Gene transfer by adeno-associated virus vectors into the central nervous system

scientific article published on March 1997

Gene transfer by adeno-associated virus vectors into the central nervous system is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1006/EXNR.1996.6396
P698PubMed publication ID9126160

P2093author name stringLi J
Samulski RJ
Xiao X
McCown TJ
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectvector-borne diseaseQ2083837
P304page(s)113-124
P577publication date1997-03-01
P1433published inExperimental NeurologyQ5421127
P1476titleGene transfer by adeno-associated virus vectors into the central nervous system
P478volume144

Reverse relations

cites work (P2860)
Q92856615A New Projection From the Deep Cerebellar Nuclei to the Hippocampus via the Ventrolateral and Laterodorsal Thalamus in Mice
Q36242844A Single Vector Platform for High-Level Gene Transduction of Central Neurons: Adeno-Associated Virus Vector Equipped with the Tet-Off System
Q33799084A chimeric protein containing the N terminus of the adeno-associated virus Rep protein recognizes its target site in an in vivo assay
Q45752547A neuron-specific gene transfer by a recombinant defective Sindbis virus
Q39893541AAV serotype 2/1-mediated gene delivery of anti-inflammatory interleukin-10 enhances neurogenesis and cognitive function in APP+PS1 mice
Q37260178AAV1/2-mediated CNS gene delivery of dominant-negative CCL2 mutant suppresses gliosis, beta-amyloidosis, and learning impairment of APP/PS1 mice
Q45884480Activation of the extracellular signal-regulated kinase 1/2 pathway by AAV gene transfer protects retinal ganglion cells in glaucoma
Q30885494Adeno-associated viral vectors and their redirection to cell-type specific receptors
Q48586865Adeno-associated viral vectors for anterograde axonal tracing with fluorescent proteins in nontransgenic and cre driver mice
Q35216648Adeno-associated viral vectors.
Q40994121Adeno-associated virus expression systems for gene transfer
Q34063628Adeno-associated virus serotypes 1, 8, and 9 share conserved mechanisms for anterograde and retrograde axonal transport.
Q45728411Adeno-associated virus vector expressing nerve growth factor enhances cholinergic axonal sprouting after cortical injury in rats.
Q45740016Adeno-associated virus vector-mediated gene transfer to somatic cells in the central nervous system
Q45457280Adeno-associated virus-mediated gene transfer to hair cells and support cells of the murine cochlea
Q28141743Adenoviral and adeno-associated viral transfer of genes to the peripheral nervous system
Q37766138Advances in gene-based therapy for heart failure
Q34953198Alphaviral gene transfer in neurobiology
Q47230840Cloning of a novel Apaf-1-interacting protein: a potent suppressor of apoptosis and ischemic neuronal cell death.
Q33296224Designer gene delivery vectors: molecular engineering and evolution of adeno-associated viral vectors for enhanced gene transfer
Q33645324Disease-inducible transgene expression from a recombinant adeno-associated virus vector in a rat arthritis model
Q24797018Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors
Q33713355Efficient intrathymic gene transfer following in situ administration of a rAAV serotype 8 vector in mice and nonhuman primates.
Q40321040Endostatin therapy reveals a U-shaped curve for antitumor activity
Q45882831Enhanced expression of glutamate decarboxylase 65 improves symptoms of rat parkinsonian models.
Q34997245Enhancement of Recombinant Adeno-Associated Virus Type 2-Mediated Transgene Expression in a Lung Epithelial Cell Line by Inhibition of the Epidermal Growth Factor Receptor
Q46386515Extracellular signal-regulated kinase 1/2 mediates survival, but not axon regeneration, of adult injured central nervous system neurons in vivo
Q35621081FGF2 gene transfer restores hippocampal functions in mouse models of Alzheimer's disease and has therapeutic implications for neurocognitive disorders
Q44686144Fibroblast growth factor-2 gene delivery stimulates axon growth by adult retinal ganglion cells after acute optic nerve injury
Q33997202Formation of AAV single stranded DNA genome from a circular plasmid in Saccharomyces cerevisiae
Q33793572Full functional rescue of a complete muscle (TA) in dystrophic hamsters by adeno-associated virus vector-directed gene therapy
Q45856156Gene therapy for inherited neurological disorders: towards therapeutic intervention in the Lesch-Nyhan syndrome.
Q30357745Gene therapy for metachromatic leukodystrophy.
Q64381800Gene therapy for rheumatoid arthritis
Q36786243Gene therapy in the treatment of heart failure
Q33534302Gene transfer to the brain: emerging therapeutic strategy in psychiatry?
Q37305249Gene transfer using bovine adeno-associated virus in the guinea pig cochlea
Q35131227Immunity to adenovirus and adeno-associated viral vectors: implications for gene therapy
Q45869654Influence of promoter and WHV post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brain
Q41884818Influences of HIF-lα on Bax/Bcl-2 and VEGF expressions in rats with spinal cord injury
Q34126428Inhibitory RNA in epilepsy: research tools and therapeutic perspectives
Q34992549Insight into the mechanism of inhibition of adeno-associated virus by the Mre11/Rad50/Nbs1 complex
Q37413701Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice
Q41713142Intraneuronal aggregate formation and cell death after viral expression of expanded polyglutamine tracts in the adult rat brain.
Q34128898Intrathecal delivery of a mutant micro-opioid receptor activated by naloxone as a possible antinociceptive paradigm.
Q33870310Involvement of cellular double-stranded DNA break binding proteins in processing of the recombinant adeno-associated virus genome.
Q37265519Large animal models of neurological disorders for gene therapy
Q24527302Latent adeno-associated virus infection elicits humoral but not cell-mediated immune responses in a nonhuman primate model
Q37378737Local knockdown of ERK2 in the adult mouse brain via adeno-associated virus-mediated RNA interference.
Q30573520Long-distance axonal transport of AAV9 is driven by dynein and kinesin-2 and is trafficked in a highly motile Rab7-positive compartment
Q33221962Long-term safety of GDNF gene delivery in the retina
Q28766660Methods, potentials, and limitations of gene delivery to regenerate central nervous system cells
Q35565452Molecular basis of Canavan's disease: from human to mouse
Q41634721New developments in the generation of Ad-free, high-titer rAAV gene therapy vectors
Q45743733Oligodendrocyte-specific gene expression in mouse brain: use of a myelin-forming cell type-specific promoter in an adeno-associated virus
Q33824969Overexpression of cyclin A inhibits augmentation of recombinant adeno-associated virus transduction by the adenovirus E4orf6 protein
Q33753300Phosphatidylserine immobilization of lentivirus for localized gene transfer
Q24523073Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus
Q34987192Promoters and regulatory elements that improve adeno-associated virus transgene expression in the brain
Q46383994Proteasome inhibition enhances AAV-mediated transgene expression in human synoviocytes in vitro and in vivo.
Q45735544Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes.
Q45007196Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system
Q91707074Recombinant Adeno-Associated Virus Gene Therapy in Light of Luxturna (and Zolgensma and Glybera): Where Are We, and How Did We Get Here?
Q36390517Recombinant Semliki Forest virus and Sindbis virus efficiently infect neurons in hippocampal slice cultures
Q45411417Recombinant adeno-associated virus preferentially transduces human, compared to mouse, synovium: implications for arthritis therapy
Q31139438Recombinant adeno-associated virus vector expressing angiostatin inhibits preretinal neovascularization in adult rats
Q34472181Recombinant adeno-associated virus vector: use for transgene expression and anterograde tract tracing in the CNS
Q33823405Repeated delivery of adeno-associated virus vectors to the rabbit airway
Q45868070Ribozyme gene therapy for autosomal dominant retinal disease.
Q34058780Ribozyme uses in retinal gene therapy.
Q42012887Several rAAV vectors efficiently cross the blood-brain barrier and transduce neurons and astrocytes in the neonatal mouse central nervous system
Q42007195Stereotaxic microinjection of viral vectors expressing Cre recombinase to study the role of target genes in cocaine conditioned place preference
Q27681034Structure of adeno-associated virus-2 in complex with neutralizing monoclonal antibody A20
Q37295510Suppression of experimental uveitis by a recombinant adeno-associated virus vector encoding interleukin-1 receptor antagonist
Q45236560Systemic mannitol-induced hyperosmolality amplifies rAAV2-mediated striatal transduction to a greater extent than local co-infusion
Q30411312Targeted delivery of brain-derived neurotrophic factor for the treatment of blindness and deafness.
Q35136635Targeting neurons of rat nucleus tractus solitarii with the gene transfer vector adeno-associated virus type 2 to up-regulate neuronal nitric oxide synthase
Q36337994The assessment of adeno-associated vectors as potential intrinsic treatments for brainstem axon regeneration
Q45420843Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and Rh10 in the mouse brain
Q45884333Transduction of human neural progenitor cells using recombinant adeno-associated viral vectors
Q34399110Treatment of GM2 gangliosidosis: past experiences, implications, and future prospects
Q43999162TrkB gene transfer protects retinal ganglion cells from axotomy-induced death in vivo.
Q36541150Tropism and toxicity of adeno-associated viral vector serotypes 1, 2, 5, 6, 7, 8, and 9 in rat neurons and glia in vitro.
Q33747865Two-photon imaging of calcium in virally transfected striate cortical neurons of behaving monkey
Q36370376Use of Adeno-Associated and Herpes Simplex Viral Vectors for In Vivo Neuronal Expression in Mice
Q41909454Use of self-complementary adeno-associated virus serotype 2 as a tracer for labeling axons: implications for axon regeneration
Q58119543Viral-vectored ribozymes as therapy for autosomal dominant retinal disease
Q39611260Widespread gene delivery and structure-specific patterns of expression in the brain after intraventricular injections of neonatal mice with an adeno-associated virus vector

Search more.