Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data

scientific article published on April 1, 1971

Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data is …
instance of (P31):
scholarly articleQ13442814

External links are
P698PubMed publication ID5580011

P2093author name stringA. Zarins
H. J. Mankin
L. Lippiello
H. Dorfman
P433issue3
P407language of work or nameEnglishQ1860
P921main subjecthead of femurQ582849
articular cartilageQ3704713
cartilageQ502730
P304page(s)523-537
P577publication date1971-04-01
P1433published inJournal of Bone and Joint SurgeryQ6294867
P1476titleBiochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data
P478volume53

Reverse relations

cites work (P2860)
Q47594075"Patient reported outcomes" following experimental surgery-using telemetry to assess movement in experimental ovine models
Q47798692* The Ovine Model for Meniscus Tissue Engineering: Considerations of Anatomy, Function, Implantation, and Evaluation.
Q3380637523Na MRI accurately measures fixed charge density in articular cartilage
Q480254163D histopathological grading of osteochondral tissue using contrast-enhanced micro-computed tomography
Q60912716A Complex Relationship between Visfatin and Resistin and microRNA: An In Vitro Study on Human Chondrocyte Cultures
Q34978086A Comprehensive Histological Assessment of Osteoarthritis Lesions in Mice
Q57061220A Graphic User Interface for the Evaluation of Knee Osteoarthritis (GEKO): An open-source tool for histological grading
Q90322079A Mouse Noninvasive Intraarticular Tibial Plateau Compression Loading-Induced Injury Model of Posttraumatic Osteoarthritis
Q38831960A Surgical Model of Posttraumatic Osteoarthritis With Histological and Gait Validation
Q38812043A Three-Dimensional Chondrocyte-Macrophage Coculture System to Probe Inflammation in Experimental Osteoarthritis
Q92030363A bibliometric analysis of classic publications in web of science category of orthopedics
Q35167075A comparison between platelet-rich plasma (PRP) and hyaluronate acid on the healing of cartilage defects
Q24817024A monoclonal antibody against kininogen reduces inflammation in the HLA-B27 transgenic rat
Q42112997A novel in vivo murine model of cartilage regeneration. Age and strain-dependent outcome after joint surface injury
Q33319514A role for subchondral bone changes in the process of osteoarthritis; a micro-CT study of two canine models.
Q34122827A selective and potent CXCR3 antagonist SCH 546738 attenuates the development of autoimmune diseases and delays graft rejection.
Q99551349A serial multiparametric quantitative magnetic resonance imaging study to assess proteoglycan depletion of human articular cartilage and its effects on functionality
Q89619918AMD3100 Attenuates Post-Traumatic Osteoarthritis by Maintaining Transforming Growth Factor-β1-Induced Expression of Tissue Inhibitor of Metalloproteinase-3 via the Phosphatidylinositol 3-Kinase/Akt Pathway
Q24798273Acoustic stiffness and change in plug cartilage over time after autologous osteochondral grafting: correlation between ultrasound signal intensity and histological score in a rabbit model
Q35605695Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury
Q49293211Activation of a chondrocyte volume-sensitive Cl(-) conductance prior to macroscopic cartilage lesion formation in the rabbit knee anterior cruciate ligament transection osteoarthritis model
Q37092804Activation of beta-catenin signaling in articular chondrocytes leads to osteoarthritis-like phenotype in adult beta-catenin conditional activation mice.
Q42096174Activation of interleukin-1 signaling cascades in normal and osteoarthritic articular cartilage
Q33561132Activation of neutral metalloprotease in human osteoarthritic knee cartilage: evidence for degradation in the core protein of sulphated proteoglycan
Q90536765Activation of the leptin pathway by high expression of the long form of the leptin receptor (Ob-Rb) accelerates chondrocyte senescence in osteoarthritis
Q67763125Activity of anti-inflammatory drugs on an experimental model of osteoarthritis
Q41785351Acute joint pathology and synovial inflammation is associated with increased intra-articular fracture severity in the mouse knee
Q33807290Additive effects of intra-articular injection of growth hormone and hyaluronic acid in rabbit model of collagenase-induced osteoarthritis
Q42081641Age-related accumulation of pentosidine in aggrecan and collagen from normal and degenerate human intervertebral discs
Q37369629Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints
Q28509293Aging-related loss of the chromatin protein HMGB2 in articular cartilage is linked to reduced cellularity and osteoarthritis
Q42679493Aliskiren has chondroprotective efficacy in a rat model of osteoarthritis through suppression of the local renin-angiotensin system
Q43125645Alleviation of osteoarthritis by Trichostatin A, a histone deacetylase inhibitor, in experimental osteoarthritis
Q35381453Ameliorative effects of PACAP against cartilage degeneration. Morphological, immunohistochemical and biochemical evidence from in vivo and in vitro models of rat osteoarthritis
Q57643820Amyloid deposition in rheumatoid arthritis of the hip
Q40878851An assessment of the chondroprotective effects of intra-articular application of statin and tetracycline on early-stage experimental osteoarthritis
Q41935404An ex vivo model using human osteoarthritic cartilage demonstrates the release of bioactive insulin-like growth factor-1 from a collagen-glycosaminoglycan scaffold
Q34117139Angiogenesis and nerve growth factor at the osteochondral junction in rheumatoid arthritis and osteoarthritis.
Q28072990Animal models of osteoarthritis: classification, update, and measurement of outcomes
Q37450277Anti-apoptotic treatments prevent cartilage degradation after acute trauma to human ankle cartilage
Q44117274Anti-arthritic effects of crocin in interleukin-1β-treated articular chondrocytes and cartilage in a rabbit osteoarthritic model
Q37060577Anti-inflammatory effect of egg white-chalcanthite and purple bamboo salts mixture on arthritis induced by monosodium iodoacetate in Sprague-Dawley rats
Q41467346Appearance of calpain correlates with arthritis and cartilage destruction in collagen induced arthritic knee joints of mice
Q24805351Articular cartilage and changes in arthritis. An introduction: cell biology of osteoarthritis
Q34087323Articular cartilage and osteoarthrosis. The role of molecular markers to monitor breakdown, repair and disease.
Q77050437Articular cartilage lesions of the knee following immobilisation or destabilisation for 6 or 12 weeks in rabbits
Q33520991Articular cartilage mineralization in osteoarthritis of the hip.
Q35547831Articular cartilage superficial zone collagen birefringence reduced and cartilage thickness increased before surface fibrillation in experimental osteoarthritis
Q37439974Assessment of bone perfusion with contrast-enhanced magnetic resonance imaging.
Q43525281Assessment of safety and efficacy of methylsulfonylmethane on bone and knee joints in osteoarthritis animal model
Q24796118Autologous chondrocyte implantation for cartilage repair: monitoring its success by magnetic resonance imaging and histology
Q42049557Automated objective scoring of histologically apparent cartilage degeneration using a custom image analysis program.
Q33729300Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis
Q30317911BMP-2 shows characteristic extracellular patterns in osteoarthritic cartilage: a preliminary report
Q30401142Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1
Q39676689Benefits of recombinant adeno-associated virus (rAAV)-mediated insulinlike growth factor I (IGF-I) overexpression for the long-term reconstruction of human osteoarthritic cartilage by modulation of the IGF-I axis
Q43099829Bioactive IGF-1 release from collagen-GAG scaffold to enhance cartilage repair in vitro.
Q33551191Biochemical changes in progressive osteoarthrosis
Q39887108Biochemistry of articular cartilage. Nature of proteoglycans and collagen of articular cartilage and their role in ageing and in osteoarthrosis
Q34225355Biological aspects of early osteoarthritis
Q92063608Biomechanically, structurally and functionally meticulously tailored polycaprolactone/silk fibroin scaffold for meniscus regeneration
Q34008512Bullet-induced synovitis as a cause of secondary osteoarthritis of the hip joint: A case report and review of literature
Q34624759Bupivacaine and levobupivacaine induce apoptosis in rat chondrocyte cell cultures at ultra-low doses.
Q37291220CD8+ T cell-induced expression of tissue inhibitor of metalloproteinses-1 exacerbated osteoarthritis
Q91881530CORR Insights®: Do dGEMRIC and T2 Imaging Correlate With Histologic Cartilage Degeneration in an Experimental Ovine FAI Model?
Q37377108CXCL12/CXCR4 Axis Regulates Aggrecanase Activation and Cartilage Degradation in a Post-Traumatic Osteoarthritis Rat Model
Q37253924Calcification of human articular knee cartilage is primarily an effect of aging rather than osteoarthritis
Q67427626Calf anticular cartilage in organ culture in a chemically defined medium. I. Autoradiographic study after [35S]sulfate labeling
Q39746807Calf articular cartilage in organ culture in a chemically defined medium. 2. Concentrations of glycosaminoglycans and [35S]-sulfate incorporation at different oxygen tensions
Q43049901Carboxymethylated chitin reduces MMP-1 expression in rabbit ACLT osteoarthritic cartilage
Q73550780Carrageenan-induced arthritis in the rat
Q34542939Cartilage collagen damage in hip osteoarthritis similar to that seen in knee osteoarthritis; a case-control study of relationship between collagen, glycosaminoglycan and cartilage swelling
Q35847568Cartilage matrix changes in contralateral mobile knees in a rabbit model of osteoarthritis induced by immobilization
Q84890537Cartilage repair in the rabbit knee: mosaic plasty resulted in higher degree of tissue filling but affected subchondral bone more than microfracture technique: a blinded, randomized, controlled, long-term follow-up trial in 88 knees
Q42550148Cartilage-on-cartilage versus metal-on-cartilage impact characteristics and responses
Q24810433Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1 alpha in articular chondrocytes: involvement of HIF-1 alpha in the pathogenesis of osteoarthritis
Q33567207Cathepsin B in osteoarthritis: cytochemical and histochemical analysis of human femoral head cartilage
Q33567201Cathepsin B in osteoarthritis: zonal variation of enzyme activity in human femoral head cartilage
Q41846846Cationic agent contrast-enhanced computed tomography imaging of cartilage correlates with the compressive modulus and coefficient of friction
Q43152891Changes in Ultrastructure and Cytoskeletal Aspects of Human Normal and Osteoarthritic Chondrocytes Exposed to Interleukin-1β and Cyclical Hydrostatic Pressure
Q34570854Changes in articular cartilage after meniscectomy and meniscus replacement using a biodegradable porous polymer implant
Q35547004Changes in articular cartilage in experimentally induced patellar subluxation
Q33552008Changes with age in the glycosaminoglycans of human articular cartilage
Q42227385Characterisation of a divergent progenitor cell sub-populations in human osteoarthritic cartilage: the role of telomere erosion and replicative senescence
Q33553596Characterisation of human articular cartilage link proteins from normal and osteoarthritic cartilage
Q42557338Characterization of bone perfusion by dynamic contrast-enhanced magnetic resonance imaging and positron emission tomography in the Dunkin-Hartley guinea pig model of advanced osteoarthritis
Q55432542Characterizing human subchondral bone properties using near-infrared (NIR) spectroscopy.
Q49945925Chondral and osteochondral defects : Representation by imaging methods
Q34571485Chondrocalcinosis of femoro-tibial and proximal tibio-fibular joints in cadaveric specimens: a high-resolution CT imaging study of the calcification distribution
Q35679918Chondrocyte clusters adjacent to sites of cartilage degeneration have characteristics of progenitor cells.
Q36805504Chondrocyte moves: clever strategies?
Q47924979Chondrocyte phenotyping in human osteoarthritis
Q38526059Chondropenia: current concept review
Q41990316Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model.
Q36638569Circular RNA Related to the Chondrocyte ECM Regulates MMP13 Expression by Functioning as a MiR-136 'Sponge' in Human Cartilage Degradation
Q53077086Classification of histologically scored human knee osteochondral plugs by quantitative analysis of magnetic resonance images at 3T.
Q34275085Clinical optical coherence tomography of early articular cartilage degeneration in patients with degenerative meniscal tears
Q38895007Co-Expression and Co-Localization of Cartilage Glycoproteins CHI3L1 and Lubricin in Osteoarthritic Cartilage: Morphological, Immunohistochemical and Gene Expression Profiles
Q43081525Coenzyme Q10 ameliorates pain and cartilage degradation in a rat model of osteoarthritis by regulating nitric oxide and inflammatory cytokines
Q50052199Collagen Damage Location in Articular Cartilage Differs if Damage is Caused by Excessive Loading Magnitude or Rate
Q37043661Collagen synthesis in normal and osteoarthritic human cartilage
Q54484961Combination of MEK-ERK inhibitor and hyaluronic acid has a synergistic effect on anti-hypertrophic and pro-chondrogenic activities in osteoarthritis treatment.
Q42364352Combined detection of serum CTX-II and COMP concentrations in osteoarthritis model rabbits: an effective technique for early diagnosis and estimation of disease severity
Q64120795Combined surgery and chondrocyte cell-sheet transplantation improves clinical and structural outcomes in knee osteoarthritis
Q36871654Comparative analysis of gene expression profiles in normal hip human cartilage and cartilage from patients with necrosis of the femoral head
Q37506038Comparative digital cartilage histology for human and common osteoarthritis models
Q42722095Comparison of hip joint cartilage degeneration assessed by histology and ex vivo optical coherence tomography
Q35341533Comparison of microstructural and mechanical properties of trabeculae in femoral head from osteoporosis patients with and without cartilage lesions: a case-control study
Q35634428Comparison of various SYSADOA for the osteoarthritis treatment: an experimental study in rabbits
Q36578590Computer-aided preoperative planning in knee osteotomy
Q47650534Contrast-Enhanced Computed Tomography Enables Quantitative Evaluation of Tissue Properties at Intrajoint Regions in Cadaveric Knee Cartilage
Q34977987Contrast-Enhanced Nanofocus X-Ray Computed Tomography Allows Virtual Three-Dimensional Histopathology and Morphometric Analysis of Osteoarthritis in Small Animal Models.
Q36484996Contrast-enhanced CT with a high-affinity cationic contrast agent for imaging ex vivo bovine, intact ex vivo rabbit, and in vivo rabbit cartilage
Q35355105Correlation of dynamic impact testing, histopathology and visual macroscopic assessment in human osteoarthritic cartilage.
Q48324635Could Oxidative Stress Regulate the Expression of MicroRNA-146a and MicroRNA-34a in Human Osteoarthritic Chondrocyte Cultures?
Q36392167Crosstalk between FLS and chondrocytes is regulated by HIF-2α-mediated cytokines in arthritis
Q66849864Crystals and arthritis
Q41107189Curcumin-loaded poly lactic-co-glycolic acid nanoparticles effects on mono-iodoacetate -induced osteoarthritis in rats
Q34362994Cytokine profiles in the joint depend on pathology, but are different between synovial fluid, cartilage tissue and cultured chondrocytes
Q28512946Cytokine-like 1 knock-out mice (Cytl1-/-) show normal cartilage and bone development but exhibit augmented osteoarthritic cartilage destruction
Q35768757Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration
Q33843130Decrease in the expression of the type 1 PTH/PTHrP receptor (PTH1R) on chondrocytes in animals with osteoarthritis
Q21195655Decreased metalloproteinase production as a response to mechanical pressure in human cartilage: a mechanism for homeostatic regulation
Q42010980Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease-13: identification of a new biglycan cleavage site
Q64057317Detection of Early-Stage Degeneration in Human Articular Cartilage by Multiparametric MR Imaging Mapping of Tissue Functionality
Q47152090Development and Evaluation of Polyvinyl Alcohol-Hydrogels as an Artificial Atrticular Cartilage for Orthopedic Implants.
Q42768005Development of osteoarthritic lesions in mice by "metabolic" and "mechanical" alterations in the knee joints
Q36825856Development of partial-thickness articular cartilage injury in a rabbit model
Q69694008Development of post-traumatic arthrosis as in fractures of the tibial head
Q33728570Diagnostic performance of in vivo 3-T MRI for articular cartilage abnormalities in human osteoarthritic knees using histology as standard of reference
Q41862189Diet-induced obesity significantly increases the severity of posttraumatic arthritis in mice.
Q36999290Differences in Mammalian target of rapamycin gene expression in the peripheral blood and articular cartilages of osteoarthritic patients and disease activity
Q38974944Differences in type II collagen turnover of osteoarthritic human knee and ankle joints.
Q37642523Differential detection of type II collagen N-terminal and C-terminal denaturation epitopes in degrading cartilage
Q28193949Differential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro study
Q33346368Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.
Q72607275Differential histochemical staining of glycosaminoglycans in the matrix of osteoarthritic cartilage
Q37448639Differential metabolic effects of glucosamine and N-acetylglucosamine in human articular chondrocytes
Q33722208Does intraarticular inflammation predict biomechanical cartilage properties?
Q36151899Does metaphyseal cement augmentation in fracture management influence the adjacent subchondral bone and joint cartilage?: an in vivo study in sheep stifle joints.
Q33895200Downregulation of protein kinase CK2 activity facilitates tumor necrosis factor-α-mediated chondrocyte death through apoptosis and autophagy
Q37038055Drying of open animal joints in vivo subsequently causes cartilage degeneration.
Q37600074Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritis
Q50278125ENU-induced missense mutation in the C-propeptide coding region of Col2a1 creates a mouse model of platyspondylic lethal skeletal dysplasia, Torrance type
Q24799322Early and stable upregulation of collagen type II, collagen type I and YKL40 expression levels in cartilage during early experimental osteoarthritis occurs independent of joint location and histological grading
Q69960525Early changes in the ground substance of articular cartilage in experimental hemarthrosis in dogs, measured by the fixed-charge density method
Q52657612Early detection of osteoarthritis in rabbits using MRI with a double-contrast agent.
Q36943360Effect of Angelica sinensis Polysaccharides on Osteoarthritis In Vivo and In Vitro: A Possible Mechanism to Promote Proteoglycans Synthesis
Q87492026Effect of Ermiao Recipe with medicinal guide Angelicae Pubescentis Radix on promoting the homing of bone marrow stem cells to treat cartilage damage in osteoarthritis rats
Q33874274Effect of IL-1beta-induced macromolecular depletion on residual quadrupolar interaction in articular cartilage
Q72611603Effect of Mycoplasma arthritidis superantigen on enzymatically induced arthritis in mice
Q50271141Effect of advanced oxidation protein products on articular cartilage and synovium in a rabbit osteoarthritis model.
Q33569819Effect of anti-inflammatory drugs on sulphated glycosaminoglycan synthesis in aged human articular cartilage
Q30449888Effect of ascorbic acid on arylsulfatase activities and sulfated proteoglycan metabolism in chondrocyte cultures
Q79222791Effect of dehydroepiandrosterone on cartilage and synovium of knee joints with osteoarthritis in rabbits
Q34136135Effect of in utero exposure to diethylstilbestrol on lumbar and femoral bone, articular cartilage, and the intervertebral disc in male and female adult mice progeny with and without swimming exercise
Q37135322Effect of insulin-like growth factor-1 and hyaluronic acid in experimentally produced osteochondral defects in rats
Q41234544Effect of intra-articular corticosteroid injections on primate cartilage
Q44008317Effect of open wedge high tibial osteotomy on the lateral tibiofemoral compartment in sheep. Part II: standard and overcorrection do not cause articular cartilage degeneration
Q42024714Effect of passive motion on articular cartilage in rat osteoarthritis
Q39286500Effect of vitamins C and E on sulfated proteoglycan metabolism and sulfatase and phosphatase activities in organ cultures of human cartilage
Q64889934Effects of Controlling Abnormal Joint Movement on Expression of MMP13 and TIMP-1 in Osteoarthritis.
Q42393176Effects of adenovirus-mediated bFGF, IL-1Ra and IGF-1 gene transfer on human osteoarthritic chondrocytes and osteoarthritis in rabbits
Q41847330Effects of an aqueous extract of Eucommia on articular cartilage in a rat model of osteoarthritis of the knee
Q35681213Effects of diacerein on cartilage and subchondral bone in early stages of osteoarthritis in a rabbit model
Q35042960Effects of diclofenac, aceclofenac and meloxicam on the metabolism of proteoglycans and hyaluronan in osteoarthritic human cartilage
Q33622130Effects of glucosamine and risedronate alone or in combination in an experimental rabbit model of osteoarthritis
Q88393647Effects of knockout of the receptor for advanced glycation end-products on bone mineral density and synovitis in mice with intra-articular fractures
Q37419090Effects of mechanical stress on chondrocyte phenotype and chondrocyte extracellular matrix expression.
Q35547980Effects of methotrexate on normal articular cartilage in vitro and in vivo
Q35740945Effects of nicotine on a rat model of early stage osteoarthritis
Q35414105Effects of phosphorylatable short peptide-conjugated chitosan-mediated IL-1Ra and igf-1 gene transfer on articular cartilage defects in rabbits
Q90574368Effects of rAAV-Mediated sox9 Overexpression on the Biological Activities of Human Osteoarthritic Articular Chondrocytes in Their Intrinsic Three-Dimensional Environment
Q33882598Effects of surgically induced instability on rat knee articular cartilage.
Q42370869Effects of tenoxicam and aspirin on the metabolism of proteoglycans and hyaluronan in normal and osteoarthritic human articular cartilage
Q41473029Effects of transforming growth factor beta s and basic fibroblast growth factor on articular chondrocytes obtained from immobilised rabbit knees
Q30397658Effects of ultrasound on estradiol level, bone mineral density, bone biomechanics and matrix metalloproteinase-13 expression in ovariectomized rabbits
Q36641181Efficacy Evaluation of a New Hyaluronan Derivative HYADD(®) 4-G to Maintain Cartilage Integrity in a Rabbit Model of Osteoarthritis
Q61443756Efficacy and safety of culture-expanded, mesenchymal stem/stromal cells for the treatment of knee osteoarthritis: a systematic review protocol
Q41239589Efficacy of intra-articular injection of celecoxib in a rabbit model of osteoarthritis
Q33633097Emerging Roles of circRNA Related to the Mechanical Stress in Human Cartilage Degradation of Osteoarthritis
Q33513738Empirical evaluation of the inter-relationship of articular elements involved in the pathoanatomy of knee osteoarthritis using magnetic resonance imaging
Q35875201Endoplasmic reticulum stress induces the expression of COX-2 through activation of eIF2α, p38-MAPK and NF-κB in advanced glycation end products stimulated human chondrocytes.
Q24804001Endothelin-1 in osteoarthritic chondrocytes triggers nitric oxide production and upregulates collagenase production
Q54615289Enhanced apoptotic and reduced protective response in chondrocytes following endoplasmic reticulum stress in osteoarthritic cartilage.
Q37365557Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage
Q37562358Enhanced expression of the central survival of motor neuron (SMN) protein during the pathogenesis of osteoarthritis
Q42585391Enhanced extractability of articular cartilage protoglycans in osteoarthrosis
Q35287635Estrogens antagonize RUNX2-mediated osteoblast-driven osteoclastogenesis through regulating RANKL membrane association
Q41899806Etanercept enhances preservation of osteochondral allograft viability
Q35665907Eupatilin Exerts Antinociceptive and Chondroprotective Properties in a Rat Model of Osteoarthritis by Downregulating Oxidative Damage and Catabolic Activity in Chondrocytes
Q34978060Evaluating Osteoarthritic Chondrocytes through a Novel 3-Dimensional In Vitro System for Cartilage Tissue Engineering and Regeneration
Q43292144Evaluation of Single-Impact-Induced Cartilage Degeneration by Optical Coherence Tomography
Q37251575Evaluation of cartilage degeneration in a rat model of rotator cuff tear arthropathy
Q53173966Evaluation of osteoarthritis induced by treadmill-running exercise using the modified Mankin and the new OARSI assessment system.
Q47815078Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus
Q37388249Evidence for altered synthesis of type II collagen in patients with osteoarthritis
Q33848759Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage
Q45975039Examination of osteoarthritis and subchondral bone alterations within the stifle joint of an ovariectomised ovine model.
Q41834432Experimental joint immobilization and remobilization in the rats
Q35750612Expression and pathological effects of periostin in human osteoarthritis cartilage
Q39114446Expression of CHI3L1 and CHIT1 in osteoarthritic rat cartilage model. A morphological study.
Q38634266Expression of Cannabinoid Receptors in Human Osteoarthritic Cartilage: Implications for Future Therapies
Q24657447Expression of MicroRNA-146a in osteoarthritis cartilage
Q24675261Expression of alpha and beta subunits of the integrin superfamily in articular cartilage from macroscopically normal and osteoarthritic human femoral heads
Q54705356Expression of collagen type I and type II in consecutive stages of human osteoarthritis.
Q24670233Expression of early and late differentiation markers (proliferating cell nuclear antigen, syndecan-3, annexin VI, and alkaline phosphatase) by human osteoarthritic chondrocytes
Q42049394Expression of membrane-type 1 matrix metalloproteinase and activation of progelatinase A in human osteoarthritic cartilage.
Q52950155Expression of the VEGF receptor-3 in osteoarthritic chondrocytes: stimulation by interleukin-1 beta and association with beta 1-integrins.
Q35636643Expression of the matrix receptor CD44v5 on chondrocytes changes with osteoarthritis: an experimental investigation in the rabbit
Q35549333Expression of thrombospondin-1 and its receptor CD36 in human osteoarthritic cartilage
Q74506491Expression of transforming growth factor-beta isoforms and their receptors in chronic tendinosis
Q35015174Expression of vascular endothelial growth factor on chondrocytes increases with osteoarthritis - an animal experimental investigation
Q39712435Expression of β-defensin-4 in "an in vivo and ex vivo model" of human osteoarthritic knee meniscus
Q35769105Extracellular localization of galectin-3 has a deleterious role in joint tissues
Q46044165Extracorporeal Shockwave Therapy Enhances Expression of Pdia-3 Which Is a Key Factor of the 1α,25-Dihydroxyvitamin D 3 Rapid Membrane Signaling Pathway in Treatment of Early Osteoarthritis of the Knee
Q33892796Extracorporeal shockwave therapy in osteoporotic osteoarthritis of the knee in rats: an experiment in animals.
Q34565263Extracorporeal shockwave therapy shows a number of treatment related chondroprotective effect in osteoarthritis of the knee in rats
Q35901765Extrusion of pyrophosphate into extracellular media by osteoarthritic cartilage incubates
Q37140573FREQUENCY CONTENT OF CARTILAGE IMPACT FORCE SIGNAL REFLECTS ACUTE HISTOLOGIC STRUCTURAL DAMAGE.
Q83185496Failed cartilage repair for early osteoarthritis defects: a biochemical, histological and immunohistochemical analysis of the repair tissue after treatment with marrow-stimulation techniques
Q49804388Fib3-3 as a Biomarker for Osteoarthritis in a Rat Model with Metabolic Dysregulation
Q41677568Fluoxetine ameliorates cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling
Q38645334Focal Defects of the Knee Articular Surface: Evidence of a Regenerative Potential Pattern in Osteochondritis Dissecans and Degenerative Lesions.
Q35547407Gene expression of matrix metalloproteinases 1, 3, and 9 by chondrocytes in osteoarthritic human knee articular cartilage is zone and grade specific
Q33940184Genes involved in the osteoarthritis process identified through genome wide expression analysis in articular cartilage; the RAAK study.
Q38865265Ginsenoside Rb1 inhibits matrix metalloproteinase 13 through down-regulating Notch signaling pathway in osteoarthritis
Q37690232Glycophenotyping of osteoarthritic cartilage and chondrocytes by RT-qPCR, mass spectrometry, histochemistry with plant/human lectins and lectin localization with a glycoprotein
Q39329264Grape seed proanthocyanidin extract ameliorates monosodium iodoacetate-induced osteoarthritis
Q37270775Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-alpha and matrix metalloproteinase-13 in human chondrocytes
Q55472630Guava leaf extract suppresses osteoarthritis progression in a rat anterior cruciate ligament transection model.
Q37627264High density micromass cultures of a human chondrocyte cell line: a reliable assay system to reveal the modulatory functions of pharmacological agents.
Q47366472High occurrence of osteoarthritic histopathological features unaccounted for by traditional scoring systems in lateral femoral condyles from total knee arthroplasty patients with varus alignment.
Q55374681High-fat/high-sucrose diet-induced obesity results in joint-specific development of osteoarthritis-like degeneration in a rat model.
Q34753538Histological and molecular characterisation of feline humeral condylar osteoarthritis.
Q71567523Histological comparison of patellar cartilage degeneration between chondromalacia in youth and osteoarthritis in aging
Q67577499Histological examination of surface repair tissue after successful osteotomy for osteoarthritis of the hip joint
Q34990940Histone deacetylase 4 alters cartilage homeostasis in human osteoarthritis
Q42245886Histopathology of naturally occurring and surgically induced osteoarthritis in mice
Q35597515Homing and reparative effect of intra-articular injection of autologus mesenchymal stem cells in osteoarthritic animal model.
Q64929160Human amniotic membrane intra-articular injection prevents cartilage damage in an osteoarthritis model.
Q67651165Human joint capsule in osteoarthrosis (morpholocical changes) (author's transl)
Q30558532Human osteoarthritic chondrocytes exposed to extremely low-frequency electromagnetic fields (ELF) and therapeutic application of musically modulated electromagnetic fields (TAMMEF) systems: a comparative study.
Q57901365Human osteoarthritic knee cartilage: fingerprinting of adhesion/growth-regulatory galectins in vitro and in situ indicates differential upregulation in severe degeneration
Q36485598Hyaluronan concentration and size distribution in human knee synovial fluid: variations with age and cartilage degeneration.
Q42323209Hydrostatic Pressure Regulates MicroRNA Expression Levels in Osteoarthritic Chondrocyte Cultures via the Wnt/β-Catenin Pathway
Q42134204Hypoxia and HIF-1alpha in osteoarthritis.
Q84285592Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction
Q35754688Hypoxia-inducible factor-2α regulates Fas-mediated chondrocyte apoptosis during osteoarthritic cartilage destruction
Q34742553IL-1beta regulates FHL2 and other cytoskeleton-related genes in human chondrocytes
Q89338763IL-1β Enhances Wnt Signal by Inhibiting DKK1
Q30439206IL-6 receptor antagonist as adjunctive therapy with clotting factor replacement to protect against bleeding-induced arthropathy in hemophilia
Q91999266Imaging of proteoglycan and water contents in human articular cartilage with full-body CT using dual contrast technique
Q41548335Immunogenicity of xenogeneic cartilage matrix components in a rabbit model
Q79294908Immunohistochemical analysis of transforming growth factor beta isoforms and their receptors in human cartilage from normal and osteoarthritic femoral heads
Q38319778Immunohistochemical localization of articular cartilage proteoglycan and link protein in situ using monoclonal antibodies and lectin-binding methods
Q37104061Impact of lesion location on the progression of osteoarthritis in a rat knee model
Q35819669Impact of storage conditions on electromechanical, histological and histochemical properties of osteochondral allografts
Q24678462Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase
Q67929038In vitro influence of ketoprofen on the proteoglycan metabolism of human normal and osteoarthritis cartilage
Q43145683In vivo effects of single intra-articular injection of 0.5% bupivacaine on articular cartilage.
Q36322875In vivo performance of a novel silk fibroin scaffold for partial meniscal replacement in a sheep model
Q40814456In vivo transfer of interleukin-1 receptor antagonist gene in osteoarthritic rabbit knee joints: prevention of osteoarthritis progression
Q43049177Increased Bcl-2/p53 ratio in human osteoarthritic cartilage: a possible role in regulation of chondrocyte metabolism
Q40840813Increased Production of Clusterin in Biopsies of Repair Tissue following Autologous Chondrocyte Implantation
Q34140878Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay
Q45070229Indentation mapping revealed poroelastic, but not viscoelastic, properties spanning native zonal articular cartilage
Q33892588Independent expression of fibril-forming collagens I, II, and III in chondrocytes of human osteoarthritic cartilage
Q37085644Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice.
Q36878348Inflammatory markers associated with osteoarthritis after destabilization surgery in young mice with and without Receptor for Advanced Glycation End-products (RAGE)
Q44832606Influence of irrigation solutions combined with colchicine and diclofenac sodium on articular cartilage in a rat model
Q44487664Influence of superoxide dismutase on staphylococcal arthritis--a histological and biochemical investigation using an experimental animal model
Q34533294Infrared fiber optic probe evaluation of degenerative cartilage correlates to histological grading
Q34718185Instability dependency of osteoarthritis development in a rabbit model of graded anterior cruciate ligament transection.
Q36625624Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) is closely associated with the chondrocyte nucleus in human articular cartilage.
Q34077618Integrating carthage-specific T1rho MRI into knee clinic diagnostic imaging
Q38615243Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis.
Q64083778Interleukin-1 receptor antagonist protein (IL-1Ra) and miR-140 overexpression via pNNS-conjugated chitosan-mediated gene transfer enhances the repair of full-thickness cartilage defects in a rabbit model
Q41320421Interleukin-17 Can Induce Osteoarthritis in Rabbit Knee Joints Similar to Hulth's Method.
Q34991513International Cartilage Repair Society (ICRS) Recommended Guidelines for Histological Endpoints for Cartilage Repair Studies in Animal Models and Clinical Trials
Q36055278Interruption of glycosphingolipid synthesis enhances osteoarthritis development in mice
Q50457921Intra- and inter-observer reliability of ten major histological scoring systems used for the evaluation of in vivo cartilage repair.
Q59812517Intra-Articular Injection of Extract Attenuates Pain Behavior and Cartilage Degeneration in Mono-Iodoacetate Induced Osteoarthritic Rats
Q35173708Intra-articular hyaluronate, tenoxicam and vitamin E in a rat model of osteoarthritis: evaluation and comparison of chondroprotective efficacy
Q42273139Intra-articular injection of Torin 1 reduces degeneration of articular cartilage in a rabbit osteoarthritis model
Q35769067Intra-articular injection of a nutritive mixture solution protects articular cartilage from osteoarthritic progression induced by anterior cruciate ligament transection in mature rabbits: a randomized controlled trial
Q35963128Intra-articular injection of mono-iodoacetate induces osteoarthritis of the hip in rats
Q42135407Intra-articular injection of synthetic microRNA-210 accelerates avascular meniscal healing in rat medial meniscal injured model.
Q68192056Intra-articular injections and articular cartilage metabolism. An experimental study in rabbits
Q87511725Intra-articular zoledronic acid in a rat osteoarthritis model: significant reduced synovitis may indicate chondroprotective effect
Q84145682Investigating the potential value of individual parameters of histological grading systems in a sheep model of cartilage damage: the Modified Mankin method
Q58700385Investigation of Lake Hévíz Mineral Water Balneotherapy and Hévíz Mud Treatment in Murine Osteoarthritis and Rheumatoid Arthritis Models
Q37366774Investigation of the frictional response of osteoarthritic human tibiofemoral joints and the potential beneficial tribological effect of healthy synovial fluid
Q37168538Involution of collagen-induced arthritis with an angiogenesis inhibitor, PPI-2458.
Q30317619Is there a correlation between biophotonical, biochemical, histological, and visual changes in the cartilage of osteoarthritic knee-joints?
Q36931350Ketamine attenuates osteoarthritis of the knee via modulation of inflammatory responses in a rabbit model
Q95643019Knee muscle atrophy is a risk factor for development of knee osteoarthritis in a rat model
Q99579436L-Carnitine potentiates the anti-inflammatory and antinociceptive effects of diclofenac sodium in an experimentally-induced knee osteoarthritis rat model
Q38806224Lactoferrin from Camelus dromedarius Inhibits Nuclear Transcription Factor-kappa B Activation, Cyclooxygenase-2 Expression and Prostaglandin E2 Production in Stimulated Human Chondrocytes
Q37208260Lentiviral small hairpin RNA knockdown of macrophage inflammatory protein-1γ ameliorates experimentally induced osteoarthritis in mice
Q70397168Limitations of safranin 'O' staining in proteoglycan-depleted cartilage demonstrated with monoclonal antibodies
Q64905780Local Effects Following Single and Repeat Intra-Articular Injections of Triamcinolone Acetonide Extended-Release: Results from Three Nonclinical Toxicity Studies in Dogs.
Q35831770Local changes in proteoglycan synthesis during culture are different for normal and osteoarthritic cartilage.
Q89811011Local transplantation of adipose-derived stem cells has a significant therapeutic effect in a mouse model of rheumatoid arthritis
Q84778740Localization of degenerative changes of the acromioclavicular joint: a cadaveric study
Q37690622Low-density lipoprotein receptor-related protein 5 governs Wnt-mediated osteoarthritic cartilage destruction
Q35555022Macroscopic and histopathologic analysis of human knee menisci in aging and osteoarthritis.
Q39707568Macroscopic and radiological grading of osteoarthritis correlates inadequately with cartilage height and histologically demonstrable damage to cartilage structure
Q36867813Macroscopical, Histological, and In Vitro Characterization of Nonosteoarthritic Versus Osteoarthritic Hip Joint Cartilage
Q49024985Magnetic resonance imaging and histology of ovine hip joint cartilage in two age populations: a sheep model with assumed healthy cartilage
Q33856601Mechanical loading of in situ chondrocytes in lapine retropatellar cartilage after anterior cruciate ligament transection
Q59813119Mechanism research on a bioactive resveratrol- PLA-gelatin porous nano-scaffold in promoting the repair of cartilage defect
Q44593204Mechanisms of sodium nitroprusside-induced death in human chondrocytes
Q46588283Metabolic regulatory and anti-oxidative effects of modified Bushen Huoxue decoction on experimental rabbit model of osteoarthritis
Q33553359Metabolic responses of cartilage in experimentally induced osteoarthritis
Q33552817Metabolism of human femoral head cartilage in osteoarthrosis and subcapital fracture
Q64103091Mianserin suppresses R-spondin 2-induced activation of Wnt/β-catenin signaling in chondrocytes and prevents cartilage degradation in a rat model of osteoarthritis
Q64062306MicroRNA-26a reduces synovial inflammation and cartilage injury in osteoarthritis of knee joints through impairing the NF-κB signaling pathway
Q36983759MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis
Q92571570MicroRNA-34a and MicroRNA-181a Mediate Visfatin-Induced Apoptosis and Oxidative Stress via NF-κB Pathway in Human Osteoarthritic Chondrocytes
Q40967339Microarray study of gene expression profile to identify new candidate genes involved in the molecular mechanism of leptin-induced knee joint osteoarthritis in rat
Q36934980Microstructural remodeling of articular cartilage following defect repair by osteochondral autograft transfer
Q34501696Mild degenerative changes of hip cartilage in elderly patients: an available sample representative of early osteoarthritis
Q98159630Miniaturized Water-Jet Ultrasound Indentation System for Quantitative Assessment of Articular Cartilage Degeneration: A Validation Study
Q33865954Modification of osteoarthritis in the guinea pig with pulsed low-intensity ultrasound treatment
Q41127191Monitoring osteoarthritis progression using near infrared (NIR) spectroscopy.
Q42679586Mori Folium water extract alleviates articular cartilage damages and inflammatory responses in monosodium iodoacetate‑induced osteoarthritis rats
Q61806935Moxibustion of Zusanli (ST36) and Shenshu (BL23) Alleviates Cartilage Degradation through RANKL/OPG Signaling in a Rabbit Model of Rheumatoid Arthritis
Q36994935Multi-parametric MRI characterization of enzymatically degraded articular cartilage
Q30455418Multimodal evaluation of tissue-engineered cartilage
Q55037851Multiparametric MRI and Computational Modelling in the Assessment of Human Articular Cartilage Properties: A Comprehensive Approach.
Q34783518Multiparametric and semiquantitative scoring systems for the evaluation of mouse model histopathology--a systematic review
Q35405312Myrtol ameliorates cartilage lesions in an osteoarthritis rat model
Q40718621NELL-1 promotes cartilage regeneration in an in vivo rabbit model
Q64064105NNS-Conjugated Chitosan Mediated IGF-1 and miR-140 Overexpression in Articular Chondrocytes Improves Cartilage Repair
Q49909377Non-canonical Wnt induces chondrocyte de-differentiation through Frizzled 6 and DVL-2/B-raf/CaMKIIα/syndecan 4 axis
Q28076979Nutraceutical Supplements in the Management and Prevention of Osteoarthritis
Q37028971Nutrition and degeneration of articular cartilage
Q28486333Of mice, men and elephants: the relation between articular cartilage thickness and body mass
Q34255749Optical Coherence Tomography Detection of Subclinical Traumatic Cartilage Injury
Q30365831Optical coherence tomography enables accurate measurement of equine cartilage thickness for determination of speed of sound.
Q50197504Optical coherence tomography grading correlates with MRI T2 mapping and extracellular matrix content
Q35861310Optical coherence tomography-based parameterization and quantification of articular cartilage surface integrity
Q30475527Optical spectral reflectance of human articular cartilage - relationships with tissue structure, composition and mechanical properties
Q37071636Optimized extraction of glycosaminoglycans from normal and osteoarthritic cartilage for glycomics profiling
Q30384235Oral Resveratrol Prevents Osteoarthritis Progression in C57BL/6J Mice Fed a High-Fat Diet
Q91855023Oral administration of N-acetyl cysteine prevents osteoarthritis development and progression in a rat model
Q67600078Organ culture of human articular cartilage: studies on sulphated glycosaminoglycan synthesis
Q43107286Organ‐level histological and biomechanical responses from localized osteoarticular injury in the rabbit knee
Q36184418Osteoarthritis in the Knee Joints of Göttingen Minipigs after Resection of the Anterior Cruciate Ligament? Missing Correlation of MRI, Gene and Protein Expression with Histological Scoring
Q55512084Osteoarthritis-Like Changes in Bardet-Biedl Syndrome Mutant Ciliopathy Mice (Bbs1M390R/M390R): Evidence for a Role of Primary Cilia in Cartilage Homeostasis and Regulation of Inflammation.
Q53992300Osteoarthritis: Joint instability and OA: do animal models provide insights?
Q37682714Osteoarthritis: can anti-cytokine therapy play a role in treatment?
Q38069484Osteoarthritis: histology and pathogenesis
Q33882628Osteochondral angiogenesis and increased protease inhibitor expression in OA.
Q42751154Osteoprotegerin reduces the development of pain behaviour and joint pathology in a model of osteoarthritis
Q35103192Overexpression of human matrix metalloproteinase-12 enhances the development of inflammatory arthritis in transgenic rabbits
Q35586509Pathology of the calcified zone of articular cartilage in post-traumatic osteoarthritis in rat knees
Q37213147Performance of a sterile meniscal allograft in an ovine model
Q35828443Phenotypic characterization of osteoarthritic osteocytes from the sclerotic zones: a possible pathological role in subchondral bone sclerosis.
Q35547255Phenotypic modulation of chondrocytes as a potential therapeutic target in osteoarthritis: a hypothesis
Q44557093Phosphorylation of osteopontin in osteoarthritis degenerative cartilage and its effect on matrix metalloprotease 13.
Q42955838Pigment epithelium derived factor--the product of the EPC-1 gene--is expressed by articular chondrocytes and up regulated in osteoarthritis.
Q30235227Plausible Roles for RAGE in Conditions Exacerbated by Direct and Indirect (Secondhand) Smoke Exposure
Q91674148Polarized reflectance from articular cartilage depends upon superficial zone collagen network microstructure
Q41662003Polyvinyl alcohol hydrogel irradiated and acetalized for osteochondral defect repair: mechanical, chemical, and histological evaluation after implantation in rat knees
Q34346400Pomegranate extract inhibits the interleukin-1β-induced activation of MKK-3, p38α-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes.
Q38986426Post-traumatic osteoarthritis of the ankle: A distinct clinical entity requiring new research approaches
Q39904130Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice
Q24804197Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function
Q37351354Preclinical evaluation of a novel implant for treatment of a full-thickness distal femoral focal cartilage defect
Q41253489Preliminary observations of chondral abrasion in a canine model
Q34087316Problems and paradigms in joint pathology
Q28729755Procyanidin B3 prevents articular cartilage degeneration and heterotopic cartilage formation in a mouse surgical osteoarthritis model
Q64913447Progression of Post-Traumatic Osteoarthritis in rat meniscectomy models: Comprehensive monitoring using MRI.
Q24816732Proliferation and differentiation potential of chondrocytes from osteoarthritic patients
Q34154175Proliferative remodeling of the spatial organization of human superficial chondrocytes distant from focal early osteoarthritis
Q35840732Prostaglandin E2 receptor type 2-selective agonist prevents the degeneration of articular cartilage in rabbit knees with traumatic instability
Q33744824Protective effect of Shenmai injection on knee articular cartilage of osteoarthritic rabbits and IL-1β-stimulated human chondrocytes
Q92717181Protective effect of glucosamine and risedronate (alone or in combination) against osteoarthritic changes in rat experimental model of immobilized knee
Q64123739Protective effect of prebiotic and exercise intervention on knee health in a rat model of diet-induced obesity
Q47145743Protective effect of zoledronic acid on articular cartilage and subchondral bone of rabbits with experimental knee osteoarthritis
Q34610146Protective effects of biochanin A on articular cartilage: in vitro and in vivo studies
Q36196730Protective effects of tumor necrosis factor-α blockade by adalimumab on articular cartilage and subchondral bone in a rat model of osteoarthritis
Q41167677Proteoglycan synthesis and osteophyte formation in 'metabolically' and 'mechanically' induced murine degenerative joint disease: an in-vivo autoradiographic study
Q34302667Proteoglycans of cartilage
Q34581643Proteomic analysis of rat cartilage: the identification of differentially expressed proteins in the early stages of osteoarthritis
Q94452622Protocol for Harvest, Transport and Storage of Human Osteochondral Tissue
Q71283549Quantification of morphometric changes in murine experimental osteoarthritis using image analysis
Q64063721Quantifying Complex Micro-Topography of Degenerated Articular Cartilage Surface by Contrast-Enhanced Micro-Computed Tomography and Parametric Analyses
Q55075753Quantifying the Effects of Different Treadmill Training Speeds and Durations on the Health of Rat Knee Joints.
Q28386961Quantitative MRI using T1ρ and T2 in human osteoarthritic cartilage specimens: correlation with biochemical measurements and histology
Q40091046Quantitative OCT and MRI biomarkers for the differentiation of cartilage degeneration
Q37364390Quantitative proteomics reveals regulatory differences in the chondrocyte secretome from human medial and lateral femoral condyles in osteoarthritic patients
Q40792334RECK is up-regulated and involved in chondrocyte cloning in human osteoarthritic cartilage
Q36403164Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage
Q30931885Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes
Q24671477Regulation of type II collagen synthesis during osteoarthritis by prolyl-4-hydroxylases: possible influence of low oxygen levels
Q44606527Remodelling of human osteoarthritic cartilage by FGF-2, alone or combined with Sox9 via rAAV gene transfer
Q24803700Repression of anti-proliferative factor Tob1 in osteoarthritic cartilage
Q34229058Reproducibility of sodium MRI measures of articular cartilage of the knee in osteoarthritis
Q43522419Role of Fibulin 3 in Aging-Related Joint Changes and Osteoarthritis Pathogenesis in Human and Mouse Knee Cartilage
Q34565410SOX11 contributes to the regulation of GDF5 in joint maintenance
Q36466909Safety and biodistribution assessment of sc-rAAV2.5IL-1Ra administered via intra-articular injection in a mono-iodoacetate-induced osteoarthritis rat model
Q34119782Sanmiao formula inhibits chondrocyte apoptosis and cartilage matrix degradation in a rat model of osteoarthritis
Q33667186Schisandrae Fructus ethanol extract ameliorates inflammatory responses and articular cartilage damage in monosodium iodoacetate-induced osteoarthritis in rats
Q35632005Sclareol exerts anti-osteoarthritic activities in interleukin-1β-induced rabbit chondrocytes and a rabbit osteoarthritis model.
Q40715004Section of the anterior cruciate ligament in the rabbit as animal model for osteoarthritis progression
Q35034750Sequential change in T2* values of cartilage, meniscus, and subchondral bone marrow in a rat model of knee osteoarthritis
Q38274507Serum keratan sulfate transiently increases in the early stage of osteoarthritis during strenuous running of rats: protective effect of intraarticular hyaluronan injection.
Q64227250Shexiang-Wulong Pills Attenuate Rheumatoid Arthritis by Alleviating Inflammation in a Mouse Model of Collagen-Induced Arthritis
Q47699192Shortwave-infrared Raman spectroscopic classification of water fractions in articular cartilage ex vivo
Q38833484Shoulder arthritis secondary to rotator cuff tear: A reproducible murine model and histopathologic scoring system
Q36757016Silencing of miR-101 Prevents Cartilage Degradation by Regulating Extracellular Matrix-related Genes in a Rat Model of Osteoarthritis.
Q55290429Site-specific glycosaminoglycan content is better maintained in the pericellular matrix than the extracellular matrix in early post-traumatic osteoarthritis.
Q28508457Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen
Q30450699SnoN suppresses maturation of chondrocytes by mediating signal cross-talk between transforming growth factor-β and bone morphogenetic protein pathways
Q46890543Sorbitol-modified hyaluronic acid reduces oxidative stress, apoptosis and mediators of inflammation and catabolism in human osteoarthritic chondrocytes
Q42108394Spectrocolorimetric assessment of cartilage plugs after autologous osteochondral grafting: correlations between color indices and histological findings in a rabbit model
Q36067671State-of-the-art disease-modifying osteoarthritis drugs
Q34554322Statin prevents chondrocyte aging and degeneration of articular cartilage in osteoarthritis (OA).
Q34383424Statistical shape modeling describes variation in tibia and femur surface geometry between Control and Incidence groups from the osteoarthritis initiative database
Q34415023Stem Cells and Cartilage Development: Complexities of a Simple Tissue
Q35023177Structural associations of symptomatic knee osteoarthritis
Q36767844Structure-function relationships in osteoarthritic human hip joint articular cartilage
Q35613010Studies of the articular cartilage proteoglycan aggrecan in health and osteoarthritis. Evidence for molecular heterogeneity and extensive molecular changes in disease
Q68636715Study of the effect of a glycosaminoglycan-peptide complex on the degradative enzyme activities in human osteoarthritic cartilage
Q36314741Subchondral bone histology and grading in osteoarthritis
Q34153080Subchondral bone microstructural damage by increased remodelling aggravates experimental osteoarthritis preceded by osteoporosis
Q42733520Subchondral fluid dynamics in a model of osteoarthritis: use of dynamic contrast-enhanced magnetic resonance imaging
Q48291241Subchondral screw abutment: does it harm the joint cartilage? An in vivo study on sheep tibiae
Q46485316Sucrose, But Not Glucose, Blocks IL1-β-Induced Inflammatory Response in Human Chondrocytes by Inducing Autophagy via AKT/mTOR Pathway
Q33570111Sulphated glycosaminoglycan synthesis in normal and osteoarthrotic hip cartilage
Q39674514Superficial collagen fibril modulus and pericellular fixed charge density modulate chondrocyte volumetric behaviour in early osteoarthritis.
Q90175715Synchrotron MicroCT Reveals the Potential of the Dual Contrast Technique for Quantitative Assessment of Human Articular Cartilage Composition
Q34997730Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis
Q41169866Synovial mesenchymal stem cells promote meniscus regeneration augmented by an autologous Achilles tendon graft in a rat partial meniscus defect model
Q34572095Synoviocytes protect cartilage from the effects of injury in vitro
Q42409487T1ρ and T2 relaxation times are associated with progression of hip osteoarthritis.
Q38197117T2* mapping for articular cartilage assessment: principles, current applications, and future prospects.
Q35154087T2* measurement of the knee articular cartilage in osteoarthritis at 3T.
Q41808085Targeted transplantation of iron oxide-labeled, adipose-derived mesenchymal stem cells in promoting meniscus regeneration following a rabbit massive meniscal defect
Q50045905Targeting mitochondrial responses to intra-articular fracture to prevent posttraumatic osteoarthritis.
Q33875225Temporary immobilisation facilitates repair of chemically induced articular cartilage injury.
Q43049927Tenascin and aggrecan expression by articular chondrocytes is influenced by interleukin 1beta: a possible explanation for the changes in matrix synthesis during osteoarthritis
Q50015460Tenascin-C Prevents Articular Cartilage Degeneration in Murine Osteoarthritis Models.
Q89746459Tenascin-C expression controls the maturation of articular cartilage in mice
Q34476177Terahertz pulsed imaging of knee cartilage
Q21195261The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells
Q42948834The DNA repair enzyme apurinic/apyrimidinic endonuclease (Apex nuclease) 2 has the potential to protect against down-regulation of chondrocyte activity in osteoarthritis
Q37134372The NAD-Dependent Deacetylase Sirtuin-1 Regulates the Expression of Osteogenic Transcriptional Activator Runt-Related Transcription Factor 2 (Runx2) and Production of Matrix Metalloproteinase (MMP)-13 in Chondrocytes in Osteoarthritis
Q34168273The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the guinea pig
Q91928121The Preventive Effects of Greenshell Mussel (Perna canaliculus) on Early-Stage Metabolic Osteoarthritis in Rats with Diet-Induced Obesity
Q41115246The Preventive Effects of Nanopowdered Peanut Sprout-added Caciocavallo Cheese on Collagen-induced Arthritic Mice
Q55383886The Radiated Deep-frozen Xenogenic Meniscal Tissue Regenerated the Total Meniscus with Chondroprotection.
Q36707948The Relationship between HIF-2α and VEGF with Radiographic Severity in the Primary Osteoarthritic Knee
Q37418494The TMSB4 Pseudogene LncRNA Functions as a Competing Endogenous RNA to Promote Cartilage Degradation in Human Osteoarthritis.
Q36599350The application of optical coherence tomography in musculoskeletal disease
Q47641365The association between parathyroid hormone 1‑34 and the Wnt/β‑catenin signaling pathway in a rat model of osteoarthritis
Q28546516The biomarkers changes in serum and the correlation with quantitative MRI markers by histopathologic evaluation of the cartilage in surgically-induced osteoarthritis rabbit model
Q52644127The bovine patella as a model of early osteoarthritis.
Q57214164The challenge of implant integration in partial meniscal replacement: an experimental study on a silk fibroin scaffold in sheep
Q85623878The chemokine CCL20 induces proinflammatory and matrix degradative responses in cartilage
Q35902960The chondroprotective effects of intraarticular application of statin in osteoarthritis: An experimental study
Q30401702The contribution of bone and cartilage to the near-infrared spectrum of osteochondral tissue
Q40300560The deposition of immunoglobulins and complement in osteoarthritic cartilage
Q35728563The disease-modifying effect of dehydroepiandrosterone in different stages of experimentally induced osteoarthritis: a histomorphometric study
Q36084922The distribution pattern of critically short telomeres in human osteoarthritic knees
Q84866039The effect of different treatment time of millimeter wave on chondrocyte apoptosis, caspase-3, caspase-8, and MMP-13 expression in rabbit surgically induced model of knee osteoarthritis
Q71345679The effects of ciprofloxacin on human chondrocytes in cell culture
Q41764301The effects of intra-articular platelet-rich plasma injection according to the severity of collagenase-induced knee osteoarthritis in a rabbit model
Q45059189The effects of physical activity on apoptosis and lubricin expression in articular cartilage in rats with glucocorticoid-induced osteoporosis
Q80463747The efficacy of Brazilian black mud treatment in chronic experimental arthritis
Q31955662The fate of the articular cartilage in intracapsular fracture of the femoral neck (articular cartilage in femoral neck fracture).
Q33667432The influence of long-term treadmill exercise on bone mass and articular cartilage in ovariectomized rats
Q47381347The interrelation of osteoarthritis and diabetes mellitus: considering the potential role of interleukin-10 and in vitro models for further analysis.
Q33951067The oncofetal gene survivin is re-expressed in osteoarthritis and is required for chondrocyte proliferation in vitro
Q24812406The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanases.
Q34334367The quantitative and functional relation between insulin-like growth factor-I (IGF) and IGF-binding proteins during human osteoarthritis
Q43048764The regulation of human MMP-13 by licofelone, an inhibitor of cyclo-oxygenases and 5-lipoxygenase, in human osteoarthritic chondrocytes is mediated by the inhibition of the p38 MAP kinase signalling pathway
Q92828667The role of intra-articular administration of Fetuin-A in post-traumatic knee osteoarthritis: an experimental study in a rat model
Q39738345The role of prostaglandin E2 receptors in the pathogenesis of rheumatoid arthritis
Q41959456The role of stem cells in osteoarthritis: An experimental study in rabbits.
Q24816543The utility of pathway selective estrogen receptor ligands that inhibit nuclear factor-kappa B transcriptional activity in models of rheumatoid arthritis
Q42121040Theranostic immunoliposomes for osteoarthritis
Q49575147Therapeutic Benefit for Late, but Not Early, Passage Mesenchymal Stem Cells on Pain Behaviour in an Animal Model of Osteoarthritis.
Q91940103Therapeutic effect of low-intensity pulsed ultrasound on temporomandibular joint injury induced by chronic sleep deprivation in rats
Q42427785Therapeutic opportunities to prevent post-traumatic arthritis: Lessons from the natural history of arthritis after articular fracture
Q47555068Tissue material properties and computational modelling of the human tibiofemoral joint: a critical review.
Q90054832Topical Application of Wogonin Provides a Novel Treatment of Knee Osteoarthritis
Q90633520Total Knee Arthroplasty with a Ti6Al4V/PEEK Prosthesis on an Osteoarthritis Rat Model: Behavioral and Neurophysiological Analysis
Q94561982Tougu Xiaotong capsule exerts a therapeutic effect by improving knee meniscus in the early osteoarthritis rat model
Q64061321Towards Patient-Specific Computational Modelling of Articular Cartilage on the Basis of Advanced Multiparametric MRI Techniques
Q40726927Transcriptional profiling of bovine intervertebral disc cells: implications for identification of normal and degenerate human intervertebral disc cell phenotypes
Q51907850Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.
Q39251278Transcutaneous treatment with vetdrop(®) sustains the adjacent cartilage in a microfracturing joint defect model in sheep
Q36477409Transient receptor potential ankyrin 1 (TRPA1) receptor is involved in chronic arthritis: in vivo study using TRPA1-deficient mice
Q39961318Transplantation of Achilles tendon treated with bone morphogenetic protein 7 promotes meniscus regeneration in a rat model of massive meniscal defect.
Q43114208Treatment of experimental osteonecrosis of the hip in adult rabbits with a single local injection of recombinant human FGF-2 microspheres
Q43053536Treatment of staphylococcal septic arthritis in rabbits by systemic antibiotics and intra-articular corticosteroids
Q37244895Treatment with SiMiaoFang, an anti-arthritis chinese herbal formula, inhibits cartilage matrix degradation in osteoarthritis rat model
Q34981364UDP-glucose dehydrogenase modulates proteoglycan synthesis in articular chondrocytes: its possible involvement and regulation in osteoarthritis
Q64260268UP1306: A Composition Containing Standardized Extracts of and for Arthritis Management
Q35159282UP3005, a Botanical Composition Containing Two Standardized Extracts of Uncaria gambir and Morus alba, Improves Pain Sensitivity and Cartilage Degradations in Monosodium Iodoacetate-Induced Rat OA Disease Model
Q28540054Ultrasound can detect macroscopically undetectable changes in osteoarthritis reflecting the superficial histological and biochemical degeneration: ex vivo study of rabbit and human cartilage
Q33564495Upregulation of insulin-like growth factor I gene expression in the lesions of osteoarthritic human articular cartilage
Q30393402Usefulness of using laser-induced photoacoustic measurement and 3.0 Tesla MRI to assess knee cartilage damage: a comparison study
Q35548513Validity of histopathological grading of articular cartilage from osteoarthritic knee joints
Q41892349Vascular endothelial growth factor isoforms and their receptors are expressed in human osteoarthritic cartilage
Q35128175Verapamil protects against cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling
Q34918244WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways
Q42376406Warm sparse-dense wave inhibits cartilage degradation in papain-induced osteoarthritis through the mitogen-activated protein kinase signaling pathway
Q41787508Wear-lines and split-lines of human patellar cartilage: relation to tensile biomechanical properties.
Q34221930Xylosyltransferase-I regulates glycosaminoglycan synthesis during the pathogenic process of human osteoarthritis
Q41456605Zonal T2* and T1Gd assessment of knee joint cartilage in various histological grades of cartilage degeneration: an observational in vitro study
Q90675840[Histological diagnostics in joint pathology due to increasing regenerative therapeutic strategies - special consideration for cartilage damage]
Q53065354[Histopathological degeneration score of fibrous cartilage. Low- and high-grade meniscal degeneration].
Q79242502[Histopathological examination of joint degeneration: typing, grading and staging of osteoarthritis]
Q53587851[Implantation of matrix-free cartilage transplants in standardized defects in sheep knee joints].
Q90067427[Lumbar facet joint degeneration contributes to degenerative lumbar scoliosis induced by asymmetric stress in rabbits]
Q84046012[Osteoarthritis--histopathologic diagnosis: typing, grading, and staging]
Q83887013[Osteoarthritis. Etiology, typing, staging and histological grading]
Q79306910[Spontaneous and post-therapeutic cartilage repair: evaluation criteria]
Q83811142[The oncofetal gene survivin - a possible target gene for regenerative therapy concepts in cartilaginous tissue]
Q80537737[Typing, grading and staging of osteoarthritis: histopathological assessment of joint degeneration]
Q42186271iNOS expression and osteocyte apoptosis in idiopathic, non-traumatic osteonecrosis.
Q42269793rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ

Search more.