Unusual characteristics of the DNA binding domain of epigenetic regulatory protein MeCP2 determine its binding specificity

scientific article published on 23 May 2014

Unusual characteristics of the DNA binding domain of epigenetic regulatory protein MeCP2 determine its binding specificity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/BI500424Z
P932PMC publication ID4045320
P698PubMed publication ID24828757
P5875ResearchGate publication ID262343418

P50authorSergei KhrapunovQ68486110
John GreallyQ42667137
P2093author name stringChristopher Warren
Michael Brenowitz
Esther R Berko
Huiyong Cheng
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An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disordersQ36810668
Impaired in vivo binding of MeCP2 to chromatin in the absence of its DNA methyl-binding domainQ36814262
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Genetic and epigenetic defects in mental retardation.Q37259024
MeCP2: structure and functionQ37843467
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Equilibrium binding assays reveal the elevated stoichiometry and salt dependence of the interaction between full-length human sex-determining region on the Y chromosome (SRY) and DNA.Q38291508
Intrinsic disorder and autonomous domain function in the multifunctional nuclear protein, MeCP2.Q38303577
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MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system.Q40680118
Nonspecific interactions of Escherichia coli RNA polymerase with native and denatured DNA: differences in the binding behavior of core and holoenzymeQ40897137
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16 Analysis of equilibrium and kinetic measurements to determine thermodynamic origins of stability and specificity and mechanism of formation of site-specific complexes between proteins and helical DNAQ44249816
Thermodynamic signature of GCN4-bZIP binding to DNA indicates the role of water in discriminating between the AP-1 and ATF/CREB sitesQ45100707
Kinetic and thermodynamic evidence for flipping of a methyl-CpG binding domain on methylated DNA.Q47920943
Methylation-dependent and -independent genomic targeting principles of the MBD protein family.Q51071218
DNA and protein footprinting analysis of the modulation of DNA binding by the N-terminal domain of the Saccharomyces cerevisiae TATA binding protein.Q51978961
DNA conformational changes associated with the cooperative binding of cI-repressor of bacteriophage lambda to OR.Q52362573
Thermodynamics of the interactions of lac repressor with variants of the symmetric lac operator: effects of converting a consensus site to a non-specific site.Q52525478
Interpretation of monovalent and divalent cation effects on the lac repressor-operator interactionQ52805920
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MeCP2 Rett mutations affect large scale chromatin organization.Q52893532
P433issue21
P407language of work or nameEnglishQ1860
P304page(s)3379-3391
P577publication date2014-05-23
P1433published inBiochemistryQ764876
P1476titleUnusual characteristics of the DNA binding domain of epigenetic regulatory protein MeCP2 determine its binding specificity
P478volume53

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cites work (P2860)
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