Long-term expression and repeated administration of AAV type 1, 2 and 5 vectors in skeletal muscle of immunocompetent adult mice

scientific article published on 11 May 2006

Long-term expression and repeated administration of AAV type 1, 2 and 5 vectors in skeletal muscle of immunocompetent adult mice is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1030428417
P356DOI10.1038/SJ.GT.3302766
P698PubMed publication ID16688207
P5875ResearchGate publication ID7093532

P2093author name stringDanos O
Rivière C
Douar AM
P2860cites workSeveral log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectorsQ45873434
Sustained and complete phenotype correction of hemophilia B mice following intramuscular injection of AAV1 serotype vectorsQ45879602
Major role of local immune responses in antibody formation to factor IX in AAV gene transferQ45883516
Transient immunosuppression allows transgene expression following readministration of adeno-associated viral vectorsQ45886179
The efficient expression of intravascularly delivered DNA in rat muscleQ45887040
Discrimination between different types of human adeno-associated viruses in clinical samples by PCRQ74653195
Femoral intra-arterial injection: a tool to deliver and assess recombinant AAV constructs in rodents whole hind limbQ81364860
Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapyQ24535690
Transduction of dendritic cells by DNA viral vectors directs the immune response to transgene products in muscle fibersQ33782809
Full functional rescue of a complete muscle (TA) in dystrophic hamsters by adeno-associated virus vector-directed gene therapyQ33793572
CD40 ligand-dependent activation of cytotoxic T lymphocytes by adeno-associated virus vectors in vivo: role of immature dendritic cellsQ33810726
Immune responses to adenovirus and adeno-associated virus in humans.Q33874473
AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.Q34168942
Clades of Adeno-associated viruses are widely disseminated in human tissues.Q34193756
Two novel adeno-associated viruses from cynomolgus monkey: pseudotyping characterization of capsid proteinQ34371678
Adeno-associated viruses undergo substantial evolution in primates during natural infectionsQ35022838
Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vectorQ35872651
Gene delivery to skeletal muscle results in sustained expression and systemic delivery of a therapeutic proteinQ35943644
Safety and efficacy of factor IX gene transfer to skeletal muscle in murine and canine hemophilia B models by adeno-associated viral vector serotype 1.Q36438711
Epitope mapping of human anti-adeno-associated virus type 2 neutralizing antibodies: implications for gene therapy and virus structureQ39589248
Humoral immunity to adeno-associated virus type 2 vectors following administration to murine and nonhuman primate muscleQ39589663
Intracellular trafficking of adeno-associated virus vectors: routing to the late endosomal compartment and proteasome degradationQ39602167
Hybrid vectors based on adeno-associated virus serotypes 2 and 5 for muscle-directed gene transferQ39603323
Characterization of tissue tropism determinants of adeno-associated virus type 1.Q39700318
Role for highly regulated rep gene expression in adeno-associated virus vector productionQ39880225
Myocardial gene transfer and long-term expression following intracoronary delivery of adeno-associated virusQ40498312
Nucleotide sequencing and generation of an infectious clone of adeno-associated virus 3.Q41190212
Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector.Q41722852
Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer.Q43727676
Stable restoration of the sarcoglycan complex in dystrophic muscle perfused with histamine and a recombinant adeno-associated viral vectorQ43783192
Immune responses to recombinant adeno-associated virus vectors: putting preclinical findings into perspectiveQ44235610
Factors influencing the development of an anti-factor IX (FIX) immune response following administration of adeno-associated virus-FIX.Q44937538
Preclinical in vivo evaluation of pseudotyped adeno-associated virus vectors for liver gene therapyQ44976981
Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heartQ45507049
Efficient transduction of skeletal muscle using vectors based on adeno-associated virus serotype 6.Q45571369
Immunity to adeno-associated virus serotype 2 delivered transgenes imparted by genetic predisposition to autoimmunityQ45698037
Correction of the enzymatic and functional deficits in a model of Pompe disease using adeno-associated virus vectorsQ45732679
Factors influencing cross-presentation of non-self antigens expressed from recombinant adeno-associated virus vectorsQ45736630
Route of administration determines induction of T-cell-independent humoral responses to adeno-associated virus vectors.Q45741128
Improved adeno-associated virus vector production with transfection of a single helper adenovirus gene, E4orf6.Q45741130
Update on the prevalence of serum antibodies (IgG and IgM) to adeno-associated virus (AAV).Q45747007
Recombinant adeno-associated virus for muscle directed gene therapyQ45764433
Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administrationQ45862335
Erythropoietin gene therapy leads to autoimmune anemia in macaquesQ45871284
Autoimmune anemia in macaques following erythropoietin gene therapyQ45871935
P433issue17
P304page(s)1300-1308
P577publication date2006-05-11
P1433published inGene TherapyQ15763095
P1476titleLong-term expression and repeated administration of AAV type 1, 2 and 5 vectors in skeletal muscle of immunocompetent adult mice
P478volume13

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cites work (P2860)
Q35568505A 10 patient case report on the impact of plasmapheresis upon neutralizing factors against adeno-associated virus (AAV) types 1, 2, 6, and 8.
Q33432320A comparison of synthetic oligodeoxynucleotides, DNA fragments and AAV-1 for targeted episomal and chromosomal gene repair
Q34814931A dystrophic muscle broadens the contribution and activation of immune cells reacting to rAAV gene transfer
Q33659389AAV's anatomy: roadmap for optimizing vectors for translational success
Q40334450AAV-mediated delivery of optogenetic constructs to the macaque brain triggers humoral immune responses
Q36708300AAV-mediated gene transfer for retinal diseases
Q35204876AAV-mediated in vivo knockdown of luciferase using combinatorial RNAi and U1i.
Q41655580AAVrh.10 immunogenicity in mice and humans. Relevance of antibody cross-reactivity in human gene therapy.
Q33601446Actin scaffolding by clathrin heavy chain is required for skeletal muscle sarcomere organization
Q35080025Adeno-associated viral vector serotype 5 poorly transduces liver in rat models
Q30885494Adeno-associated viral vectors and their redirection to cell-type specific receptors
Q34656049Advances in gene therapy for movement disorders.
Q47778748Allele-specific silencing therapy for Dynamin 2-related dominant centronuclear myopathy
Q37412239Biological gene delivery vehicles: beyond viral vectors
Q37581545Cell based therapy for Duchenne muscular dystrophy
Q33713259Comparative study of anti-hepatitis B virus RNA interference by double-stranded adeno-associated virus serotypes 7, 8, and 9.
Q39044467Comparison of Serum rAAV Serotype-Specific Antibodies in Patients with Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, Inclusion Body Myositis, or GNE Myopathy
Q33832790Comparison of adeno-associated virus pseudotype 1, 2, and 8 vectors administered by intramuscular injection in the treatment of murine phenylketonuria
Q30493438DHPR alpha1S subunit controls skeletal muscle mass and morphogenesis.
Q33296224Designer gene delivery vectors: molecular engineering and evolution of adeno-associated viral vectors for enhanced gene transfer
Q38069585Development of Novel Recombinant AAV Vectors and Strategies for the Potential Gene Therapy of Hemophilia
Q30152887Development of Patient-specific AAV Vectors After Neutralizing Antibody Selection for Enhanced Muscle Gene Transfer
Q39015003Dysferlin rescue by spliceosome-mediated pre-mRNA trans-splicing targeting introns harbouring weakly defined 3' splice sites
Q37226783Effect of vascular endothelial growth factor gene therapy on post-traumatic peripheral nerve regeneration and denervation-related muscle atrophy
Q45872187Effect of viral dose on neutralizing antibody response and transgene expression after AAV1 vector re-administration in mice
Q59360867Efficient Delivery of Human Cytomegalovirus T Cell Antigens by Attenuated Sendai Virus Vectors
Q39998139Efficient gene transfer in skeletal muscle with AAV-derived bicistronic vector using the FGF-1 IRES.
Q92635178Emerging Concepts and Challenges in Rheumatoid Arthritis Gene Therapy
Q33728191Establishment of an AAV Reverse Infection-Based Array
Q40274940Ex vivo serotype-specific transduction of equine joint tissue by self-complementary adeno-associated viral vectors
Q33713881Expression of neprilysin in skeletal muscle reduces amyloid burden in a transgenic mouse model of Alzheimer disease
Q40212331Gene Delivery of Activated Factor VII Using Alternative Adeno-Associated Virus Serotype Improves Hemostasis in Hemophiliac Mice with FVIII Inhibitors and Adeno-Associated Virus Neutralizing Antibodies
Q34180144Gene Therapy for Muscular Dystrophies: Progress and Challenges
Q34566454Gene replacement therapies for duchenne muscular dystrophy using adeno-associated viral vectors
Q91972798Gene therapy for progressive familial intrahepatic cholestasis type 3 in a clinically relevant mouse model
Q38016275Gene therapy for the treatment of chronic peripheral nervous system pain
Q81897639Growth inhibition of an established A431 xenograft tumor by a full-length anti-EGFR antibody following gene delivery by AAV
Q39465145High-Density Recombinant Adeno-Associated Viral Particles are Competent Vectors for In Vivo Transduction
Q39890263Highly efficient transduction of human plasmacytoid dendritic cells without phenotypic and functional maturation.
Q35513407Immune Responses to rAAV6: The Influence of Canine Parvovirus Vaccination and Neonatal Administration of Viral Vector
Q37127246Immunity to adeno-associated virus vectors in animals and humans: a continued challenge
Q90000829Immunoadsorption enables successful rAAV5-mediated repeated hepatic gene delivery in nonhuman primates
Q34237002Impaired adaptive response to mechanical overloading in dystrophic skeletal muscle
Q36315561Lack of repeat transduction by recombinant adeno-associated virus type 5/5 vectors in the mouse airway
Q46666393Long-Term PEDF Release in Rat Iris and Retinal Epithelial Cells after Sleeping Beauty Transposon-Mediated Gene Delivery.
Q45869991Long-term VEGF-A expression promotes aberrant angiogenesis and fibrosis in skeletal muscle
Q45361267Long-term functional adeno-associated virus-microdystrophin expression in the dystrophic CXMDj dog.
Q37601170Long-term transduction of miniature pig parotid glands using serotype 2 adeno-associated viral vectors
Q40168483Major subsets of human dendritic cells are efficiently transduced by self-complementary adeno-associated virus vectors 1 and 2.
Q40055959Muscle Gene Therapy for Hemophilia.
Q36142477MyD88 signaling in B cells regulates the production of Th1-dependent antibodies to AAV
Q42217395Neutralizing antibodies against AAV2, AAV5 and AAV8 in healthy and HIV-1-infected subjects in China: implications for gene therapy using AAV vectors
Q36174173New vectors and strategies for cardiovascular gene therapy
Q42204796Pancreatic transduction by helper-dependent adenoviral vectors via intraductal delivery.
Q27013613Perspectives of stem cell therapy in Duchenne muscular dystrophy
Q27324340Predictors of hepatitis B cure using gene therapy to deliver DNA cleavage enzymes: a mathematical modeling approach
Q37011150Priming with rAAV encoding RBD of SARS-CoV S protein and boosting with RBD-specific peptides for T cell epitopes elevated humoral and cellular immune responses against SARS-CoV infection.
Q36469478Proinsulin slows retinal degeneration and vision loss in the P23H rat model of retinitis pigmentosa
Q40063676Prolonged susceptibility to antibody-mediated neutralization for adeno-associated vectors targeted to the liver
Q37621530Promise and problems associated with the use of recombinant AAV for the delivery of anti-HIV antibodies
Q41876346Promoterless gene targeting without nucleases rescues lethality of a Crigler-Najjar syndrome mouse model
Q30519561Protein-anchoring strategy for delivering acetylcholinesterase to the neuromuscular junction
Q28386583Recombinant adeno-associated viral (rAAV) vectors mediate efficient gene transduction in cultured neonatal and adult microglia
Q37325074Reprogramming the Dynamin 2 mRNA by Spliceosome-mediated RNA Trans-splicing
Q36757156Robust Long-term Transduction of Common Marmoset Neuromuscular Tissue With rAAV1 and rAAV9.
Q54457954Safety and Efficacy of Regional Intravenous (RI) Versus Intramuscular (IM) Delivery of rAAV1 and rAAV8 to Nonhuman Primate Skeletal Muscle.
Q38168940Safety profile of recombinant adeno-associated viral vectors: focus on alipogene tiparvovec (Glybera®).
Q36756695Serotype-specific Binding Properties and Nanoparticle Characteristics Contribute to the Immunogenicity of rAAV1 Vectors
Q36171820Single amino acid modification of adeno-associated virus capsid changes transduction and humoral immune profiles
Q35511648Specific binding of collagen Q to the neuromuscular junction is exploited to cure congenital myasthenia and to explore bases of myasthenia gravis
Q33739804Subretinal delivery of adeno-associated virus serotype 2 results in minimal immune responses that allow repeat vector administration in immunocompetent mice.
Q40166892Successful Repeated Hepatic Gene Delivery in Mice and Non-human Primates Achieved by Sequential Administration of AAV5ch and AAV1.
Q93190169Temporary Reduction of Membrane CD4 with the Antioxidant MnTBAP Is Sufficient to Prevent Immune Responses Induced by Gene Transfer
Q39126011The prevalence of neutralizing antibodies against AAV serotype 1 in healthy subjects in China: implications for gene therapy and vaccines using AAV1 vector
Q36549699Therapeutic restoration of dystrophin expression in Duchenne muscular dystrophy.
Q34233343Transduction of the inner mouse retina using AAVrh8 and AAVrh10 via intravitreal injection
Q40144395Transgene persistence and cell turnover in the diarthrodial joint: implications for gene therapy of chronic joint diseases
Q53775896Transient immunomodulation allows repeated injections of AAV1 and correction of muscular dystrophy in multiple muscles.
Q34127579Translating Sleeping Beauty transposition into cellular therapies: victories and challenges
Q92649142Viral-Mediated Optogenetic Stimulation of Peripheral Motor Nerves in Non-human Primates
Q36690402Viral-mediated expression of desmin mutants to create mouse models of myofibrillar myopathy
Q40168295X-chromosome linked inhibitor of apoptosis protein inhibits muscle proteolysis in insulin-deficient mice

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