The central hydrophobic domain of the bovine papillomavirus E5 transforming protein can be functionally replaced by many hydrophobic amino acid sequences containing a glutamine

scientific article published on January 1, 1992

The central hydrophobic domain of the bovine papillomavirus E5 transforming protein can be functionally replaced by many hydrophobic amino acid sequences containing a glutamine is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/JVI.66.1.505-511.1992
P953full work available at URLhttp://jvi.asm.org/cgi/content/abstract/66/1/505
https://europepmc.org/articles/PMC238311
https://europepmc.org/articles/PMC238311?pdf=render
https://journals.asm.org/doi/pdf/10.1128/jvi.66.1.505-511.1992
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1727496/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1727496/pdf/?tool=EBI
P932PMC publication ID238311
P698PubMed publication ID1727496

P2093author name stringD. DiMaio
B. H. Horwitz
R. Kulke
T. Zibello
P2860cites workOncogenic activation of the neu-encoded receptor protein by point mutation and deletionQ42289065
The E5 oncoprotein of bovine papillomavirus is oriented asymmetrically in Golgi and plasma membranesQ42798650
The bovine papillomavirus E5 transforming protein can stimulate the transforming activity of EGF and CSF-1 receptorsQ42835148
Bovine papillomavirus E5 oncoprotein binds to the 16K component of vacuolar H(+)-ATPasesQ44490670
A point mutation in the neu oncogene mimics ligand induction of receptor aggregationQ44611984
Demonstration that a chemically synthesized BPV1 oncoprotein and its C-terminal domain function to induce cellular DNA synthesis.Q53525847
The E5 transforming gene of bovine papillomavirus encodes a small, hydrophobic polypeptide.Q54144933
Efficient transactivation and morphologic transformation by bovine papillomavirus genes expressed from a bovine papillomavirus/simian virus 40 recombinant virusQ33678641
The E5 oncoprotein of bovine papillomavirus binds to a 16 kd cellular proteinQ33916978
Genetic and biochemical definition of the bovine papillomavirus E5 transforming proteinQ33929466
A specific transmembrane domain of a coronavirus E1 glycoprotein is required for its retention in the Golgi regionQ36217608
Transformation and replication in mouse cells of a bovine papillomavirus--pML2 plasmid vector that can be rescued in bacteria.Q36322407
A Golgi retention signal in a membrane-spanning domain of coronavirus E1 proteinQ36532876
A glutamine residue in the membrane-associating domain of the bovine papillomavirus type 1 E5 oncoprotein mediates its binding to a transmembrane component of the vacuolar H(+)-ATPaseQ36656196
Biological properties of the deer papillomavirus E5 gene in mouse C127 cells: growth transformation, induction of DNA synthesis, and activation of the platelet-derived growth factor receptorQ36797809
Genetic evidence that acute morphologic transformation, induction of cellular DNA synthesis, and focus formation are mediated by a single activity of the bovine papillomavirus E5 proteinQ36797883
Transforming activity of a 16-amino-acid segment of the bovine papillomavirus E5 protein linked to random sequences of hydrophobic amino acids.Q36831412
Mutational analysis of bovine papillomavirus type 1 E5 peptide domains involved in induction of cellular DNA synthesisQ36831887
44-amino-acid E5 transforming protein of bovine papillomavirus requires a hydrophobic core and specific carboxyl-terminal amino acidsQ36846314
Molecular cloning and nucleotide sequence of deer papillomavirusQ36850968
Nonsense mutation in open reading frame E2 of bovine papillomavirus DNA.Q36857407
Reindeer papillomavirus transforming properties correlate with a highly conserved E5 regionQ36919518
Activation of the platelet-derived growth factor receptor by the bovine papillomavirus E5 transforming proteinQ41080345
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmicrobiologyQ7193
immunologyQ101929
dysplasiaQ1128996
hydrophobicityQ41854968
P304page(s)505-511
P577publication date1992-01-01
P1433published inJournal of VirologyQ1251128
P1476titleThe central hydrophobic domain of the bovine papillomavirus E5 transforming protein can be functionally replaced by many hydrophobic amino acid sequences containing a glutamine
P478volume66

Reverse relations

cites work (P2860)
Q36656196A glutamine residue in the membrane-associating domain of the bovine papillomavirus type 1 E5 oncoprotein mediates its binding to a transmembrane component of the vacuolar H(+)-ATPase
Q33482628Artificial transmembrane oncoproteins smaller than the bovine papillomavirus E5 protein redefine sequence requirements for activation of the platelet-derived growth factor beta receptor
Q35256418Cellular transformation by a transmembrane peptide: structural requirements for the bovine papillomavirus E5 oncoprotein
Q37475038De novo selection of oncogenes
Q41982551Expression and in Silico analysis of the recombinant bovine papillomavirus E6 protein as a model for viral oncoproteins studies
Q35990329Hydrophobic Mismatch Drives the Interaction of E5 with the Transmembrane Segment of PDGF Receptor
Q35895171Identification of amino acids in the transmembrane and juxtamembrane domains of the platelet-derived growth factor receptor required for productive interaction with the bovine papillomavirus E5 protein
Q41395666Magic angle spinning NMR spectroscopy of membrane proteins
Q33183198Mechanisms of cell transformation by papillomavirus E5 proteins
Q36318177Modulation of cell function by small transmembrane proteins modeled on the bovine papillomavirus E5 protein
Q35000599Multiple transmembrane amino acid requirements suggest a highly specific interaction between the bovine papillomavirus E5 oncoprotein and the platelet-derived growth factor beta receptor
Q36635620Mutation of the bovine papillomavirus E5 oncoprotein at amino acid 17 generates both high- and low-transforming variants
Q35846414Mutational analysis of the interaction between the bovine papillomavirus E5 transforming protein and the endogenous beta receptor for platelet-derived growth factor in mouse C127 cells.
Q40638007Oligomerization of the E5 protein of human papillomavirus type 16 occurs through multiple hydrophobic regions.
Q73562231Overexpression, purification, and structural analysis of the hydrophobic E5 protein from human papillomavirus type 16
Q35642759Papillomavirus E5: the smallest oncoprotein with many functions
Q36634049Specific interaction between the bovine papillomavirus E5 transforming protein and the beta receptor for platelet-derived growth factor in stably transformed and acutely transfected cells
Q40646055Specificity and promiscuity in membrane helix interactions
Q37119249Stable association between the bovine papillomavirus E5 transforming protein and activated platelet-derived growth factor receptor in transformed mouse cells
Q24337640The BPV-1 E5 protein, the 16 kDa membrane pore-forming protein and the PDGF receptor exist in a complex that is dependent on hydrophobic transmembrane interactions
Q34754347The E5 proteins
Q37319770The bovine papillomavirus E5 protein and the PDGF beta receptor: it takes two to tango
Q33644980The bovine papillomavirus E5 protein requires a juxtamembrane negative charge for activation of the platelet-derived growth factor beta receptor and transformation of C127 cells
Q36638250The genomes of the animal papillomaviruses European elk papillomavirus, deer papillomavirus, and reindeer papillomavirus contain a novel transforming gene (E9) near the early polyadenylation site
Q33180948The platelet-derived growth factor beta receptor as a target of the bovine papillomavirus E5 protein
Q41374895Virocrine transformation

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