Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion

scientific article published on 16 February 2016

Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion is …
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scholarly articleQ13442814

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P819ADS bibcode2016NatCo...710686S
P6179Dimensions Publication ID1023519765
P356DOI10.1038/NCOMMS10686
P932PMC publication ID4757769
P698PubMed publication ID26880110
P5875ResearchGate publication ID295101012

P50authorPhilipp E. SchererQ60572448
Jason K KimQ92180750
P2093author name stringMartin Wabitsch
Anil Chawla
Michael P Czech
Olga T Hardy
Rachel J Roth Flach
Hye Lim Noh
Juerg Straubhaar
Ozlem Senol-Cosar
Sarah Nicoloro
Marina DiStefano
P2860cites workChronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistanceQ24617743
Regional differences in cellular mechanisms of adipose tissue gain with overfeedingQ24624643
Obesity is associated with macrophage accumulation in adipose tissueQ27860976
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin ResistanceQ28131660
Characterization of a human preadipocyte cell strain with high capacity for adipose differentiationQ28204416
Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker ratsQ28379378
Prdm16 is required for the maintenance of brown adipocyte identity and function in adult miceQ28593617
Brown adipose tissue: function and physiological significanceQ29547448
Macrophages, inflammation, and insulin resistanceQ29614351
Dynamics of fat cell turnover in humansQ29615688
mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancerQ29617271
An established pre-adipose cell line and its differentiation in culture.Q52826449
Insulin regulation of regional free fatty acid metabolism.Q54108262
Adipose tissue cellularity in human obesityQ66886876
Relationship between replication and differentiation in cultured human adipocyte precursor cellsQ71800347
MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity.Q37100064
Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI.Q37110569
Fibrosis and adipose tissue dysfunctionQ37227722
Tenomodulin gene and obesity-related phenotypesQ37739467
Forming functional fat: a growing understanding of adipocyte differentiationQ37939532
Metabolic syndrome, insulin resistance, and roles of inflammation--mechanisms and therapeutic targetsQ38027826
Dissociating fatty liver and diabetesQ38050214
Differential gene expression in adipose tissue from obese human subjects during weight loss and weight maintenanceQ38324859
Characterization of the transcriptional and functional effects of fibroblast growth factor-1 on human preadipocyte differentiation.Q40215110
Changes in integrin expression during adipocyte differentiationQ40375216
Adipose tissue extracellular matrix: newly organized by adipocytes during differentiationQ41007468
Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammationQ41838863
Lipolysis in intraabdominal adipose tissues of obese women and men.Q42487936
Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistanceQ42518071
Fibronectin modulation of cell shape and lipogenic gene expression in 3T3-adipocytesQ42820082
Regional impact of adipose tissue morphology on the metabolic profile in morbid obesity.Q42911327
Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue.Q43071652
Thiazolidinediones block fatty acid release by inducing glyceroneogenesis in fat cellsQ44367160
Monocyte chemoattractant protein-1 release is higher in visceral than subcutaneous human adipose tissue (AT): implication of macrophages resident in the AT.Q45238657
Hyperinsulinemic-euglycemic clamp to assess insulin sensitivity in vivo.Q45979025
The genetic variation of the tenomodulin gene (TNMD) is associated with serum levels of systemic immune mediators--the Finnish Diabetes Prevention StudyQ46518545
Variations in the size of the major omentum are primarily determined by fat cell numberQ47244322
Tenomodulin is necessary for tenocyte proliferation and tendon maturationQ30979772
Molecular cloning of tenomodulin, a novel chondromodulin-I related geneQ31856755
Adipocyte turnover: relevance to human adipose tissue morphologyQ33556451
Adipocyte apoptosis, a link between obesity, insulin resistance, and hepatic steatosisQ33661588
Tracking adipogenesis during white adipose tissue development, expansion and regenerationQ33824485
Endotrophin triggers adipose tissue fibrosis and metabolic dysfunctionQ33827740
Rapid cellular turnover in adipose tissueQ33847015
Cross species comparison of C/EBPα and PPARγ profiles in mouse and human adipocytes reveals interdependent retention of binding sitesQ33848577
Identification and characterization of a promoter cassette conferring adipocyte-specific gene expressionQ33874460
PPARγ and the global map of adipogenesis and beyondQ33924305
Comparative Epigenomic Analysis of Murine and Human AdipogenesisQ34179692
Diet-induced adipocyte number increase in adult rats: a new model of obesityQ34274248
Body mass index-independent inflammation in omental adipose tissue associated with insulin resistance in morbid obesityQ34307250
Anti-angiogenic action of the C-terminal domain of tenomodulin that shares homology with chondromodulin-I.Q34321659
Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazoneQ34324049
Abdominal subcutaneous and visceral adipose tissue and insulin resistance in the Framingham heart studyQ34551435
Weight reduction modulates expression of genes involved in extracellular matrix and cell death: the GENOBIN studyQ34686210
The genetic variation in the tenomodulin gene is associated with serum total and LDL cholesterol in a body size-dependent mannerQ34871904
Tenomodulin is highly expressed in adipose tissue, increased in obesity, and down-regulated during diet-induced weight lossQ34992294
Inflammatory links between obesity and metabolic diseaseQ35015802
Transplantation of adipose tissue and stem cells: role in metabolism and diseaseQ35184552
Rapid depot-specific activation of adipocyte precursor cells at the onset of obesityQ35235848
Beneficial effects of subcutaneous fat transplantation on metabolismQ35485321
Preferential fat deposition in subcutaneous versus visceral depots is associated with insulin sensitivityQ35498016
ECM roles in the function of metabolic tissues.Q35653088
The extracellular matrix and insulin resistanceQ35812133
Obesity-associated improvements in metabolic profile through expansion of adipose tissueQ35945161
Transcriptional control of adipocyte formationQ35962266
The many faces of PPARgammaQ36344625
Adiposoft: automated software for the analysis of white adipose tissue cellularity in histological sections.Q36387190
Loss of white adipose hyperplastic potential is associated with enhanced susceptibility to insulin resistanceQ36469271
Adipose tissue heterogeneity: implication of depot differences in adipose tissue for obesity complicationsQ36546700
Adiponectin promotes functional recovery after podocyte ablationQ36574746
Gene silencing in adipose tissue macrophages regulates whole-body metabolism in obese miceQ36855257
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectadipocyteQ357519
P304page(s)10686
P577publication date2016-02-16
P1433published inNature CommunicationsQ573880
P1476titleTenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion
P478volume7

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cites work (P2860)
Q38755564APMAP interacts with lysyl oxidase-like proteins, and disruption of Apmap leads to beneficial visceral adipose tissue expansion
Q94569821Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice
Q90893796Adipogenesis and metabolic health
Q90027782Adipose Tissue CTGF Expression is Associated with Adiposity and Insulin Resistance in Humans
Q46200858An Investigation of the Single and Combined Phthalate Metabolite Effects on Human Chorionic Gonadotropin Expression in Placental Cells
Q33600972CYP2J2 and Its Metabolites EETs Attenuate Insulin Resistance via Regulating Macrophage Polarization in Adipose Tissue
Q60305264Combined QTL and Genome Scan Analyses With the Help of 2b-RAD Identify Growth-Associated Genetic Markers in a New Fast-Growing Carp Strain
Q90409951Contribution of adipogenesis to healthy adipose tissue expansion in obesity
Q54123539De novo adipocyte differentiation from Pdgfrβ+ preadipocytes protects against pathologic visceral adipose expansion in obesity.
Q89977189EGR1 Transcription Factor is a Multifaceted Regulator of Matrix Production in Tendons and Other Connective Tissues
Q64118337Effects of X-chromosome Tenomodulin Genetic Variants on Obesity in a Children's Cohort and Implications of the Gene in Adipocyte Metabolism
Q55384230Evaluation and optimization of differentiation conditions for human primary brown adipocytes.
Q34550053Fetal development of subcutaneous white adipose tissue is dependent on Zfp423.
Q37593267HO-1 inhibits preadipocyte proliferation and differentiation at the onset of obesity via ROS dependent activation of Akt2.
Q37536143Inverse relationship of cardioankle vascular index with BMI in healthy Japanese subjects: a cross-sectional study.
Q47553552Lipid Parameters are Independently Associated with Cardio-Ankle Vascular Index (CAVI) in Healthy Japanese Subjects
Q41997397Panax ginseng Leaf Extracts Exert Anti-Obesity Effects in High-Fat Diet-Induced Obese Rats
Q41600009Paradoxical effect of IKKβ inhibition on the expression of E3 ubiquitin ligases and unloading-induced skeletal muscle atrophy
Q47183937Subcutaneous adipose tissue gene expression and DNA methylation respond to both short- and long-term weight loss
Q88999951TACI-Deficient Macrophages Protect Mice Against Metaflammation and Obesity-Induced Dysregulation of Glucose Homeostasis
Q57047042Targeting nuclear receptor NR4A1-dependent adipocyte progenitor quiescence promotes metabolic adaptation to obesity
Q47161195Targeting viperin improves diet-induced glucose intolerance but not adipose tissue inflammation
Q47664036Tenomodulin is essential for prevention of adipocyte accumulation and fibrovascular scar formation during early tendon healing
Q57166261Understanding Tendons: Lessons from Transgenic Mouse Models

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