MicroRNA-495 downregulates FOXC1 expression to suppress cell growth and migration in endometrial cancer

scientific article published on 22 July 2015

MicroRNA-495 downregulates FOXC1 expression to suppress cell growth and migration in endometrial cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S13277-015-3686-6
P932PMC publication ID4841847
P698PubMed publication ID26198045
P5875ResearchGate publication ID280393231

P2093author name stringJing Tian
Quan Hao
Li-Rong Yin
Yan-Ying Xu
P2860cites workFunctional interactions between FOXC1 and PITX2 underlie the sensitivity to FOXC1 gene dose in Axenfeld-Rieger syndrome and anterior segment dysgenesisQ24302555
Identification of FOXC1 as a TGF-beta1 responsive gene and its involvement in negative regulation of cell growthQ24314589
Cancer statistics, 2013Q27860762
Oncomirs - microRNAs with a role in cancerQ27860773
Human FOX gene family (Review)Q28288603
FOXC1 contributes to microvascular invasion in primary hepatocellular carcinoma via regulating epithelial-mesenchymal transitionQ28910325
The IGF Hormonal Network in Endometrial Cancer: Functions, Regulation, and Targeting ApproachesQ33658023
MiR-205 inhibits cell apoptosis by targeting phosphatase and tensin homolog deleted on chromosome ten in endometrial cancer Ishikawa cellsQ33815178
Noncoding RNAs and CancerQ57187779
Uterine serous and grade 3 endometrioid carcinomas: is there a survival difference?Q80796874
MicroRNA-30d promotes tumor invasion and metastasis by targeting Galphai2 in hepatocellular carcinomaQ82421694
Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancerQ33892868
MicroRNA-101 targets EZH2, MCL-1 and FOS to suppress proliferation, invasion and stem cell-like phenotype of aggressive endometrial cancer cellsQ34227586
FOXC1 is a critical mediator of EGFR function in human basal-like breast cancerQ34543873
Rare uterine cancersQ34563024
Down-regulation of miRNA-106b inhibits growth of melanoma cells by promoting G1-phase cell cycle arrest and reactivation of p21/WAF1/Cip1 proteinQ34786521
MicroRNA-9 promotes tumor metastasis via repressing E-cadherin in esophageal squamous cell carcinomaQ34956599
Loss of estrogen-regulated microRNA expression increases HER2 signaling and is prognostic of poor outcome in luminal breast cancerQ34979662
LOC401317, a p53-regulated long non-coding RNA, inhibits cell proliferation and induces apoptosis in the nasopharyngeal carcinoma cell line HNE2.Q35448269
miR-639 regulates transforming growth factor beta-induced epithelial-mesenchymal transition in human tongue cancer cells by targeting FOXC1.Q35713143
The forkhead box transcription factor FOXC1 promotes breast cancer invasion by inducing matrix metalloprotease 7 (MMP7) expression.Q36098052
Molecular and pathologic aspects of endometrial carcinogenesisQ36617660
Foxc1 controls the growth of the murine frontal bone rudiment by direct regulation of a Bmp response threshold of Msx2.Q36640846
Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis.Q36993572
PRL PTPs: mediators and markers of cancer progressionQ37068759
Prognostic significance of miR-194 in endometrial cancer.Q37169644
Role of miR-34a as a suppressor of L1CAM in endometrial carcinomaQ37660308
Treatment options for advanced endometrial carcinomaQ37707615
Forkhead transcription factors: key players in health and diseaseQ37867229
The PI3K/AKT/mTOR pathway as a therapeutic target in endometrial cancerQ38053414
Molecular pathology of endometrial carcinomaQ38067440
MicroRNAs in endometrial cancer.Q38079122
Molecular mechanisms of endometrial stromal sarcoma and undifferentiated endometrial sarcoma as premises for new therapeutic strategiesQ38240352
Circulating microRNA biomarker studies: pitfalls and potential solutionsQ38267750
miR-99a suppresses the metastasis of human non-small cell lung cancer cells by targeting AKT1 signaling pathwayQ38960051
Dysregulation of microRNA-204 mediates migration and invasion of endometrial cancer by regulating FOXC1.Q39576706
miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1.Q39604058
MicroRNA-130b regulates the tumour suppressor RUNX3 in gastric cancerQ39736530
MicroRNA-27a directly targets KRAS to inhibit cell proliferation in esophageal squamous cell carcinomaQ41850618
miR-495 and miR-551a inhibit the migration and invasion of human gastric cancer cells by directly interacting with PRL-3.Q45878289
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P921main subjectcell migrationQ189092
cell growthQ189159
microRNAQ310899
P304page(s)239-251
P577publication date2015-07-22
P1433published inTumor BiologyQ15757842
P1476titleMicroRNA-495 downregulates FOXC1 expression to suppress cell growth and migration in endometrial cancer
P478volume37

Reverse relations

cites work (P2860)
Q64228195Bioinformatic analysis of miR-4792 regulates flavone to inhibit proliferation, invasion, and induce apoptosis of A549 cells
Q49624286FOXC1 in cancer development and therapy: deciphering its emerging and divergent roles
Q37733027FOXC1 promotes proliferation and epithelial-mesenchymal transition in cervical carcinoma through the PI3K-AKT signal pathway
Q93090297FOXC1 silencing inhibits the epithelial‑to‑mesenchymal transition of glioma cells: Involvement of β‑catenin signaling
Q90090965FOXC1 up-regulates the expression of toll-like receptors in myocardial ischaemia
Q52682253FOXC1, the new player in the cancer sandbox.
Q39176111FOXC1: an emerging marker and therapeutic target for cancer
Q41623598Forkhead box C1 is targeted by microRNA-133b and promotes cell proliferation and migration in osteosarcoma
Q42339290Knockdown of long non-coding RNA XIST increases blood-tumor barrier permeability and inhibits glioma angiogenesis by targeting miR-137.
Q46332987MiR-143 inhibits endometrial cancer cell proliferation and metastasis by targeting MAPK1.
Q41477279MiRNA-target network analysis identifies potential biomarkers for Traditional Chinese Medicine (TCM) syndrome development evaluation in hepatitis B caused liver cirrhosis
Q58700608MicroRNA-495 Confers Increased Sensitivity to Chemotherapeutic Agents in Gastric Cancer via the Mammalian Target of Rapamycin (mTOR) Signaling Pathway by Interacting with Human Epidermal Growth Factor Receptor 2 (ERBB2)
Q38718003MicroRNA-495 Inhibits Gastric Cancer Cell Migration and Invasion Possibly via Targeting High Mobility Group AT-Hook 2 (HMGA2).
Q42269566MicroRNA-495 Inhibits New Bone Regeneration via Targeting High Mobility Group AT-Hook 2 (HMGA2).
Q38782227MicroRNA-495 Regulates Migration and Invasion in Prostate Cancer Cells Via Targeting Akt and mTOR Signaling
Q52609351MicroRNA-495 inhibits proliferation, metastasis and promotes apoptosis by targeting Twist1 in gastric cancer cells.
Q49449309MicroRNA-495 suppresses cell proliferation and invasion of hepatocellular carcinoma by directly targeting insulin-like growth factor receptor-1.
Q39333266MicroRNAs in gynecological cancers: Small molecules with big implications
Q38700201Overexpression of microRNA-194 suppresses the epithelial-mesenchymal transition in targeting stem cell transcription factor Sox3 in endometrial carcinoma stem cells
Q37628264Targeting MicroRNAs in Cancer Gene Therapy
Q64245323The Diverse Consequences of Deregulation in Cancer
Q38820391The future therapy of endometrial cancer: microRNA's functionality, capability, and putative clinical application.
Q55365074miR-495 inhibits proliferation, migration, and invasion and induces apoptosis via inhibiting PBX3 in melanoma cells.
Q41520257miR-495 sensitizes MDR cancer cells to the combination of doxorubicin and taxol by inhibiting MDR1 expression
Q98562940microRNA-495 alleviates endothelial cell inflammatory injury in coronary heart disease via blockade of the NF-κB pathway by targeting RALB

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