Role for highly regulated rep gene expression in adeno-associated virus vector production

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Role for highly regulated rep gene expression in adeno-associated virus vector production is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.71.7.5236-5243.1997
P932PMC publication ID191759
P698PubMed publication ID9188591

P2093author name stringJ Li
R J Samulski
X Xiao
P2860cites workTranscriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A proteinQ24309481
Adenovirus E1A proteins interact with the cellular YY1 transcription factorQ24313191
Site-specific integration by adeno-associated virusQ24558738
Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNAQ24562760
Regulation of adeno-associated virus gene expression in 293 cells: control of mRNA abundance and translationQ24646629
Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectorsQ24682739
Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesisQ24684374
Selective extraction of polyoma DNA from infected mouse cell culturesQ29547500
Trans-activation of the human immunodeficiency virus long terminal repeat sequences, expressed in an adenovirus vector, by the adenovirus E1A 13S proteinQ33580416
Use of Adeno-Associated Virus as a General Transduction Vector for Mammalian CellsQ35228018
Site-specific integration by adeno-associated virus is directed by a cellular DNA sequenceQ35829692
Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vectorQ35872651
The adeno-associated virus (AAV) Rep protein acts as both a repressor and an activator to regulate AAV transcription during a productive infectionQ35876419
Analysis of recombinant adeno-associated virus packaging and requirements for rep and cap gene productsQ35877884
Targeted integration of adeno-associated virus (AAV) into human chromosome 19Q35936149
Characterization of cell lines that inducibly express the adeno-associated virus Rep proteinsQ36624044
In vitro replication of adeno-associated virus DNA.Q36627393
Efficient gene transfer into nondividing cells by adeno-associated virus-based vectors.Q36634983
Colocalization of adeno-associated virus Rep and capsid proteins in the nuclei of infected cellsQ36656111
Adeno-associated virus Rep protein inhibits human immunodeficiency virus type 1 production in human cellsQ36688082
Sequences required for coordinate induction of adeno-associated virus p19 and p40 promoters by Rep proteinQ36693546
Adenovirus E1B 55-Mr polypeptide facilitates timely cytoplasmic accumulation of adeno-associated virus mRNAs.Q36826114
Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expressionQ36830429
Expression from the adeno-associated virus p5 and p19 promoters is negatively regulated in trans by the rep proteinQ36831270
Adeno-associated virus gene expression inhibits cellular transformation by heterologous genesQ36838187
The adeno-associated virus rep gene inhibits replication of an adeno-associated virus/simian virus 40 hybrid genome in cos-7 cellsQ36866989
Positive and negative autoregulation of the adeno-associated virus type 2 genomeQ36883901
Negative and positive regulation in trans of gene expression from adeno-associated virus vectors in mammalian cells by a viral rep gene productQ36918659
Effect of deletions in adenovirus early region 1 genes upon replication of adeno-associated virusQ36939303
Adeno-associated viruses: an update.Q39511024
Mutational analysis of adeno-associated virus Rep protein-mediated inhibition of heterologous and homologous promotersQ39871566
In vitro replication of adeno-associated virus DNA: enhancement by extracts from adenovirus-infected HeLa cellsQ39875145
A novel 165-base-pair terminal repeat sequence is the sole cis requirement for the adeno-associated virus life cycleQ39877984
The adeno-associated virus rep gene suppresses herpes simplex virus-induced DNA amplificationQ40109360
Adeno-associated virus vectors for gene therapyQ40429008
Adenovirus and adeno-associated virus as vectors for gene therapyQ40937700
Blockage by adenovirus E4orf6 of transcriptional activation by the p53 tumor suppressorQ41192780
Inhibition of cellular and SV40 DNA replication by the adeno-associated virus Rep proteinsQ41368555
An improved system for packaging recombinant adeno-associated virus vectors capable of in vivo transduction.Q41396968
Adeno-associated virus vector gene expression occurs in nondividing cells in the absence of vector DNA integrationQ41431346
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brainQ42280576
Properties of an adenovirus type 2 mutant, Ad2d/807, having a deletion near the right-hand genome terminus: Failure to help AAV replicationQ43410326
Adenovirus E1a proteins repress transcription from the SV40 early promoterQ44991664
Long-term gene transfer in porcine myocardium after coronary infusion of an adeno-associated virus vectorQ45765859
Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vectorQ45769447
Down-regulation of the human c-fos and c-myc proto-oncogene promoters by adeno-associated virus Rep78.Q45781514
Rescue of adeno-associated virus from recombinant plasmids: gene correction within the terminal repeats of AAV.Q45807702
Mutagenesis of an AUG codon in the adeno-associated virus rep gene: effects on viral DNA replicationQ45845078
The human cytomegalovirus major immediate early promoter can be trans-activated by adenovirus early proteinsQ64379058
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectvector-borne diseaseQ2083837
virologyQ7215
P304page(s)5236-5243
P577publication date1997-07-01
P1433published inJournal of VirologyQ1251128
P1476titleRole for highly regulated rep gene expression in adeno-associated virus vector production
P478volume71

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