Analysis of recombinant adeno-associated virus packaging and requirements for rep and cap gene products

scientific article published in March 1997

Analysis of recombinant adeno-associated virus packaging and requirements for rep and cap gene products is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/JVI.71.3.1897-1905.1997
P932PMC publication ID191262
P698PubMed publication ID9032320

P2093author name stringWadsworth SC
Vincent KA
Piraino ST
P2860cites workTranscriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A proteinQ24309481
Site-specific integration by adeno-associated virusQ24558738
A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactionsQ24597783
Analysis of adeno-associated virus (AAV) wild-type and mutant Rep proteins for their abilities to negatively regulate AAV p5 and p19 mRNA levelsQ24646235
Regulation of adeno-associated virus gene expression in 293 cells: control of mRNA abundance and translationQ24646629
Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectorsQ24682739
Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesisQ24684374
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymeraseQ26778389
Selective extraction of polyoma DNA from infected mouse cell culturesQ29547500
Characteristics of a human cell line transformed by DNA from human adenovirus type 5Q29547863
Integration of the adeno-associated virus genome into cellular DNA in latently infected human Detroit 6 cellsQ33914608
Latent infection of KB cells with adeno-associated virus type 2Q33927814
Amber, ochre and opal suppressor tRNA genes derived from a human serine tRNA gene.Q33930874
Purification of an adenovirus-coded DNA polymerase that is required for initiation of DNA replicationQ53563525
Replication of a human parvovirus nonsense mutant in mammalian cells containing an inducible amber suppressorQ64379115
Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lungQ64382719
Negative regulation of the adeno-associated virus (AAV) P5 promoter involves both the P5 rep binding site and the consensus ATP-binding motif of the AAV Rep68 proteinQ34057580
Use of Adeno-Associated Virus as a General Transduction Vector for Mammalian CellsQ35228018
Adeno-associated virus vectorsQ35305418
Adeno-associated virus vectors preferentially transduce cells in S phase.Q35754006
Adeno-associated virus vectors transduce primary cells much less efficiently than immortalized cells.Q35833899
Targeted integration of adeno-associated virus (AAV) into human chromosome 19Q35936149
Selection and preliminary characterization of temperature-sensitive mutants of type 5 adenovirusQ36588367
Characterization of cell lines that inducibly express the adeno-associated virus Rep proteinsQ36624044
Identification of linear DNA sequences that specifically bind the adeno-associated virus Rep protein.Q36624752
Efficient gene transfer into nondividing cells by adeno-associated virus-based vectors.Q36634983
Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vectorQ36663364
Adeno-associated virus Rep protein inhibits human immunodeficiency virus type 1 production in human cellsQ36688082
Sequences required for coordinate induction of adeno-associated virus p19 and p40 promoters by Rep proteinQ36693546
Adeno-associated virus P5 promoter contains an adenovirus E1A-inducible element and a binding site for the major late transcription factorQ36829959
Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expressionQ36830429
Expression from the adeno-associated virus p5 and p19 promoters is negatively regulated in trans by the rep proteinQ36831270
Adeno-associated virus gene expression inhibits cellular transformation by heterologous genesQ36838187
Adeno-associated virus general transduction vectors: analysis of proviral structuresQ36868692
Identification of the trans-acting Rep proteins of adeno-associated virus by antibodies to a synthetic oligopeptideQ36869164
Positive and negative autoregulation of the adeno-associated virus type 2 genomeQ36883901
Negative and positive regulation in trans of gene expression from adeno-associated virus vectors in mammalian cells by a viral rep gene productQ36918659
Mutational analysis of adeno-associated virus Rep protein-mediated inhibition of heterologous and homologous promotersQ39871566
High-level expression of adeno-associated virus (AAV) Rep78 or Rep68 protein is sufficient for infectious-particle formation by a rep-negative AAV mutantQ39872328
Adeno-associated virus type 2 rep gene-mediated inhibition of basal gene expression of human immunodeficiency virus type 1 involves its negative regulatory functions.Q40039173
Cell lines inducibly expressing the adeno-associated virus (AAV) rep gene: requirements for productive replication of rep-negative AAV mutantsQ40042369
The adeno-associated virus rep gene suppresses herpes simplex virus-induced DNA amplificationQ40109360
Adeno-associated virus vectors for gene therapyQ40429008
The cryptic life style of adeno-associated virusQ40524042
Prospects for the use of adeno-associated virus as a vector for human gene therapyQ40643988
Adeno-associated virus: a vector system for efficient introduction and integration of DNA into a variety of mammalian cell typesQ40660263
High-efficiency transfer of the T cell co-stimulatory molecule B7-2 to lymphoid cells using high-titer recombinant adeno-associated virus vectorsQ41263327
Cell lines for the production of recombinant adeno-associated virusQ41286219
Generation of recombinant adeno-associated virus (rAAV) from an adenoviral vector and functional reconstitution of the NADPH-oxidaseQ41304538
Regulated high-level human beta-globin gene expression in erythroid cells following recombinant adeno-associated virus-mediated gene transferQ41329085
An improved system for packaging recombinant adeno-associated virus vectors capable of in vivo transduction.Q41396968
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brainQ42280576
Gene expression in adeno-associated virus vectors: the effects of chimeric mRNA structure, helper virus, and adenovirus VA1 RNA.Q42500842
Adeno-associated virus type 2-mediated inhibition of human immunodeficiency virus type 1 (HIV-1) replication: involvement of p78rep/p68rep and the HIV-1 long terminal repeatQ43712032
Epidemiology of adenovirus-associated virus infection in a nursery populationQ44631695
A BASIC computer program for analyzing endpoint assaysQ44845101
Efficient synthesis of adeno-associated virus structural proteins requires both adenovirus DNA binding protein and VA I RNA.Q45846371
Increased titer of recombinant AAV vectors by gene transfer with adenovirus coupled to DNA-polylysine complexesQ45867335
Establishment and characterization of KB cell lines latently infected with adeno-associated virus type 1Q45887287
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)1897-1905
P577publication date1997-03-01
P1433published inJournal of VirologyQ1251128
P1476titleAnalysis of recombinant adeno-associated virus packaging and requirements for rep and cap gene products
P478volume71

Reverse relations

cites work (P2860)
Q40916579A helper virus-free packaging system for recombinant adeno-associated virus vectors
Q40894016A method for the preparation of highly purified adeno-associated virus using affinity column chromatography, protease digestion and solvent extraction
Q40994121Adeno-associated virus expression systems for gene transfer
Q24563214Adeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminus
Q28208569Adenovirus encoding HIV-1 Vpr activates caspase 9 and induces apoptotic cell death in both p53 positive and negative human tumor cell lines
Q39581575An adenovirus type 5 mutant with the preterminal protein gene deleted efficiently provides helper functions for the production of recombinant adeno-associated virus
Q33784934Characterization of wild-type adeno-associated virus type 2-like particles generated during recombinant viral vector production and strategies for their elimination
Q40619808Construction of adeno-associated virus packaging plasmids and cells that directly select for AAV helper functions
Q39882175Control of adeno-associated virus type 2 cap gene expression: relative influence of helper virus, terminal repeats, and Rep proteins.
Q97527299Creation of a High-Yield AAV Vector Production Platform in Suspension Cells Using a Design-of-Experiment Approach
Q36288924Current issues in adeno-associated viral vector production
Q40949297Efficient production of adeno-associated virus vectors using split-type helper plasmids
Q24527221Efficient replication of adeno-associated virus type 2 vectors: a cis-acting element outside of the terminal repeats and a minimal size
Q39682511Feasibility of generating adeno-associated virus packaging cell lines containing inducible adenovirus helper genes
Q33607774Gene transfer approaches to the lysosomal storage disorders
Q42448457Herpes simplex virus type 1/adeno-associated virus hybrid vectors
Q34447817Hot topics in adeno-associated virus as a gene transfer vector
Q35891981Identification and elimination of replication-competent adeno-associated virus (AAV) that can arise by nonhomologous recombination during AAV vector production
Q39941005Improved splicing of adeno-associated viral (AAV) capsid protein-supplying pre-mRNAs leads to increased recombinant AAV vector production
Q35159598Interleukin-17 retinotoxicity is prevented by gene transfer of a soluble interleukin-17 receptor acting as a cytokine blocker: implications for age-related macular degeneration.
Q89932125MicroRNA-based recombinant AAV vector assembly improves efficiency of suicide gene transfer in a murine model of lymphoma
Q41634721New developments in the generation of Ad-free, high-titer rAAV gene therapy vectors
Q44953303Novel anti-VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization.
Q44586325Optimization of packaging of adeno-associated virus gene therapy vectors using plasmid transfections
Q40793707Optimization of recombinant adeno-associated virus production using an herpes simplex virus amplicon system
Q33783728Packaging cells based on inducible gene amplification for the production of adeno-associated virus vectors
Q24523073Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus
Q34070162Production of recombinant adeno-associated virus
Q40937480Production of recombinant adeno-associated virus vectors using a packaging cell line and a hybrid recombinant adenovirus
Q28478598Productive parvovirus B19 infection of primary human erythroid progenitor cells at hypoxia is regulated by STAT5A and MEK signaling but not HIFα
Q40746271Recombinant adeno-associated viral vector production using stable packaging and producer cell lines
Q39882313Recombinant adeno-associated virus type 2 replication and packaging is entirely supported by a herpes simplex virus type 1 amplicon expressing Rep and Cap
Q40705869Replication competent helper functions for recombinant AAV vector generation
Q39880225Role for highly regulated rep gene expression in adeno-associated virus vector production
Q43567043Titration of AAV-2 particles via a novel capsid ELISA: packaging of genomes can limit production of recombinant AAV-2.
Q37134005Toward exascale production of recombinant adeno-associated virus for gene transfer applications
Q37479802Transient transfection methods for clinical adeno-associated viral vector production
Q43546899Viral delivery of recombinant short hairpin RNAs

Search more.