Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes.

scientific article published on 20 April 2015

Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NM.3850
P698PubMed publication ID25894828

P50authorYong Gang YueQ87154542
Kyoung-Mee KimQ88377030
P2093author name stringJian Wang
Kun Yu
Patrick Tan
Ronghua Chen
Christoph Reinhard
Andrey Loboda
Mark Ayers
Michael Nebozhyn
Sin-Ho Jung
Insuk Sohn
Se Hoon Park
Jason C Ting
Sung Kim
Jason Gang Jin
Jeeyun Lee
Seung Tae Kim
Won Ki Kang
Joon Ho Lee
In-Gu Do
Jiangang Liu
Razvan Cristescu
Jae Moon Bae
Min Gew Choi
Tae Sung Sohn
Xiang S Ye
Amit Aggarwal
Shawn Liu
James Hardwick
Swee Seong Wong
Jake Fu
Dai Hongyue
Lara Gong
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P433issue5
P407language of work or nameEnglishQ1860
P304page(s)449-456
P577publication date2015-04-20
P1433published inNature MedicineQ1633234
P1476titleMolecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes
P478volume21

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Q90198316Molecular subtyping of gastric cancer with respect to the growth pattern of lymph-node metastases
Q38772049Monoclonal antibodies for treating gastric cancer: promises and pitfalls
Q37664258Mouse models for gastric cancer: Matching models to biological questions.
Q41213684Moving molecular subtypes to the clinic in gastric cancer
Q92571327Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response
Q57462245Mutational Analysis Identifies Therapeutic Biomarkers in Inflammatory Bowel Disease-Associated Colorectal Cancers
Q60916561Mutations Defining Patient Cohorts With Elevated PD-L1 Expression in Gastric Cancer
Q64112592NPTX1 promotes metastasis via integrin/FAK signaling in gastric cancer
Q55077233NanoString expression profiling identifies candidate biomarkers of RAD001 response in metastatic gastric cancer.
Q91942835Neoantigens Derived from Recurrently Mutated Genes as Potential Immunotherapy Targets for Gastric Cancer
Q92512158Neutralizing antibody to FGFR2 can act as a selective biomarker and potential therapeutic agent for gastric cancer with FGFR2 amplification
Q42090072New Biology to New Treatment of Helicobacter pylori-Induced Gastric Cancer
Q38759129New agents on the horizon in gastric cancer
Q59136693New drug developments in metastatic gastric cancer
Q55527185New therapeutic options opened by the molecular classification of gastric cancer.
Q64990976Next-generation sequencing and biomarkers for gastric cancer: what is the future?
Q47323830Nomogram-based prediction of survival in patients with advanced oesophagogastric adenocarcinoma receiving first-line chemotherapy: a multicenter prospective study in the era of trastuzumab.
Q26785700Noncoding Genomics in Gastric Cancer and the Gastric Precancerous Cascade: Pathogenesis and Biomarkers
Q52599496Novel Systemic Therapies for Advanced Gastric Cancer.
Q38556435Novel biomarkers for the identification and targeted therapy of gastric cancer
Q26765208Novel targets in the treatment of advanced gastric cancer: a perspective review
Q97520401Observational cohort study of clinical outcome in Epstein-Barr virus associated gastric cancer patients
Q38816897Oesophageal adenocarcinoma and gastric cancer: should we mind the gap?
Q64934996Orthotopic Patient-Derived Xenografts of Gastric Cancer to Decipher Drugs Effects on Cancer Stem Cells and Metastatic Dissemination.
Q52720624Outlooks on Epstein-Barr virus associated gastric cancer.
Q64983568PD-L1 and immune infiltrates are differentially expressed in distinct subgroups of gastric cancer.
Q47157362PIK3CA mutations are associated with increased tumor aggressiveness and Akt activation in gastric cancer
Q91729236PTPRD-inactivation-induced CXCL8 promotes angiogenesis and metastasis in gastric cancer and is inhibited by metformin
Q39104058Pathogenesis of Gastric Cancer: Genetics and Molecular Classification.
Q54982215Pathway- and clinical-factor-based risk model predicts the prognosis of patients with gastric cancer.
Q36413247Patient-derived cell models as preclinical tools for genome-directed targeted therapy
Q47167566Patient-derived xenograft in zebrafish embryos: a new platform for translational research in gastric cancer
Q94564081Perineural Invasion and Postoperative Adjuvant Chemotherapy Efficacy in Patients With Gastric Cancer
Q64064533Perioperative Treatment in Resectable Gastric Cancer: Current Perspectives and Future Directions
Q38842137Personalised Treatment in Gastric Cancer: Myth or Reality?
Q54052500Personalised therapy for localised gastric and gastro-oesophageal adenocarcinoma.
Q59330022Personalized risk assessment for dynamic transition of gastric neoplasms
Q44288144Phase I dose-escalation study of the c-Met tyrosine kinase inhibitor SAR125844 in Asian patients with advanced solid tumors, including patients with MET-amplified gastric cancer
Q91788788Phosphoglucose isomerase gene expression as a prognostic biomarker of gastric cancer
Q89495545Pizotifen inhibits the proliferation and invasion of gastric cancer cells
Q61811918Polymorphisms in RAS/RAF/MEK/ERK Pathway Are Associated with Gastric Cancer
Q36234652Poorly Differentiated Medullary Phenotype Predicts Poor Survival in Early Lymph Node-Negative Gastro-Esophageal Adenocarcinomas
Q90064455Positive Status of Epstein-Barr Virus as a Biomarker for Gastric Cancer Immunotherapy: A Prospective Observational Study
Q38824375Potentially Curable Cancers of the Esophagus and Stomach.
Q94465339Precision Medicine in Non Communicable Diseases
Q99708836Precision Medicine to Treat Advanced Gastroesophageal Adenocarcinoma: A Work in Progress
Q88136015Precision medicine in the adjuvant treatment of gastric cancer
Q88136013Predictive test for chemotherapy response in resectable gastric cancer: a multi-cohort, retrospective analysis
Q42378389Profiling cancer-associated genetic alterations and molecular classification of cancer in Korean gastric cancer patients.
Q37342600Prognostic Importance of Cell Cycle Regulators Cyclin D1 (CCND1) and Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B/p27) in Sporadic Gastric Cancers.
Q88177642Prognostic Value of Perineural Invasion in Resected Gastric Cancer Patients According to Lauren Histotype
Q90257564Prognostic and Predictive Value of Microsatellite Instability, Inflammatory Reaction and PD-L1 in Gastric Cancer Patients Treated with Either Adjuvant 5-FU/LV or Sequential FOLFIRI Followed by Cisplatin and Docetaxel: A Translational Analysis from t
Q92801850Prognostic implication of molecular subtypes and response to neoadjuvant chemotherapy in 760 gastric carcinomas: role of Epstein-Barr virus infection and high- and low-microsatellite instability
Q57167306Prognostic significance of tumor immune microenvironment and immunotherapy: Novel insights and future perspectives in gastric cancer
Q37706604Programmed cell death-ligand 1 expression predicts survival in patients with gastric carcinoma with microsatellite instability
Q47143363Programmed death ligand-1 and MET co-expression is a poor prognostic factor in gastric cancers after resection
Q64052649Progress and challenges in HER2-positive gastroesophageal adenocarcinoma
Q55603677Proposed Molecular and miRNA Classification of Gastric Cancer.
Q92132547RRAD expression in gastric and colorectal cancer with peritoneal carcinomatosis
Q101051347RUNX3 methylation drives hypoxia-induced cell proliferation and antiapoptosis in early tumorigenesis
Q53686273Rates of TP53 Mutation are Significantly Elevated in African American Patients with Gastric Cancer.
Q38940560Recapitulating Human Gastric Cancer Pathogenesis: Experimental Models of Gastric Cancer
Q64064673Recent advances in gastric cancer early diagnosis
Q64912862Recent advances in the management of gastric adenocarcinoma patients.
Q37687784Receptor tyrosine kinase amplified gastric cancer: Clinicopathologic characteristics and proposed screening algorithm
Q47110810Recurrence-associated gene signature optimizes recurrence-free survival prediction of colorectal cancer
Q48569564Regional differences in advanced gastric cancer: exploratory analyses of the AVAGAST placebo arm.
Q33657952Regorafenib inhibited gastric cancer cells growth and invasion via CXCR4 activated Wnt pathway
Q90814281Regulation of aberrantly expressed SERPINH1 by antitumor miR-148a-5p inhibits cancer cell aggressiveness in gastric cancer
Q91622783Reproduction of molecular subtypes of gastric adenocarcinoma by transcriptome sequencing of archival tissue
Q92259805Resolution of Gastric Cancer-Promoting Inflammation: A Novel Strategy for Anti-cancer Therapy
Q92862205Risk factors predisposing to cardia gastric adenocarcinoma: Insights and new perspectives
Q91688483Role of Cancer-Associated Fibroblast in Gastric Cancer Progression and Resistance to Treatments
Q59340320SEPROGADIC - serum protein-based gastric cancer prediction model for prognosis and selection of proper adjuvant therapy
Q37688513SPARC expression in gastric cancer predicts poor prognosis: Results from a clinical cohort, pooled analysis and GSEA assay
Q47915753Selecting patients for gastrectomy in metastatic esophago-gastric cancer: clinics and pathology are not enough.
Q36400378Seom guidelines for the treatment of gastric cancer 2015.
Q57176429Significance of Preoperative Systemic Immune Score for Stage I Gastric Cancer Patients
Q92382425Significant function and research progress of biomarkers in gastric cancer
Q50107191Silencing of peroxiredoxin II by promoter methylation is necessary for the survival and migration of gastric cancer cells
Q90437168Simultaneous inhibition of CXCR1/2, TGF-β, and PD-L1 remodels the tumor and its microenvironment to drive antitumor immunity
Q90636313Simvastatin Inhibits the Malignant Behaviors of Gastric Cancer Cells by Simultaneously Suppressing YAP and β-Catenin Signaling
Q38871189Single Center Experience on Anatomy-and Histopathology-Based Gastric Cancer Molecular Classification
Q61447416Single Patient Classifier Assay, Microsatellite Instability, and Epstein-Barr Virus Status Predict Clinical Outcomes in Stage II/III Gastric Cancer: Results from CLASSIC Trial
Q89721950Single-Cell Genomic Characterization Reveals the Cellular Reprogramming of the Gastric Tumor Microenvironment
Q91612580Somatic mutational profiles of stage II and III gastric cancer according to tumor microenvironment immune type
Q38776229Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers.
Q40192048Stratification of Digestive Cancers with Different Pathological Features and Survival Outcomes by MicroRNA Expression.
Q89535788Study on the mechanisms of compound Kushen injection for the treatment of gastric cancer based on network pharmacology
Q37362819Synergistic combination of DT-13 and topotecan inhibits human gastric cancer via myosin IIA-induced endocytosis of EGF receptor in vitro and in vivo
Q92073945Systematic Evaluation of Gastric Tumor Cell Index and Two-Drug Combination Therapy via 3-Dimensional High-Throughput Drug Screening
Q97535476Systemic chemotherapy for gastro-oesophagogastric junction adenocarcinoma and stomach adenocarcinoma in a metastatic setting
Q55472607TIMP2 is a Poor Prognostic Factor and Predicts Metastatic Biological Behavior in Gastric Cancer.
Q91982116TRPV2 Calcium Channel Gene Expression and Outcomes in Gastric Cancer Patients: A Clinically Relevant Association
Q61818369TULP3: A potential biomarker in colorectal cancer?
Q38939088Targeted therapies for advanced and metastatic adenocarcinoma of the gastroesophageal junction: is there something new?
Q41340207Targeted therapies for gastric cancer: failures and hopes from clinical trials
Q92349505Targeting the Interplay between Epithelial-to-Mesenchymal-Transition and the Immune System for Effective Immunotherapy
Q93048955Targeting the Oncogenic FGF-FGFR Axis in Gastric Carcinogenesis
Q38741697Targeting the fibroblast growth factor receptor 2 in gastric cancer: promise or pitfall?
Q64230121Ten Thousand Consecutive Gastrectomies for Gastric Cancer: Perspectives of a Master Surgeon
Q38689450The 30-year experience-A meta-analysis of randomised and high-quality non-randomised studies of hyperthermic intraperitoneal chemotherapy in the treatment of gastric cancer.
Q98771218The Better Survival of MSI Subtype Is Associated With the Oxidative Stress Related Pathways in Gastric Cancer
Q90672474The Impact of Long-term Exposure to Low Levels of Inorganic Arsenic on the Hypomethylation of SEPT9 Promoter in Epithelial-Mesenchymal Transformed Colorectal Cancer Cell Lines
Q33600436The Origins of Gastric Cancer From Gastric Stem Cells: Lessons From Mouse Models.
Q55618345The Pattern of Signatures in Gastric Cancer Prognosis.
Q57120826The Predictive Value of Epstein-Barr Virus-Positivity in Patients Undergoing Gastrectomy Followed by Adjuvant Chemotherapy
Q38710597The Profile of Serum microRNAs Predicts Prognosis for Resected Gastric Cancer Patients Receiving Platinum-Based Chemotherapy.
Q58762545The Thomsen-Friedenreich Antigen: A Highly Sensitive and Specific Predictor of Microsatellite Instability in Gastric Cancer
Q56890968The Transcriptomic Landscape of Gastric Cancer: Insights into Epstein-Barr Virus Infected and Microsatellite Unstable Tumors
Q37392801The anti-apoptotic and prognostic value of fibroblast growth factor 9 in gastric cancer
Q100428137The changing face of gastric cancer: epidemiologic trends and advances in novel therapies
Q89953553The era of laparoscopic surgery for gastric cancer: what is the present territory and what will be next?
Q28078788The genomics and therapeutics of HER2-positive gastric cancer-from trastuzumab and beyond
Q50105819The prognosis role of AJCC/UICC 8th edition staging system in gastric cancer, a retrospective analysis
Q46266500The role of intestinal bacteria in the development and progression of gastrointestinal tract neoplasms.
Q90087481The role of pembrolizumab in the treatment of PD-L1 expressing gastric and gastroesophageal junction adenocarcinoma
Q33876785The significance of a nineteenth century definition in the era of genomics: linitis plastica.
Q53108021The tumor-stromal ratio as a strong prognosticator for advanced gastric cancer patients: proposal of a new TSNM staging system.
Q91689801Three Biomarkers Predict Gastric Cancer Patients' Susceptibility To Fluorouracil-based Chemotherapy
Q58695226Towards precision medicine: linking genetic and cellular heterogeneity in gastric cancer
Q89967074Traditional Classification and Novel Subtyping Systems for Bladder Cancer
Q57211498Transcriptional analysis of immune genes in Epstein-Barr virus-associated gastric cancer and association with clinical outcomes
Q59129137Transcriptomic analysis of hepatocellular carcinoma reveals molecular features of disease progression and tumor immune biology
Q91730183Transcriptomic profiling reveals three molecular phenotypes of adenocarcinoma at the gastroesophageal junction
Q26767920Translating gastric cancer genomics into targeted therapies
Q30239109Translating genomic profiling to gastrointestinal cancer treatment
Q33829437Tumor and serum gamma-glutamyl transpeptidase, new prognostic and molecular interpretation of an old biomarker in gastric cancer.
Q47728785Tumor-associated macrophage infiltration is highly associated with PD-L1 expression in gastric adenocarcinoma.
Q89295006Tumor-infiltrating γδT cells predict prognosis and adjuvant chemotherapeutic benefit in patients with gastric cancer
Q104073775Tumor-promoting macrophages prevail in malignant ascites of advanced gastric cancer
Q92725623Upregulation of BCAM and its sense lncRNA BAN are associated with gastric cancer metastasis and poor prognosis
Q98289253Upregulation of COL8A1 indicates poor prognosis across human cancer types and promotes the proliferation of gastric cancer cells
Q37662125Validation of the Memorial Sloan Kettering Cancer Center nomogram to predict disease-specific survival in a Chinese gastric cancer population receiving postoperative chemoradiotherapy after an R0 resection
Q48218531Value of a molecular screening program to support clinical trial enrollment in Asian cancer patients: The Integrated Molecular Analysis of Cancer (IMAC) Study.
Q57159608What's New in Gastric Cancer: The Therapeutic Implications of Molecular Classifications and Future Perspectives
Q64071483Whole-genome sequencing reveals novel tandem-duplication hotspots and a prognostic mutational signature in gastric cancer
Q38751688Winding back Wnt signalling: potential therapeutic targets for treating gastric cancers
Q53750080[Novel pharmaceutical treatment approaches for gastric cancer].
Q38703593miR-551b regulates epithelial-mesenchymal transition and metastasis of gastric cancer by inhibiting ERBB4 expression
Q90598986piRNAs in Gastric Cancer: A New Approach Towards Translational Research

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