Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors.

scientific article published on 16 May 2008

Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1039337121
P356DOI10.1186/BCR2098
P932PMC publication ID2481494
P698PubMed publication ID18485221
P5875ResearchGate publication ID5365798

P50authorDave S. HoonQ47357507
P2093author name stringEiji Sunami
Myung-Shin Sim
Sandy L Nguyen
Armando E Giuliano
Masaru Shinozaki
Anh-Thu Vu
P2860cites workEpigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppressionQ24291194
Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor geneQ24305178
Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progressionQ24316952
Molecular portraits of human breast tumoursQ28032461
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasisQ28131703
Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotypeQ28271274
The role for NES1 serine protease as a novel tumor suppressorQ28288382
Adenomatous polyposis coli (APC) gene promoter hypermethylation in primary breast cancersQ28343483
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancerQ29547699
DNA methylation of RASSF1A, HIN‐1, RAR‐β, Cyclin D2 and Twist in in situ and invasive lobular breast carcinomaQ34274795
Concordance among gene-expression-based predictors for breast cancerQ34555829
Hormone-related risk factors for breast cancer in women under age 50 years by estrogen and progesterone receptor status: results from a case-control and a case-case comparisonQ35605821
Fluctuation of HER2 expression in breast carcinomas during the menstrual cycleQ35788151
Relationship between c-erbB-2 protein product expression and response to endocrine therapy in advanced breast cancerQ35992905
Role of the Ras-association domain family 1 tumor suppressor gene in human cancersQ36113844
Advanced concepts in estrogen receptor biology and breast cancer endocrine resistance: implicated role of growth factor signaling and estrogen receptor coregulatorsQ36307445
Epigenetic information and estrogen receptor alpha expression in breast cancerQ36364262
Novel mechanisms of resistance to endocrine therapy: genomic and nongenomic considerationsQ36391473
Epigenetic therapy of cancer: past, present and futureQ36399557
Clinical trials with retinoids for breast cancer chemopreventionQ36443030
The receptor expression pattern in ductal carcinoma in situ predicts recurrenceQ36504065
DNA methylation as a therapeutic target in cancerQ36760984
Very high frequency of hypermethylated genes in breast cancer metastasis to the bone, brain, and lungQ38447859
RASSF1A suppresses the c-Jun-NH2-kinase pathway and inhibits cell cycle progressionQ40427754
Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancerQ40490715
A role for the RASSF1A tumor suppressor in the regulation of tubulin polymerization and genomic stabilityQ40543835
Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen.Q40550191
Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: a population-based study from the California cancer RegistryQ42510173
Gene expression profiling and histopathological characterization of triple-negative/basal-like breast carcinomasQ42519640
Reduction of E-cadherin expression is associated with non-lobular breast carcinomas of basal-like and triple negative phenotypeQ42523034
Epigenetic inactivation of RAS association domain family protein 1 (RASSF1A) in malignant cutaneous melanoma.Q42596171
Aberrant methylation of the adenomatous polyposis coli (APC) gene promoter 1A in breast and lung carcinomasQ43670890
Frequent epigenetic inactivation of RASSF1A in human bladder carcinoma.Q43739406
Rates for breast cancer characteristics by estrogen and progesterone receptor status in the major racial/ethnic groupsQ44121727
Risk factors for breast cancer according to estrogen and progesterone receptor statusQ44753983
Nonrandom distribution of aberrant promoter methylation of cancer-related genes in sporadic breast tumorsQ45877410
Hormone receptors do not predict the HER2/neu status in all age groups of women with an operable breast cancerQ46639338
Breast cancer DNA methylation profiles in cancer cells and tumor stroma: association with HER-2/neu status in primary breast cancer.Q46882661
Inactivation of cyclin D2 gene in prostate cancers by aberrant promoter methylation.Q47420791
Estrogen receptors: role in breast cancer.Q53595317
The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy.Q54115075
DNA hypermethylation in breast cancer and its association with clinicopathological features.Q54652899
Evaluation of oestrogen and progesterone receptor status in HER-2 positive breast carcinomas and correlation with outcomeQ56994624
Epigenetic and genetic alterations ofAPCandCDH1genes in lobular breast cancer: Relationships with abnormal E-cadherin and catenin expression and microsatellite instabilityQ57240014
Nutrition and breast cancerQ57421555
Hormonal modulation of HER-2/neu protooncogene messenger ribonucleic acid and p185 protein expression in human breast cancer cell linesQ68090333
Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hypermethylationQ73715187
Aberrant methylation of the estrogen receptor and E-cadherin 5' CpG islands increases with malignant progression in human breast cancerQ74256215
Correlation between genetic and biological aspects in primary non-metastatic breast cancers and corresponding synchronous axillary lymph node metastasisQ79886403
Hypermethylation in histologically distinct classes of breast cancerQ80787663
Breast cancer risk factors according to joint estrogen receptor and progesterone receptor statusQ81265275
Distinct hypermethylation profile of primary breast cancer is associated with sentinel lymph node metastasisQ81570140
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectestrogenQ277954
P304page(s)R46
P577publication date2008-05-16
P1433published inBreast Cancer ResearchQ2208481
P1476titleEstrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors
P478volume10

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cites work (P2860)
Q58597281A DNA Methylation-Based Test for Breast Cancer Detection in Circulating Cell-Free DNA
Q35989635Aberrant hypermethylation in primary tumours and sentinel lymph node metastases in paediatric patients with cutaneous melanoma
Q39122199Aberrant methylation of RASSF1A is associated with poor survival in Tunisian breast cancer patients
Q36061986Applicability of HIN-1, MGMT and RASSF1A promoter methylation as biomarkers for detecting field cancerization in breast cancer
Q33689442Array-Based DNA Methylation Profiling for Breast Cancer Subtype Discrimination
Q26783596Clinicopathological significance and potential drug target of CDH1 in breast cancer: a meta-analysis and literature review
Q37308097DNA methylation and breast tumor clinicopathological features: The Western New York Exposures and Breast Cancer (WEB) study
Q36583742DNA methylation and hormone receptor status in breast cancer
Q37620392DNA methylation as a biomarker in breast cancer
Q42496731Distinct patterns of promoter CpG island methylation of breast cancer subtypes are associated with stem cell phenotypes
Q28087759Emerging technologies for studying DNA methylation for the molecular diagnosis of cancer
Q42367979Epigenetic Mechanisms of Tamoxifen Resistance in Luminal Breast Cancer
Q27694612Epigenetic regulation in estrogen receptor positive breast cancer--role in treatment response
Q38012175Epigenetics of estrogen receptor-negative primary breast cancer
Q42931926Estrogen and progesterone receptor status affect genome-wide DNA methylation profile in breast cancer
Q34625392Estrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status
Q33892868Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer
Q33848807Gene promoter methylation is associated with increased mortality among women with breast cancer
Q54936274Gestational oral low-dose estradiol-17β induces altered DNA methylation of CDKN2D and PSAT1 in embryos and adult offspring.
Q33676758Growth factor receptor-bound protein-7 (Grb7) as a prognostic marker and therapeutic target in breast cancer
Q42266190Human parvovirus B19 infection leads to downregulation of thyroid, estrogen, and retinoid hormone receptor expression
Q35993199Immunohistochemical, genetic and epigenetic profiles of hereditary and triple negative breast cancers. Relevance in personalized medicine
Q36925229Inherited and acquired alterations in development of breast cancer.
Q26782613Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential
Q61814607Interplay between Epigenetics, Expression of Estrogen Receptor- α, HER2/ERBB2 and Sensitivity of Triple Negative Breast Cancer Cells to Hormonal Therapy
Q38778540Intratumor Heterogeneity in Breast Cancer
Q28269080Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology
Q35958967Methylated APC and GSTP1 genes in serum DNA correlate with the presence of circulating blood tumor cells and are associated with a more aggressive and advanced breast cancer disease.
Q54484988Methylated DNA and total DNA in serum detected by one-step methylation-specific PCR is predictive of poor prognosis for breast cancer patients.
Q39287409Methylation in promoter regions of PITX2 and RASSF1A genes in association with clinicopathological features in breast cancer patients
Q54569398Methylation status and protein expression of RASSF1A in breast cancer patients.
Q34048118Molecular subtypes of breast cancer are associated with characteristic DNA methylation patterns
Q37367387PTPRO promoter methylation is predictive of poorer outcome for HER2-positive breast cancer: indication for personalized therapy
Q53449089Promoter CpG island hypermethylation during breast cancer progression.
Q37429833Promoter Hypermethylation in Tumor Suppressing Genes p16 and FHIT and Their Relationship with Estrogen Receptor and Progesterone Receptor Status in Breast Cancer Patients from Northern India
Q37006733Quantitation of CDH1 promoter methylation in formalin-fixed paraffin-embedded tissues of breast cancer patients using differential high resolution melting analysis
Q35008011Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
Q37437350Quantitative assessment of the association between APC promoter methylation and breast cancer
Q36865048RASSF1A Promoter Methylation Levels Positively Correlate with Estrogen Receptor Expression in Breast Cancer Patients
Q53190494RASSF1A inhibits estrogen receptor alpha expression and estrogen-independent signalling: implications for breast cancer development.
Q88013658TIMP3 Promoter Methylation Represents an Epigenetic Marker of BRCA1ness Breast Cancer Tumours
Q57107038The Epigenetics of Triple-Negative and Basal-Like Breast Cancer: Current Knowledge
Q37177902The presence of circulating total DNA and methylated genes is associated with circulating tumour cells in blood from breast cancer patients
Q47146956Tumor Heterogeneity in Breast Cancer
Q37699138Unique epigenetic gene profiles define human breast cancers with poor prognosis.
Q33570282Unraveling breast cancer heterogeneity through transcriptomic and epigenomic analysis

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