhibits human hepatocellular carcinoma cell growth in vitro and in vivoQ40020306
Imatinib inhibits colorectal cancer cell growth and suppresses stromal-induced growth stimulation, MT1-MMP expression and pro-MMP2 activation.Q40089045
GABAB receptor constituents revealed by tandem affinity purification from transgenic miceQ42572060
GABA receptor expression in benign and malignant thyroid tumorsQ46043055
Pfetin as a Prognostic Biomarker for Gastrointestinal Stromal Tumor: Validation Study in Multiple Clinical FacilitiesQ51009751
Effect of gamma-butyrolactone on baclofen inhibition of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar ratsQ53493428
Pfetin as a prognostic biomarker of gastrointestinal stromal tumors revealed by proteomics.Q54541752
Colorectal cancerQ57191694
GABA content and GAD activity in colon tumors taken from patients with colon cancer or from xenografted human colon cancer cells growing as s.c. tumors in athymic nu/nu miceQ74789714
GABAergic signaling facilitates breast cancer metastasis by promoting ERK1/2-dependent phosphorylationQ87495024
Isolation from cochlea of a novel human intronless gene with predominant fetal expressionQ24650440
Identification and expansion of human colon-cancer-initiating cellsQ27860627
Native GABA(B) receptors are heteromultimers with a family of auxiliary subunitsQ28507921
Genetic screens in human cells using the CRISPR-Cas9 systemQ29617411
Tumour stem cells and drug resistanceQ29617742
Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma.Q33864635
The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapseQ34171959
Colorectal cancer statistics, 2014.Q34660408
Altered emotionality and neuronal excitability in mice lacking KCTD12, an auxiliary subunit of GABAB receptors associated with mood disordersQ35653895
GABAB Receptor Complex as a Potential Target for Tumor TherapyQ35956277
The MAPK signalling pathways and colorectal cancerQ36111490
Novel approaches to treatment of advanced colorectal cancer with anti-EGFR monoclonal antibodiesQ36793661
Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity.Q36869902
REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastomaQ36987393
Complex GABAB receptor complexes: how to generate multiple functionally distinct units from a single receptor.Q37576739
Role of SLC6A6 in promoting the survival and multidrug resistance of colorectal cancer.Q37733017
Colorectal Cancer Stem CellsQ37974613
MicroRNAs predict and modulate responses to chemotherapy in colorectal cancer.Q38552402
Afatinib enhances the efficacy of conventional chemotherapeutic agents by eradicating cancer stem-like cellsQ38980268
Lgr5 promotes cancer stemness and confers chemoresistance through ABCB1 in colorectal cancerQ39076965
Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylationQ39750898
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectcolorectal cancerQ188874
colorectal carcinomaQ25493920
P304page(s)20460
P577publication date2016-02-05
P1433published inScientific ReportsQ2261792
P1476titleKCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway
P478volume6

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cites work (P2860)
Q57477014APOBEC1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver
Q58696815Contribution of KCTD12 to esophageal squamous cell carcinoma
Q64079753DRUM: Inference of Disease-Associated mA RNA Methylation Sites From a Multi-Layer Heterogeneous Network
Q90357675Downregulation of KCTD12 contributes to melanoma stemness by modulating CD271
Q90620137KCTD12 promotes G1/S transition of breast cancer cell through activating the AKT/FOXO1 signaling
Q47113243KCTD12 promotes tumorigenesis by facilitating CDC25B/CDK1/Aurora A-dependent G2/M transition.
Q42374193Mechanistic Evaluation and Translational Signature of Gemcitabine-induced Chemoresistance by Quantitative Phosphoproteomics Analysis with iTRAQ Labeling Mass Spectrometry

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