Reduction in severity of a herpes simplex virus type 1 murine infection by treatment with a ribozyme targeting the UL20 gene RNA.

scientific article published on 28 May 2008

Reduction in severity of a herpes simplex virus type 1 murine infection by treatment with a ribozyme targeting the UL20 gene RNA. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.02720-07
P932PMC publication ID2493317
P698PubMed publication ID18508896

P50authorAlfred S. LewinQ42708657
Jia LiuQ79328546
P2093author name stringDavid C Bloom
Gregory S Schultz
Sonal S Tuli
Steven C Ghivizzani
P2860cites workMfold web server for nucleic acid folding and hybridization predictionQ24498105
Herpes simplex virus epidemiology and ocular importanceQ31973410
Effective inhibition of herpes simplex virus 1 gene expression and growth by engineered RNase P ribozymeQ34004603
The complete DNA sequence of varicella-zoster virusQ34162480
The catalytic diversity of RNAsQ34426633
Altering the expression kinetics of VP5 results in altered virulence and pathogenesis of herpes simplex virus type 1 in miceQ34969772
Preservation of photoreceptor morphology and function in P23H rats using an allele independent ribozyme.Q35603911
Two distinct loci confer resistance to acycloguanosine in herpes simplex virus type 1Q36365046
Ocular herpes simplex: changing epidemiology, emerging disease patterns, and the potential of vaccine prevention and therapyQ36401951
Localization and putative function of the UL20 membrane protein in cells infected with herpes simplex virus 1.Q36637226
Nucleotide sequence analysis of a 30-kb region of the bovine herpesvirus 1 genome which exhibits a colinear gene arrangement with the UL21 to UL4 genes of herpes simplex virusQ36709126
The UL20 gene of herpes simplex virus 1 encodes a function necessary for viral egressQ36827799
The herpes simplex virus type 1 latency-associated transcript (LAT) enhancer/rcr is hyperacetylated during latency independently of LAT transcriptionQ37596970
The herpes simplex virus type 1 UL20 protein modulates membrane fusion events during cytoplasmic virion morphogenesis and virus-induced cell fusionQ37730816
Construction of adenovirus vectors through Cre-lox recombinationQ39878424
The UL20 gene product of pseudorabies virus functions in virus egress.Q39880404
An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infectionQ40347915
Transcription of the Herpes Simplex Virus Genome during Productive and Latent InfectionQ40473966
A ribozyme derived from the catalytic subunit of RNase P from Escherichia coli is highly effective in inhibiting replication of herpes simplex virus 1.Q40857806
Group I and group II intronsQ40870312
Identification of a novel expressed open reading frame situated between genes U(L)20 and U(L)21 of the herpes simplex virus 1 genomeQ40905559
Investigation of herpes simplex virus type 1 genes encoding multiply inserted membrane proteinsQ41689522
The virulence-determining genomic BamHI fragment 4 of pseudorabies virus contains genes corresponding to the UL15 (partial), UL18, UL19, UL20, and UL21 genes of herpes simplex virus and a putative origin of replicationQ42600637
Identification and DNA sequence analysis of the Marek's disease virus serotype 2 genes homologous to the herpes simplex virus type 1 UL20 and UL21.Q42606656
Importance of the herpes simplex virus UL24 gene for productive ganglionic infection in mice.Q42673922
Designing and characterizing hammerhead ribozymes for use in AAV vector-mediated retinal gene therapiesQ43908574
Comparative efficacy of expression of genes delivered to mouse sensory neurons with herpes virus vectors.Q44156744
Gene transfer to articular chondrocytes with recombinant adenovirusQ44960504
Rapid determination of antiviral drug susceptibility of herpes simplex virus types 1 and 2 by real-time PCR.Q45421107
Synergistic effects on ganglionic herpes simplex virus infections by mutations or drugs that inhibit the viral polymerase and thymidine kinaseQ45784444
Design and Validation of Therapeutic Hammerhead Ribozymes for Autosomal Dominant DiseasesQ58119450
[49] Ribozymes in treatment of inherited retinal diseaseQ58119623
Latent infections induced by herpes simplex virusesQ68664117
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectribozymeQ205858
Herpes simplex virus type 1Q655331
P304page(s)7467-7474
P577publication date2008-05-28
P1433published inJournal of VirologyQ1251128
P1476titleReduction in severity of a herpes simplex virus type 1 murine infection by treatment with a ribozyme targeting the UL20 gene RNA
P478volume82

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cites work (P2860)
Q40115985Binding of Herpes Simplex Virus 1 UL20 to GODZ (DHHC3) Affects Its Palmitoylation and Is Essential for Infectivity and Proper Targeting and Localization of UL20 and Glycoprotein K.
Q40187650Bolstering the Number and Function of HSV-1-Specific CD8+ Effector Memory T Cells and Tissue-Resident Memory T Cells in Latently Infected Trigeminal Ganglia Reduces Recurrent Ocular Herpes Infection and Disease.
Q38184158DNA cleavage enzymes for treatment of persistent viral infections: recent advances and the pathway forward.
Q30459643Gene therapy in the cornea: 2005--present
Q64096639Genotypic and Phenotypic Diversity of Herpes Simplex Virus 2 within the Infected Neonatal Population
Q92376567Hepatitis E Virus Drug Development
Q59359652Knockdown of the Herpes Simplex Virus 1 Latency-Associated Transcript Reduces Reactivation from Latency
Q30499249M062 is a host range factor essential for myxoma virus pathogenesis and functions as an antagonist of host SAMD9 in human cells
Q42224370Unfolding of in planta activity of anti-rep ribozyme in presence of a RNA silencing suppressor
Q39851109pcDNA3.1(-)-mediated ribozyme targeting of HER-2 suppresses breast cancer tumor growth

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