Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer

scientific article

Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1040722741
P356DOI10.1186/BCR2466
P932PMC publication ID2880421
P698PubMed publication ID20056007
P5875ResearchGate publication ID40893993

P50authorAnne-Lise Børresen-DaleQ11958220
Ida R K BukholmQ114329374
Jo Anders RønnebergQ114575649
Florence BusatoQ117267002
Vessela KristensenQ37344701
Fredrik WärnbergQ38155358
Jorg TostQ41047855
Therese SørlieQ60034610
Hiroko Kato SolvangQ91221539
Jovana JovanovićQ91418504
P2093author name stringJohan Botling
Aslaug Aa Muggerud
P2860cites workValidation of reference genes for quantitative RT-PCR studies in porcine oocytes and preimplantation embryosQ21284136
PTEN: life as a tumor suppressorQ28203431
A gene hypermethylation profile of human cancerQ28213253
The epigenomics of cancerQ28289975
Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-upQ28306437
Genomic and transcriptional aberrations linked to breast cancer pathophysiologiesQ29619120
Quantitative assessment of promoter hypermethylation during breast cancer developmentQ30811494
Molecular markers in ductal carcinoma in situ of the breast.Q31135997
Gene expression profiles of human breast cancer progressionQ33186821
Progression-specific genes identified by expression profiling of matched ductal carcinomas in situ and invasive breast tumors, combining laser capture microdissection and oligonucleotide microarray analysisQ33243821
Fox's in development and diseaseQ34205134
DNA methylation of RASSF1A, HIN‐1, RAR‐β, Cyclin D2 and Twist in in situ and invasive lobular breast carcinomaQ34274795
Distinct genetic profiles in colorectal tumors with or without the CpG island methylator phenotypeQ34975498
Classification of ductal carcinoma in situ by gene expression profilingQ35605885
Frequent 7q gains in flow cytometric multiploid/hypertetraploid breast carcinomas: a study of chromosome imbalances by comparative genomic hybridisationQ35769900
p53 mutations and expression in breast carcinoma in situQ35793421
Correlation between CpG methylation profiles and hormone receptor status in breast cancersQ36393321
Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors.Q36787353
Cell type-specific DNA methylation patterns in the human breastQ36869180
The molecular journey from ductal carcinoma in situ to invasive breast cancerQ37126345
Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesisQ37268177
Hypermethylation of the ABCB1 downstream gene promoter accompanies ABCB1 gene amplification and increased expression in docetaxel-resistant MCF-7 breast tumor cellsQ39918721
Combined cDNA array comparative genomic hybridization and serial analysis of gene expression analysis of breast tumor progressionQ40291730
Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen.Q40550191
Ductal carcinoma in situ: a proposal for a new classificationQ40576913
Differential distribution of DNA methylation within the RASSF1A CpG island in breast cancerQ40626135
Full sequencing of TP53 identifies identical mutations within in situ and invasive components in breast cancer suggesting clonal evolutionQ41130119
GSTP1 promoter haplotypes affect DNA methylation levels and promoter activity in breast carcinomas.Q42439010
Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancerQ42499457
Mismatch repair genes hMLH1 and hMSH2 may not play an essential role in breast carcinogenesisQ42516388
Integrated profiling of basal and luminal breast cancers.Q42522755
MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: changes in chromatin structure induced by treatment with 5-Aza-cytidineQ44807704
Epigenetic regulation of protein phosphatase 2A (PP2A), lymphotactin (XCL1) and estrogen receptor alpha (ER) expression in human breast cancer cells.Q45232200
Nonrandom distribution of aberrant promoter methylation of cancer-related genes in sporadic breast tumorsQ45877410
In situ analyses of genome instability in breast cancerQ46051522
Role of ABCB1 and ABCC1 gene induction on survival in locally advanced breast cancerQ46172041
Selection of reference genes for quantitative real-time RT-PCR studies in mouse brain.Q46943029
Mapping of ER gene CpG island methylation-specific polymerase chain reactionQ47945083
Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers.Q53342403
Inactivation of glutathione S-transferase P1 gene by promoter hypermethylation in human neoplasiaQ53429823
Quantitative promoter hypermethylation profiles of ductal carcinoma in situ in North American and Korean women: Potential applications for diagnosisQ53530745
Methylation of E-cadherin and hMLH1 genes in Indian sporadic breast carcinomas.Q54617735
Quantification of CpG island methylation in progressive breast lesions from normal to invasive carcinomaQ57161281
p53 missense mutations in microdissected high-grade ductal carcinoma in situ of the breastQ73828802
Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCRQ73852496
Detection of RASSF1A aberrant promoter hypermethylation in sputum from chronic smokers and ductal carcinoma in situ from breast cancer patientsQ78794145
GSTP1 promoter hypermethylation is an early event in breast carcinogenesisQ80265741
Promoter methylation of the PTEN gene is a common molecular change in breast cancerQ80403566
PTEN promoter is methylated in a proportion of invasive breast cancersQ80594418
Expression of mismatch repair proteins in invasive and in situ carcinoma of the breastQ80954893
DNA methylation analysis by pyrosequencingQ81247006
P433issue1
P921main subjectbreast cancerQ128581
DNA methylationQ874745
ductal carcinomaQ5311598
P304page(s)R3
P577publication date2010-01-07
P1433published inBreast Cancer ResearchQ2208481
P1476titleFrequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer
P478volume12

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cites work (P2860)
Q58597281A DNA Methylation-Based Test for Breast Cancer Detection in Circulating Cell-Free DNA
Q34447578ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth
Q38617799All roads lead to PP2A: exploiting the therapeutic potential of this phosphatase
Q60961798Analysis of PTEN expression and promoter methylation in Uyghur patients with mild type 2 diabetes mellitus
Q34709370Assessment of DNA methylation status in early stages of breast cancer development
Q42371780Association between MGMT Promoter Methylation and Risk of Breast and Gynecologic Cancers: A Systematic Review and Meta-Analysis.
Q41012393Association of the hypermethylation status of PTEN tumor suppressor gene with the risk of breast cancer among Kurdish population from Western Iran
Q41056167BRAF mutation-specific promoter methylation of FOX genes in colorectal cancer
Q63245336CXCL12 and ADAM23 hypermethylation are associated with advanced breast cancers
Q34294336Concurrent epigenetic silencing of wnt/β-catenin pathway inhibitor genes in B cell chronic lymphocytic leukaemia.
Q36778107Copy number aberrations of genes regulating normal thymus development in thymic epithelial tumors.
Q38692509CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer.
Q64940251DNA Methylation Profiles and Their Diagnostic Utility in BC.
Q37308097DNA methylation and breast tumor clinicopathological features: The Western New York Exposures and Breast Cancer (WEB) study
Q33952447DNA methylation changes in atypical adenomatous hyperplasia, adenocarcinoma in situ, and lung adenocarcinoma.
Q36998647DNA methylation in ductal carcinoma in situ of the breast
Q35888926DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer
Q38610743Diagnostic and prognostic epigenetic biomarkers in cancer
Q47400654Distinct B subunits of PP2A regulate the NF-κB signalling pathway through dephosphorylation of IKKβ, IκBα and RelA.
Q46699535Ductal Carcinoma In Situ Biology, Biomarkers, and Diagnosis
Q58595841Ductal Carcinoma in Situ Biomarkers in a Precision Medicine Era: Current and Future Molecular-Based Testing
Q38696796Ductal carcinoma in situ - update on risk assessment and management
Q33656372Effects on specific promoter DNA methylation in zebrafish embryos and larvae following benzo[a]pyrene exposure
Q53262835Epigenetic progression of columnar cell lesions of the breast to invasive breast cancer
Q37865530Epigenetic regulation of drug processing genes
Q39311503Epigenetic silencing of miR-200c in breast cancer is associated with aggressiveness and is modulated by ZEB1.
Q38042440Epigenetic-dependent regulation of drug transport and metabolism: an update
Q35190483Epigenetics in breast and prostate cancer
Q49624286FOXC1 in cancer development and therapy: deciphering its emerging and divergent roles
Q34543873FOXC1 is a critical mediator of EGFR function in human basal-like breast cancer
Q39564479FOXC1, a target of polycomb, inhibits metastasis of breast cancer cells
Q39176111FOXC1: an emerging marker and therapeutic target for cancer
Q90613095Forkhead box C1 promotes metastasis and invasion of non-small cell lung cancer by binding directly to the lysyl oxidase promoter
Q28505995Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth
Q36476460FoxC1-Dependent Regulation of Vascular Endothelial Growth Factor Signaling in Corneal Avascularity
Q34196315Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis
Q36096510Heterogeneous DNA Methylation Patterns in the GSTP1 Promoter Lead to Discordant Results between Assay Technologies and Impede Its Implementation as Epigenetic Biomarkers in Breast Cancer
Q44573227Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors.
Q35871547Hormone Replacement Therapy Associated White Blood Cell DNA Methylation and Gene Expression are Associated With Within-Pair Differences of Body Adiposity and Bone Mass
Q33556583Hypermethylation of CDKN2A exon 2 in tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients
Q38848220Identification of genes associated with renal cell carcinoma using gene expression profiling analysis
Q34066320Integrating multi-omics for uncovering the architecture of cross-talking pathways in breast cancer
Q47805346Lifetime exposure to ambient air pollution and methylation of tumor suppressor genes in breast tumors
Q49680751Loss of ABCB4 attenuates the caspase-dependent apoptosis regulating resistance to 5-Fu in colorectal cancer
Q34876968MCT-1 expression and PTEN deficiency synergistically promote neoplastic multinucleation through the Src/p190B signaling activation
Q35169101Methyl-binding domain protein 2-dependent proliferation and survival of breast cancer cells.
Q33577711Methylation profile of TP53 regulatory pathway and mtDNA alterations in breast cancer patients lacking TP53 mutations
Q35000210Methylation profiling of ductal carcinoma in situ and its relationship to histopathological features
Q38503758Methylation profiling with a panel of cancer related genes: association with estrogen receptor, TP53 mutation status and expression subtypes in sporadic breast cancer
Q26775086MiRNAs and Other Epigenetic Changes as Biomarkers in Triple Negative Breast Cancer
Q93108431MicroRNA Regulation of Epigenetic Modifiers in Breast Cancer
Q36827700MicroRNA-495 downregulates FOXC1 expression to suppress cell growth and migration in endometrial cancer
Q37376285Multiplicity of acquired cross-resistance in paclitaxel-resistant cancer cells is associated with feedback control of TUBB3 via FOXO3a-mediated ABCB1 regulation
Q36796453PP2A Counterbalances Phosphorylation of pRB and Mitotic Proteins by Multiple CDKs: Potential Implications for PP2A Disruption in Cancer
Q28088747PP2A: The Wolf in Sheep's Clothing?
Q53449089Promoter CpG island hypermethylation during breast cancer progression
Q87641396Promoter hypermethylation may be an important mechanism of the transcriptional inactivation of ARRDC3, GATA5, and ELP3 in invasive ductal breast carcinoma
Q37687390Promoter methylation patterns of ABCB1, ABCC1 and ABCG2 in human cancer cell lines, multidrug-resistant cell models and tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients.
Q39023899Protein expression and methylation of MGMT, a DNA repair gene and their correlation with clinicopathological parameters in invasive ductal carcinoma of the breast.
Q49380019Protein interactomes of protein phosphatase 2A B55 regulatory subunits reveal B55-mediated regulation of replication protein A under replication stress
Q35008011Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
Q55496828Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program.
Q64245323The Diverse Consequences of Deregulation in Cancer
Q35687321The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain
Q37251018The association between phosphatase and tensin homolog hypermethylation and patients with breast cancer, a meta-analysis and literature review
Q37261822The association of PTEN hypermethylation and breast cancer: a meta-analysis
Q37772356The epigenetics of breast cancer
Q43914090The forkhead box C1 (FOXC1) transcription factor is downregulated in acute promyelocytic leukemia.
Q34088277The promoter methylation status and mRNA expression levels of CTCF and SIRT6 in sporadic breast cancer
Q47327040Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer.
Q60529799Validation of DNA promoter hypermethylation biomarkers in breast cancer — a short report
Q90710834Whole-Exome Sequencing Analysis of the Progression from Non-Low Grade Ductal Carcinoma In Situ to Invasive Ductal Carcinoma
Q36795811Wnt pathway antagonists, SFRP1, SFRP2, SOX17, and PPP2R2B, are methylated in gliomas and SFRP1 methylation predicts shorter survival.
Q47142555microRNA Expression in Ethnic Specific Early Stage Breast Cancer: an Integration and Comparative Analysis

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