The platelet-derived growth factor beta receptor as a target of the bovine papillomavirus E5 protein

scientific article

The platelet-derived growth factor beta receptor as a target of the bovine papillomavirus E5 protein is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S1359-6101(00)00012-5
P698PubMed publication ID10959076

P2093author name stringLai CC
DiMaio D
Mattoon D
P2860cites workSignal transduction by receptors with tyrosine kinase activityQ27860624
Vacuolar H(+)-ATPase mutants transform cells and define a binding site for the papillomavirus E5 oncoproteinQ28115609
E5 open reading frame of bovine papillomavirus type 1 encodes a transforming geneQ28286988
Bovine papillomavirus E5 protein induces oligomerization and trans-phosphorylation of the platelet-derived growth factor beta receptorQ33575831
The bovine papillomavirus E5 protein requires a juxtamembrane negative charge for activation of the platelet-derived growth factor beta receptor and transformation of C127 cellsQ33644980
Activation of Neu (ErbB-2) mediated by disulfide bond-induced dimerization reveals a receptor tyrosine kinase dimer interfaceQ33778555
A single amino acid substitution in a WW-like domain of diverse members of the PDGF receptor subfamily of tyrosine kinases causes constitutive receptor activationQ33890119
Cellular transformation by a transmembrane peptide: structural requirements for the bovine papillomavirus E5 oncoproteinQ35256418
Translation of open reading frame E5 of bovine papillomavirus is required for its transforming activityQ35595257
E5 oncoprotein transmembrane mutants dissociate fibroblast transforming activity from 16-kilodalton protein binding and platelet-derived growth factor receptor binding and phosphorylationQ35858985
Identification of amino acids in the transmembrane and juxtamembrane domains of the platelet-derived growth factor receptor required for productive interaction with the bovine papillomavirus E5 proteinQ35895171
Ligand-independent activation of the platelet-derived growth factor beta receptor: requirements for bovine papillomavirus E5-induced mitogenic signalingQ36550896
Transformation-specific interaction of the bovine papillomavirus E5 oncoprotein with the platelet-derived growth factor receptor transmembrane domain and the epidermal growth factor receptor cytoplasmic domainQ36651868
The human papillomavirus type 6 and 16 E5 proteins are membrane-associated proteins which associate with the 16-kilodalton pore-forming proteinQ36653794
The central hydrophobic domain of the bovine papillomavirus E5 transforming protein can be functionally replaced by many hydrophobic amino acid sequences containing a glutamineQ36656359
The E5 gene product of rhesus papillomavirus is an activator of endogenous Ras and phosphatidylinositol-3'-kinase in NIH 3T3 cellsQ36685093
Platelet-derived growth factor receptor can mediate tumorigenic transformation by the bovine papillomavirus E5 proteinQ36690316
Biological properties of the deer papillomavirus E5 gene in mouse C127 cells: growth transformation, induction of DNA synthesis, and activation of the platelet-derived growth factor receptorQ36797809
Genetic evidence that acute morphologic transformation, induction of cellular DNA synthesis, and focus formation are mediated by a single activity of the bovine papillomavirus E5 proteinQ36797883
The conserved C-terminal domain of the bovine papillomavirus E5 oncoprotein can associate with an alpha-adaptin-like molecule: a possible link between growth factor receptors and viral transformationQ36824208
Tumorigenic transformation of murine keratinocytes by the E5 genes of bovine papillomavirus type 1 and human papillomavirus type 16Q36829187
44-amino-acid E5 transforming protein of bovine papillomavirus requires a hydrophobic core and specific carboxyl-terminal amino acidsQ36846314
Virocrine transformation: the intersection between viral transforming proteins and cellular signal transduction pathwaysQ36900312
The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathwaysQ37054452
Localization of bovine papillomavirus type 1 E5 protein to transformed basal keratinocytes and permissive differentiated cells in fibropapilloma tissueQ37071223
Stable association between the bovine papillomavirus E5 transforming protein and activated platelet-derived growth factor receptor in transformed mouse cellsQ37119249
Bovine papillomavirus E5 protein induces the formation of signal transduction complexes containing dimeric activated platelet-derived growth factor beta receptor and associated signaling proteinsQ40891304
Golgi alkalinization by the papillomavirus E5 oncoproteinQ41820272
Autocrine stimulation of intracellular PDGF receptors in v-sis-transformed cellsQ41912351
The E5 oncoprotein of bovine papillomavirus is oriented asymmetrically in Golgi and plasma membranesQ42798650
Dimerization of the p185neu transmembrane domain is necessary but not sufficient for transformationQ42803794
E5 oncoprotein mutants activate phosphoinositide 3-kinase independently of platelet-derived growth factor receptor activationQ42805470
The transmembrane domain of the E5 oncoprotein contains functionally discrete helical facesQ42817465
The bovine papillomavirus E5 transforming protein can stimulate the transforming activity of EGF and CSF-1 receptorsQ42835148
Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virusQ45798186
Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth FactorQ45798365
Structural models of the bovine papillomavirus E5 protein.Q52229470
Oncogenic activation of the PDGF beta receptor by the transmembrane domain of p185neu*.Q53436848
The E5 transforming gene of bovine papillomavirus encodes a small, hydrophobic polypeptide.Q54144933
Viruses in human cancersQ56486194
Phosphospecific antibodies reveal temporal regulation of platelet-derived growth factor beta receptor signalingQ73236377
Erythropoietin receptor activation by a ligand-induced conformation changeQ78111818
P433issue4
P304page(s)283-293
P577publication date2000-12-01
P1433published inCytokine and Growth Factor ReviewsQ15763303
P1476titleThe platelet-derived growth factor beta receptor as a target of the bovine papillomavirus E5 protein
P478volume11

Reverse relations

cites work (P2860)
Q51774818Activated platelet-derived growth factor beta receptor expression, PI3K-AKT pathway molecular analysis, and transforming signals in equine sarcoids.
Q81311229Bovine papillomavirus E5 oncoprotein binds to the activated form of the platelet-derived growth factor beta receptor in naturally occurring bovine urinary bladder tumours
Q33962694Human papillomavirus immortalization and transformation functions
Q36550902Human papillomaviruses and cervical cancer
Q40794484Identification of the transmembrane dimer interface of the bovine papillomavirus E5 protein
Q43092375In vitro dimerization of the bovine papillomavirus E5 protein transmembrane domain
Q36318177Modulation of cell function by small transmembrane proteins modeled on the bovine papillomavirus E5 protein
Q33289844Packing contacts can mediate highly specific interactions between artificial transmembrane proteins and the PDGFbeta receptor
Q37682495Papillomavirus-associated cutaneous neoplasia in mammals
Q40471258Productive interaction between transmembrane mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor beta receptor.
Q35209257Sequence motifs, polar interactions and conformational changes in helical membrane proteins
Q42818709Transactivation of the cyclin A promoter by bovine papillomavirus type 4 E5 protein
Q39732619Transmembrane domains 1 and 2 of the latent membrane protein 1 of Epstein-Barr virus contain a lipid raft targeting signal and play a critical role in cytostasis
Q40654172Upregulation of Swelling‐Activated Cl− Channel Sensitivity to Cell Volume by Activation of EGF Receptors in Murine Mammary Cells
Q42518739c-Src activation by the E5 oncoprotein enables transformation independently of PDGF receptor activation

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