Regulation by the autophosphorylation site in overexpressed pp60c-src

scientific article published on October 1988

Regulation by the autophosphorylation site in overexpressed pp60c-src is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.8.10.4541
P932PMC publication ID365532
P698PubMed publication ID2460746
P5875ResearchGate publication ID20694881

P2093author name stringD Shalloway
P J Johnson
T E Kmiecik
P2860cites workReplacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucoseQ24299251
A novel viral oncogene with structural similarity to phospholipase CQ28307371
Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus.Q30448511
Monoclonal antibodies to Rous sarcoma virus pp60src react with enzymatically active cellular pp60src of avian and mammalian originQ30452279
Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylationQ33931404
Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylationQ34166097
In vivo effect of sodium orthovanadate on pp60c-src kinaseQ36837132
Phosphorylation of the transforming protein of Rous sarcoma virus: direct demonstration of phosphorylation of serine 17 and identification of an additional site of tyrosine phosphorylation in p60v-src of Prague Rous sarcoma virusQ36864201
Low level of cellular protein phosphorylation by nontransforming overproduced p60c-srcQ36888845
Overexpressed pp60c-src can induce focus formation without complete transformation of NIH 3T3 cellsQ36888885
Restriction of the in vitro and in vivo tyrosine protein kinase activities of pp60c-src relative to pp60v-srcQ36894965
Dephosphorylation or antibody binding to the carboxy terminus stimulates pp60c-srcQ36901811
Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma virusesQ36909345
Structurally and functionally modified forms of pp60v-src in Rous sarcoma virus-transformed cell lysatesQ36945448
Forms of pp60v-src isolated from Rous sarcoma virus-transformed cells.Q40132338
Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domainQ42808327
Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-srcQ44049774
A tail of two src's: mutatis mutandisQ45248634
Mutagenesis of Fujinami Sarcoma Virus: Evidence that tyrosine phosphorylation of P130gag-fps modulates its biological activityQ45796584
Local mutagenesis of Rous sarcoma virus: The major sites of tyrosine and serine phosphorylation of p60src are dispensable for transformationQ45797801
The stimulation of pp60v-src kinase activity by vanadate in intact cells accompanies a new phosphorylation state of the enzymeQ53551151
Phosphorylation of tyrosine-416 is not required for the transforming properties and kinase activity of pp60v-src.Q53560402
Avian pp60c-src is more active when expressed in yeast than in vertebrate fibroblastsQ69026384
A mutation at the major phosphotyrosine in pp60v-src alters oncogenic potentialQ72741286
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectoverexpressionQ61643320
P304page(s)4541-4546
P577publication date1988-10-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleRegulation by the autophosphorylation site in overexpressed pp60c-src
P478volume8

Reverse relations

cites work (P2860)
Q49018988A comparative study of the phosphotyrosyl phosphatase specificity of protein phosphatase type 2A and phosphotyrosyl phosphatase type 1B using phosphopeptides and the phosphoproteins p50/HS1, c-Fgr and Lyn.
Q22253266A phosphotyrosine displacement mechanism for activation of Src by PTPalpha
Q30195267Activation of c-Src in cells bearing v-Crk and its suppression by Csk
Q34207678Activation of pro-survival CaMK4β/CREB and pro-death MST1 signaling at early and late times during a mouse model of prion disease
Q34341764Activation of the Lck tyrosine protein kinase by hydrogen peroxide requires the phosphorylation of Tyr-394.
Q41699923Altered tyrosine 527 phosphorylation and mitotic activation of p60c-src
Q35807271Angiotensin II induces epithelial-to-mesenchymal transition in renal epithelial cells through reactive oxygen species/Src/caveolin-mediated activation of an epidermal growth factor receptor-extracellular signal-regulated kinase signaling pathway
Q37582902Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases
Q30194001Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527.
Q40807012Attenuation of adhesion-dependent signaling and cell spreading in transformed fibroblasts lacking protein tyrosine phosphatase-1B.
Q34323982Autophosphorylation: a salient feature of protein kinases
Q37210990Calcium-dependent increase in tyrosine kinase activity stimulated by angiotensin II
Q41370986Cell spreading in Colo 201 by staurosporin is alpha 3 beta 1 integrin-mediated with tyrosine phosphorylation of Src and tensin
Q40952373Cellular consequences of thrombin-receptor activation
Q67663346Characterization of purified pp60c-src protein tyrosine kinase from human platelets
Q37732353Coinfection of insect cells with recombinant baculovirus expressing pp60v-src results in the activation of a serine-specific protein kinase pp90rsk
Q27618507Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor
Q29622946Crystal structure of cyclin-dependent kinase 2
Q30450251Differential Modulation of Plasminogen Activator Gene Expression by Oncogene-Encoded Protein Tyrosine Kinases
Q35715849EGFR signaling promotes TGFβ-dependent renal fibrosis
Q30195067En bloc substitution of the Src homology region 2 domain activates the transforming potential of the c-Abl protein tyrosine kinase
Q24307555Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit
Q34170326Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development
Q41099653High-level expression of human c-Src can cause a spherical morphology without loss of anchorage-dependent growth of NIH 3T3 cells
Q42826789Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
Q34994048Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling
Q33773066In vitro membrane reconstitution of the T-cell receptor proximal signaling network
Q28646526Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase
Q35277738Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation
Q42795961Lithium suppresses motility and invasivity of v-src-transformed cells by glutathione-dependent activation of phosphotyrosine phosphatases
Q39644339Loss of tyrosine phosphatase‐dependent inhibition promotes activation of tyrosine kinase c‐Src in detached pancreatic cells
Q36709950Macrophage colony-stimulating factor-induced tyrosine phosphorylation of c-fms proteins expressed in FDC-P1 and BALB/c 3T3 cells
Q36757260Mutation of amino acids in pp60c-src that are phosphorylated by protein kinases C and A.
Q36675443Myristylation is required for Tyr-527 dephosphorylation and activation of pp60c-src in mitosis
Q36277376NMR analysis of regioselectivity in dephosphorylation of a triphosphotyrosyl dodecapeptide autophosphorylation site of the insulin receptor by a catalytic fragment of LAR phosphotyrosine phosphatase
Q28280361Non-structural protein 3 of hepatitis C virus inhibits phosphorylation mediated by cAMP-dependent protein kinase
Q37113935Oncoprotein Kinases in Mitosis
Q64084257Parathyroid hormone-related protein induces fibronectin up-regulation in rat mesangial cells through reactive oxygen species/Src/EGFR signaling
Q58388140Phosphorylation and activation of p40 tyrosine kinase by casein kinase-1
Q41597803Purification and biochemical characterization of non-myristoylated recombinant pp60c-src kinase
Q36676794Redistribution of activated pp60c-src to integrin-dependent cytoskeletal complexes in thrombin-stimulated platelets
Q30442455Regulation of the oncogenic activity of the cellular src protein requires the correct spacing between the kinase domain and the C-terminal phosphorylated tyrosine (Tyr-527)
Q40696751Role for cellular Src kinase in myoblast proliferation
Q36676458SH1 domain autophosphorylation of P210 BCR/ABL is required for transformation but not growth factor independence
Q30167497SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading
Q30195559Selective binding of activated pp60c-src by an immobilized synthetic phosphopeptide modeled on the carboxyl terminus of pp60c-src
Q28391160Spatiotemporal regulation of Src and its substrates at invadosomes
Q41904978Src kinase modulates the apoptotic p53 pathway by altering HIPK2 localization.
Q28296324Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases
Q36757700Structural differences between repressed and derepressed forms of p60c-src
Q30194837Suppression of c-Src Activity by C-Terminal Src Kinase Involves the c-Src SH2 and SH3 Domains: Analysis with Saccharomyces cerevisiae
Q57071339The Purification and Characterization of the Catalytic Domain of Src Expressed in Schizosaccharomyces Pombe. Comparison of Unphosphorylated and Tyrosine Phosphorylated Species
Q40454708The regulation of tyrosine kinase signalling pathways by growth factor and G-protein-coupled receptors.
Q71645630The synthesis and use of pp60src-related peptides and phosphopeptides as substrates for enzymatic phosphorylation studies
Q40487537The when and how of Src regulation
Q34907796Tyrosine 416 is phosphorylated in the closed, repressed conformation of c-Src
Q41100840Vanadate-induced gene expression in mouse C127 cells: roles of oxygen derived active species
Q38520262Vanadium Compounds as Pro-Inflammatory Agents: Effects on Cyclooxygenases
Q35163571c‐Src and Mitosis
Q36759826pp60c-src variants containing lesions that affect phosphorylation at tyrosines 416 and 527.