MicroRNA-495 Confers Increased Sensitivity to Chemotherapeutic Agents in Gastric Cancer via the Mammalian Target of Rapamycin (mTOR) Signaling Pathway by Interacting with Human Epidermal Growth Factor Receptor 2 (ERBB2)

MicroRNA-495 Confers Increased Sensitivity to Chemotherapeutic Agents in Gastric Cancer via the Mammalian Target of Rapamycin (mTOR) Signaling Pathway by Interacting with Human Epidermal Growth Factor Receptor 2 (ERBB2) is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.12659/MSM.909458
P932PMC publication ID6122272
P698PubMed publication ID30147110

P2093author name stringNa Li
Yong Tang
Mei Han
Ning Zhou
Xu-Shan Tang
P2860cites workTargeted inhibition of mammalian target of rapamycin (mTOR) signaling pathway inhibits proliferation and induces apoptosis of laryngeal carcinoma cells in vitroQ50253712
Human epidermal growth factor receptor-2 expression in primary and metastatic gastric cancer.Q51006230
MicroRNA-495 regulates the proliferation and apoptosis of human umbilical vein endothelial cells by targeting chemokine CCL2Q51118725
Using circular RNA as a novel type of biomarker in the screening of gastric cancer.Q53605746
[New guidelines to evaluate the response to treatment "RECIST"]Q73355244
Expression of retinoblastoma and cyclin D1 in gastric carcinomaQ83201337
HIF2α is associated with poor prognosis and affects the expression levels of survivin and cyclin D1 in gastric carcinomaQ85843714
Nested case-control study of selected systemic autoimmune diseases in World Trade Center rescue/recovery workersQ23917420
DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancerQ27851634
p130Cas promotes invasiveness of three-dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR/p70S6K and Rac1Q28296191
Role of chemotherapy for advanced/recurrent gastric cancer: an individual-patient-data meta-analysisQ30586297
Inhibition of the mammalian target of rapamycin (mTOR) by rapamycin increases chemosensitivity of CaSki cells to paclitaxelQ33236663
Overcoming chemotherapy drug resistance by targeting inhibitors of apoptosis proteins (IAPs)Q33841579
Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancerQ33882085
Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysisQ34089030
The mTOR pathway affects proliferation and chemosensitivity of urothelial carcinoma cells and is upregulated in a subset of human bladder cancersQ35050634
Downregulation of human epidermal growth factor receptor 2 by short hairpin RNA increases chemosensitivity of human ovarian cancer cellsQ35742199
Downregulation of microRNA‑33a promotes cyclin‑dependent kinase 6, cyclin D1 and PIM1 expression and gastric cancer cell proliferationQ36224976
Phosphorylated Mammalian Target of Rapamycin p-mTOR Is a Favorable Prognostic Factor than mTOR in Gastric CancerQ36231547
Study of regulatory promoter polymorphism (-248 G>A) of Bax gene in patients with gastric cancer in the northern provinces of IranQ36432221
MicroRNA-495 downregulates FOXC1 expression to suppress cell growth and migration in endometrial cancerQ36827700
New inhibitors of the mammalian target of rapamycin signaling pathway for cancer.Q37766888
Advanced gastric cancer (GC) and cancer of the gastro-oesophageal junction (GEJ): focus on targeted therapies.Q37831541
MicroRNA: a prognostic biomarker and a possible druggable target for circumventing multidrug resistance in cancer chemotherapyQ38172970
MicroRNA-495 Inhibits Gastric Cancer Cell Migration and Invasion Possibly via Targeting High Mobility Group AT-Hook 2 (HMGA2).Q38718003
Matrix Metalloproteinases and Their Tissue Inhibitors in Comparison to Other Inflammatory Proteins in Gastric Cancer (GC).Q38896287
Inhibition of mTOR signalling potentiates the effects of trichostatin A in human gastric cancer cell lines by promoting histone acetylationQ39096573
MicroRNA Regulation of Growth Factor Receptor Signaling in Human Cancer CellsQ39646854
Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes.Q41038524
Human epidermal growth factor receptor 2 (HER-2) status evaluation in advanced gastric cancer using immunohistochemistry versus silver in situ hybridizationQ41913750
miR-495 and miR-551a inhibit the migration and invasion of human gastric cancer cells by directly interacting with PRL-3.Q45878289
Ataxia-telangiectasia-mutated protein expression with microsatellite instability in gastric cancer as prognostic markerQ46918884
Comparison of HER2 and Lauren Classification between Biopsy and Surgical Resection Samples, Primary and Metastatic Samples of Gastric CancerQ47096927
MicroRNA-495-3p functions as a tumor suppressor by regulating multiple epigenetic modifiers in gastric carcinogenesis.Q47678061
MicroRNA-199a-3p regulates endometrial cancer cell proliferation by targeting mammalian target of rapamycin (mTOR).Q48010956
Downregulation of MicroRNA-147 Inhibits Cell Proliferation and Increases the Chemosensitivity of Gastric Cancer Cells to 5-Fluorouracil by Directly Targeting PTEN.Q48649622
P407language of work or nameEnglishQ1860
P921main subjectsirolimusQ32089
microRNAQ310899
chemotherapyQ974135
P1104number of pages13
P304page(s)5960-5972
P577publication date2018-08-27
P1433published inMedical Science MonitorQ15756323
P1476titleMicroRNA-495 Confers Increased Sensitivity to Chemotherapeutic Agents in Gastric Cancer via the Mammalian Target of Rapamycin (mTOR) Signaling Pathway by Interacting with Human Epidermal Growth Factor Receptor 2 (ERBB2)
P478volume24

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cites work (P2860)
Q64251035Genetic Analyses Confirm SNPs in HSPA8 and ERBB2 are Associated with Milk Protein Concentration in Chinese Holstein Cattle
Q96300671MiR-486-5p enhances cisplatin sensitivity of human muscle-invasive bladder cancer cells by induction of apoptosis and down-regulation of metastatic genes
Q92533658Research Progress in microRNA-Based Therapy for Gastric Cancer
Q91972782miR-876-5p suppresses breast cancer progression through targeting TFAP2A

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