Cell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F.

scientific article published on July 1993

Cell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.13.7.3975
P932PMC publication ID359943
P698PubMed publication ID8321204

P2093author name stringLivingston DM
DeCaprio JA
Chittenden T
P2860cites workHuman DNA polymerase alpha gene: sequences controlling expression in cycling and serum-stimulated cellsQ24603946
Eukaryotic transcriptional regulatory proteinsQ29618290
E2F: a link between the Rb tumor suppressor protein and viral oncoproteinsQ29618375
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like propertiesQ29620009
A cDNA encoding a pRB-binding protein with properties of the transcription factor E2FQ29620241
The E2F transcription factor is a cellular target for the RB proteinQ29620422
cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.Q31117684
E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factorQ33856709
Adenovirus E1a prevents the retinoblastoma gene product from repressing the activity of a cellular transcription factorQ33938069
Cellular targets for transformation by the adenovirus E1A proteinsQ34438094
Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene controlQ34611866
Role of E2F transcription factor in E1A-mediated trans activation of cellular genesQ36700904
The adenovirus-inducible factor E2F stimulates transcription after specific DNA bindingQ36765954
Transcription factor E2F is required for efficient expression of the hamster dihydrofolate reductase gene in vitro and in vivoQ36795598
Genetic analysis of the adenovirus E4 6/7 trans activator: interaction with E2F and induction of a stable DNA-protein complex are critical for activityQ36798136
The adenovirus E4 17-kilodalton protein complexes with the cellular transcription factor E2F, altering its DNA-binding properties and stimulating E1A-independent accumulation of E2 mRNA.Q36806116
Activation of the E2F transcription factor in adenovirus-infected cells involves E1A-dependent stimulation of DNA-binding activity and induction of cooperative binding mediated by an E4 gene productQ36807014
Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 geneQ36821079
The HIP1 binding site is required for growth regulation of the dihydrofolate reductase gene promoterQ36962702
Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene productQ37016112
Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct mannerQ38325589
Association of cdk2 Kinase with the Transcription Factor E2F During S PhaseQ38330343
The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated mannerQ38331104
Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F.Q38331115
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding proteinQ38334727
The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2FQ38334818
A role for the adenovirus inducible E2F transcription factor in a proliferation dependent signal transduction pathwayQ38340261
Nuclear factor E2F mediates basic transcription and trans-activation by E1a of the human MYC promoterQ38344934
Interactions of the p107 and Rb proteins with E2F during the cell proliferation responseQ40872245
Promoter interaction of the E1A-inducible factor E2F and its potential role in the formation of a multi-component complexQ41345323
Cell cycle regulation of the human cdc2 geneQ41523467
Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2FQ41591490
Binding of the human E2F transcription factor to the retinoblastoma protein but not to cyclin A is abolished in HPV-16-immortalized cellsQ41607043
Retinoblastoma protein switches the E2F site from positive to negative elementQ41613404
Identification of a growth suppression domain within the retinoblastoma gene productQ41619792
A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex.Q41644025
Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexesQ41677093
Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A.Q41678631
Adenovirus E1A proteins can dissociate heteromeric complexes involving the E2F transcription factor: a novel mechanism for E1A trans-activationQ41724590
The adenovirus early region 4 open reading frame 6/7 protein regulates the DNA binding activity of the cellular transcription factor, E2F, through a direct complexQ42641126
Human cyclin A and the retinoblastoma protein interact with similar but distinguishable sequences in the adenovirus E1A gene productQ44204889
The adenovirus EIIA enhancer. Analysis of regulatory sequences and changes in binding activity of ATF and EIIF following adenovirus infectionQ44236899
Identification of a cellular transcription factor involved in E1A trans-activationQ48366187
The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2FQ52162406
Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factorQ52480364
Tumor suppressor genesQ68183482
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)3975-3983
P577publication date1993-07-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleCell cycle analysis of E2F in primary human T cells reveals novel E2F complexes and biochemically distinct forms of free E2F.
P478volume13

Reverse relations

cites work (P2860)
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Q41118589Activity of the retinoblastoma family proteins, pRB, p107, and p130, during cellular proliferation and differentiation
Q77145127Antisense Nucleic Acids Targeted to the Thymidylate Synthase (TS) mRNA Translation Start Site Stimulate TS Gene Transcription
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Q34208439Characterization of the deoxycytidine kinase promoter in human lymphoblast cell lines
Q36647938Cloning, chromosomal location, and characterization of mouse E2F1
Q24607335Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation
Q24594865DP-1: a cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for recognition by pRb and the adenovirus E4 orf 6/7 protein
Q24643965E2F Activity Is Regulated by Cell Cycle-Dependent Changes in Subcellular Localization
Q24650515E2F-4 switches from p130 to p107 and pRB in response to cell cycle reentry
Q24652329E2F-5, a new E2F family member that interacts with p130 in vivo
Q38311100HPV16 E7 oncoprotein deregulates B-myb expression: correlation with targeting of p107/E2F complexes
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