Gene therapy in the treatment of heart failure

scientific article published on April 2007

Gene therapy in the treatment of heart failure is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1152/PHYSIOL.00037.2006
P698PubMed publication ID17420300

P2093author name stringRoger J Hajjar
Yoshiaki Kawase
Hung Ly
Ryuichi Yoneyama
P2860cites workRestoration of contractile function in isolated cardiomyocytes from failing human hearts by gene transfer of SERCA2aQ22010899
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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1Q28210584
Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesisQ28213353
Cardiac adenoviral S100A1 gene delivery rescues failing myocardiumQ28296403
Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failureQ28354203
PKC-alpha regulates cardiac contractility and propensity toward heart failureQ28589911
Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune responseQ29619095
S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional rolesQ29620465
Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease: anesthetic management and resultsQ31767833
Phosphodiesterase inhibitor-mediated potentiation of adenovirus delivery to myocardiumQ31952673
beta-adrenergic receptor blockade in chronic heart failureQ33831388
AAV vectors: is clinical success on the horizon?Q33840994
Prospects for gene therapy for heart failureQ33881236
In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunctionQ33936885
Decreased efficiency of adenovirus-mediated gene transfer in aging cardiomyocytesQ34074815
Adeno-associated virus vectors for gene therapy: more pros than cons?Q34080580
Catheter-based antegrade intracoronary viral gene delivery with coronary venous blockadeQ34191737
Altered beta-adrenergic receptor gene regulation and signaling in chronic heart failureQ34245088
Nonviral vectors in the new millennium: delivery barriers in gene transferQ34270234
Type 1 phosphatase, a negative regulator of cardiac functionQ34281889
Assessment of risks associated with cardiovascular gene therapy in human subjectsQ34353818
Myocardial gene therapyQ34503413
Nucleic acid based strategies as potential therapeutic tools: mechanistic considerations and implications to restenosis.Q34542759
VEGF gene delivery for treatment of ischemic cardiovascular diseaseQ34635640
Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8.Q35025591
Molecular enhancement of porcine cardiac chronotropyQ35381580
Genetic, cellular and immune approaches to disease therapy: past and futureQ35647868
Modulation of ventricular function through gene transfer in vivoQ36067860
Ultrarapid, highly efficient viral gene transfer to the heartQ36144261
Mechanisms of disease: beta-adrenergic receptors--alterations in signal transduction and pharmacogenomics in heart failureQ36304375
Chronic phospholamban inhibition prevents progressive cardiac dysfunction and pathological remodeling after infarction in rats.Q36441343
Interferon-beta gene therapy inhibits tumor formation and causes regression of established tumors in immune-deficient miceQ36735680
Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signalingQ39752687
'Advanced' generation lentiviruses as efficient vectors for cardiomyocyte gene transduction in vitro and in vivo.Q40655750
A stable system for the high-titer production of multiply attenuated lentiviral vectorsQ40860697
Gene transfer by adeno-associated virus vectors into the central nervous systemQ41450710
In vivo gene transfer: a biological toolQ41500672
High-efficiency, long-term cardiac expression of foreign genes in living mouse embryos and neonates.Q41714490
Effects of adeno-associated virus DNA hairpin structure on recombinationQ42755152
Self-complementary adeno-associated virus serotype 2 vector: global distribution and broad dispersion of AAV-mediated transgene expression in mouse brainQ44686125
Development of a novel fusogenic viral liposome system (HVJ-liposomes) and its applications to the treatment of acquired diseasesQ44811368
Direct intramuscular injection with recombinant AAV vectors results in sustained expression in a dog model of hemophiliaQ45060641
SERCA2A overexpression decreases the incidence of aftercontractions in adult rabbit ventricular myocytesQ45142538
Enhancement of adenoviral gene transfer to adult rat cardiomyocytes in vivo by immobilization and ultrasound treatment of the heart.Q45164875
Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heartQ45507049
Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivoQ45709105
Adeno-associated virus (AAV) vector antisense gene transfer in vivo decreases GABA(A) alpha1 containing receptors and increases inferior collicular seizure sensitivityQ45762593
In vivo gene transfection of human endothelial cell nitric oxide synthase in cardiomyocytes causes apoptosis-like cell death. Identification using Sendai virus-coated liposomesQ45762805
Gene therapy of Fanconi anemia: preclinical efficacy using lentiviral vectors.Q45855123
Gene delivery to the myocardium by intrapericardial injection.Q45862161
In vivo high-efficiency transcoronary gene delivery and Cre-LoxP gene switching in the adult mouse heartQ45865309
Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veinsQ45865601
Focal modification of electrical conduction in the heart by viral gene transferQ45872810
Sustained whole-body functional rescue in congestive heart failure and muscular dystrophy hamsters by systemic gene transferQ45887681
Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene deliveryQ45888008
Acceleration of widespread adenoviral gene transfer to intact rabbit hearts by coronary perfusion with low calcium and serotoninQ45889788
Bioartificial sinus node constructed via in vivo gene transfer of an engineered pacemaker HCN Channel reduces the dependence on electronic pacemaker in a sick-sinus syndrome modelQ46213607
Altered calcium handling is critically involved in the cardiotoxic effects of chronic beta-adrenergic stimulation.Q51033467
Robust Adenoviral and Adeno-Associated Viral Gene Transfer to the In Vivo Murine HeartQ58198543
P921main subjectheart failureQ181754
gene therapyQ213901
P304page(s)81-96
P577publication date2007-04-01
P1433published inPhysiologyQ1091804
P1476titleGene therapy in the treatment of heart failure
P478volume22

Reverse relations

cites work (P2860)
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