Identification of a Salmonella typhimurium invasion locus by selection for hyperinvasive mutants

scientific article published on March 1, 1992

Identification of a Salmonella typhimurium invasion locus by selection for hyperinvasive mutants is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode1992PNAS...89.1847L
P356DOI10.1073/PNAS.89.5.1847
P953full work available at URLhttps://europepmc.org/articles/PMC48550
https://europepmc.org/articles/PMC48550?pdf=render
P932PMC publication ID48550
P698PubMed publication ID1311853
P5875ResearchGate publication ID21843561

P50authorBrad D. JonesQ71284617
P2093author name stringS. Falkow
C. A. Lee
P2860cites workPhage P22 tail protein: gene and amino acid sequenceQ48402215
Studies on early association of Salmonella typhimurium with intestinal mucosa in vivo and in vitro: relationship to virulenceQ50194415
Peroxidase-antiperoxidase and immunogold labeling of Salmonella typhimurium and Salmonella choleraesuis var kunzendorf in tissues of experimentally infected swineQ50465559
Stability of ColE1-like and pBR322-like plasmids in Escherichia coli.Q54339151
The construction of a cloning vector designed for gene replacement in Bordetella pertussis.Q54438784
The use of transposon TnphoA to detect genes for cell envelope proteins subject to a common regulatory stimulus. Analysis of osmotically regulated genes in Escherichia coli.Q54764885
Reduced superhelicity of plasmid DNA produced by the rho-15 mutation in Escherichia coli.Q54776408
Gentamicin antibacterial activity in the presence of human polymorphonuclear leukocytesQ24597159
A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coliQ28280711
The ability of Salmonella to enter mammalian cells is affected by bacterial growth stateQ33616743
Penetration of human intestinal epithelial cells by Salmonella: molecular cloning and expression of Salmonella typhi invasion determinants in Escherichia coliQ34288319
Cloning and molecular characterization of genes whose products allow Salmonella typhimurium to penetrate tissue culture cellsQ34298444
Electron microscope studies of experimental Salmonella infection. I. Penetration into the intestinal epithelium by Salmonella typhimuriumQ35972318
A novel rho promoter::Tn10 mutation suppresses and ftsQ1(Ts) missense mutation in an essential Escherichia coli cell division gene by a mechanism not involving polarity suppressionQ36125575
Negative regulatory loci coupling flagellin synthesis to flagellar assembly in Salmonella typhimuriumQ36143407
Alkaline phosphatase fusions: sensors of subcellular locationQ36157660
Penetration of Salmonella through a polarized Madin-Darby canine kidney epithelial cell monolayerQ36219136
Genetic analysis of a temperature-sensitive Salmonella typhimurium rho mutant with an altered rho-associated polycytidylate-dependent adenosine triphosphatase activity.Q36307025
Blue ghosts: a new method for isolating amber mutants defective in essential genes of Escherichia coliQ36320176
Salmonella typhimurium mutants generally defective in chemotaxisQ36576231
Expression of Salmonella typhimurium genes required for invasion is regulated by changes in DNA supercoilingQ36984314
Anaerobiosis, type 1 fimbriae, and growth phase are factors that affect invasion of HEp-2 cells by Salmonella typhimuriumQ36985210
Evidence for two genetic loci in Yersinia enterocolitica that can promote invasion of epithelial cells.Q37004636
TnphoA: a transposon probe for protein export signalsQ37557281
DNA supercoiling and environmental regulation of gene expression in pathogenic bacteriaQ37647700
Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccinesQ39513114
Polarity suppressors defective in transcription termination at the attenuator of the tryptophan operon of Escherichia coli have altered rho factorQ39789419
DNA supercoiling and the anaerobic and growth phase regulation of tonB gene expression.Q39953508
Autogenous regulation of the gene for transcription termination factor rho in Escherichia coli: localization and function of its attenuatorsQ39967538
Anaerobic growth of Salmonella typhimurium results in increased uptake by Henle 407 epithelial and mouse peritoneal cells in vitro and repression of a major outer membrane proteinQ40149767
A single genetic locus encoded by Yersinia pseudotuberculosis permits invasion of cultured animal cells by Escherichia coli K-12.Q41524335
Salmonella interactions with polarized human intestinal Caco-2 epithelial cellsQ41715988
New derivatives of transposon Tn5 suitable for mobilization of replicons, generation of operon fusions and induction of genes in gram-negative bacteriaQ41955927
Cytopathogenic effect of Salmonella typhi GIFU 10007 on M cells of murine ileal Peyer's patches in ligated ileal loops: an ultrastructural studyQ42522319
Identification and characterization of TnphoA mutants of Salmonella that are unable to pass through a polarized MDCK epithelial cell monolayerQ46076466
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectSalmonella TyphimuriumQ166491
bacterial genesQ66684857
P304page(s)1847-1851
P577publication date1992-03-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleIdentification of a Salmonella typhimurium invasion locus by selection for hyperinvasive mutants
P478volume89

Reverse relations

cites work (P2860)
Q588278427.2 Genetic Approaches to the Study of Pathogenic Salmonellae
Q33992012A HilA-independent pathway to Salmonella typhimurium invasion gene transcription
Q52589126A Nonpyroptotic IFN-γ-Triggered Cell Death Mechanism in Nonphagocytic Cells Promotes Salmonella Clearance In Vivo.
Q36103190A PhoP-repressed gene promotes Salmonella typhimurium invasion of epithelial cells
Q33991633A periplasmic D-alanyl-D-alanine dipeptidase in the gram-negative bacterium Salmonella enterica
Q39831028An Edwardsiella tarda strain containing a mutation in a gene with homology to shlB and hpmB is defective for entry into epithelial cells in culture
Q36950718An unusual pagC::TnphoA mutation leads to an invasion- and virulence-defective phenotype in Salmonellae
Q34002323Analysis of virulence of clinical isolates of Salmonella enteritidis in vivo and in vitro
Q59042634Application of Molecular Approaches for Understanding Foodborne Salmonella Establishment in Poultry Production
Q39821760Association with MDCK epithelial cells by Salmonella typhimurium is reduced during utilization of carbohydrates
Q58049564Bimodal Expression of the Salmonella Typhimurium spv Operon
Q39821358Biological and genetic characterization of TnphoA mutants of Salmonella typhimurium TML in the context of gastroenteritis
Q33767387Caveolae-mediated entry of Salmonella typhimurium into senescent nonphagocytotic host cells
Q33753667Cell-contact-stimulated formation of filamentous appendages by Salmonella typhimurium does not depend on the type III secretion system encoded by Salmonella pathogenicity island 1.
Q35593631Characterization of the Salmonella typhimurium pagC/pagD chromosomal region.
Q44872560Characterization of two novel regulatory genes affecting Salmonella invasion gene expression
Q35030944Chloramphenicol and tetracycline decrease motility and increase invasion and attachment gene expression in specific isolates of multidrug-resistant Salmonella enterica serovar Typhimurium
Q41504292Cloning and molecular characterization of a gene involved in Salmonella adherence and invasion of cultured epithelial cells
Q40874006Cognate gene clusters govern invasion of host epithelial cells by Salmonella typhimurium and Shigella flexneri
Q39844957Comparative genetics of the inv-spa invasion gene complex of Salmonella enterica
Q40061508Comparison of Salmonella enterica subspecies enterica serovar Typhimurium isolates from dairy cattle and humans using in vitro assays of virulence
Q50042512Comparisons of Salmonella conjugation and virulence gene hyperexpression mediated by rumen protozoa from domestic and exotic ruminants
Q32060804Construction and characterization of a partial Mycobacterium tuberculosis cDNA library of genes expressed at reduced oxygen tension
Q35493173Contribution of fimbrial operons to attachment to and invasion of epithelial cell lines by Salmonella typhimurium.
Q33701821Control of type III protein secretion using a minimal genetic system
Q40017377Coordinated regulation of expression of Salmonella pathogenicity island 1 and flagellar type III secretion systems by ATP-dependent ClpXP protease
Q39572666Counterselectable markers: untapped tools for bacterial genetics and pathogenesis
Q39296439Deletions in the pyruvate pathway of Salmonella Typhimurium alter SPI1-mediated gene expression and infectivity
Q36814156Distribution, gene sequence and expression in vivo of the plasmid encoded fimbrial antigen of Salmonella serotype Enteritidis
Q36833010DsbA and MgrB regulate steA expression through the two-component system PhoQ/PhoP in Salmonella enterica
Q40269722Effects of multiplicity of infection, bacterial protein synthesis, and growth phase on adhesion to and invasion of human cell lines by Salmonella typhimurium.
Q50119756Efficient amplification of multiple transposon-flanking sequences
Q33750433Environmental regulation of Salmonella typhi invasion-defective mutants
Q33953109Epitope tagging of chromosomal genes in Salmonella
Q64268775Everything You Always Wanted to Know About Type 1 Fimbriae, but Were Afraid to Ask
Q35555222Exposure to low oxygen tension and increased osmolarity enhance the ability of Mycobacterium avium to enter intestinal epithelial (HT-29) cells.
Q33946895Exposure to rumen protozoa leads to enhancement of pathogenicity of and invasion by multiple-antibiotic-resistant Salmonella enterica bearing SGI1.
Q47694324Expression and transcriptional control of the Salmonella typhimurium Ipf fimbrial operon by phase variation
Q50119832Expression of the hilA Salmonella typhimurium gene in a poultry Salm. enteritidis isolate in response to lactate and nutrients
Q41481361Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes.
Q38305847FNR is a global regulator of virulence and anaerobic metabolism in Salmonella enterica serovar Typhimurium (ATCC 14028s).
Q36747272Formate acts as a diffusible signal to induce Salmonella invasion
Q50282354Functional Analysis of the Chaperone-Usher Fimbrial Gene Clusters of Salmonella enterica serovar Typhi
Q41394091Functional analysis of the Salmonella typhimurium invasion genes invl and invJ and identification of a target of the protein secretion apparatus encoded in the inv locus
Q41911664Fur regulates expression of the Salmonella pathogenicity island 1 type III secretion system through HilD.
Q36669927Genetic map of Salmonella typhimurium, edition VIII
Q33301871Genome-wide screen of Salmonella genes expressed during infection in pigs, using in vivo expression technology
Q33997017Hha is a negative modulator of transcription of hilA, the Salmonella enterica serovar Typhimurium invasion gene transcriptional activator
Q35365637HilA-like regulators in Escherichia coli pathotypes: the YgeH protein from the enteroaggregative strain 042
Q49597228HilE Regulates HilD by Blocking DNA Binding in Salmonella enterica serovar Typhimurium
Q34714166HilE interacts with HilD and negatively regulates hilA transcription and expression of the Salmonella enterica serovar Typhimurium invasive phenotype.
Q50075579Human milk glycoproteins inhibit the adherence of Salmonella typhimurium to HeLa cells
Q34536508Identification and characterization of a Salmonella typhimurium oxygen-regulated gene required for bacterial internalization.
Q33612050Identification and molecular characterization of a Salmonella typhimurium gene involved in triggering the internalization of salmonellae into cultured epithelial cells
Q24537566Identification of CsrC and characterization of its role in epithelial cell invasion in Salmonella enterica serovar Typhimurium
Q33727694Identification of a novel Salmonella invasion locus homologous to Shigella ipgDE
Q37441337Identification of a pathogenicity island required for Salmonella survival in host cells
Q48014401Identification of csrR/csrS, a genetic locus that regulates hyaluronic acid capsule synthesis in group A Streptococcus
Q45252292Identification of genes that are dispensable for animal infection by Salmonella typhimurium
Q35599750Identification of two targets of the type III protein secretion system encoded by the inv and spa loci of Salmonella typhimurium that have homology to the Shigella IpaD and IpaA proteins
Q34008406In vitro and in vivo assessment of Salmonella enterica serovar Typhimurium DT104 virulence
Q34045825Inhibition of Salmonella host cell invasion by dimethyl sulfide
Q33750512Inoculum composition and Salmonella pathogenicity island 1 regulate M-cell invasion and epithelial destruction by Salmonella typhimurium.
Q40921983Insertional inactivation of the Listeria monocytogenes cheYA operon abolishes response to oxygen gradients and reduces the number of flagella
Q38988857Interferon-γ in Salmonella pathogenesis: New tricks for an old dog.
Q33992712InvF is required for expression of genes encoding proteins secreted by the SPI1 type III secretion apparatus in Salmonella typhimurium
Q36946395Invasion by Salmonella typhimurium is affected by the direction of flagellar rotation
Q35689233Involvement of a Salmonella genomic island 1 gene in the rumen protozoan-mediated enhancement of invasion for multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium
Q41489386Models of invasion of enteric and periodontal pathogens into epithelial cells: a comparative analysis
Q35967361Molecular and functional characterization of the Salmonella typhimurium invasion genes invB and invC: homology of InvC to the F0F1 ATPase family of proteins
Q33558343Molecular basis of the interaction of Salmonella with the intestinal mucosa.
Q41057366Molecular genetic bases of Salmonella entry into host cells
Q36087007Molecular, functional, and evolutionary analysis of sequences specific to Salmonella
Q39522443Motility and chemotaxis in tissue penetration of oral epithelial cell layers by Treponema denticola
Q50147335Mouse virulence gene A (mviA+) is a pleiotropic regulator of gene expression in Salmonella typhimurium
Q39538569Multiple factors independently regulate hilA and invasion gene expression in Salmonella enterica serovar typhimurium
Q40501335Mutagenesis and variant selection in Salmonella.
Q39567676Mutations in Salmonella pathogenicity island 2 (SPI2) genes affecting transcription of SPI1 genes and resistance to antimicrobial agents
Q38360033Mutations in the cytoplasmic domain of the integrin beta1 chain indicate a role for endocytosis factors in bacterial internalization
Q90249639Mycobacterium tuberculosis Dissemination Plays a Critical Role in Pathogenesis
Q77695928New molecular techniques and the study of infection
Q34000197Orchestration of neutrophil movement by intestinal epithelial cells in response to Salmonella typhimurium can be uncoupled from bacterial internalization.
Q39764690Pathogenicity of dodecyltrimethylammonium chloride-resistant Salmonella enterica
Q35113085Perspectives on the use of organic acids and short chain fatty acids as antimicrobials
Q33755510Physical limitations on Salmonella typhi entry into cultured human intestinal epithelial cells
Q40270371Prolonged inhibition of bacterial protein synthesis abolishes Salmonella invasion
Q37439277Quantitative assessment of cytosolic Salmonella in epithelial cells.
Q39792027Regulation of Salmonella enterica pathogenicity island 1 by DNA adenine methylation
Q39517248Regulation of Salmonella enterica serovar typhimurium invasion genes by csrA.
Q26781384Regulatory principles governing Salmonella and Yersinia virulence
Q34734272Requirement for exported proteins in secretion through the invasion-associated type III system of Salmonella typhimurium.
Q41990605Respective roles of culturable and viable-but-nonculturable cells in the heterogeneity of Salmonella enterica serovar typhimurium invasiveness
Q34192742Role of Cross Talk in Regulating the Dynamic Expression of the FlagellarSalmonellaPathogenicity Island 1 and Type 1 Fimbrial Genes
Q61809795Role of CsrA in stress responses and metabolism important for Salmonella virulence revealed by integrated transcriptomics
Q35567520Role of SefA subunit protein of SEF14 fimbriae in the pathogenesis of Salmonella enterica serovar Enteritidis
Q39526317Roles of hilC and hilD in regulation of hilA expression in Salmonella enterica serovar Typhimurium
Q35662912RtsA and RtsB coordinately regulate expression of the invasion and flagellar genes in Salmonella enterica serovar Typhimurium.
Q41502444Ruffles induced by Salmonella and other stimuli direct macropinocytosis of bacteria
Q33859408Salmonella Pathogenesis and Processing of Secreted Effectors by Caspase-3
Q40389974Salmonella Persistence in Tomatoes Requires a Distinct Set of Metabolic Functions Identified by Transposon Insertion Sequencing.
Q49923839Salmonella Typhimurium increases functional PD-L1 synergistically with IFNγ in intestinal epithelial cells via Salmonella Pathogenicity Island-2.
Q31172548Salmonella enterica Serovar Typhi conceals the invasion-associated type three secretion system from the innate immune system by gene regulation
Q34336985Salmonella enterica serovar Typhimurium skills to succeed in the host: virulence and regulation
Q36933192Salmonella enterica serovar gallinarum requires ppGpp for internalization and survival in animal cells
Q34005208Salmonella enterica serovar typhimurium invasion is repressed in the presence of bile
Q37099435Salmonella enterica serovar typhimurium strains with regulated delayed attenuation in vivo
Q50119693Salmonella enteritidis hilA gene fusion response after incubation in spent media from either S. enteritidis or a poultry Lactobacillus strain
Q50132044Salmonella meningitis in children in far north Queensland
Q33591947Salmonella pathogenicity island 1-independent induction of apoptosis in infected macrophages by Salmonella enterica serotype typhimurium
Q35126521Schistosoma-associated Salmonella resist antibiotics via specific fimbrial attachments to the flatworm
Q50078109Sensing by bacterial regulatory systems in host and non-host environments
Q24797519Serratia marcescens internalization and replication in human bladder epithelial cells
Q50123614Short-chain fatty acids affect cell-association and invasion of HEp-2 cells by Salmonella typhimurium
Q50120935Short-chain volatile fatty acids modulate the expression of the hilA and invF genes of Salmonella typhimurium
Q43194983Sigma32-mediated negative regulation of Salmonella pathogenicity island 1 expression
Q35567150Simultaneous prevention of glutamine synthesis and high-affinity transport attenuates Salmonella typhimurium virulence
Q83232366Single cell, super-resolution imaging reveals an acid pH-dependent conformational switch in SsrB regulates SPI-2
Q39503194SirA orthologs affect both motility and virulence
Q48068476SlyA, a regulatory protein from Salmonella typhimurium, induces a haemolytic and pore-forming protein in Escherichia coli.
Q35451012Spacious phagosome formation within mouse macrophages correlates with Salmonella serotype pathogenicity and host susceptibility
Q40329871SprB is the molecular link between Salmonella pathogenicity island 1 (SPI1) and SPI4.
Q93128483Synergistic action of SPI-1 gene expression in Salmonella enterica serovar typhimurium through transcriptional crosstalk with the flagellar system
Q35549256Synergistic effect of mutations in invA and lpfC on the ability of Salmonella typhimurium to cause murine typhoid.
Q40563799Systemic and enteric colonization of pigs by a hilA signature-tagged mutant of Salmonella choleraesuis
Q34982986Tetracycline accelerates the temporally-regulated invasion response in specific isolates of multidrug-resistant Salmonella enterica serovar Typhimurium
Q39571299The Chromobacterium violaceum type III effector CopE, a guanine nucleotide exchange factor for Rac1 and Cdc42, is involved in bacterial invasion of epithelial cells and pathogenesis
Q38298661The HilA box and sequences outside it determine the magnitude of HilA-dependent activation of P(prgH) from Salmonella pathogenicity island 1.
Q24683356The RNA chaperone Hfq is essential for the virulence of Salmonella typhimurium
Q50129536The RcsB-RcsC regulatory system of Salmonella typhi differentially modulates the expression of invasion proteins, flagellin and Vi antigen in response to osmolarity
Q33991194The SPI-3 pathogenicity island of Salmonella enterica
Q48080387The Salmonella typhimurium invasion genes invF and invG encode homologues of the AraC and PulD family of proteins
Q38254988The Sm-like RNA chaperone Hfq mediates transcription antitermination at Rho-dependent terminators.
Q36826987The actin-polymerizing activity of SipA is not essential for Salmonella enterica serovar Typhimurium-induced mucosal inflammation
Q50119966The cis requirements for transcriptional activation by HilA, a virulence determinant encoded on SPI-1.
Q27349314The cost of virulence: retarded growth of Salmonella Typhimurium cells expressing type III secretion system 1
Q35113241The effect of cell growth phase on the regulatory cross-talk between flagellar and Spi1 virulence gene expression
Q40463256The evolution off invasion by enteric bacteria
Q42704899The fimYZ genes regulate Salmonella enterica Serovar Typhimurium invasion in addition to type 1 fimbrial expression and bacterial motility
Q34222261The flagellar regulator fliT represses Salmonella pathogenicity island 1 through flhDC and fliZ.
Q40312719The outer core lipopolysaccharide of Salmonella enterica serovar Typhi is required for bacterial entry into epithelial cells.
Q42133615The potassium transporter Trk and external potassium modulate Salmonella enterica protein secretion and virulence
Q49964101The protein acyltransferase Pat post-transcriptionally controls HilD to repress Salmonella invasion
Q40625112The putative iron transport system SitABCD encoded on SPI1 is required for full virulence of Salmonella typhimurium.
Q33649749The role of coupled positive feedback in the expression of the SPI1 type three secretion system in Salmonella
Q44518273Tolerance to stress and ability of acid-adapted and non-acid-adapted Salmonella enterica serovar Typhimurium DT104 to invade and survive in mammalian cells in vitro
Q34004705Transcriptional organization and function of invasion genes within Salmonella enterica serovar Typhimurium pathogenicity island 1, including the prgH, prgI, prgJ, prgK, orgA, orgB, and orgC genes
Q35418436Transepithelial signaling to neutrophils by salmonellae: a novel virulence mechanism for gastroenteritis.
Q41982767Two-component regulators control hilA expression by controlling fimZ and hilE expression within Salmonella enterica serovar Typhimurium.
Q24548602Type III protein secretion systems in bacterial pathogens of animals and plants
Q26860755Typhoid fever: "you can't hit what you can't see"
Q33938222Unravelling the mysteries of virulence gene regulation in Salmonella typhimurium
Q46089870Use of Transcriptional Control to Increase Secretion of Heterologous Proteins in T3S Systems
Q48266350Use of a Salmonella typhimurium hilA fusion strain to assess effects of environmental fresh water sources on virulence gene expression
Q36747136Use of gene dosage effects for a whole-genome screen to identify Mycobacterium marinum macrophage infection loci
Q34469867Use of mixed infections with Salmonella strains to study virulence genes and their interactions in vivo
Q34261257Using transcriptional control to increase titers of secreted heterologous proteins by the type III secretion system
Q41215879Virulence Gene Regulation by L-Arabinose in Salmonella enterica
Q34351885Yersinia enterocolitica invasin: a primary role in the initiation of infection
Q41112766ZBP-89 regulates expression of tryptophan hydroxylase I and mucosal defense against Salmonella typhimurium in mice.
Q40552048ppGpp-dependent stationary phase induction of genes on Salmonella pathogenicity island 1.

Search more.