NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions

scientific article published on 10 February 2016

NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2016NatCo...710554L
P356DOI10.1038/NCOMMS10554
P932PMC publication ID4749981
P698PubMed publication ID26861112
P5875ResearchGate publication ID294278418

P50authorEric VivierQ29033372
Daniel UtzschneiderQ43123785
Greta GuardaQ51956208
Camilla JandusQ53346651
Werner HeldQ87983291
P2093author name stringPedro Romero
Stéphanie Bessoles
Giorgia Rota
Kristina Ludigs
Dietmar Zehn
Francesco Staehli
Wilson Castro
Anh Thu Dang
P2860cites workBioGPS: an extensible and customizable portal for querying and organizing gene annotation resourcesQ21183895
NLR family member NLRC5 is a transcriptional regulator of MHC class I genesQ24338949
Adoptive cell transfer: a clinical path to effective cancer immunotherapyQ24644774
NLRC5, at the Heart of Antigen PresentationQ26823400
Impaired natural killer cell self-education and "missing-self" responses in Ly49-deficient miceQ30413179
The NOD-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer: a case-control study and gene expression analysesQ33717170
Natural killer cell tolerance persists despite significant reduction of self MHC class I on normal target cells in miceQ33722187
Absence of mouse 2B4 promotes NK cell-mediated killing of activated CD8+ T cells, leading to prolonged viral persistence and altered pathogenesisQ33882896
NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cellsQ34260876
Cytokine therapy reverses NK cell anergy in MHC-deficient tumorsQ35140125
Fate mapping analysis of lymphoid cells expressing the NKp46 cell surface receptorQ35546855
NLRC5 exclusively transactivates MHC class I and related genes through a distinctive SXY moduleQ35587277
Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunityQ35709263
Mouse NK cell-mediated rejection of bone marrow allografts exhibits patterns consistent with Ly49 subset licensingQ35776463
NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogensQ35940044
Regulation of class I major histocompatibility complex (MHC) by nucleotide-binding domain, leucine-rich repeat-containing (NLR) proteinsQ36097953
Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway.Q36191417
H-2D ligand expression by Ly49A+ natural killer (NK) cells precludes ligand uptake from environmental cells: implications for NK cell functionQ36370106
Natural killer cell tolerance in mice with mosaic expression of major histocompatibility complex class I transgeneQ36380455
Natural killer cells act as rheostats modulating antiviral T cellsQ36517134
Self-tolerance of natural killer cellsQ36518933
Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell-mediated deletion.Q36547702
Cutting edge: impaired MHC class I expression in mice deficient for Nlrc5/class I transactivatorQ36626948
Cutting edge: viral infection breaks NK cell tolerance to "missing self".Q36983093
Influence of HLA-C expression level on HIV controlQ37200459
Therapeutic depletion of natural killer cells controls persistent infection.Q37547157
Tuning the threshold of natural killer cell responsesQ38070014
Natural killer cells regulate diverse T cell responses.Q38100373
The use of endogenous T cells for adoptive transferQ38170503
NK cell self tolerance, responsiveness and missing self recognitionQ38196030
Education of murine NK cells requires both cis and trans recognition of MHC class I moleculesQ39085577
NLRC5 controls basal MHC class I gene expression in an MHC enhanceosome-dependent mannerQ39366749
NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat modelQ39864722
CD54/ICAM-1 is a costimulator of NK cell-mediated cytotoxicityQ41453526
TRAIL+ NK cells control CD4+ T cell responses during chronic viral infection to limit autoimmunity.Q41678588
The depletion of NK cells prevents T cell exhaustion to efficiently control disseminating virus infectionQ41848792
Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity.Q42211517
HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infectionQ42986755
Class I-deficient hemopoietic cells and nonhemopoietic cells dominantly induce unresponsiveness of natural killer cells to class I-deficient bone marrow cell grafts.Q43918410
The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cellsQ45046743
Viral escape by selection of cytotoxic T cell-resistant virus variants in vivoQ45860175
MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK ActivityQ46345857
T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion.Q50902062
Cutting edge: CD8+ T cell priming in the absence of NK cells leads to enhanced memory responses.Q51020416
NK cell education: not an on-off switch but a tunable rheostat.Q51771715
SHP-1-mediated inhibitory signals promote responsiveness and anti-tumour functions of natural killer cellsQ57039192
Fine tuning of natural killer cell specificity and maintenance of self tolerance in MHC class I-deficient miceQ63363359
Altered expression of Ly49 inhibitory receptors on natural killer cells from MHC class I-deficient miceQ73271250
Cre recombinase-mediated inactivation of H-2Dd transgene expression: evidence for partial missing self-recognition by Ly49A NK cellsQ77198599
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)10554
P577publication date2016-02-10
P1433published inNature CommunicationsQ573880
P1476titleNLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions
P478volume7

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cites work (P2860)
Q26744551"Natural Regulators": NK Cells as Modulators of T Cell Immunity
Q52668670Adenovirus Vector Vaccination Impacts NK Cell Rheostat Function following Lymphocytic Choriomeningitis Virus Infection.
Q57295499Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells
Q55310033CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema.
Q40159847Deficiency of the NOD-Like Receptor NLRC5 Results in Decreased CD8+ T Cell Function and Impaired Viral Clearance
Q48198779EVIR: chimeric receptors that enhance dendritic cell cross-dressing with tumor antigens.
Q91867313Emerging Roles for NLRC5 in Immune Diseases
Q89907531IFI30 Is a Novel Immune-Related Target with Predicting Value of Prognosis and Treatment Response in Glioblastoma
Q93116141NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ
Q37108366NLRC5, a promising new entry in tumor immunology
Q59336655NLRC5: potential novel non-invasive biomarker for predicting and reflecting the progression of IgA nephritis
Q26742166Recognition and Regulation of T Cells by NK Cells
Q64113887STAT1 signaling shields T cells from NK cell-mediated cytotoxicity
Q37598020T Cells Infiltrating Diseased Liver Express Ligands for the NKG2D Stress Surveillance System.
Q61800815The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region
Q57038982The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity

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