Adeno-associated virus Rep protein inhibits human immunodeficiency virus type 1 production in human cells

scientific article published on January 1, 1991

Adeno-associated virus Rep protein inhibits human immunodeficiency virus type 1 production in human cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/JVI.65.1.396-404.1991
P953full work available at URLhttp://jvi.asm.org/cgi/content/abstract/65/1/396
https://europepmc.org/articles/PMC240530
https://europepmc.org/articles/PMC240530?pdf=render
https://journals.asm.org/doi/pdf/10.1128/jvi.65.1.396-404.1991
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1845899/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1845899/pdf/?tool=EBI
P932PMC publication ID240530
P698PubMed publication ID1845899

P2093author name stringA. B. Rabson
I. L. Miller
B. J. Carter
N. Chejanovsky
B. A. Antoni
J. P. Trempe
P2860cites workTrans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA virusesQ24627466
Regulation of adeno-associated virus gene expression in 293 cells: control of mRNA abundance and translationQ24646629
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cellsQ27860607
A new technique for the assay of infectivity of human adenovirus 5 DNAQ27860797
Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular cloneQ29547734
Characteristics of a human cell line transformed by DNA from human adenovirus type 5Q29547863
Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell cloneQ33847737
The trans-activator gene of HTLV-III is essential for virus replicationQ34161962
The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activityQ34186060
The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeatQ34564367
Location of the trans-activating region on the genome of human T-cell lymphotropic virus type III.Q34564460
Characterization of adeno-associated virus rep proteins in human cells by antibodies raised against rep expressed in Escherichia coliQ36289406
Adeno-associated virus vector for high-frequency integration, expression, and rescue of genes in mammalian cellsQ36425596
Mutation of a consensus purine nucleotide binding site in the adeno-associated virus rep gene generates a dominant negative phenotype for DNA replicationQ36804036
In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivityQ36825840
Identification of nuclear proteins that specifically interact with adeno-associated virus type 2 inverted terminal repeat hairpin DNA.Q36829325
Factors that bind to adeno-associated virus terminal repeats.Q36829404
Expression from the adeno-associated virus p5 and p19 promoters is negatively regulated in trans by the rep proteinQ36831270
Adeno-associated virus gene expression inhibits cellular transformation by heterologous genesQ36838187
Identification of the trans-acting Rep proteins of adeno-associated virus by antibodies to a synthetic oligopeptideQ36869164
Synthesis of functional human immunodeficiency virus tat protein in baculovirus as determined by a cell-cell fusion assayQ36873184
Positive and negative autoregulation of the adeno-associated virus type 2 genomeQ36883901
Construction of a genetic switch for inducible trans-activation of gene expression in eucaryotic cellsQ36887447
Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutantsQ36893013
Negative and positive regulation in trans of gene expression from adeno-associated virus vectors in mammalian cells by a viral rep gene productQ36918659
Genetic analysis of adeno-associated virus: properties of deletion mutants constructed in vitro and evidence for an adeno-associated virus replication functionQ36918727
Elevated levels of mRNA can account for the trans-activation of human immunodeficiency virusQ37412665
Use of adeno-associated virus as a mammalian DNA cloning vector: transduction of neomycin resistance into mammalian tissue culture cellsQ37573696
Silencing of human immunodeficiency virus long terminal repeat expression by an adenovirus E1a mutantQ37694247
Strategies for antiviral therapy in AIDS.Q38172146
Regulatory pathways governing HIV-1 replicationQ38360638
Regulation of HIV and HTLV gene expressionQ39289382
Mysteries of HIV: challenges for therapy and preventionQ39643153
The adeno-associated virus rep gene suppresses herpes simplex virus-induced DNA amplificationQ40109360
Defective-interfering particles of the human parvovirus adeno-associated virusQ40227691
Purification of the human immunodeficiency virus type 1 enhancer and TAR binding proteins EBP-1 and UBP-1.Q42735234
Effect of adeno-associated virus on transformation of NIH 3T3 cells by ras gene and on tumorigenicity of an NIH 3T3 transformed cell lineQ42811726
Mutational analysis of HIV-1 Tat minimal domain peptides: identification of trans-dominant mutants that suppress HIV-LTR-driven gene expressionQ44389543
The AIDS virusQ44559514
The trans-activator gene of the human T cell lymphotropic virus type III is required for replicationQ44579665
Transcription maps of polyoma virus-specific RNA: analysis by two-dimensional nuclease S1 gel mapping.Q44693409
Cloning of infectious adeno-associated virus genomes in bacterial plasmidsQ45796085
Inhibition of adenovirus oncogenicity in hamsters by adeno-associated virus DNAQ45801062
Inhibition of adenovirus-transformed cell oncogenicity by adeno-associated virusQ45801642
Inhibition of Adenovirus 12 Oncogenicity by Adeno-Associated VirusQ45810680
Influence of adeno-associated satellite virus on adenovirus-induced tumours in hamstersQ45819832
Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator proteinQ45830211
Trans-activation of human immunodeficiency virus occurs via a bimodal mechanismQ45830933
Trans-activator gene of human T-lymphotropic virus type III (HTLV-III).Q45838520
Effect of a viral rep gene on transformation of cells by an adeno-associated virus vectorQ45840914
Adeno-associated viruses inhibit SV40 DNA amplification and replication of herpes simplex virus in SV40-transformed hamster cellsQ45841628
The adeno-associated virus Rep78 gene inhibits cellular transformation induced by bovine papillomavirusQ45845384
Genomic heterogeneity of AIDS retroviral isolates from North America and Zaire.Q53896192
Expression and rescue of a nonselected marker from an integrated AAV vector.Q54378201
Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev functionQ58611466
Replication of a human parvovirus nonsense mutant in mammalian cells containing an inducible amber suppressorQ64379115
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectimmunologyQ101929
microbiologyQ7193
viral gene expression regulationQ70682269
viral replicationQ114773374
P304page(s)396-404
P577publication date1991-01-01
P1433published inJournal of VirologyQ1251128
P1476titleAdeno-associated virus Rep protein inhibits human immunodeficiency virus type 1 production in human cells
P478volume65

Reverse relations

cites work (P2860)
Q41936136A directed evolution approach to select for novel Adeno-associated virus capsids on an HIV-1 producer T cell line.
Q33952832A genetic screen identifies a cellular regulator of adeno-associated virus.
Q35839786A maltose-binding protein/adeno-associated virus Rep68 fusion protein has DNA-RNA helicase and ATPase activities
Q39522533Acquisition of the human adeno-associated virus type-2 rep gene by human herpesvirus type-6
Q33799345Adeno-associated virus major Rep78 protein disrupts binding of TATA-binding protein to the p97 promoter of human papillomavirus type 16
Q34717163Adeno-associated virus rep protein-mediated inhibition of transcription of the adenovirus major late promoter in vitro
Q35666040Adeno-associated virus type 2 modulates the host DNA damage response induced by herpes simplex virus 1 during coinfection.
Q40039173Adeno-associated virus type 2 rep gene-mediated inhibition of basal gene expression of human immunodeficiency virus type 1 involves its negative regulatory functions.
Q42428565Adenovirus vectors block human immunodeficiency virus-1 replication in human alveolar macrophages by inhibition of the long terminal repeat
Q34064238An antibody that binds the immunoglobulin CDR3-like region of the CD4 molecule inhibits provirus transcription in HIV-infected T cells.
Q24646235Analysis of adeno-associated virus (AAV) wild-type and mutant Rep proteins for their abilities to negatively regulate AAV p5 and p19 mRNA levels
Q35877884Analysis of recombinant adeno-associated virus packaging and requirements for rep and cap gene products
Q33653198Analysis of the effects of charge cluster mutations in adeno-associated virus Rep68 protein in vitro
Q35879908Binding sites for adeno-associated virus Rep proteins within the human genome.
Q36548752Cellular recombination pathways and viral terminal repeat hairpin structures are sufficient for adeno-associated virus integration in vivo and in vitro.
Q39596582Charge-to-alanine mutagenesis of the adeno-associated virus type 2 Rep78/68 proteins yields temperature-sensitive and magnesium-dependent variants
Q59359941Efficiency and Specificity of Targeted Integration Mediated by the Adeno-Associated Virus Serotype 2 Rep 78 Protein
Q40964386Enhancement of UV-induced cytotoxicity by the adeno-associated virus replication proteins
Q30877436Expression of human herpesvirus 6B rep within infected cells and binding of its gene product to the TATA-binding protein in vitro and in vivo
Q33819589Factors affecting the terminal resolution site endonuclease, helicase, and ATPase activities of adeno-associated virus type 2 Rep proteins
Q34341823Herpes simplex virus type 1/adeno-associated virus hybrid vectors mediate site-specific integration at the adeno-associated virus preintegration site, AAVS1, on human chromosome 19.
Q34015943How adeno-associated virus Rep78 protein arrests cells completely in S phase
Q35844971Human herpesvirus 6A ts suppresses both transformation by H-ras and transcription by the H-ras and human immunodeficiency virus type 1 promoters
Q41101590Human immunodeficiency virus-1 proviral gene disruption by targeted gene therapy: a hypothetical technique for the elimination of provirus from the infected cells
Q36641826Identification of a DNA-binding domain in the amino terminus of adeno-associated virus Rep proteins
Q24293657Identification of a cytoplasmic interaction partner of the large regulatory proteins Rep78/Rep68 of adeno-associated virus type 2 (AAV-2)
Q37748110Identification of an adeno-associated virus Rep protein binding site in the adenovirus E2a promoter
Q37033220Identification of cellular proteins that interact with the adeno-associated virus rep protein
Q36624752Identification of linear DNA sequences that specifically bind the adeno-associated virus Rep protein.
Q36690856In vitro resolution of adeno-associated virus DNA hairpin termini by wild-type Rep protein is inhibited by a dominant-negative mutant of rep
Q45879060Inhibition of bovine papillomavirus plasmid DNA replication by adeno-associated virus
Q35859014Interaction of wild-type and mutant adeno-associated virus (AAV) Rep proteins on AAV hairpin DNA.
Q39871566Mutational analysis of adeno-associated virus Rep protein-mediated inhibition of heterologous and homologous promoters
Q34057580Negative regulation of the adeno-associated virus (AAV) P5 promoter involves both the P5 rep binding site and the consensus ATP-binding motif of the AAV Rep68 protein
Q38356260PKA/PrKX activity is a modulator of AAV/adenovirus interaction
Q40851727Prospects for virus-based gene therapy for cystic fibrosis
Q34419803Proteins attached to viral genomes are multifunctional
Q40933734Recombinant AAV-2 harboring gfp-antisense/ribozyme fusion sequences monitor transduction, gene expression, and show anti-HIV-1 efficacy
Q39878393Recombinant adeno-associated virus mediates a high level of gene transfer but less efficient integration in the K562 human hematopoietic cell line
Q39873805Recruitment of wild-type and recombinant adeno-associated virus into adenovirus replication centers
Q40756505Regulation of human immunodeficiency virus infection: implications for pathogenesis
Q39880225Role for highly regulated rep gene expression in adeno-associated virus vector production
Q41381265Sequence elements of the adeno-associated virus rep gene required for suppression of herpes-simplex-virus-induced DNA amplification
Q39580779Site-specific integration in mammalian cells mediated by a new hybrid baculovirus-adeno-associated virus vector.
Q40510442Site-specific integration of functional transgenes into the human genome by adeno/AAV hybrid vectors.
Q89783875The Carter Lab at NIH: A Model of Inclusive Excellence in Biomedical Research
Q35865107The Rep68 protein of adeno-associated virus type 2 stimulates expression of the platelet-derived growth factor B c-sis proto-oncogene.
Q34280639The adeno-associated virus type 2 Rep protein regulates RNA processing via interaction with the transcription template
Q22008522The adeno-associated virus type 2 regulatory proteins rep78 and rep68 interact with the transcriptional coactivator PC4.
Q35887002The cytotoxicity of the parvovirus minute virus of mice nonstructural protein NS1 is related to changes in the synthesis and phosphorylation of cell proteins
Q40597354The human immunodeficiency virus type-1 long terminal repeat and its role in gene expression
Q38293578The trans‐inhibitory Rep78 protein of adeno‐associated virus binds to TAR region DNA of the human immunodeficiency virus type 1 long terminal repeat
Q35228018Use of Adeno-Associated Virus as a General Transduction Vector for Mammalian Cells
Q37945189Viral hybrid vectors for somatic integration - are they the better solution?

Search more.