scholarly article | Q13442814 |
P2093 | author name string | J Li | |
R J Samulski | |||
X Xiao | |||
P2860 | cites work | Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein | Q24309481 |
Adenovirus E1A proteins interact with the cellular YY1 transcription factor | Q24313191 | ||
Site-specific integration by adeno-associated virus | Q24558738 | ||
Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA | Q24562760 | ||
Regulation of adeno-associated virus gene expression in 293 cells: control of mRNA abundance and translation | Q24646629 | ||
Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors | Q24682739 | ||
Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis | Q24684374 | ||
Selective extraction of polyoma DNA from infected mouse cell cultures | Q29547500 | ||
Trans-activation of the human immunodeficiency virus long terminal repeat sequences, expressed in an adenovirus vector, by the adenovirus E1A 13S protein | Q33580416 | ||
Use of Adeno-Associated Virus as a General Transduction Vector for Mammalian Cells | Q35228018 | ||
Site-specific integration by adeno-associated virus is directed by a cellular DNA sequence | Q35829692 | ||
Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector | Q35872651 | ||
The adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infection | Q35876419 | ||
Analysis of recombinant adeno-associated virus packaging and requirements for rep and cap gene products | Q35877884 | ||
Targeted integration of adeno-associated virus (AAV) into human chromosome 19 | Q35936149 | ||
Characterization of cell lines that inducibly express the adeno-associated virus Rep proteins | Q36624044 | ||
In vitro replication of adeno-associated virus DNA. | Q36627393 | ||
Efficient gene transfer into nondividing cells by adeno-associated virus-based vectors. | Q36634983 | ||
Colocalization of adeno-associated virus Rep and capsid proteins in the nuclei of infected cells | Q36656111 | ||
Adeno-associated virus Rep protein inhibits human immunodeficiency virus type 1 production in human cells | Q36688082 | ||
Sequences required for coordinate induction of adeno-associated virus p19 and p40 promoters by Rep protein | Q36693546 | ||
Adenovirus E1B 55-Mr polypeptide facilitates timely cytoplasmic accumulation of adeno-associated virus mRNAs. | Q36826114 | ||
Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression | Q36830429 | ||
Expression from the adeno-associated virus p5 and p19 promoters is negatively regulated in trans by the rep protein | Q36831270 | ||
Adeno-associated virus gene expression inhibits cellular transformation by heterologous genes | Q36838187 | ||
The adeno-associated virus rep gene inhibits replication of an adeno-associated virus/simian virus 40 hybrid genome in cos-7 cells | Q36866989 | ||
Positive and negative autoregulation of the adeno-associated virus type 2 genome | Q36883901 | ||
Negative and positive regulation in trans of gene expression from adeno-associated virus vectors in mammalian cells by a viral rep gene product | Q36918659 | ||
Effect of deletions in adenovirus early region 1 genes upon replication of adeno-associated virus | Q36939303 | ||
Adeno-associated viruses: an update. | Q39511024 | ||
Mutational analysis of adeno-associated virus Rep protein-mediated inhibition of heterologous and homologous promoters | Q39871566 | ||
In vitro replication of adeno-associated virus DNA: enhancement by extracts from adenovirus-infected HeLa cells | Q39875145 | ||
A novel 165-base-pair terminal repeat sequence is the sole cis requirement for the adeno-associated virus life cycle | Q39877984 | ||
The adeno-associated virus rep gene suppresses herpes simplex virus-induced DNA amplification | Q40109360 | ||
Adeno-associated virus vectors for gene therapy | Q40429008 | ||
Adenovirus and adeno-associated virus as vectors for gene therapy | Q40937700 | ||
Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressor | Q41192780 | ||
Inhibition of cellular and SV40 DNA replication by the adeno-associated virus Rep proteins | Q41368555 | ||
An improved system for packaging recombinant adeno-associated virus vectors capable of in vivo transduction. | Q41396968 | ||
Adeno-associated virus vector gene expression occurs in nondividing cells in the absence of vector DNA integration | Q41431346 | ||
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain | Q42280576 | ||
Properties of an adenovirus type 2 mutant, Ad2d/807, having a deletion near the right-hand genome terminus: Failure to help AAV replication | Q43410326 | ||
Adenovirus E1a proteins repress transcription from the SV40 early promoter | Q44991664 | ||
Long-term gene transfer in porcine myocardium after coronary infusion of an adeno-associated virus vector | Q45765859 | ||
Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector | Q45769447 | ||
Down-regulation of the human c-fos and c-myc proto-oncogene promoters by adeno-associated virus Rep78. | Q45781514 | ||
Rescue of adeno-associated virus from recombinant plasmids: gene correction within the terminal repeats of AAV. | Q45807702 | ||
Mutagenesis of an AUG codon in the adeno-associated virus rep gene: effects on viral DNA replication | Q45845078 | ||
The human cytomegalovirus major immediate early promoter can be trans-activated by adenovirus early proteins | Q64379058 | ||
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | vector-borne disease | Q2083837 |
virology | Q7215 | ||
P304 | page(s) | 5236-5243 | |
P577 | publication date | 1997-07-01 | |
P1433 | published in | Journal of Virology | Q1251128 |
P1476 | title | Role for highly regulated rep gene expression in adeno-associated virus vector production | |
P478 | volume | 71 |
Q35568505 | A 10 patient case report on the impact of plasmapheresis upon neutralizing factors against adeno-associated virus (AAV) types 1, 2, 6, and 8. |
Q35837765 | A Novel Adeno-Associated Virus-Based Genetic Vaccine Encoding the Hepatitis C Virus NS3/4 Protein Exhibits Immunogenic Properties in Mice Superior to Those of an NS3-Protein-Based Vaccine |
Q37012949 | A concept of eliminating nonhomologous recombination for scalable and safe AAV vector generation for human gene therapy |
Q40916579 | A helper virus-free packaging system for recombinant adeno-associated virus vectors |
Q40894016 | A method for the preparation of highly purified adeno-associated virus using affinity column chromatography, protease digestion and solvent extraction |
Q30483589 | A muscle-targeting peptide displayed on AAV2 improves muscle tropism on systemic delivery |
Q39685433 | A novel gene expression control system and its use in stable, high-titer 293 cell-based adeno-associated virus packaging cell lines |
Q64379647 | Activation of HIV-1-specific immune responses to an HIV-1 vaccine constructed from a replication-defective adenovirus vector using various combinations of immunization protocols |
Q33949811 | Adeno-associated virus (AAV) site-specific recombination does not require a Rep-dependent origin of replication within the AAV terminal repeat |
Q33603458 | Adeno-associated virus RNAs appear in a temporal order and their splicing is stimulated during coinfection with adenovirus |
Q27012320 | Adeno-associated virus at 50: a golden anniversary of discovery, research, and gene therapy success--a personal perspective |
Q40994121 | Adeno-associated virus expression systems for gene transfer |
Q45507049 | Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart |
Q39798744 | Adeno-associated virus site-specific integration is mediated by proteins of the nonhomologous end-joining pathway |
Q45709105 | Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo |
Q24563214 | Adeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminus |
Q27498163 | Adeno-associated virus: from defective virus to effective vector |
Q37060519 | Altered stored calcium release in skeletal myotubes deficient of triadin and junctin |
Q39928784 | An efficient rHSV-based complementation system for the production of multiple rAAV vector serotypes |
Q35020638 | Cloning of an avian adeno-associated virus (AAAV) and generation of recombinant AAAV particles |
Q97527299 | Creation of a High-Yield AAV Vector Production Platform in Suspension Cells Using a Design-of-Experiment Approach |
Q39686097 | Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity |
Q36288924 | Current issues in adeno-associated viral vector production |
Q40949297 | Efficient production of adeno-associated virus vectors using split-type helper plasmids |
Q24527221 | Efficient replication of adeno-associated virus type 2 vectors: a cis-acting element outside of the terminal repeats and a minimal size |
Q64376808 | Efficient retrograde neuronal transduction utilizing self-complementary AAV1 |
Q39582021 | Factors influencing adeno-associated virus-mediated gene transfer to human cystic fibrosis airway epithelial cells: comparison with adenovirus vectors. |
Q39682511 | Feasibility of generating adeno-associated virus packaging cell lines containing inducible adenovirus helper genes |
Q34471635 | Gene therapy for Fabry disease |
Q39550492 | Gene therapy vectors based on adeno-associated virus type 1. |
Q40874832 | High throughput production, screening and analysis of adeno-associated viral vectors |
Q40823398 | High-accuracy biodistribution analysis of adeno-associated virus variants by double barcode sequencing. |
Q40933793 | High-titer recombinant adeno-associated virus production utilizing a recombinant herpes simplex virus type I vector expressing AAV-2 Rep and Cap. |
Q39593544 | High-titer, wild-type free recombinant adeno-associated virus vector production using intron-containing helper plasmids |
Q37093483 | Identification of a Functionally Relevant Adeno-Associated Virus Rep68 Oligomeric Interface |
Q24293657 | Identification of a cytoplasmic interaction partner of the large regulatory proteins Rep78/Rep68 of adeno-associated virus type 2 (AAV-2) |
Q36114228 | Immunosuppression decreases inflammation and increases AAV6-hSERCA2a-mediated SERCA2a expression |
Q39941005 | Improved splicing of adeno-associated viral (AAV) capsid protein-supplying pre-mRNAs leads to increased recombinant AAV vector production |
Q34126901 | Improvement of the mdx mouse dystrophic phenotype by systemic in utero AAV8 delivery of a minidystrophin gene |
Q39589898 | Infectious entry pathway of adeno-associated virus and adeno-associated virus vectors |
Q45478176 | Intracellular route and biological activity of exogenously delivered Rep proteins from the adeno-associated virus type 2. |
Q39602167 | Intracellular trafficking of adeno-associated virus vectors: routing to the late endosomal compartment and proteasome degradation |
Q43890874 | Intratumoral gene therapy of malignant brain tumor in a rat model with angiostatin delivered by adeno-associated viral (AAV) vector |
Q39995051 | Intron splicing-mediated expression of AAV Rep and Cap genes and production of AAV vectors in insect cells |
Q33802149 | Kinetics of recombinant adeno-associated virus-mediated gene transfer |
Q45858191 | Long-term expression and repeated administration of AAV type 1, 2 and 5 vectors in skeletal muscle of immunocompetent adult mice |
Q43535625 | Long-term restoration of striatal L-aromatic amino acid decarboxylase activity using recombinant adeno-associated viral vector gene transfer in a rodent model of Parkinson's disease |
Q39698557 | Marker rescue of adeno-associated virus (AAV) capsid mutants: a novel approach for chimeric AAV production |
Q40290223 | Metabolic biotinylation provides a unique platform for the purification and targeting of multiple AAV vector serotypes |
Q89932125 | MicroRNA-based recombinant AAV vector assembly improves efficiency of suicide gene transfer in a murine model of lymphoma |
Q33745707 | Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats |
Q41634721 | New developments in the generation of Ad-free, high-titer rAAV gene therapy vectors |
Q44586325 | Optimization of packaging of adeno-associated virus gene therapy vectors using plasmid transfections |
Q40793707 | Optimization of recombinant adeno-associated virus production using an herpes simplex virus amplicon system |
Q33783728 | Packaging cells based on inducible gene amplification for the production of adeno-associated virus vectors |
Q45862016 | Packaging of an AAV vector encoding human acid α-glucosidase for gene therapy in glycogen storage disease type II with a modified hybrid adenovirus-AAV vector |
Q40881531 | Production and purification of recombinant adeno-associated virus |
Q40692830 | Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors |
Q34987161 | Production methods for gene transfer vectors based on adeno-associated virus serotypes |
Q39062624 | Production of adeno-associated virus (AAV) serotypes by transient transfection of HEK293 cell suspension cultures for gene delivery |
Q24523073 | Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus |
Q43190961 | Production of recombinant AAV vectors encoding insulin-like growth factor I is enhanced by interaction among AAV rep regulatory sequences |
Q34070162 | Production of recombinant adeno-associated virus |
Q40937480 | Production of recombinant adeno-associated virus vectors using a packaging cell line and a hybrid recombinant adenovirus |
Q34194223 | RGD inclusion in VP3 provides adeno-associated virus type 2 (AAV2)-based vectors with a heparan sulfate-independent cell entry mechanism |
Q30975099 | Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors |
Q91707074 | Recombinant Adeno-Associated Virus Gene Therapy in Light of Luxturna (and Zolgensma and Glybera): Where Are We, and How Did We Get Here? |
Q40746271 | Recombinant adeno-associated viral vector production using stable packaging and producer cell lines |
Q45747699 | Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield |
Q40705869 | Replication competent helper functions for recombinant AAV vector generation |
Q33784056 | Rescue and autonomous replication of adeno-associated virus type 2 genomes containing Rep-binding site mutations in the viral p5 promoter |
Q37433410 | SHP-1 as a critical regulator of Mycoplasma pneumoniae-induced inflammation in human asthmatic airway epithelial cells |
Q45140214 | SUMO-1 modification regulates the protein stability of the large regulatory protein Rep78 of adeno associated virus type 2 (AAV-2). |
Q42424876 | Separate basic region motifs within the adeno-associated virus capsid proteins are essential for infectivity and assembly |
Q40436594 | Serotype-specific replicating AAV helper constructs increase recombinant AAV type 2 vector production |
Q39580779 | Site-specific integration in mammalian cells mediated by a new hybrid baculovirus-adeno-associated virus vector. |
Q24791052 | Size does matter: overcoming the adeno-associated virus packaging limit |
Q36074134 | Stability and Safety of an AAV Vector for Treating RPGR-ORF15 X-Linked Retinitis Pigmentosa. |
Q91733514 | SubILM Injection of AAV for Gene Delivery to the Retina |
Q33617271 | Systemic delivery of AAV8 in utero results in gene expression in diaphragm and limb muscle: treatment implications for muscle disorders |
Q34080900 | Transient demyelination increases the efficiency of retrograde AAV transduction |
Q37479802 | Transient transfection methods for clinical adeno-associated viral vector production |
Q39682659 | Ubiquitination of both adeno-associated virus type 2 and 5 capsid proteins affects the transduction efficiency of recombinant vectors. |
Q35210473 | Vector design Tour de Force: integrating combinatorial and rational approaches to derive novel adeno-associated virus variants |
Q43546899 | Viral delivery of recombinant short hairpin RNAs |
Q64381642 | Viral gene delivery selectively restores feeding and prevents lethality of dopamine-deficient mice |
Q36098985 | cis effects in adeno-associated virus type 2 replication |
Q28144597 | rAAV vector-mediated sarcogylcan gene transfer in a hamster model for limb girdle muscular dystrophy |
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