| scholarly article | Q13442814 |
| P50 | author | Helmut Friess | Q15453363 |
| P2093 | author name string | T M Gress | |
| C Mawrin | |||
| K Dietzmann | |||
| P Malfertheiner | |||
| P Herrera | |||
| M P A Ebert | |||
| G Fei | |||
| L Schandl | |||
| P2860 | cites work | TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta | Q24310394 |
| The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
| P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
| PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer | Q27860985 | ||
| Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers | Q28145813 | ||
| Fibroblast growth factor-5 stimulates mitogenic signaling and is overexpressed in human pancreatic cancer: evidence for autocrine and paracrine actions | Q28251444 | ||
| Infrequent genetic alterations of the PTEN/MMAC1 gene in Japanese patients with primary cancers of the breast, lung, pancreas, kidney, and ovary | Q28259645 | ||
| Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
| Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN | Q28513537 | ||
| Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome | Q29615538 | ||
| Induction of TFF1 gene expression in pancreas overexpressing transforming growth factor alpha | Q30578242 | ||
| Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease. | Q34742581 | ||
| Inherited mutations in PTEN that are associated with breast cancer, cowden disease, and juvenile polyposis | Q35250337 | ||
| Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha | Q35606708 | ||
| Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells | Q35745875 | ||
| Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast | Q35788322 | ||
| Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression | Q36067596 | ||
| Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage. | Q38467346 | ||
| Use of representational difference analysis to study the effect of TGFB on the expression profile of a pancreatic cancer cell line | Q40936571 | ||
| TGFbeta signaling: receptors, transducers, and Mad proteins. | Q41010880 | ||
| TGF-beta-1 up-regulates cyclin D1 expression in COLO-357 cells, whereas suppression of cyclin D1 levels is associated with down-regulation of the type I TGF-beta receptor | Q41688258 | ||
| Role of growth factors in pancreatic cancer. | Q41690572 | ||
| Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival | Q44680447 | ||
| Induction and expression of amphiregulin in human pancreatic cancer. | Q46134755 | ||
| Germline mutations in PTEN are present in Bannayan-Zonana syndrome | Q48046915 | ||
| Differential expression of MMAC/PTEN in glioblastoma multiforme: relationship to localization and prognosis. | Q48230264 | ||
| Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors. | Q48544624 | ||
| Transforming growth factor-beta1 induces desmoplasia in an experimental model of human pancreatic carcinoma | Q60609781 | ||
| Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN | Q64381461 | ||
| Pancreatic carcinoma | Q67734499 | ||
| TGF-beta 1 overexpression in murine pancreas induces chronic pancreatitis and, together with TNF-alpha, triggers insulin-dependent diabetes | Q70881995 | ||
| Induction of platelet‐derived growth factor A and B chains and over‐expression of their receptors in human pancreatic cancer | Q72036047 | ||
| Expression of transforming growth factor beta1 (TGFbeta1) and its receptors in pancreatic duct cell carcinoma and in chronic pancreatitis | Q74582536 | ||
| Recent discoveries in cancer genetics of exocrine pancreatic neoplasia | Q77096089 | ||
| Expression of two angiogenic factors, vascular endothelial growth factor and platelet-derived endothelial cell growth factor in human pancreatic cancer, and its relationship to angiogenesis | Q77668037 | ||
| PTEN mutations in endometrial cancers with 10q LOH: additional evidence for the involvement of multiple tumor suppressors | Q77789624 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | pancreas | Q9618 |
| overexpression | Q61643320 | ||
| P304 | page(s) | 257-262 | |
| P577 | publication date | 2002-01-01 | |
| P1433 | published in | British Journal of Cancer | Q326309 |
| P1476 | title | Reduced PTEN expression in the pancreas overexpressing transforming growth factor-beta 1. | |
| P478 | volume | 86 |
| Q37261852 | A tumor sorting protocol that enables enrichment of pancreatic adenocarcinoma cells and facilitation of genetic analyses |
| Q35132940 | Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis |
| Q40039943 | BMP suppresses PTEN expression via RAS/ERK signaling |
| Q37437827 | Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells |
| Q55453582 | Deregulation of Negative Controls on TGF-β1 Signaling in Tumor Progression. |
| Q48229042 | Differential role of PTEN in transforming growth factor β (TGF-β) effects on proliferation and migration in prostate cancer cells. |
| Q35276917 | EMILIN1-α4/α9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation. |
| Q30481528 | Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis |
| Q34661807 | Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice |
| Q34043823 | Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer |
| Q37322384 | Loss of phosphatase and tensin homolog expression is associated with recurrence and poor prognosis in patients with pancreatic ductal adenocarcinoma |
| Q28393454 | Oxidative stress and glutathione in TGF-beta-mediated fibrogenesis |
| Q34134396 | PTEN loss accelerates KrasG12D-induced pancreatic cancer development |
| Q47140618 | PTEN-Dependent Stabilization of MTSS1 Inhibits Metastatic Phenotype in Pancreatic Ductal Adenocarcinoma |
| Q35870626 | PTENless means more. |
| Q37125627 | Pancreatic carcinogenesis |
| Q24800215 | Pathways for aberrant angiogenesis in pancreatic cancer |
| Q34117879 | RAS/ERK modulates TGFbeta-regulated PTEN expression in human pancreatic adenocarcinoma cells |
| Q47691876 | Regulation of the tumor suppressor PTEN by natural anticancer compounds |
| Q38100279 | Rho-associated coiled-coil kinase (ROCK) signaling and disease |
| Q35919264 | Role of erlotinib in the management of pancreatic cancer. |
| Q45143602 | Study of the PTEN gene expression and FAK phosphorylation in human hepatocarcinoma tissues and cell lines |
| Q43245291 | Synergistic action of Smad4 and Pten in suppressing pancreatic ductal adenocarcinoma formation in mice |
| Q37175517 | TGF-beta downregulates PTEN via activation of NF-kappaB in pancreatic cancer cells |
| Q40018301 | TGF-beta mediates PTEN suppression and cell motility through calcium-dependent PKC-alpha activation in pancreatic cancer cells |
| Q33678064 | TGF-β induces phosphorylation of phosphatase and tensin homolog: implications for fibrosis of the trabecular meshwork tissue in glaucoma |
| Q39943672 | TGFbeta modulates PTEN expression independently of SMAD signaling for growth proliferation in colon cancer cells |
| Q38728616 | TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1. |
| Q40507359 | The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells |
| Q93081350 | The Use of Genetically Engineered Mouse Models for Studying the Function of Mutated Driver Genes in Pancreatic Cancer |
| Q38175297 | The challenge of pancreatic cancer therapy and novel treatment strategy using engineered mesenchymal stem cells. |
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