Distinct functions of MLH3 at recombination hot spots in the mouse.

scientific article published on April 2008

Distinct functions of MLH3 at recombination hot spots in the mouse. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1534/GENETICS.107.084798
P8608Fatcat IDrelease_c3hobao5rfdhlbpgj73u3wjjuq
P932PMC publication ID2323788
P698PubMed publication ID18430927
P5875ResearchGate publication ID5421822

P50authorFrédéric BaudatQ30093315
P2093author name stringBernard de Massy
Anton Svetlanov
Paula E Cohen
P2860cites workThe DNA mismatch-repair MLH3 protein interacts with MSH4 in meiotic cells, supporting a role for this MutL homolog in mammalian meiotic recombinationQ24300831
Extreme heterogeneity in the molecular events leading to the establishment of chiasmata during meiosis i in human oocytesQ24530701
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female miceQ24606421
Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiaeQ27930781
MLH1 and MSH2 promote the symmetry of double-strand break repair events at the HIS4 hotspot in Saccharomyces cerevisiae.Q27936830
Crossover/noncrossover differentiation, synaptonemal complex formation, and regulatory surveillance at the leptotene/zygotene transition of meiosisQ27936900
Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correctionQ27939611
MSH4 acts in conjunction with MLH1 during mammalian meiosisQ28142773
Comparative analysis of meiotic progression in female mice bearing mutations in genes of the DNA mismatch repair pathwayQ28259874
hMSH4-hMSH5 recognizes Holliday Junctions and forms a meiosis-specific sliding clamp that embraces homologous chromosomesQ28276445
Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing overQ28282791
Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase IQ28505426
Novel and diverse functions of the DNA mismatch repair family in mammalian meiosis and recombinationQ28509276
Meiotic pachytene arrest in MLH1-deficient miceQ28510650
Crossover and noncrossover pathways in mouse meiosisQ28586370
RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in femalesQ28589265
Meiotic arrest and aneuploidy in MLH3-deficient miceQ28593875
Generating crossovers by resolution of nicked Holliday junctions: a role for Mus81-Eme1 in meiosisQ28647386
The Bloom's syndrome helicase suppresses crossing over during homologous recombinationQ29547237
The single-end invasion: an asymmetric intermediate at the double-strand break to double-holliday junction transition of meiotic recombinationQ29618523
Mus81-Eme1 are essential components of a Holliday junction resolvaseQ29619843
Temporal progression of recombination in human malesQ33222301
Cis- and trans-acting elements regulate the mouse Psmb9 meiotic recombination hotspotQ33288732
Single Holliday junctions are intermediates of meiotic recombinationQ33576921
Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesisQ33925085
Competing crossover pathways act during meiosis in Saccharomyces cerevisiaeQ34569381
MLH1 mutations differentially affect meiotic functions in Saccharomyces cerevisiaeQ34617068
MLH1p and MLH3p localize to precociously induced chiasmata of okadaic-acid-treated mouse spermatocytesQ34619470
Fission yeast Mus81.Eme1 Holliday junction resolvase is required for meiotic crossing over but not for gene conversionQ34619495
Evidence for short-patch mismatch repair in Saccharomyces cerevisiaeQ35115265
The Mus81 solution to resolution: generating meiotic crossovers without Holliday junctionsQ35643073
Heteroduplex DNA in meiotic recombination in Drosophila mei-9 mutantsQ35844854
Meiotic recombination in Drosophila Msh6 mutants yields discontinuous gene conversion tractsQ35844948
Initiation of meiotic recombination by formation of DNA double-strand breaks: mechanism and regulationQ36542028
Regulating double-stranded DNA break repair towards crossover or non-crossover during mammalian meiosis.Q36900915
Mlh1 is unique among mismatch repair proteins in its ability to promote crossing-over during meiosisQ38344945
Involvement of nucleotide-excision repair in msh2 pms1-independent mismatch repairQ47979502
Control of meiotic recombination in Arabidopsis: role of the MutL and MutS homologues.Q53007394
Intermediates of Yeast Meiotic Recombination Contain Heteroduplex DNAQ58486283
An initiation site for meiotic crossing-over and gene conversion in the mouseQ74817631
P433issue4
P407language of work or nameEnglishQ1860
P1104number of pages9
P304page(s)1937-1945
P577publication date2008-04-01
P1433published inGeneticsQ3100575
P1476titleDistinct functions of MLH3 at recombination hot spots in the mouse
P478volume178

Reverse relations

cites work (P2860)
Q64928626A mutation in the endonuclease domain of mouse MLH3 reveals novel roles for MutLγ during crossover formation in meiotic prophase I.
Q49886701Age-Dependent Alterations in Meiotic Recombination Cause Chromosome Segregation Errors in Spermatocytes
Q36614680An intact Pms2 ATPase domain is not essential for male fertility
Q44780934Analysis of crossover breakpoints yields new insights into the nature of the gene conversion events associated with large NF1 deletions mediated by nonallelic homologous recombination
Q28482488Characterization of multi-functional properties and conformational analysis of MutS2 from Thermotoga maritima MSB8
Q97518601Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover Formation with Cell-Cycle Progression in a Cyclin-Independent Manner
Q36371989Distinct DNA-binding surfaces in the ATPase and linker domains of MutLγ determine its substrate specificities and exert separable functions in meiotic recombination and mismatch repair
Q34133607Eliminating both canonical and short-patch mismatch repair in Drosophila melanogaster suggests a new meiotic recombination model
Q35007296Estrogenic exposure alters the spermatogonial stem cells in the developing testis, permanently reducing crossover levels in the adult
Q28607925Local and sex-specific biases in crossover vs. noncrossover outcomes at meiotic recombination hot spots in mice
Q33369076MUS81 generates a subset of MLH1-MLH3-independent crossovers in mammalian meiosis
Q27340183Mammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesis
Q28592214Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites
Q33504551Meiotic recombination in human oocytes.
Q64387363Mutation of the ATPase Domain of MutS Homolog-5 (MSH5) Reveals a Requirement for a Functional MutSγ Complex for All Crossovers in Mammalian Meiosis
Q51608115Predicting meiotic pathways in human fetal oogenesis.
Q35754808Reduced Crossover Interference and Increased ZMM-Independent Recombination in the Absence of Tel1/ATM.
Q46244949Regulation of Crossover Frequency and Distribution during Meiotic Recombination.
Q98568696Regulation of the MLH1-MLH3 endonuclease in meiosis
Q37653026The MutSβ complex is a modulator of p53-driven tumorigenesis through its functions in both DNA double-strand break repair and mismatch repair
Q28306188The Saccharomyces cerevisiae Mlh1-Mlh3 heterodimer is an endonuclease that preferentially binds to Holliday junctions
Q33439932The new yeast is a mouse
Q27316957Variation in genome-wide levels of meiotic recombination is established at the onset of prophase in mammalian males
Q42352313mlh3 mutations in baker's yeast alter meiotic recombination outcomes by increasing noncrossover events genome-wide.

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