Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload-Induced Mitochondrial Dysfunction and Heart Failure.

scientific article published on 25 February 2016

Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload-Induced Mitochondrial Dysfunction and Heart Failure. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/CIRCULATIONAHA.115.020502
P932PMC publication ID4811679
P698PubMed publication ID26915633

P50authorBeth LevineQ4897570
Junichi SadoshimaQ51313947
Toshiro SaitoQ83331630
Kensuke EgashiraQ125191461
Peiyong ZhaiQ125191609
Akihiro ShirakabeQ125191749
P2093author name stringMasatoshi Nomura
Yasuhiro Maejima
Yoshiyuki Ikeda
Chiao-Po Hsu
P2860cites workThe mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathwaysQ24302411
Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondriaQ24320227
Titration of mitochondrial fusion rescues Mff-deficient cardiomyopathyQ27309059
Mechanisms of mitophagyQ27310261
Autophagy plays an essential role in mediating regression of hypertrophy during unloading of the heartQ27330210
Molecular mechanisms of mitochondrial autophagy/mitophagy in the heartQ28393192
High throughput microplate respiratory measurements using minimal quantities of isolated mitochondriaQ28479257
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stressQ28506886
Identification of a candidate therapeutic autophagy-inducing peptideQ28593490
Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell deathQ29620448
Discovery of Atg5/Atg7-independent alternative macroautophagyQ34612369
Molecular mechanisms of autophagy in the cardiovascular systemQ35037307
Mitochondrial fission and fusion factors reciprocally orchestrate mitophagic culling in mouse hearts and cultured fibroblastsQ35054529
Cardiac autophagy is a maladaptive response to hemodynamic stressQ35839989
Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathwaysQ35852737
Hrd1 and ER-Associated Protein Degradation, ERAD, are Critical Elements of the Adaptive ER Stress Response in Cardiac MyocytesQ36348263
Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarctionQ36526385
CaM kinase I alpha-induced phosphorylation of Drp1 regulates mitochondrial morphologyQ36817918
A method to measure cardiac autophagic flux in vivoQ37007826
Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2.Q37297383
Activation of NADPH oxidase 4 in the endoplasmic reticulum promotes cardiomyocyte autophagy and survival during energy stress through the protein kinase RNA-activated-like endoplasmic reticulum kinase/eukaryotic initiation factor 2α/activating transQ37608713
Mammalian target of rapamycin signaling in cardiac physiology and disease.Q37715817
A sensitive and quantitative technique for detecting autophagic events based on lysosomal deliveryQ39484588
Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac MyocytesQ41524923
Rheb is a critical regulator of autophagy during myocardial ischemia: pathophysiological implications in obesity and metabolic syndrome.Q41820920
Oxidative Stress Stimulates Autophagic Flux During Ischemia/ReperfusionQ42116691
Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.Q51057544
Endogenous Drp1 mediates mitochondrial autophagy and protects the heart against energy stressQ51313895
Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fissionQ53571110
X-ROS Signaling: Rapid Mechano-Chemo Transduction in HeartQ84919613
P433issue13
P407language of work or nameEnglishQ1860
P921main subjectheart failureQ181754
autophagyQ288322
P304page(s)1249-1263
P577publication date2016-02-25
P1433published inCirculationQ578091
P1476titleDrp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload-Induced Mitochondrial Dysfunction and Heart Failure
P478volume133

Reverse relations

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