Interferon-beta gene therapy inhibits tumor formation and causes regression of established tumors in immune-deficient mice

scientific article published on November 1998

Interferon-beta gene therapy inhibits tumor formation and causes regression of established tumors in immune-deficient mice is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1998PNAS...9514411Q
P356DOI10.1073/PNAS.95.24.14411
P932PMC publication ID24387
P698PubMed publication ID9826714
P5875ResearchGate publication ID13459447

P2093author name stringJ M Wilson
A Davis
X Q Qin
N Tao
P Moy
J Barsoum
S Fawell
A Dergay
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Interferon-alpha gene therapy for cancer: retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene delivery in murine tumor modelsQ45884874
Suppression of tumorigenicity and metastasis in murine UV-2237 fibrosarcoma cells by infection with a retroviral vector harboring the interferon-beta geneQ45887885
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Microvascular injury in pathogenesis of interferon-induced necrosis of subcutaneous tumors in mice.Q52488991
The human interferon alpha-receptor protein confers differential responses to human interferon-beta versus interferon-alpha subtypes in mouse and hamster cell transfectants.Q54200731
Inhibition of angiogenesis by interferons: effects on tumor- and lymphocyte-induced vascular responses.Q54400192
Various human interferon a subclasses cross-react with common receptors: Their binding affinities correlate with their specific biological activitiesQ70188498
Alpha 1-interferon gene transfer into metastatic Friend leukemia cells abrogated tumorigenicity in immunocompetent mice: antitumor therapy by means of interferon-producing cellsQ70577067
The neglected role of type I interferon in the T-cell response: implications for its clinical useQ71475326
Pharmacokinetics and pharmacodynamics of recombinant human interferon-beta in healthy male volunteersQ71763735
Pharmacodynamics of recombinant IFN-beta during long-term treatment of malignant melanomaQ71763737
IFN-alpha 1 gene transfection completely abolishes the tumorigenicity of murine B16 melanoma cells in allogeneic DBA/2 mice and decreases their tumorigenicity in syngeneic C57BL/6 miceQ72427870
Injection of irradiated b16 melanoma genetically-modified to secrete IFN-alpha causes regression of an established tumorQ84066152
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectgene therapyQ213901
P304page(s)14411-14416
P577publication date1998-11-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleInterferon-beta gene therapy inhibits tumor formation and causes regression of established tumors in immune-deficient mice
P478volume95

Reverse relations

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