The catalytic diversity of RNAs

scientific article

The catalytic diversity of RNAs is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1022660640
P356DOI10.1038/NRM1647
P8608Fatcat IDrelease_dktunu2a3jckdfftghj52uggoq
P698PubMed publication ID15956979

P2093author name stringJames R Williamson
Martha J Fedor
P2860cites workEnzyme-Catalyzed Phosphoryl Transfer ReactionsQ22255662
A general two-metal-ion mechanism for catalytic RNAQ24562157
Self-cleavage of plus and minus RNA transcripts of avocado sunblotch viroidQ24631528
Peripheral regions of natural hammerhead ribozymes greatly increase their self-cleavage activityQ24679814
Capture and visualization of a catalytic RNA enzyme-product complex using crystal lattice trapping and X-ray holographic reconstructionQ27625218
The structural basis of ribosome activity in peptide bond synthesisQ27626414
Crystal structure of the ribosome at 5.5 A resolutionQ27630949
Crystal structure of a hairpin ribozyme-inhibitor complex with implications for catalysisQ27631159
Structural insights into peptide bond formationQ27639505
Transition state stabilization by a catalytic RNAQ27639765
The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavageQ27729430
Three-dimensional structure of a hammerhead ribozymeQ27730774
Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozymeQ27734150
The structural basis of hammerhead ribozyme self-cleavageQ27748930
A preorganized active site in the crystal structure of the Tetrahymena ribozymeQ27766124
Sequence elements outside the hammerhead ribozyme catalytic core enable intracellular activityQ28189633
Ribonuclease AQ28201882
The hairpin ribozyme: from crystal structure to functionQ28215410
Control of gene expression by a natural metabolite-responsive ribozymeQ28251218
RNA catalytic properties of the minimum (-)sTRSV sequenceQ28278743
The hammerhead, hairpin and VS ribozymes are catalytically proficient in monovalent cations aloneQ28288958
Autocatalytic RNA cleavage in the human beta-globin pre-mRNA promotes transcription terminationQ28295290
Crystal structure of a phage Twort group I ribozyme-product complexQ28296661
Three metal ions at the active site of the Tetrahymena group I ribozymeQ28315032
Functional involvement of G8 in the hairpin ribozyme cleavage mechanismQ28364046
Tertiary structure formation in the hairpin ribozyme monitored by fluorescence resonance energy transferQ28769589
Mechanistic characterization of the HDV genomic ribozyme: assessing the catalytic and structural contributions of divalent metal ions within a multichannel reaction mechanismQ29028221
A second catalytic metal ion in group I ribozymeQ30470964
Comparative analysis of hairpin ribozyme structures and interference dataQ30678338
The ribosome as an entropy trapQ30930830
Ions and RNA foldingQ30988822
Structure and function of the hairpin ribozymeQ33861637
Ribozyme structures and mechanismsQ34019400
Biophysical and biochemical investigations of RNA catalysis in the hammerhead ribozymeQ34149356
Crystal structure of a self-splicing group I intron with both exonsQ34324406
Thiophilic metal ion rescue of phosphorothioate interference within the Tetrahymena ribozyme P4-P6 domainQ34362185
Unusual resistance of peptidyl transferase to protein extraction proceduresQ34436822
Catalytic strategies of the hepatitis delta virus ribozymesQ34667466
The role of metal ions in RNA catalysisQ34749886
Folding and activity of the hammerhead ribozymeQ34804270
The path to perdition is paved with protonsQ34894393
Visualizing the structure and mechanism of a small nucleolytic ribozymeQ34996778
The hammerhead ribozymeQ35003643
After the ribosome structures: how does peptidyl transferase work?Q35055506
Mechanistic considerations for general acid-base catalysis by RNA: revisiting the mechanism of the hairpin ribozymeQ35071324
Peptide bond formation on the ribosome: structure and mechanismQ35165233
RNA, the first macromolecular catalyst: the ribosome is a ribozymeQ35204584
The hairpin ribozymeQ35614124
A guide to ions and RNA structureQ35670060
The structure-function dilemma of the hammerhead ribozymeQ36115496
pK(a) perturbation in genomic Hepatitis Delta Virus ribozyme catalysis evidenced by nucleotide analogue interference mappingQ38291286
Defining the catalytic metal ion interactions in the Tetrahymena ribozyme reactionQ38301567
Probing the role of metal ions in RNA catalysis: kinetic and thermodynamic characterization of a metal ion interaction with the 2'-moiety of the guanosine nucleophile in the Tetrahymena group I ribozymeQ38321270
Bond order and charge localization in nucleoside phosphorothioatesQ39493502
Metal ion interaction with cosubstrate in self-splicing of group I intronsQ39719033
Metal ions play a passive role in the hairpin ribozyme catalysed reactionQ39721199
A place in the world for RNA editingQ40401635
Two autolytic processing reactions of a satellite RNA proceed with inversion of configurationQ40515857
Mechanistic aspects of enzymatic catalysis: lessons from comparison of RNA and protein enzymesQ41550164
Tertiary structure stabilization promotes hairpin ribozyme ligationQ41686849
Identification of the hammerhead ribozyme metal ion binding site responsible for rescue of the deleterious effect of a cleavage site phosphorothioateQ41703953
Crystal structure of a group I intron splicing intermediateQ41816647
Artificial tertiary motifs stabilize trans-cleaving hammerhead ribozymes under conditions of submillimolar divalent ions and high temperaturesQ41939448
The folding of the hairpin ribozyme: dependence on the loops and the junctionQ42070485
Rescue of an abasic hairpin ribozyme by cationic nucleobases: evidence for a novel mechanism of RNA catalysisQ42675353
Folding of the natural hammerhead ribozyme is enhanced by interaction of auxiliary elements.Q43207204
Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotideQ43617727
Direct pK(a) measurement of the active-site cytosine in a genomic hepatitis delta virus ribozymeQ43721912
Catalytic roles for proton transfer and protonation in ribozymesQ43722704
Tertiary structure stability of the hairpin ribozyme in its natural and minimal forms: different energetic contributions from a ribose zipper motifQ43733420
Imidazole rescue of a cytosine mutation in a self-cleaving ribozymeQ44882244
A conformational switch controls hepatitis delta virus ribozyme catalysisQ44894635
Role of an active site guanine in hairpin ribozyme catalysis probed by exogenous nucleobase rescueQ44939516
Substrate-assisted catalysis of peptide bond formation by the ribosomeQ45099790
General acid-base catalysis in the mechanism of a hepatitis delta virus ribozymeQ45744207
Crystallization and structure determination of a hepatitis delta virus ribozyme: use of the RNA-binding protein U1A as a crystallization moduleQ45745245
Stability of hairpin ribozyme tertiary structure is governed by the interdomain junctionQ45858676
MAP kinases in meiosisQ46088503
Direct Brønsted analysis of the restoration of activity to a mutant enzyme by exogenous aminesQ46334040
Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation.Q46618026
The active site of the ribosome is composed of two layers of conserved nucleotides with distinct roles in peptide bond formation and peptide releaseQ47429251
Important contribution to catalysis of peptide bond formation by a single ionizing group within the ribosome.Q54539576
Fast Cleavage Kinetics of a Natural Hammerhead RibozymeQ58044980
Non-enzymatic cleavage and ligation of RNAs complementary to a plant virus satellite RNAQ59066021
A unique mechanism for RNA catalysis: the role of metal cofactors in hairpin ribozyme cleavageQ73603192
An unusual pH-independent and metal-ion-independent mechanism for hairpin ribozyme catalysisQ73661495
Making the most of metal ionsQ73688403
Hairpin ribozymes with four-way helical junctions mediate intracellular RNA ligationQ73998789
A single adenosine with a neutral pKa in the ribosomal peptidyl transferase centerQ74152471
A new metal ion interaction in the Tetrahymena ribozyme reaction revealed by double sulfur substitutionQ77318709
Kinetics and Mechanisms for the Cleavage and Isomerization of the Phosphodiester Bonds of RNA by Brønsted Acids and BasesQ77646667
Involvement of a cytosine side chain in proton transfer in the rate-determining step of ribozyme self-cleavageQ95751092
P433issue5
P304page(s)399-412
P577publication date2005-05-01
P1433published inNature Reviews Molecular Cell BiologyQ1573120
P1476titleThe catalytic diversity of RNAs
P478volume6

Reverse relations

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