Significant function and research progress of biomarkers in gastric cancer

scientific article published on 11 November 2019

Significant function and research progress of biomarkers in gastric cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3892/OL.2019.11078
P932PMC publication ID6924079
P698PubMed publication ID31897111

P2093author name stringYong Liu
Wei Ma
Zhiwei Zhang
Yuxuan Li
Yiyang Xiao
Gaosheng Xu
Dong Mei Ye
Weiru Luo
P2860cites workWhat are biomarkers?Q24613362
Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapyQ24635408
Helicobacter pylori update: gastric cancer, reliable therapy, and possible benefitsQ27333657
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trialQ27851578
Durable complete response of metastatic gastric cancer with anti-Met therapy followed by resistance at recurrenceQ27851725
The blockade of immune checkpoints in cancer immunotherapyQ27860852
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012Q27861047
PD-1 and its ligands in tolerance and immunityQ28131650
Comprehensive molecular characterization of gastric adenocarcinomaQ28244985
HER2 testing in gastric cancer: a practical approachQ28256814
The BCL-2 protein family: opposing activities that mediate cell deathQ29547380
Landscape of transcription in human cellsQ29547467
Modular regulatory principles of large non-coding RNAsQ29617829
Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAsQ29618428
The two histological main types of gastric carcinoma: diffuse and so called intestinal-type carcinoma: an attempt at a histo-clinical classificationQ29618627
Circular RNAs are a large class of animal RNAs with regulatory potencyQ29620042
Bevacizumab in combination with chemotherapy as first-line therapy in advanced gastric cancer: a randomized, double-blind, placebo-controlled phase III studyQ29620647
Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escapeQ29620881
Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriersQ30652890
Phase II trial of everolimus in patients with refractory metastatic adenocarcinoma of the esophagus, gastroesophageal junction and stomach: possible role for predictive biomarkersQ33422778
International Programme on Chemical Safety (IPCS) environmental health criteria on boron human health risk assessmentQ33537383
Entire-volume serial histological examination for detection of micrometastases in lymph nodes of colorectal cancersQ33980405
Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysisQ34089030
Low level of p27(Kip1) protein expression in gastric adenocarcinoma is associated with disease progression and poor outcome.Q34160896
Circular RNAs: splicing's enigma variationsQ34331123
Multicenter phase II study of apatinib in non-triple-negative metastatic breast cancerQ34544166
Amplification of HER-2 in gastric carcinoma: association with Topoisomerase IIalpha gene amplification, intestinal type, poor prognosis and sensitivity to trastuzumab.Q34554455
Oral attenuated Salmonella typhimurium vaccine against MG7-Ag mimotope of gastric cancerQ35011130
Determinants of Epstein-Barr virus-positive gastric cancer: an international pooled analysis.Q35108424
Upregulation of PD-L1 and APE1 is associated with tumorigenesis and poor prognosis of gastric cancerQ35113261
Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapyQ35154288
Identification of the long non-coding RNA H19 in plasma as a novel biomarker for diagnosis of gastric cancerQ35764908
MicroRNA-335 acts as a metastasis suppressor in gastric cancer by targeting Bcl-w and specificity protein 1Q35853031
Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunityQ35870655
Intrinsic tumour suppressionQ35953133
Changes in DNA methylation are associated with the development of drug resistance in cervical cancer cellsQ36157132
A multi-center phase II study and biomarker analysis of combined cetuximab and modified FOLFIRI as second-line treatment in patients with metastatic gastric cancerQ36306554
Expression of E-cadherin and beta-catenin in gastric carcinoma and its correlation with the clinicopathological features and patient survivalQ36308479
Global DNA hypomethylation is an early event in Helicobacter pylori-related gastric carcinogenesisQ84205139
[The latest 2010 WHO classification of tumors of digestive system]Q84560118
Prognostic impact of CD133 expression in gastric carcinomaQ84586885
Expression of apoptosis-related proteins and its clinical implication in surgically resected gastric carcinomaQ84987698
Prognostic impact of circulating miR-21 in the plasma of patients with gastric carcinomaQ85785866
Correlation between infiltration of FOXP3+ regulatory T cells and expression of B7-H1 in the tumor tissues of gastric cancerQ87494688
Expression of costimulatory molecules B7-H1, B7-H4 and Foxp3+ Tregs in gastric cancer and its clinical significanceQ87827796
Recurrence of Pancreatic Neuroendocrine Tumors and Survival Predicted by Ki67Q88779898
Erratum to: Past and current trends in endoscopic diagnosis for early stage gastric cancer in JapanQ89471281
Injectable hydrogels for the sustained delivery of a HER2-targeted antibody for preventing local relapse of HER2+ breast cancer after breast-conserving surgeryQ90169792
FDA Approval Summary: Pembrolizumab for Recurrent Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing PD-L1Q91011455
Immune-checkpoint inhibitors in head and neck squamous cell carcinoma: cost-efficacy in second-line treatment based on programmed death-ligand 1 (PD-L1) levelQ92733382
Value of Combined Detection of Serum CEA, CA72-4, CA19-9 and TSGF in the Diagnosis of Gastric CancerQ95385234
Increased expression of long intergenic non-coding RNA LINC00152 in gastric cancer and its clinical significanceQ39024400
Circulating CUDR, LSINCT-5 and PTENP1 long noncoding RNAs in sera distinguish patients with gastric cancer from healthy controlsQ39037474
Anti-claudin 18.2 antibody as new targeted therapy for advanced gastric cancerQ39299196
Up-regulated long non-coding RNA H19 contributes to proliferation of gastric cancer cellsQ39317613
Long noncoding RNAs: lincs between human health and diseaseQ39376908
Alteration of DNA Methylation in Gastric Cancer with ChemotherapyQ39377814
MicroRNA-148a suppresses tumor cell invasion and metastasis by downregulating ROCK1 in gastric cancerQ39458980
Lapatinib, a dual EGFR and HER2 kinase inhibitor, selectively inhibits HER2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo.Q39736030
EGFR in gastric carcinomas: prognostic significance of protein overexpression and high gene copy numberQ40105232
PD-L1 expression analysis in gastric carcinoma tissue and blocking of tumor-associated PD-L1 signaling by two functional monoclonal antibodiesQ40185070
Gastric Cancer as Preventable DiseaseQ40203177
Gastric cancer screening using the serum pepsinogen test methodQ40250560
A Serological Biopsy Using Five Stomach-Specific Circulating Biomarkers for Gastric Cancer Risk Assessment: A Multi-Phase StudyQ40282956
Spreading of methylation within RUNX3 CpG island in gastric cancerQ40338066
Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOQ40487371
Programmed Death-Ligand 1 Expression Is Common in Gastric Cancer Associated With Epstein-Barr Virus or Microsatellite InstabilityQ40503160
Detection of circulating gastric carcinoma-associated antigen MG7-Ag in human sera using an established single determinant immuno-polymerase chain reaction techniqueQ40904978
Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes.Q41038524
Phase I Study of Pembrolizumab (MK-3475; Anti-PD-1 Monoclonal Antibody) in Patients with Advanced Solid Tumors.Q41228724
MiR-219-5p Inhibits the Growth and Metastasis of Malignant Melanoma by Targeting BCL-2.Q41528572
Current status of lymph node micrometastasis in gastric cancerQ41613126
Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor roleQ41674960
Serum pepsinogens as a screening test of extensive chronic gastritis.Q42523163
Helicobacter pylori and CagA status, serum gastrin, interleukin-8 and gastric acid secretion in gastric cancerQ42525913
Disparities in gastric cancer chemotherapy between the East and WestQ36472210
Potential diagnostic and prognostic values of detecting promoter hypermethylation in the serum of patients with gastric cancer.Q36616006
Panitumumab added to docetaxel, cisplatin and fluoropyrimidine in oesophagogastric cancer: ATTAX3 phase II trial.Q36661984
Missed diagnosis of early gastric cancer or high-grade intraepithelial neoplasiaQ36759235
Epirubicin, oxaliplatin, and capecitabine with or without panitumumab for patients with previously untreated advanced oesophagogastric cancer (REAL3): a randomised, open-label phase 3 trialQ36892840
MiR-214 regulate gastric cancer cell proliferation, migration and invasion by targeting PTEN.Q37028111
HER2 in gastric cancer: a new prognostic factor and a novel therapeutic targetQ37149210
Abundant PD-L1 expression in Epstein-Barr Virus-infected gastric cancersQ37362803
Thrombosis associated with angiogenesis inhibitors.Q37414595
Expression of CD133 in the cytoplasm is associated with cancer progression and poor prognosis in gastric cancerQ37468314
Interventions to reduce colonisation and transmission of antimicrobial-resistant bacteria in intensive care units: an interrupted time series study and cluster randomised trialQ37491940
Biomarkers of TGF-β signaling pathway and prognosis of pancreatic cancerQ37495918
The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: multiple myeloma, lymphoma, and acute leukemiaQ37517482
Ki67 in breast cancer: prognostic and predictive potentialQ37691691
MicroRNA dysregulation in gastric cancer: a new player enters the gameQ37783909
mTOR as a therapeutic target in patients with gastric cancerQ37928535
Molecular pathology of gastric cancer: research and practiceQ37946590
Novel targeted agents for gastric cancerQ38019657
Capecitabine and cisplatin with or without cetuximab for patients with previously untreated advanced gastric cancer (EXPAND): a randomised, open-label phase 3 trialQ38099726
Towards the goal of personalized medicine in gastric cancer--time to move beyond HER2 inhibition. Part II: Targeting gene mutations and gene amplifications and the angiogenesis pathwayQ38126246
Long noncoding RNAs: emerging stars in gene regulation, epigenetics and human disease.Q38200054
Review article: the epidemiology and prevention of gastric cancerQ38218870
Quantitative analysis of tumor-derived methylated RUNX3 sequences in the serum of gastric cancer patients.Q38352301
Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracilQ38490073
Clinical Significance of Four Molecular Subtypes of Gastric Cancer Identified by The Cancer Genome Atlas Project.Q38659483
Next-Generation CDK2/9 Inhibitors and Anaphase Catastrophe in Lung CancerQ38708974
Circular RNA 0000096 affects cell growth and migration in gastric cancerQ38721690
A global burden of gastric cancer: the major impact of China.Q38738402
The emerging landscape of circular RNA in life processes.Q38822247
Pembrolizumab for patients with PD-L1-positive advanced gastric cancer (KEYNOTE-012): a multicentre, open-label, phase 1b trialQ38829062
Five-year survival analysis of surgically resected gastric cancer cases in Japan: a retrospective analysis of more than 100,000 patients from the nationwide registry of the Japanese Gastric Cancer Association (2001-2007).Q38833332
Aberrant expression of UCA1 in gastric cancer and its clinical significanceQ38883468
Programmed Death Ligand-1 Immunohistochemistry: Friend or Foe?Q38921936
The emerging role and clinical implication of human exonic circular RNA.Q38944775
Rilotumumab plus epirubicin, cisplatin, and capecitabine as first-line therapy in advanced MET-positive gastric or gastro-oesophageal junction cancer (RILOMET-1): a randomised, double-blind, placebo-controlled, phase 3 trialQ42693879
Clinical significance of RacGAP1 expression at the invasive front of gastric cancerQ43781232
Survivin expression in tumor cell nuclei is predictive of a favorable prognosis in gastric cancer patientsQ44559861
Global burden of gastric cancer attributable to Helicobacter pyloriQ44946941
Histologic and serum risk markers for noncardia early gastric cancerQ45249201
Final analysis of a randomised trial comparing pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory advanced melanoma.Q45953253
A study on the prognostic value of cyclins D1 and E expression levels in resectable gastric cancer and on some correlations between cyclins expression, histoclinical parameters and selected protein products of cell-cycle regulatory genes.Q46791001
MET overexpression assessed by new interpretation method predicts gene amplification and poor survival in advanced gastric carcinomasQ46799794
Expression of pRb, Ki67 and HER 2/neu in gastric carcinomas: Relation to different histopathological grades and stagesQ46894370
Aberrant methylation of p16 predicts candidates for 5-fluorouracil-based adjuvant therapy in gastric cancer patientsQ46896443
Does histology really influence gastric cancer prognosis?Q47126414
Tumor Mutational Burden and Response Rate to PD-1 Inhibition.Q47270933
Lung cancer screening, version 1.2015: featured updates to the NCCN guidelinesQ47573694
The relevance of gastric cancer biomarkers in prognosis and pre- and post- chemotherapy in clinical practiceQ47635690
A soluble protein characteristic of the nervous systemQ47721048
Nivolumab in patients with advanced gastric or gastro-oesophageal junction cancer refractory to, or intolerant of, at least two previous chemotherapy regimens (ONO-4538-12, ATTRACTION-2): a randomised, double-blind, placebo-controlled, phase 3 trialQ47745009
Re-evaluation of mucin phenotypes of gastric minute well-differentiated-type adenocarcinomas using a series of HGM, MUC5AC, MUC6, M-GGMC, MUC2 and CD10 stainsQ47757355
Pembrolizumab for treatment of advanced gastric and gastroesophageal junction adenocarcinomaQ47864236
The cadherin superfamily at the synapse: more members, more missionsQ47872691
Mechanisms of acquired resistance to first- and second-generation EGFR tyrosine kinase inhibitors.Q50146512
Circulating tumor cell (CTC) count and epithelial growth factor receptor expression on CTCs as biomarkers for cetuximab efficacy in advanced colorectal cancer.Q50774778
Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis.Q50947118
Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden.Q52586565
c-MET Overexpression in Colorectal Cancer: A Poor Prognostic Factor for Survival.Q52632856
Five-Year Follow-Up of Nivolumab in Previously Treated Advanced Non-Small-Cell Lung Cancer: Results From the CA209-003 Study.Q52640577
[Updates and interpretation on NCCN clinical practice guidelines for gastric cancer 2017 version 5].Q52680204
The KIP/CIP family members p21^{Waf1/Cip1} and p57^{Kip2} as diagnostic markers for breast cancer.Q52923628
Circular RNA profile identifies circPVT1 as a proliferative factor and prognostic marker in gastric cancer.Q52941241
Prognostic implications of immunosuppressive protein expression in tumors as well as immune cell infiltration within the tumor microenvironment in gastric cancer.Q53249720
Gastric juice microRNA-421 is a new biomarker for screening gastric cancer.Q53265398
Using circular RNA as a novel type of biomarker in the screening of gastric cancer.Q53605746
C-MET inhibitors for advanced non-small cell lung cancer.Q53698087
Safety and Efficacy of Pembrolizumab Monotherapy in Patients With Previously Treated Advanced Gastric and Gastroesophageal Junction Cancer: Phase 2 Clinical KEYNOTE-059 Trial.Q53837214
Using circular RNA hsa_circ_0000190 as a new biomarker in the diagnosis of gastric cancer.Q54130195
Everolimus for previously treated advanced gastric cancer: results of the randomized, double-blind, phase III GRANITE-1 study.Q55322223
Tumor Mutational Burden and Efficacy of Nivolumab Monotherapy and in Combination with Ipilimumab in Small-Cell Lung CancerQ56892328
Gastric cancerQ57758203
Circular RNA YAP1 inhibits the proliferation and invasion of gastric cancer cells by regulating the miR-367-5p/p27 axisQ58599825
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countriesQ60142201
The product of the human c-erbB-2 gene: a 185-kilodalton glycoprotein with tyrosine kinase activityQ70141373
Carcinoembryonic antigen in gastric juice as an aid in diagnosis of early gastric cancerQ71431907
Schistosomes, liver flukes and Helicobacter pylori. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Lyon, 7-14 June 1994Q72152032
The cooperative role of p27 with cyclin E in the prognosis of advanced gastric carcinomaQ72992712
NIH-FDA Conference: Biomarkers and Surrogate Endpoints: Advancing Clinical Research and Applications. AbstractsQ73038254
Overexpression of p53 is associated with growth pattern and prognosis in advanced gastric cancerQ73369326
Loss of p27Kip1 expression is a strong independent prognostic factor of reduced survival in N0 gastric carcinomasQ73370164
Clinical importance of preoperative carcinoembryonic antigen and carbohydrate antigen 19-9 levels in gastric cancerQ73387820
Clinical application of methylation specific-polymerase chain reaction in serum of patients with gastric cancerQ80525682
DNA methylation and cancerQ81002014
Lymphatic and blood vessel density in the follicular patterned lesions of thyroidQ81791420
P433issue1
P921main subjectbiomarkerQ864574
research progressQ122351028
P304page(s)17-29
P577publication date2019-11-11
P1433published inOncology LettersQ20640514
P1476titleSignificant function and research progress of biomarkers in gastric cancer
P478volume19

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