review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1152/PHYSIOL.00037.2006 |
P698 | PubMed publication ID | 17420300 |
P2093 | author name string | Roger J Hajjar | |
Yoshiaki Kawase | |||
Hung Ly | |||
Ryuichi Yoneyama | |||
P2860 | cites work | Restoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2a | Q22010899 |
Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics | Q28141424 | ||
Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease | Q28143064 | ||
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1 | Q28210584 | ||
Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis | Q28213353 | ||
Cardiac adenoviral S100A1 gene delivery rescues failing myocardium | Q28296403 | ||
Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failure | Q28354203 | ||
PKC-alpha regulates cardiac contractility and propensity toward heart failure | Q28589911 | ||
Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response | Q29619095 | ||
S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles | Q29620465 | ||
Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease: anesthetic management and results | Q31767833 | ||
Phosphodiesterase inhibitor-mediated potentiation of adenovirus delivery to myocardium | Q31952673 | ||
beta-adrenergic receptor blockade in chronic heart failure | Q33831388 | ||
AAV vectors: is clinical success on the horizon? | Q33840994 | ||
Prospects for gene therapy for heart failure | Q33881236 | ||
In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction | Q33936885 | ||
Decreased efficiency of adenovirus-mediated gene transfer in aging cardiomyocytes | Q34074815 | ||
Adeno-associated virus vectors for gene therapy: more pros than cons? | Q34080580 | ||
Catheter-based antegrade intracoronary viral gene delivery with coronary venous blockade | Q34191737 | ||
Altered beta-adrenergic receptor gene regulation and signaling in chronic heart failure | Q34245088 | ||
Nonviral vectors in the new millennium: delivery barriers in gene transfer | Q34270234 | ||
Type 1 phosphatase, a negative regulator of cardiac function | Q34281889 | ||
Assessment of risks associated with cardiovascular gene therapy in human subjects | Q34353818 | ||
Myocardial gene therapy | Q34503413 | ||
Nucleic acid based strategies as potential therapeutic tools: mechanistic considerations and implications to restenosis. | Q34542759 | ||
VEGF gene delivery for treatment of ischemic cardiovascular disease | Q34635640 | ||
Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8. | Q35025591 | ||
Molecular enhancement of porcine cardiac chronotropy | Q35381580 | ||
Genetic, cellular and immune approaches to disease therapy: past and future | Q35647868 | ||
Modulation of ventricular function through gene transfer in vivo | Q36067860 | ||
Ultrarapid, highly efficient viral gene transfer to the heart | Q36144261 | ||
Mechanisms of disease: beta-adrenergic receptors--alterations in signal transduction and pharmacogenomics in heart failure | Q36304375 | ||
Chronic phospholamban inhibition prevents progressive cardiac dysfunction and pathological remodeling after infarction in rats. | Q36441343 | ||
Interferon-beta gene therapy inhibits tumor formation and causes regression of established tumors in immune-deficient mice | Q36735680 | ||
Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling | Q39752687 | ||
'Advanced' generation lentiviruses as efficient vectors for cardiomyocyte gene transduction in vitro and in vivo. | Q40655750 | ||
A stable system for the high-titer production of multiply attenuated lentiviral vectors | Q40860697 | ||
Gene transfer by adeno-associated virus vectors into the central nervous system | Q41450710 | ||
In vivo gene transfer: a biological tool | Q41500672 | ||
High-efficiency, long-term cardiac expression of foreign genes in living mouse embryos and neonates. | Q41714490 | ||
Effects of adeno-associated virus DNA hairpin structure on recombination | Q42755152 | ||
Self-complementary adeno-associated virus serotype 2 vector: global distribution and broad dispersion of AAV-mediated transgene expression in mouse brain | Q44686125 | ||
Development of a novel fusogenic viral liposome system (HVJ-liposomes) and its applications to the treatment of acquired diseases | Q44811368 | ||
Direct intramuscular injection with recombinant AAV vectors results in sustained expression in a dog model of hemophilia | Q45060641 | ||
SERCA2A overexpression decreases the incidence of aftercontractions in adult rabbit ventricular myocytes | Q45142538 | ||
Enhancement of adenoviral gene transfer to adult rat cardiomyocytes in vivo by immobilization and ultrasound treatment of the heart. | Q45164875 | ||
Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart | Q45507049 | ||
Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo | Q45709105 | ||
Adeno-associated virus (AAV) vector antisense gene transfer in vivo decreases GABA(A) alpha1 containing receptors and increases inferior collicular seizure sensitivity | Q45762593 | ||
In vivo gene transfection of human endothelial cell nitric oxide synthase in cardiomyocytes causes apoptosis-like cell death. Identification using Sendai virus-coated liposomes | Q45762805 | ||
Gene therapy of Fanconi anemia: preclinical efficacy using lentiviral vectors. | Q45855123 | ||
Gene delivery to the myocardium by intrapericardial injection. | Q45862161 | ||
In vivo high-efficiency transcoronary gene delivery and Cre-LoxP gene switching in the adult mouse heart | Q45865309 | ||
Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins | Q45865601 | ||
Focal modification of electrical conduction in the heart by viral gene transfer | Q45872810 | ||
Sustained whole-body functional rescue in congestive heart failure and muscular dystrophy hamsters by systemic gene transfer | Q45887681 | ||
Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery | Q45888008 | ||
Acceleration of widespread adenoviral gene transfer to intact rabbit hearts by coronary perfusion with low calcium and serotonin | Q45889788 | ||
Bioartificial sinus node constructed via in vivo gene transfer of an engineered pacemaker HCN Channel reduces the dependence on electronic pacemaker in a sick-sinus syndrome model | Q46213607 | ||
Altered calcium handling is critically involved in the cardiotoxic effects of chronic beta-adrenergic stimulation. | Q51033467 | ||
Robust Adenoviral and Adeno-Associated Viral Gene Transfer to the In Vivo Murine Heart | Q58198543 | ||
P921 | main subject | heart failure | Q181754 |
gene therapy | Q213901 | ||
P304 | page(s) | 81-96 | |
P577 | publication date | 2007-04-01 | |
P1433 | published in | Physiology | Q1091804 |
P1476 | title | Gene therapy in the treatment of heart failure | |
P478 | volume | 22 |
Q37766138 | Advances in gene-based therapy for heart failure |
Q37802459 | Anti-apoptosis and cell survival: A review |
Q34195822 | Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure |
Q37364786 | Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial. |
Q38820937 | Cardiac gene therapy: are we there yet? |
Q33832137 | Cardiac gene therapy: optimization of gene delivery techniques in vivo |
Q37880858 | Chronic heart failure: current evidence, challenges to therapy, and future directions |
Q36931967 | Current strategies for myocardial gene delivery |
Q42119381 | ERK1/2 pathway regulates coxsackie and adenovirus receptor expression in mouse cardiac stem cells |
Q58612995 | Enhancing atrial specific gene expression using a calsequestrin cis-regulatory module 4 with a sarcolipin promoter |
Q40445275 | Gene Delivery for the Generation of Bioartificial Pacemaker |
Q36617570 | Gene targeting in ischemic heart disease and failure: translational and clinical studies |
Q45884822 | Gene therapy for cardiomyocytes, a heart beat away |
Q38016715 | Gene- and cell-based bio-artificial pacemaker: what basic and translational lessons have we learned? |
Q37266791 | Herpesvirus-mediated delivery of a genetically encoded fluorescent Ca(2+) sensor to canine cardiomyocytes. |
Q36882651 | In vivo cardiac myosin binding protein C gene transfer rescues myofilament contractile dysfunction in cardiac myosin binding protein C null mice |
Q45886178 | Intramyocardial injection of SERCA2a-expressing lentivirus improves myocardial function in doxorubicin-induced heart failure |
Q47135870 | Intramyocardial injection of thioredoxin 2-expressing lentivirus alleviates myocardial ischemia-reperfusion injury in rats |
Q37989402 | Lentiviral vectors and cardiovascular diseases: a genetic tool for manipulating cardiomyocyte differentiation and function |
Q37294704 | MicroRNAs as a therapeutic target for cardiovascular diseases |
Q26823061 | Model-specific selection of molecular targets for heart failure gene therapy |
Q37792416 | Novel Therapies in Childhood Heart Failure: Today and Tomorrow |
Q40910862 | SERCA2a gene therapy for heart failure: ready for primetime? |
Q57288455 | The DWORF micropeptide enhances contractility and prevents heart failure in a mouse model of dilated cardiomyopathy |
Q36458906 | The Use of Gene Therapy for Ablation of Atrial Fibrillation |