| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1007/S10555-007-9062-2 |
| P698 | PubMed publication ID | 17458507 |
| P2093 | author name string | Richard Sullivan | |
| Charles H Graham | |||
| P2860 | cites work | The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis | Q22009936 |
| P433 | issue | 2 | |
| P921 | main subject | phenotype | Q104053 |
| hypoxia | Q105688 | ||
| P304 | page(s) | 319-331 | |
| P577 | publication date | 2007-06-01 | |
| P1433 | published in | Cancer and Metastasis Reviews | Q2647982 |
| P1476 | title | Hypoxia-driven selection of the metastatic phenotype | |
| P478 | volume | 26 |
| Q60301430 | A 3D microvascular network model to study the impact of hypoxia on the extravasation potential of breast cell lines |
| Q50649161 | A Hybrid Nanomaterial for the Controlled Generation of Free Radicals and Oxidative Destruction of Hypoxic Cancer Cells. |
| Q39205750 | A microfabricated platform for establishing oxygen gradients in 3-D constructs |
| Q27330270 | A novel microfluidic platform for studying mammalian cell chemotaxis in different oxygen environments under zero-flow conditions |
| Q26864897 | A role for partial endothelial-mesenchymal transitions in angiogenesis? |
| Q90399224 | A signature of hypoxia-related factors reveals functional dysregulation and robustly predicts clinical outcomes in stage I/II colorectal cancer patients |
| Q41973667 | Angiogenic signalling pathways altered in gliomas: selection mechanisms for more aggressive neoplastic subpopulations with invasive phenotype |
| Q48135600 | Assessing chemotherapeutic effectiveness using a paper-based tumor model |
| Q48204240 | Association of des-γ-carboxy prothrombin production and Sonazoid-enhanced ultrasound findings in hepatocellular carcinomas of different histologic grades |
| Q33566900 | Ataxin-1 regulates epithelial-mesenchymal transition of cervical cancer cells |
| Q84623806 | Attenuation of reactive oxygen species by antioxidants suppresses hypoxia-induced epithelial-mesenchymal transition and metastasis of pancreatic cancer cells |
| Q37694333 | Benzimidazole analogs as potent hypoxia inducible factor inhibitors: synthesis, biological evaluation, and profiling drug-like properties |
| Q34695003 | Biomarkers for anti-angiogenic therapy in cancer. |
| Q30416514 | CD24 is an effector of HIF-1-driven primary tumor growth and metastasis |
| Q35916654 | Cancer cells that survive radiation therapy acquire HIF-1 activity and translocate towards tumour blood vessels |
| Q38272271 | Carbonic anhydrase IX: a hypoxia-controlled "catalyst" of cell migration |
| Q26778008 | Cell Death Conversion under Hypoxic Condition in Tumor Development and Therapy |
| Q38188463 | Cell adhesion molecules and their relation to (cancer) cell stemness |
| Q41541155 | Clinical and pathological staging of the cancer at the nanoscale. |
| Q35125058 | Clinical and prognostic significance of HIF-1α, PTEN, CD44v6, and survivin for gastric cancer: a meta-analysis |
| Q47616848 | Clinical and prognostic value of the C-Met/HGF signaling pathway in cervical cancer |
| Q34102029 | Comparative analysis of novel and conventional Hsp90 inhibitors on HIF activity and angiogenic potential in clear cell renal cell carcinoma: implications for clinical evaluation |
| Q35884716 | Conductive thermal ablation of 4T1 murine breast carcinoma reduces severe hypoxia in surviving tumour |
| Q53072244 | Correlation of High-Risk Soft Tissue Sarcoma Biomarker Expression Patterns with Outcome following Neoadjuvant Chemoradiation. |
| Q93052031 | Crosstalk Between Hypoxia and ER Stress Response: A Key Regulator of Macrophage Polarization |
| Q29615944 | Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics |
| Q38858648 | Design, Synthesis and Biological Evaluation of Novel HIF1α Inhibitors. |
| Q37895294 | Development of novel therapeutics targeting the urokinase plasminogen activator receptor (uPAR) and their translation toward the clinic |
| Q39636162 | Development path and current status of the NANIVID: a new device for cancer cell studies |
| Q33760006 | Differential gene expression and clonal selection during cellular transformation induced by adhesion deprivation. |
| Q24300732 | Differentiation in Neuroblastoma: Diffusion-Limited Hypoxia Induces Neuro-Endocrine Secretory Protein 55 and Other Markers of a Chromaffin Phenotype |
| Q34115628 | Distinct microRNA expression signatures are associated with melanoma subtypes and are regulated by HIF1A. |
| Q38792108 | Effects of radiation on metastasis and tumor cell migration |
| Q38176255 | Emerging roles of miR-210 and other non-coding RNAs in the hypoxic response |
| Q58093810 | Endoplasmic reticulum resident oxidase ERO1-Lalpha promotes hepatocellular carcinoma metastasis and angiogenesis through the S1PR1/STAT3/VEGF-A pathway |
| Q37744737 | Epithelial-to-mesenchymal transitions and circulating tumor cells |
| Q28253053 | Evaluation of HIF-1 inhibitors as anticancer agents |
| Q98733541 | Evidence for hypoxia increasing the tempo of evolution in glioblastoma |
| Q37252013 | Evolution of cell motility in an individual-based model of tumour growth. |
| Q27318093 | Exploring the competition between proliferative and invasive cancer phenotypes in a continuous spatial model |
| Q38802912 | Expression of Hypoxia-Associated Protein HIF-1α in Follicular Thyroid Cancer is Associated with Distant Metastasis |
| Q41682503 | Expression of N-WASP is regulated by HiF1α through the hypoxia response element in the N-WASP promoter. |
| Q39943520 | Expression of hepatocyte growth factor activator inhibitor type 1 on the epithelial cell surface is regulated by hypoxic and oxidative stresses |
| Q86657673 | Expression of hypoxia-inducible factor 1 alpha in papillary thyroid carcinoma is associated with desmoplastic stromal reaction and lymph node metastasis |
| Q54979438 | Expressional analysis of disease-relevant signalling-pathways in primary tumours and metastasis of head and neck cancers. |
| Q44670065 | Expressions of hypoxia-inducible factor-1 and epithelial cell adhesion molecule are linked with aggressive local recurrence of hepatocellular carcinoma after radiofrequency ablation therapy. |
| Q37982235 | Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities |
| Q41767159 | From tumor hypoxia to cancer progression: the implications of hypoxia-inducible factor-1 expression in cancers |
| Q31087874 | Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade |
| Q39953495 | Generation and characterization of novel local and metastatic human neuroblastoma variants |
| Q39609595 | Gensenoside Rg3 inhibits hypoxia-induced VEGF expression in human cancer cells |
| Q64273668 | Glutaminase 1 expression in colorectal cancer cells is induced by hypoxia and required for tumor growth, invasion, and metastatic colonization |
| Q37137190 | Gold Nanoparticle-Mediated Targeted Delivery of Recombinant Human Endostatin Normalizes Tumour Vasculature and Improves Cancer Therapy |
| Q51152435 | HGF/c-MET Axis in Tumor Microenvironment and Metastasis Formation. |
| Q38082457 | Head and neck cancer: from anatomy to biology |
| Q37702131 | Hemoglobin level trajectories in the early treatment period are related with survival outcomes in patients with breast cancer. |
| Q33843943 | Hepatocellular carcinomas in cirrhotic and noncirrhotic human livers share angiogenic characteristics |
| Q30579125 | Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization |
| Q37008506 | Hypoxia and cancer |
| Q37801762 | Hypoxia and hypoxia-inducible factors: master regulators of metastasis |
| Q35919809 | Hypoxia enhances cholangiocarcinoma invasion through activation of hepatocyte growth factor receptor and the extracellular signal‑regulated kinase signaling pathway |
| Q39905089 | Hypoxia generates a more invasive phenotype of tumour cells: an in vivo experimental setup based on the chorioallantoic membrane. |
| Q38400842 | Hypoxia imaging and radiotherapy: bridging the resolution gap. |
| Q55285319 | Hypoxia leads to decreased autophosphorylation of the MET receptor but promotes its resistance to tyrosine kinase inhibitors. |
| Q33908885 | Hypoxia modulates EWS-FLI1 transcriptional signature and enhances the malignant properties of Ewing's sarcoma cells in vitro |
| Q37301875 | Hypoxia promotes Rab5 activation, leading to tumor cell migration, invasion and metastasis. |
| Q35070598 | Hypoxia regulates the expression of the neuromedin B receptor through a mechanism dependent on hypoxia-inducible factor-1α |
| Q38902941 | Hypoxia upregulates Rab11-family interacting protein 4 through HIF-1α to promote the metastasis of hepatocellular carcinoma |
| Q43904364 | Hypoxia-driven cell motility reflects the interplay between JMY and HIF-1α. |
| Q95322326 | Hypoxia-induced GBE1 expression promotes tumor progression through metabolic reprogramming in lung adenocarcinoma |
| Q34671206 | Hypoxia-induced autophagic response is associated with aggressive phenotype and elevated incidence of metastasis in orthotopic immunocompetent murine models of head and neck squamous cell carcinomas (HNSCC). |
| Q37032306 | Hypoxia-induced invadopodia formation: a role for β-PIX. |
| Q39104655 | Hypoxia-induced snail expression through transcriptional regulation by HIF-1α in pancreatic cancer cells |
| Q39524246 | Hypoxia-inducible factor 1 alpha-activated angiopoietin-like protein 4 contributes to tumor metastasis via vascular cell adhesion molecule-1/integrin β1 signaling in human hepatocellular carcinoma |
| Q38108833 | Hypoxia-inducible factor-1 (HIF-1): a potential target for intervention in ocular neovascular diseases |
| Q36497267 | Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis |
| Q33665254 | Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment |
| Q24613508 | Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells |
| Q37837986 | Hypoxia-inducible factors--regulation, role and comparative aspects in tumourigenesis. |
| Q36220497 | Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy |
| Q38161730 | Hypoxia-inducible factors: mediators of cancer progression; prognostic and therapeutic targets in soft tissue sarcomas. |
| Q24651016 | Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation. |
| Q26992189 | Hypoxia-mediated regulation of macrophage functions in pathophysiology |
| Q39002822 | Hypoxia: A Double-Edged Sword in Cancer Therapy |
| Q24604279 | Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes |
| Q28535709 | IMD-0354 targets breast cancer stem cells: a novel approach for an adjuvant to chemotherapy to prevent multidrug resistance in a murine model |
| Q35665700 | Identification of a Src tyrosine kinase/SIAH2 E3 ubiquitin ligase pathway that regulates C/EBPδ expression and contributes to transformation of breast tumor cells |
| Q27007862 | Imaging tumor hypoxia to advance radiation oncology |
| Q47227510 | Impact of tumoral carbonic anhydrase IX and Ki-67 expression on survival in oral squamous cell carcinoma patients |
| Q41158583 | In Vivo Chemiluminescent Imaging Agents for Nitroreductase and Tissue Oxygenation |
| Q89626915 | Inactivation of endothelial ZEB1 impedes tumor progression and sensitizes tumors to conventional therapies |
| Q36565126 | Induction of WNT11 by hypoxia and hypoxia-inducible factor-1α regulates cell proliferation, migration and invasion |
| Q37845642 | Influence of stress on extracellular matrix and integrin biology. |
| Q46073141 | Inhibition of histone/lysine acetyltransferase activity kills CoCl2-treated and hypoxia-exposed gastric cancer cells and reduces their invasiveness |
| Q35005290 | Initial testing of the hypoxia-activated prodrug PR-104 by the pediatric preclinical testing program. |
| Q39679811 | Interleukin 6 mediated recruitment of mesenchymal stem cells to the hypoxic tumor milieu |
| Q38832528 | Investigation of hypoxia conditions using oxygen-enhanced magnetic resonance imaging measurements in glioma models |
| Q39906577 | Involvement of anoikis-resistance in the metastasis of hepatoma cells |
| Q36780880 | Involvement of decreased hypoxia-inducible factor 1 activity and resultant G1-S cell cycle transition in radioresistance of perinecrotic tumor cells. |
| Q33838696 | Isolated system towards a successful radiotherapy treatment |
| Q90010746 | Kinetics-Based Measurement of Hypoxia in Living Cells and Animals Using an Acetoxymethyl Ester Chemiluminescent Probe |
| Q33961341 | Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres. |
| Q37584073 | Light-Responsive Biodegradable Nanomedicine Overcomes Multidrug Resistance via NO-Enhanced Chemosensitization |
| Q38210491 | Linking the history of radiation biology to the hallmarks of cancer. |
| Q37392672 | Loss of AIM2 expression promotes hepatocarcinoma progression through activation of mTOR-S6K1 pathway. |
| Q37951603 | MRI of metastasis-permissive microenvironments |
| Q39845158 | Malignant progression of invasive tumour cells seen in hypoxia present an accumulation of beta-catenin in the nucleus at the tumour front. |
| Q34972161 | Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates |
| Q38393014 | Meta-analysis and gene set analysis of archived microarrays suggest implication of the spliceosome in metastatic and hypoxic phenotypes |
| Q33569072 | Meta-analysis of archived DNA microarrays identifies genes regulated by hypoxia and involved in a metastatic phenotype in cancer cells |
| Q24628401 | MiR-210--micromanager of the hypoxia pathway |
| Q38091084 | Microenvironment and radiation therapy |
| Q36432405 | Microenvironments and cellular characteristics in the micro tumor cords of malignant solid tumors |
| Q35920685 | Modulation of the tumor vasculature and oxygenation to improve therapy |
| Q36254122 | Molecular mechanisms mediating metastasis of hypoxic breast cancer cells |
| Q26851211 | Novel aspects of the liver microenvironment in hepatocellular carcinoma pathogenesis and development |
| Q52641240 | Organ-specific metastasis of breast cancer: molecular and cellular mechanisms underlying lung metastasis. |
| Q58776153 | Oxygen diffusion in ellipsoidal tumour spheroids |
| Q55074421 | Oxygen microbubbles improve radiotherapy tumor control in a rat fibrosarcoma model - A preliminary study. |
| Q37914865 | Oxygen sensing, homeostasis, and disease |
| Q90186415 | PHF19 mediated regulation of proliferation and invasiveness in prostate cancer cells |
| Q51298888 | PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis. |
| Q37347199 | PKIB promotes cell proliferation and the invasion-metastasis cascade through the PI3K/Akt pathway in NSCLC cells |
| Q89860655 | Pathological Crosstalk between Metastatic Breast Cancer Cells and the Bone Microenvironment |
| Q37785576 | Pathophysiology of oral cancer in experimental animal models: a review with focus on the role of sympathetic nerves |
| Q39509223 | Phenotype-dependent production of des-γ-carboxy prothrombin in hepatocellular carcinoma |
| Q38832371 | Phenotypic Transition as a Survival Strategy of Glioma. |
| Q37115398 | Potential of tumour cells for delivering oncolytic viruses |
| Q37883025 | Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases |
| Q37113797 | Prognostic assessment of hypoxia and metabolic markers in cervical cancer using automated digital image analysis of immunohistochemistry |
| Q53383475 | Prognostic significance of CXCL12 expression in patients with colorectal carcinoma. |
| Q34334430 | Protein kinase D1 attenuates tumorigenesis in colon cancer by modulating β-catenin/T cell factor activity |
| Q47139999 | Pulmonary function impairment predicted poor prognosis of patients with hepatocellular carcinoma after hepatectomy. |
| Q38768350 | Purinergic A2b Receptor Activation by Extracellular Cues Affects Positioning of the Centrosome and Nucleus and Causes Reduced Cell Migration. |
| Q35672610 | Radiotherapy and risks of tumor regrowth or inducing second cancer. |
| Q96639861 | Radiotherapy targeting cancer stem cells "awakens" them to induce tumour relapse and metastasis in oral cancer |
| Q35632587 | Reactive oxygen species promote ovarian cancer progression via the HIF-1α/LOX/E-cadherin pathway |
| Q64375116 | Regulation of vascularization by hypoxia-inducible factor 1 |
| Q36785948 | Relationship between human tumour angiogenic profile and combretastatin-induced vascular shutdown: an exploratory study. |
| Q46600459 | Remote-Controlled Release of Singlet Oxygen by the Plasmonic Heating of Endoperoxide-Modified Gold Nanorods: Towards a Paradigm Change in Photodynamic Therapy |
| Q39143344 | RhoA regulates invasion of glioma cells via the c-Jun NH2-terminal kinase pathway under hypoxia |
| Q26860122 | Role of hypoxia-inducible factors in breast cancer metastasis |
| Q40447356 | Simultaneous Targeting of Bladder Tumor Growth, Survival, and Epithelial-to-Mesenchymal Transition with a Novel Therapeutic Combination of Acetazolamide (AZ) and Sulforaphane (SFN). |
| Q39778331 | Solid tumours arising from differently pre-oxygenated cells: comparable growth rates despite dissimilar tissue oxygenation |
| Q34688845 | Spermidine/spermine N(1)-acetyltransferase-1 binds to hypoxia-inducible factor-1alpha (HIF-1alpha) and RACK1 and promotes ubiquitination and degradation of HIF-1alpha |
| Q37137456 | Strategies To Assess Hypoxic/HIF-1-Active Cancer Cells for the Development of Innovative Radiation Therapy |
| Q30826843 | Targeting hypoxic microenvironment of pancreatic xenografts with the hypoxia-activated prodrug TH-302. |
| Q34086671 | Targeting hypoxic tumour cells to overcome metastasis. |
| Q33667994 | Targeting of albumin-embedded paclitaxel nanoparticles to tumors |
| Q35095152 | Targeting tumor cell motility to prevent metastasis. |
| Q90449093 | The Different Routes to Metastasis via Hypoxia-Regulated Programs |
| Q40444191 | The Interaction Between Human Papillomaviruses and the Stromal Microenvironment |
| Q48308877 | The Role of Microglia in Diabetic Retinopathy: Inflammation, Microvasculature Defects and Neurodegeneration. |
| Q27025579 | The clinical importance of assessing tumor hypoxia: relationship of tumor hypoxia to prognosis and therapeutic opportunities |
| Q47318963 | The hypoxia marker CAIX is prognostic in the UK phase III VorteX-Biobank cohort: an important resource for translational research in soft tissue sarcoma. |
| Q33673803 | The lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in hypoxia: insights into cellular transformation processes mediated by HIF-1 |
| Q36997621 | The many spaces of uPAR: delivery of theranostic agents and nanobins to multiple tumor compartments through a single target |
| Q38255668 | The network of epithelial-mesenchymal transition: potential new targets for tumor resistance |
| Q37214341 | The prognostic impact of a combined carbonic anhydrase IX and Ki67 signature in oral squamous cell carcinoma |
| Q37599071 | The quinoxaline di-N-oxide DCQ blocks breast cancer metastasis in vitro and in vivo by targeting the hypoxia inducible factor-1 pathway |
| Q26775618 | The role of the oncofetal H19 lncRNA in tumor metastasis: orchestrating the EMT-MET decision |
| Q40085423 | The role of vitamin D in hepatic metastases from colorectal cancer. |
| Q38981547 | The synergistic regulation of VEGF-mediated angiogenesis through miR-190 and target genes |
| Q37187529 | The tumor microenvironment and metastatic disease |
| Q34479984 | The tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis |
| Q38805034 | Therapeutic application of anti-angiogenic nanomaterials in cancers |
| Q37111021 | Three-dimensional context regulation of metastasis |
| Q36383804 | Tissue dynamics spectroscopy for phenotypic profiling of drug effects in three-dimensional culture |
| Q58770422 | Tracing the path of cancer initiation: the AA protein-based model for cancer genesis |
| Q38807918 | Tumor cell intravasation |
| Q91525257 | Tumor diversity and the trade-off between universal cancer tasks |
| Q26995733 | Tumor endothelial cells |
| Q38155002 | Tumor hypoxia as a driving force in genetic instability. |
| Q37213623 | Tumor-microenvironment interactions: dangerous liaisons |
| Q38998166 | Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets. |
| Q37174369 | Tumour-stroma interactions in colorectal cancer: converging on beta-catenin activation and cancer stemness |
| Q50105567 | Validation of a hypoxia related gene signature in multiple soft tissue sarcoma cohorts. |
| Q38126351 | Vascular remodeling in cancer. |
| Q28395196 | miR-190 Enhances HIF-Dependent Responses to Hypoxia in Drosophila by Inhibiting the Prolyl-4-hydroxylase Fatiga |
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