c-Src activation by the E5 oncoprotein enables transformation independently of PDGF receptor activation

scientific article

c-Src activation by the E5 oncoprotein enables transformation independently of PDGF receptor activation is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1013884697
P356DOI10.1038/SJ.ONC.1205223
P698PubMed publication ID11896601
P5875ResearchGate publication ID11466412

P2093author name stringRichard Schlegel
Frank A Suprynowicz
Astrid Baege
Iruvanti Sunitha
P2860cites workThe SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytesQ24304668
Mechanism of activation of protein kinase B by insulin and IGF-1Q24309528
Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60srcQ24614033
Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assemblyQ24642753
A new technique for the assay of infectivity of human adenovirus 5 DNAQ27860797
Vacuolar H(+)-ATPase mutants transform cells and define a binding site for the papillomavirus E5 oncoproteinQ28115609
Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformationQ28187857
E5 open reading frame of bovine papillomavirus type 1 encodes a transforming geneQ28286988
Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunitQ28508052
Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell lineQ29547239
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transductionQ29618388
Src family kinases are required for integrin but not PDGFR signal transduction.Q30014832
The v-Src SH3 Domain Binds Phosphatidylinositol 3'-KinaseQ30194840
Src-homology 3 domain of protein kinase p59fyn mediates binding to phosphatidylinositol 3-kinase in T cellsQ30194870
A quantitative in vitro focus assay for bovine papilloma virusQ45803536
Rapid protein kinase assay using phosphocellulose-paper absorptionQ48456022
The E5 transforming gene of bovine papillomavirus encodes a small, hydrophobic polypeptide.Q54144933
Dissociation of transforming and trans-activation functions for bovine papillomavirus type 1.Q54151145
Genetic analysis of the 3' early region transformation and replication functions of bovine papillomavirus type 1.Q64956444
Tyrphostins IV--highly potent inhibitors of EGF receptor kinase. Structure-activity relationship study of 4-anilidoquinazolinesQ71702568
Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinaseQ30453995
The platelet-derived growth factor beta receptor as a target of the bovine papillomavirus E5 proteinQ33180948
Bovine papillomavirus E5 protein induces oligomerization and trans-phosphorylation of the platelet-derived growth factor beta receptorQ33575831
Src family tyrosine kinases and growth factor signalingQ33810017
Adhesion-linked kinases in cancer; emphasis on src, focal adhesion kinase and PI 3-kinaseQ34013783
Selected glimpses into the activation and function of Src kinaseQ34103644
Role of Src expression and activation in human cancerQ34103650
Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. International biological study on cervical cancer (IBSCC) Study GroupQ34313864
c-Src protein expression is increased in human breast cancer. An immunohistochemical and biochemical analysisQ34414942
Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinaseQ34429291
Receptor tyrosine kinasesQ35225814
Phosphatidylinositol-3 kinase and growth regulationQ35241264
Translation of open reading frame E5 of bovine papillomavirus is required for its transforming activityQ35595257
E5 oncoprotein transmembrane mutants dissociate fibroblast transforming activity from 16-kilodalton protein binding and platelet-derived growth factor receptor binding and phosphorylationQ35858985
Association of p60c-src with endosomal membranes in mammalian fibroblastsQ36533201
Ligand-independent activation of the platelet-derived growth factor beta receptor: requirements for bovine papillomavirus E5-induced mitogenic signalingQ36550896
ErbB3 is involved in activation of phosphatidylinositol 3-kinase by epidermal growth factorQ36653753
Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variantsQ36685443
Thrombin-dependent association of phosphatidylinositol-3 kinase with p60c-src and p59fyn in human plateletsQ36716953
Platelet-derived growth factor induces multisite phosphorylation of pp60c-src and increases its protein-tyrosine kinase activity.Q36793338
The conserved C-terminal domain of the bovine papillomavirus E5 oncoprotein can associate with an alpha-adaptin-like molecule: a possible link between growth factor receptors and viral transformationQ36824208
Overexpressed pp60c-src can induce focus formation without complete transformation of NIH 3T3 cellsQ36888885
Stable association between the bovine papillomavirus E5 transforming protein and activated platelet-derived growth factor receptor in transformed mouse cellsQ37119249
The product of the protooncogene c-src is modified during the cellular response to platelet-derived growth factorQ37537225
Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformationQ39576120
In Vitro Transformation by Bovine Papilloma VirusQ40253765
Transforming proteins of the papillomavirusesQ40584464
Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasiaQ40854169
Oncoprotein networksQ41352439
Altered tyrosine 527 phosphorylation and mitotic activation of p60c-srcQ41699923
Golgi alkalinization by the papillomavirus E5 oncoproteinQ41820272
Rapid plasma membrane anchoring of newly synthesized p59fyn: selective requirement for NH2-terminal myristoylation and palmitoylation at cysteine-3.Q41838604
The primary structure and genetic organization of the bovine papillomavirus type 1 genomeQ42665433
The E5 oncoprotein of bovine papillomavirus is oriented asymmetrically in Golgi and plasma membranesQ42798650
E5 oncoprotein mutants activate phosphoinositide 3-kinase independently of platelet-derived growth factor receptor activationQ42805470
The transmembrane domain of the E5 oncoprotein contains functionally discrete helical facesQ42817465
Epidermal‐Growth‐Factor‐Dependent Activation of the Src‐Family KinasesQ42833014
The bovine papillomavirus E5 transforming protein can stimulate the transforming activity of EGF and CSF-1 receptorsQ42835148
Phosphoinositide 3-kinase: the key switch mechanism in insulin signallingQ42991205
Bovine papillomavirus E5 oncoprotein binds to the 16K component of vacuolar H(+)-ATPasesQ44490670
In vitro tumorigenic transformation by a defined sub-genomic fragment of bovine papilloma virus DNA.Q45803261
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)1695-1706
P577publication date2002-03-01
P1433published inOncogeneQ1568657
P1476titlec-Src activation by the E5 oncoprotein enables transformation independently of PDGF receptor activation
P478volume21

Reverse relations

cites work (P2860)
Q81298973Are transforming properties of the bovine papillomavirus E5 protein shared by E5 from high-risk human papillomavirus type 16?
Q26998701Bovine and human papillomaviruses: a comparative review
Q37411628Karyopherin beta3: a new cellular target for the HPV-16 E5 oncoprotein
Q24656125Koilocytosis: a cooperative interaction between the human papillomavirus E5 and E6 oncoproteins
Q36596250Molecular mechanisms underlying the apoptotic effect of KCNB1 K+ channel oxidation
Q35642759Papillomavirus E5: the smallest oncoprotein with many functions
Q40471258Productive interaction between transmembrane mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor beta receptor.
Q40372322Similarities and differences between the E5 oncoproteins of bovine papillomaviruses type 1 and type 4: cytoskeleton, motility and invasiveness in E5-transformed bovine and mouse cells
Q34754347The E5 proteins
Q37319770The bovine papillomavirus E5 protein and the PDGF beta receptor: it takes two to tango
Q39766239Transcriptional changes induced by bovine papillomavirus type 1 in equine fibroblasts

Search more.