| scholarly article | Q13442814 |
| P50 | author | Huda Zoghbi | Q1633764 |
| Olivier Lichtarge | Q61975468 | ||
| P2093 | author name string | Lin Chen | |
| Steven Andrew Baker | |||
| Peng Yu | |||
| Angela Dawn Wilkins | |||
| P2860 | cites work | Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2 | Q22337290 |
| Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation | Q24296972 | ||
| The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3 | Q24315621 | ||
| Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex | Q24324026 | ||
| MeCP2, a key contributor to neurological disease, activates and represses transcription | Q24647533 | ||
| ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome | Q27670417 | ||
| Chromatin compaction by human MeCP2. Assembly of novel secondary chromatin structures in the absence of DNA methylation | Q28177120 | ||
| The story of Rett syndrome: from clinic to neurobiology | Q28256549 | ||
| Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome | Q28257072 | ||
| Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA | Q28265233 | ||
| Distinct factors control histone variant H3.3 localization at specific genomic regions | Q28275277 | ||
| A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome | Q28504458 | ||
| MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin | Q28576622 | ||
| Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome | Q28595032 | ||
| Reorganizing the protein space at the Universal Protein Resource (UniProt) | Q29547338 | ||
| Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes | Q29616326 | ||
| Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice | Q29616328 | ||
| Reversal of neurological defects in a mouse model of Rett syndrome | Q29616452 | ||
| DNA recognition by the methyl-CpG binding domain of MeCP2. | Q31465850 | ||
| Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues | Q33240549 | ||
| HMGA1 down-regulation is crucial for chromatin composition and a gene expression profile permitting myogenic differentiation | Q33654752 | ||
| Unique physical properties and interactions of the domains of methylated DNA binding protein 2. | Q33860692 | ||
| Molecular-clinical spectrum of the ATR-X syndrome | Q34306141 | ||
| Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state. | Q35114553 | ||
| Determinants of histone H1 mobility and chromatin binding in living cells. | Q36484524 | ||
| MECP2 mutations in males. | Q36757032 | ||
| Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress. | Q37001615 | ||
| Severe congenital encephalopathy caused by MECP2 null mutations in males: central hypoxia and reduced neuronal dendritic structure. | Q37162573 | ||
| Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus | Q37223275 | ||
| Nuclear functions of the HMG proteins | Q37596093 | ||
| Retroviral cDNA integration: stimulation by HMG I family proteins | Q39597653 | ||
| DNA binding selectivity of MeCP2 due to a requirement for A/T sequences adjacent to methyl-CpG. | Q40378884 | ||
| Loss of ATRX leads to chromosome cohesion and congression defects | Q41825660 | ||
| Early progressive encephalopathy in boys and MECP2 mutations | Q41919344 | ||
| Multiple modes of interaction between the methylated DNA binding protein MeCP2 and chromatin. | Q42952032 | ||
| No correlation between phenotype and genotype in boys with a truncating MECP2 mutation | Q43074531 | ||
| ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner. | Q47407852 | ||
| The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression | Q48667829 | ||
| Pairwise Statistical Significance of Local Sequence Alignment Using Sequence-Specific and Position-Specific Substitution Matrices | Q51638339 | ||
| An explanation for another familial case of Rett syndrome: maternal germline mosaicism. | Q51756652 | ||
| Mild overexpression of MeCP2 causes a progressive neurological disorder in mice. | Q52087714 | ||
| Reversible oligonucleosome self-association: dependence on divalent cations and core histone tail domains | Q71165591 | ||
| MeCP2-chromatin interactions include the formation of chromatosome-like structures and are altered in mutations causing Rett syndrome | Q80693217 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Rett syndrome | Q917357 |
| P304 | page(s) | 984-996 | |
| P577 | publication date | 2013-02-01 | |
| P1433 | published in | Cell | Q655814 |
| P1476 | title | An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disorders | |
| P478 | volume | 152 |
| Q58608072 | A Novel Mecp2 Knock-in Model Displays Similar Behavioral Traits But Distinct Molecular Features Compared to the Mecp2-Null Mouse Implying Precision Medicine for the Treatment of Rett Syndrome |
| Q39132989 | A Novel Mutation p.A59P in N-Terminal Domain of Methyl-CpG-Binding Protein 2 Confers Phenotypic Variability in 3 Cases of Tunisian Rett Patients: Clinical Evaluations and In Silico Investigations |
| Q36676822 | A critical period of vulnerability to adolescent stress: epigenetic mediators in mesocortical dopaminergic neurons |
| Q28771505 | A de novo t(10;19)(q22.3;q13.33) leads to ZMIZ1/PRR12 reciprocal fusion transcripts in a girl with intellectual disability and neuropsychiatric alterations |
| Q36094434 | A high-resolution imaging approach to investigate chromatin architecture in complex tissues |
| Q55499199 | A mutation-led search for novel functional domains in MeCP2. |
| Q40545607 | A novel DNA-binding feature of MeCP2 contributes to Rett syndrome. |
| Q46016669 | A novel mutation R190H in the AT-hook 1 domain of MeCP2 identified in an atypical Rett syndrome. |
| Q37159793 | A/T Run Geometry of B-form DNA Is Independent of Bound Methyl-CpG Binding Domain, Cytosine Methylation and Flanking Sequence. |
| Q89738675 | Absence of MeCP2 binding to non-methylated GT-rich sequences in vivo |
| Q48156601 | Affective dysfunction in a mouse model of Rett syndrome: Therapeutic effects of environmental stimulation and physical activity |
| Q58697752 | Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2 |
| Q46022392 | An RNA interference screen identifies druggable regulators of MeCP2 stability. |
| Q33983659 | Analysis of neonatal brain lacking ATRX or MeCP2 reveals changes in nucleosome density, CTCF binding and chromatin looping |
| Q56894959 | Apparent bias toward long gene misregulation in MeCP2 syndromes disappears after controlling for baseline variations |
| Q35595728 | Autism spectrum disorders: emerging mechanisms and mechanism-based treatment. |
| Q47636137 | Biotin tagging of MeCP2 in mice reveals contextual insights into the Rett syndrome transcriptome. |
| Q42030002 | By hook or by crook: multifaceted DNA-binding properties of MeCP2. |
| Q34890354 | Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis involving the Notch signalling pathway |
| Q37534398 | Chromatin context and ncRNA highlight targets of MeCP2 in brain |
| Q58794852 | Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2 |
| Q38375116 | Clinical and biological progress over 50 years in Rett syndrome. |
| Q46490716 | Clinical, Molecular, and Computational Analysis in Patients With a Novel Double Mutation and a New Synonymous Variant in MeCP2: Report of the First Missense Mutation Within the AT-hook1 Cluster in Rett Syndrome |
| Q33907569 | Computational and experimental approaches to reveal the effects of single nucleotide polymorphisms with respect to disease diagnostics |
| Q37626764 | DNA methylation and childhood maltreatment: from animal models to human studies |
| Q37550088 | DNA methylation in the gene body influences MeCP2-mediated gene repression |
| Q34103956 | DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution |
| Q26829214 | DNA modifications: function and applications in normal and disease States |
| Q36851443 | De novo truncating variants in the AHDC1 gene encoding the AT-hook DNA-binding motif-containing protein 1 are associated with intellectual disability and developmental delay |
| Q34466731 | Disruption of DNA-methylation-dependent long gene repression in Rett syndrome |
| Q55496089 | Early alteration of epigenetic-related transcription in Huntington's disease mouse models. |
| Q38662646 | Emerging roles of ATRX in cancer |
| Q37647937 | Epigenetics and the regulation of stress vulnerability and resilience |
| Q37249145 | Epigenetics, autism spectrum, and neurodevelopmental disorders. |
| Q55499041 | Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity. |
| Q39126183 | Functional assessment of MeCP2 in Rett syndrome and cancers of breast, colon, and prostate |
| Q88867776 | Genome-wide distribution of linker histone H1.0 is independent of MeCP2 |
| Q92399774 | Genome-wide transcriptomic and proteomic studies of Rett syndrome mouse models identify common signaling pathways and cellular functions as potential therapeutic targets |
| Q37372395 | Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior. |
| Q37598427 | Human pluripotent stem cell models of autism spectrum disorder: emerging frontiers, opportunities, and challenges towards neuronal networks in a dish |
| Q36049921 | Karyopherin α 3 and karyopherin α 4 proteins mediate the nuclear import of methyl-CpG binding protein 2 |
| Q38992291 | Lessons learned from studying syndromic autism spectrum disorders |
| Q93187579 | Leveraging the genetic basis of Rett syndrome to ascertain pathophysiology |
| Q37681389 | Lipid rafts: a signaling platform linking cholesterol metabolism to synaptic deficits in autism spectrum disorders |
| Q30369619 | Loss of MeCP2 in Parvalbumin-and Somatostatin-Expressing Neurons in Mice Leads to Distinct Rett Syndrome-like Phenotypes |
| Q48654868 | Loss of neuronal 3D chromatin organization causes transcriptional and behavioural deficits related to serotonergic dysfunction |
| Q26799760 | MECP2 disorders: from the clinic to mice and back |
| Q41701539 | MECP2 impairs neuronal structure by regulating KIBRA. |
| Q36628976 | MECP2 missense mutations outside the canonical MBD and TRD domains in males with intellectual disability |
| Q38853829 | MECP2, a multi-talented modulator of chromatin architecture |
| Q33957193 | Maintaining genome stability in the nervous system |
| Q50068577 | MeCP2 AT-Hook1 mutations in patients with intellectual disability and/or schizophrenia disrupt DNA binding and chromatin compaction in vitro |
| Q50302685 | MeCP2 Binding Cooperativity Inhibits DNA Modification-Specific Recognition. |
| Q33809732 | MeCP2 Promotes Gastric Cancer Progression Through Regulating FOXF1/Wnt5a/β-Catenin and MYOD1/Caspase-3 Signaling Pathways |
| Q48841317 | MeCP2 R168X male and female mutant mice exhibit Rett-like behavioral deficits |
| Q45303510 | MeCP2 and CTCF: enhancing the cross-talk of silencers |
| Q35566873 | MeCP2 binds to non-CG methylated DNA as neurons mature, influencing transcription and the timing of onset for Rett syndrome |
| Q97650823 | MeCP2 links heterochromatin condensates and neurodevelopmental disease |
| Q83224338 | MeCP2 nuclear dynamics in live neurons results from low and high affinity chromatin interactions |
| Q33732160 | MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain. |
| Q36008270 | MeCP2 regulates the timing of critical period plasticity that shapes functional connectivity in primary visual cortex |
| Q50993055 | MeCP2, A Modulator of Neuronal Chromatin Organization Involved in Rett Syndrome. |
| Q41228798 | MeCP2, a target of miR-638, facilitates gastric cancer cell proliferation through activation of the MEK1/2-ERK1/2 signaling pathway by upregulating GIT1. |
| Q55002845 | MeCP2-mediated epigenetic regulation in senescent endothelial progenitor cells. |
| Q90133350 | MeCP2: A Critical Regulator of Chromatin in Neurodevelopment and Adult Brain Function |
| Q33878027 | Methyl-CpG binding domain protein 1 regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner. |
| Q28271310 | Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects |
| Q30357465 | Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression |
| Q89602927 | Nuclear receptor corepressors in intellectual disability and autism |
| Q39132984 | Phenotypic variability in two infants sharing the same MECP2 mutation: evidence of chromosomal rearrangements and high sister-chromatid exchange levels in Rett syndrome |
| Q41919307 | Radically truncated MeCP2 rescues Rett syndrome-like neurological defects. |
| Q35699206 | Reading the unique DNA methylation landscape of the brain: Non-CpG methylation, hydroxymethylation, and MeCP2. |
| Q36540413 | Reduction of aberrant NF-κB signalling ameliorates Rett syndrome phenotypes in Mecp2-null mice |
| Q30378674 | Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome. |
| Q38194967 | Rett syndrome and MeCP2. |
| Q55312256 | Rett syndrome from bench to bedside: recent advances. |
| Q89948341 | Rett syndrome-causing mutations compromise MeCP2-mediated liquid-liquid phase separation of chromatin |
| Q38366899 | Rett syndrome: a complex disorder with simple roots |
| Q50422613 | Rett syndrome: a neurological disorder with metabolic components. |
| Q28088283 | Rett syndrome: disruption of epigenetic control of postnatal neurological functions |
| Q88609435 | Rett syndrome: insights into genetic, molecular and circuit mechanisms |
| Q33915332 | Rett-causing mutations reveal two domains critical for MeCP2 function and for toxicity in MECP2 duplication syndrome mice |
| Q28909718 | SUMOylation of MeCP2 is essential for transcriptional repression and hippocampal synapse development |
| Q36765190 | Sequence features accurately predict genome-wide MeCP2 binding in vivo. |
| Q42393391 | Sequence-specific DNA binding by AT-hook motifs in MeCP2. |
| Q57462271 | Species and cell-type properties of classically defined human and rodent neurons and glia |
| Q92587258 | Structural investigation of Rett-inducing MeCP2 mutations |
| Q33737461 | The Crucial Role of DNA Methylation and MeCP2 in Neuronal Function |
| Q53158422 | The MECP2 variant c.925C>T (p.Arg309Trp) causes intellectual disability in both males and females without classic features of Rett syndrome. |
| Q90401570 | The array of clinical phenotypes of males with mutations in Methyl-CpG binding protein 2 |
| Q90202348 | The distinct methylation landscape of maturing neurons and its role in Rett syndrome pathogenesis |
| Q40756726 | The extended AT-hook is a novel RNA binding motif. |
| Q38220786 | The neuronal activity-driven transcriptome. |
| Q39296630 | Transcribing the connectome: roles for transcription factors and chromatin regulators in activity-dependent synapse development |
| Q37281126 | Transcriptional regulation of the MET receptor tyrosine kinase gene by MeCP2 and sex-specific expression in autism and Rett syndrome |
| Q96610148 | Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain |
| Q64081306 | Transcriptomic Analysis of Mutant Mice Reveals Differentially Expressed Genes and Altered Mechanisms in Both Blood and Brain |
| Q38307079 | Unusual characteristics of the DNA binding domain of epigenetic regulatory protein MeCP2 determine its binding specificity |
| Q42833216 | Up-regulation of HP1γ expression during neuronal maturation promotes axonal and dendritic development in mouse embryonic neocortex |
| Q90173981 | Variant Profile of MECP2 Gene in Sri Lankan Patients with Rett Syndrome |
| Q58700147 | genetically interacts with the ALS-associated orthologue and mediates its toxicity |
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