| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Manuel Serrano | Q42491729 |
| Alejo Efeyan | Q74118088 | ||
| P2093 | author name string | Manuel Serrano | |
| Alejo Efeyan | |||
| P433 | issue | 9 | |
| P1104 | number of pages | 5 | |
| P304 | page(s) | 1006-1010 | |
| P577 | publication date | 2007-05-28 | |
| P1433 | published in | Cell Cycle | Q1254166 |
| P1476 | title | p53: guardian of the genome and policeman of the oncogenes | |
| P478 | volume | 6 |
| Q35925499 | A DNA repair pathway-focused score for prediction of outcomes in ovarian cancer treated with platinum-based chemotherapy |
| Q28534098 | A Novel Anticancer Agent, 8-Methoxypyrimido[4',5':4,5]thieno(2,3-b) Quinoline-4(3H)-One Induces Neuro 2a Neuroblastoma Cell Death through p53-Dependent, Caspase-Dependent and -Independent Apoptotic Pathways |
| Q35002385 | A minimally invasive assay for individual assessment of the ATM/CHEK2/p53 pathway activity |
| Q28385864 | A novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumors |
| Q36016499 | A p53 axis regulates B cell receptor-triggered, innate immune system-driven B cell clonal expansion |
| Q33561621 | A planarian p53 homolog regulates proliferation and self-renewal in adult stem cell lineages |
| Q35890126 | ALDH3A1 Plays a Functional Role in Maintenance of Corneal Epithelial Homeostasis |
| Q39545413 | AP-2β enhances p53-mediated transcription of the αB-crystallin gene through stabilizing p53. |
| Q48015034 | Acetyl-11-keto-beta-boswellic acid (AKBA) prevents human colonic adenocarcinoma growth through modulation of multiple signaling pathways |
| Q27303150 | Acetylation of lysine 382 and phosphorylation of serine 392 in p53 modulate the interaction between p53 and MDC1 in vitro |
| Q39530180 | Acquisition of p53 mutations in response to the non-genotoxic p53 activator Nutlin-3. |
| Q37071040 | Alteration of WWOX in human cancer: a clinical view. |
| Q43053396 | Alterations in the p53 pathway and p16INK4a expression predict overall survival in metastatic melanoma patients treated with dacarbazine |
| Q33716323 | Alterations of tumor-related genes do not exactly match the histopathological grade in gastric adenocarcinomas |
| Q27014019 | An updated overview of HPV-associated head and neck carcinomas |
| Q42803501 | Analysis of cellular response to isocyanate using N-succinimidyl N-methylcarbamate exposure in cultured mammalian cells. |
| Q37139109 | Angiogenesis-related pathways in the pathogenesis of ovarian cancer |
| Q43543435 | Apoptosis induced by NS1 gene of Canine Parvovirus-2 is caspase dependent and p53 independent |
| Q37132824 | Apoptosis-stimulating protein of p53 (ASPP2) heterozygous mice are tumor-prone and have attenuated cellular damage-response thresholds |
| Q37703533 | Artemisinin derivative artesunate induces radiosensitivity in cervical cancer cells in vitro and in vivo |
| Q34176403 | Association of Mycoplasma hominis infection with prostate cancer |
| Q38994129 | Benzo(a)pyrene-7,8-diol-9,10-epoxide induced p53-independent necrosis via the mitochondria-associated pathway involving Bax and Bak activation |
| Q100295956 | Brca2 deficiency drives gastrointestinal tumor formation and is selectively inhibited by mitomycin C |
| Q37103465 | CCT241533 is a potent and selective inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors |
| Q37435152 | CHFR negatively regulates SIRT1 activity upon oxidative stress |
| Q64080731 | CK2-mediated CCDC106 phosphorylation is required for p53 degradation in cancer progression |
| Q30496149 | Cancer biomarker discovery: the entropic hallmark |
| Q38910879 | Carbon ion beam triggers both caspase-dependent and caspase-independent pathway of apoptosis in HeLa and status of PARP-1 controls intensity of apoptosis |
| Q37511752 | Cause and consequences of genetic and epigenetic alterations in human cancer. |
| Q34089685 | Cellular Responses to Cisplatin‐Induced DNA Damage |
| Q34041305 | Cellular senescence: from physiology to pathology |
| Q38698137 | Characterization of the new human pleomorphic undifferentiated sarcoma TP53-null cell line mfh-val2. |
| Q33370291 | Characterization of the p53 response to oncogene-induced senescence |
| Q30992438 | Classifying the Progression of Ductal Carcinoma from Single-Cell Sampled Data via Integer Linear Programming: A Case Study |
| Q37835219 | Collateral damage: insights into bacterial mechanisms that predispose host cells to cancer |
| Q36959022 | Combined effects of the p53 codon 72 and p73 G4C14-to-A4T14 polymorphisms on the risk of HPV16-associated oral cancer in never-smokers |
| Q91649552 | Comparison of responsiveness to cancer development and anti-cancer drug in three different C57BL/6N stocks |
| Q34162527 | Constant p53 pathway inactivation in a large series of soft tissue sarcomas with complex genetics |
| Q28910446 | Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway |
| Q37176269 | Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation |
| Q39515817 | DNA damage and DNA damage response in human bronchial epithelial BEAS-2B cells following exposure to 2-nitrobenzanthrone and 3-nitrobenzanthrone: role in apoptosis. |
| Q33988971 | DNA damage and DNA damage responses in THP-1 monocytes after exposure to spores of either Stachybotrys chartarum or Aspergillus versicolor or to T-2 toxin |
| Q39850003 | DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation. |
| Q34720959 | DNA replication stress, genome instability and aging |
| Q34337936 | DNA-PK, ATM and ATR collaboratively regulate p53-RPA interaction to facilitate homologous recombination DNA repair |
| Q64239237 | DRAM2 acts as an oncogene in non-small cell lung cancer and suppresses the expression of p53 |
| Q37480033 | Deficiency of pRb family proteins and p53 in invasive urothelial tumorigenesis. |
| Q38341405 | Doubles Game: Src-Stat3 versus p53-PTEN in Cellular Migration and Invasion |
| Q26784630 | Dysregulated metabolism contributes to oncogenesis |
| Q34645436 | Dysregulation of RNA polymerase I transcription during disease. |
| Q41829273 | EAPP modulates the activity of p21 and Chk2. |
| Q94468732 | Effect of linker on the binding free energy of stapled p53/HDM2 complex |
| Q92236941 | Effects of BCc1 nanoparticle and its mixture with doxorubicin on survival of murine 4T1 tumor model |
| Q30566367 | Effects of prostaglandin E2 on p53 mRNA transcription and p53 mutagenesis during T-cell-independent human B-cell clonal expansion |
| Q42381105 | Efficacy of Adoptive T-cell Therapy Is Improved by Treatment with the Antioxidant N-Acetyl Cysteine, Which Limits Activation-Induced T-cell Death |
| Q38590435 | Elevated ornithine decarboxylase levels activate ataxia telangiectasia mutated-DNA damage signaling in normal keratinocytes |
| Q64911207 | Epigenetic Control of Gene Expression in the Normal and Malignant Human Prostate: A Rapid Response Which Promotes Therapeutic Resistance. |
| Q37613538 | Evidence for ongoing DNA damage in multiple myeloma cells as revealed by constitutive phosphorylation of H2AX |
| Q36871709 | Experimental evolution reveals that high relatedness protects multicellular cooperation from cheaters |
| Q42256566 | Expression of p53 family genes in urinary bladder cancer: correlation with disease aggressiveness and recurrence. |
| Q87182618 | Flaxseed (Linum usitatissimum L.) and its total non-digestible fraction influence the expression of genes involved in azoxymethane-induced colon cancer in rats |
| Q45835625 | From rheumatic diseases to cancer - role of autoantibodies as diagnostic biomarkers |
| Q39572618 | Fused Toes Homolog modulates radiation cytotoxicity in uterine cervical cancer cells. |
| Q33654494 | Hepatic p63 regulates steatosis via IKKβ/ER stress |
| Q33329233 | High LET radiation enhances apoptosis in mutated p53 cancer cells through Caspase-9 activation |
| Q36601446 | How do K-RAS-activated cells evade cellular defense mechanisms? |
| Q35051410 | Human papillomavirus and p53 mutations in head and neck squamous cell carcinoma among Japanese population |
| Q34134333 | Human papillomavirus seropositivity synergizes with MDM2 variants to increase the risk of oral squamous cell carcinoma |
| Q47102885 | Hyperthermia exposure induces apoptosis and inhibits proliferation in HCT116 cells by upregulating miR-34a and causing transcriptional activation of p53. |
| Q28565709 | Identification and characterization of a novel Mdm2 splice variant acutely induced by the chemotherapeutic agents adriamycin and actinomycin D |
| Q37289310 | Immunohistochemistry Study of P53 and C-erbB-2 Expression in Trophoblastic Tissue and Their Predictive Values in Diagnosing Malignant Progression of Simple Molar Pregnancy |
| Q38086861 | Impact of EBV essential nuclear protein EBNA-3C on B-cell proliferation and apoptosis |
| Q28608667 | Impact of MDM2 309T>G polymorphism on sarcomagenesis |
| Q33997650 | Influence of p53 in the transition of myotrophin-induced cardiac hypertrophy to heart failure |
| Q37897197 | Interference with p53 functions in human viral infections, a target for novel antiviral strategies? |
| Q38162722 | Ionizing radiation-induced responses in human cells with differing TP53 status |
| Q28235883 | JDP2 (Jun Dimerization Protein 2)-deficient mouse embryonic fibroblasts are resistant to replicative senescence |
| Q37298409 | Jobelyn® Supplement Lowered Neuronal Degeneration: Significance of Altered p53 and ɤ-Enolase Protein Expressions in Prefrontal Cortex of Rat Exposed to Ethanol |
| Q33440643 | Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression. |
| Q30988586 | Loss of p19(Arf) facilitates the angiogenic switch and tumor initiation in a multi-stage cancer model via p53-dependent and independent mechanisms |
| Q41947077 | Lysophosphatidic Acid Inhibits Apoptosis Induced by Cisplatin in Cervical Cancer Cells |
| Q98289749 | MAGEA3 promotes proliferation and suppresses apoptosis in cervical cancer cells by inhibiting the KAP1/p53 signaling pathway |
| Q42130135 | MDM2 but not MDM4 promotes retinoblastoma cell proliferation through p53-independent regulation of MYCN translation |
| Q90571091 | MICAL2 Mediates p53 Ubiquitin Degradation through Oxidating p53 Methionine 40 and 160 and Promotes Colorectal Cancer Malignance |
| Q59326864 | MNAT1 is overexpressed in colorectal cancer and mediates p53 ubiquitin-degradation to promote colorectal cancer malignance |
| Q35563647 | Mcph1/Brit1 deficiency promotes genomic instability and tumor formation in a mouse model |
| Q89379344 | Measuring cell cycle-dependent DNA damage responses and p53 regulation on a cell-by-cell basis from image analysis |
| Q38648115 | Meta-analysis of clinical significance of p53 protein expression in patients with osteosarcoma |
| Q47850205 | Microscopy-based high-throughput assays enable multi-parametric analysis to assess adverse effects of nanomaterials in various cell lines |
| Q88178701 | Mitochondrial dysfunction suppresses p53 expression via calcium-mediated nuclear factor-kB signaling in HCT116 human colorectal carcinoma cells |
| Q33616298 | Mitochondrial matrix P53 sensitizes cells to oxidative stress |
| Q39468871 | Molecular characterization of TP53 gene in human populations exposed to low-dose ionizing radiation |
| Q37817718 | Molecular determinants of anti-EGFR sensitivity and resistance in metastatic colorectal cancer |
| Q36068317 | Molecular dynamics-based identification of novel natural mortalin-p53 abrogators as anticancer agents |
| Q39992406 | Mycoplasma infection suppresses p53, activates NF-kappaB and cooperates with oncogenic Ras in rodent fibroblast transformation |
| Q36880375 | New insights into human papillomavirus-associated head and neck squamous cell carcinoma |
| Q83474479 | New insights into oncogenic stress |
| Q36151656 | Overexpression of sPRDM16 coupled with loss of p53 induces myeloid leukemias in mice |
| Q92298314 | P53 expression in various types of hydropic placentas (through ploidy analysis as a complementary tool in diagnosis of samples) |
| Q33913135 | P53 in human melanoma fails to regulate target genes associated with apoptosis and the cell cycle and may contribute to proliferation |
| Q88640110 | Pathways of Metabolite-Related Damage to a Synthetic p53 Gene Exon 7 Oligonucleotide Using Magnetic Enzyme Bioreactor Beads and LC-MS/MS Sequencing |
| Q47228271 | Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitis. |
| Q37052183 | Photoprotection in human skin--a multifaceted SOS response |
| Q33899450 | Posttranslational modification of p53: cooperative integrators of function |
| Q28476462 | Predicting transcriptional activity of multiple site p53 mutants based on hybrid properties |
| Q39570440 | Prognostic value of the TP53 Arg72Pro single-nucleotide polymorphism and susceptibility to medulloblastoma in a cohort of Brazilian patients |
| Q28708981 | Prototypes of newly conceived inorganic and biological sensors for health and environmental applications |
| Q43089122 | RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner |
| Q42109676 | Radiation Sensitivity and Tumor Susceptibility in ATM Phospho-Mutant ATF2 Mice |
| Q34116777 | Radiation-induced cell death mechanisms |
| Q42801717 | Reconstitution of the cellular response to DNA damage in vitro using damage-activated extracts from mammalian cells |
| Q36985005 | Renal cell apoptosis induced by nephrotoxic drugs: cellular and molecular mechanisms and potential approaches to modulation |
| Q27006998 | Resistance and gain-of-resistance phenotypes in cancers harboring wild-type p53 |
| Q37447357 | Response of heterogeneous ribonuclear proteins (hnRNP) to ionising radiation and their involvement in DNA damage repair |
| Q58795265 | Resveratrol enhances cisplatin-induced apoptosis in human hepatoma cells via glutamine metabolism inhibition |
| Q33888327 | Retracted: Potential malignant transformation in the gastric mucosa of immunodeficient mice with persistent Mycoplasma penetrans infection |
| Q36311141 | Role of Gadd45a in Wip1-dependent regulation of intestinal tumorigenesis |
| Q92999956 | Role of RUNX Family Members in G1 Restriction-Point Regulation |
| Q64946390 | Role of p53 in the Regulation of the Inflammatory Tumor Microenvironment and Tumor Suppression. |
| Q34688242 | Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination |
| Q24339585 | Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma |
| Q43135527 | SOCS3 regulates p21 expression and cell cycle arrest in response to DNA damage. |
| Q54423137 | Screening for large genomic rearrangements of the BRIP1 and CHK1 genes in Finnish breast cancer families. |
| Q27028052 | Senescence in adipose-derived stem cells and its implications in nerve regeneration |
| Q37788536 | Serine/threonine phosphatases in the DNA damage response and cancer |
| Q39269601 | Significance of Wild-Type p53 Signaling in Suppressing Apoptosis in Response to Chemical Genotoxic Agents: Impact on Chemotherapy Outcome |
| Q100395262 | Single molecule studies reveal that p53 tetramers dynamically bind response elements containing one or two half sites |
| Q28585092 | SnoN functions as a tumour suppressor by inducing premature senescence |
| Q35892810 | Sodium arsenite ± hyperthermia sensitizes p53-expressing human ovarian cancer cells to cisplatin by modulating platinum-DNA damage responses |
| Q51017453 | Studies of ATM Kinase Activity Using Engineered ATM Sensitive to ATP Analogues (ATM-AS). |
| Q34055695 | Suv4-20h abrogation enhances telomere elongation during reprogramming and confers a higher tumorigenic potential to iPS cells |
| Q39436606 | Synthesis of cytochrome C oxidase 2: a p53-dependent metabolic regulator that promotes respiratory function and protects glioma and colon cancer cells from hypoxia-induced cell death |
| Q91738289 | TC2N, a novel oncogene, accelerates tumor progression by suppressing p53 signaling pathway in lung cancer |
| Q35861964 | TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells |
| Q37177918 | TP53 mutations predict disease control in metastatic colorectal cancer treated with cetuximab-based chemotherapy |
| Q36995054 | Targeting prostate cancer based on signal transduction and cell cycle pathways. |
| Q51800912 | The Role of Kinase Modulators in Cellular Senescence for Use in Cancer Treatment. |
| Q89666691 | The miR-34 family and its clinical significance in ovarian cancer |
| Q35831981 | The mitochondrial death pathway: a promising therapeutic target in diseases |
| Q28079723 | The paradox role of caspase cascade in ionizing radiation therapy |
| Q85790771 | The prognostic significance of p53 expression in gastric cancer: a meta-analysis |
| Q47106643 | The prognostic value of TP53 mutations in hypopharyngeal squamous cell carcinoma. |
| Q28072553 | The role of p53 in cancer drug resistance and targeted chemotherapy |
| Q38042630 | Therapeutic strategies for head and neck cancer based on p53 status |
| Q58041514 | Tp53 gene p72R polymorphism in chronic lymphocytic leukemia: incidence and clinical significance amongst cases with unmutated immunoglobulin receptors |
| Q36061127 | Urothelial tumor initiation requires deregulation of multiple signaling pathways: implications in target-based therapies |
| Q37820433 | What is the best frontline therapy for patients with CLL and 17p deletion? |
| Q81886345 | [Von-Hippel-Lindau (VHL) protein function by initiation and progression of renal cancer] |
| Q36044626 | p53 and mitochondrial DNA: their role in mitochondrial homeostasis and toxicity of antiretrovirals |
| Q37689054 | p53 increase mitochondrial copy number via up-regulation of mitochondrial transcription factor A in colorectal cancer |
| Q37344805 | p53 mutations associated with aging-related rise in cancer incidence rates |
| Q37247096 | p53 promotes inflammation-associated hepatocarcinogenesis by inducing HMGB1 release |
| Q37821711 | p53 regulation of podosome formation and cellular invasion in vascular smooth muscle cells |
| Q39707367 | p53-Dependent p21-mediated growth arrest pre-empts and protects HCT116 cells from PUMA-mediated apoptosis induced by EGCG. |
| Q39984297 | p53-mediated control of gene expression via mRNA translation during Endoplasmic Reticulum stress |
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