scholarly article | Q13442814 |
P50 | author | Paul Greengard | Q309979 |
Richard Neubig | Q67330747 | ||
Jürgen Wess | Q90287368 | ||
Weixing Shen | Q114738724 | ||
Tim Fieblinger | Q114738725 | ||
Erwan Bezard | Q38544252 | ||
Veronica Francardo | Q56499969 | ||
Joshua L Plotkin | Q56499983 | ||
M. Angela Cenci Nilsson | Q64821172 | ||
Craig W. Lindsley | Q67215429 | ||
P. Jeffrey Conn | Q67215432 | ||
P2093 | author name string | Qin Li | |
Wai Kin D Ko | |||
Zhong Xie | |||
D James Surmeier | |||
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From reinforcement learning models to psychiatric and neurological disorders | Q34161002 | ||
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Striatal cholinergic cell ablation attenuates L-DOPA induced dyskinesia in Parkinsonian mice. | Q37597274 | ||
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Neuromodulatory control of striatal plasticity and behavior. | Q37844744 | ||
A critique of available scales and presentation of the Non-Human Primate Dyskinesia Rating Scale | Q38043416 | ||
Selectivity and anti-Parkinson's potential of thiadiazolidinone RGS4 inhibitors | Q38890700 | ||
Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists. | Q39353443 | ||
Aberrant striatal plasticity is specifically associated with dyskinesia following levodopa treatment | Q39398723 | ||
Selective loss of bi-directional synaptic plasticity in the direct and indirect striatal output pathways accompanies generation of parkinsonism and l-DOPA induced dyskinesia in mouse models | Q41584434 | ||
Ratings of L-DOPA-induced dyskinesia in the unilateral 6-OHDA lesion model of Parkinson's disease in rats and mice | Q42168324 | ||
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Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia | Q44383212 | ||
Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function | Q44436562 | ||
Plastic and behavioral abnormalities in experimental Huntington's disease: a crucial role for cholinergic interneurons | Q45299250 | ||
Muscarinic inhibition of hippocampal and striatal adenylyl cyclase is mainly due to the M(4) receptor. | Q46134759 | ||
L-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice | Q46136644 | ||
Dopamine receptor activation is required for corticostriatal spike-timing-dependent plasticity. | Q46717148 | ||
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Reversal of cocaine-evoked synaptic potentiation resets drug-induced adaptive behaviour | Q48204993 | ||
Phenotypical characterization of the rat striatal neurons expressing muscarinic receptor genes | Q48433708 | ||
Striatal dopamine release is triggered by synchronized activity in cholinergic interneurons | Q48441601 | ||
D1/D5 dopamine receptors inhibit depotentiation at CA1 synapses via cAMP-dependent mechanism. | Q48514262 | ||
RGS4 inhibits signaling by group I metabotropic glutamate receptors. | Q48539239 | ||
SK channel modulation rescues striatal plasticity and control over habit in cannabinoid tolerance | Q48720514 | ||
Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity | Q59065408 | ||
The Distinct Role of Medium Spiny Neurons and Cholinergic Interneurons in the D2/A2A Receptor Interaction in the Striatum: Implications for Parkinson's Disease | Q60715991 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | dyskinesia | Q629444 |
striatum | Q1319792 | ||
P304 | page(s) | 762-773 | |
P577 | publication date | 2015-11-01 | |
P1433 | published in | Neuron | Q3338676 |
P1476 | title | M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia | |
P478 | volume | 88 |
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Q89167851 | Aberrant Striatal Activity in Parkinsonism and Levodopa-Induced Dyskinesia |
Q90205448 | An Interhelical Salt Bridge Controls Flexibility and Inhibitor Potency for Regulators of G-protein Signaling Proteins 4, 8, and 19 |
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Q99619162 | Basal Ganglia-A Motion Perspective |
Q49361175 | Basal ganglia mechanisms in action selection, plasticity, and dystonia. |
Q48631361 | Ceftriaxone reduces L-dopa-induced dyskinesia severity in 6-hydroxydopamine parkinson's disease model. |
Q46447901 | Challenges in the development of an M4 PAM in vivo tool compound: The discovery of VU0467154 and unexpected DMPK profiles of close analogs |
Q47581410 | Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and biological characterization of a series of azetidine-derived tertiary amides. |
Q50993859 | Challenges in the development of an M4 PAM preclinical candidate: The discovery, SAR, and in vivo characterization of a series of 3-aminoazetidine-derived amides. |
Q37507773 | Cholinergic Interneurons Amplify Corticostriatal Synaptic Responses in the Q175 Model of Huntington's Disease. |
Q52740407 | Cholinergic Projections to the Substantia Nigra Pars Reticulata Inhibit Dopamine Modulation of Basal Ganglia through the M4 Muscarinic Receptor. |
Q88803206 | Cholinergic modulation of striatal microcircuits |
Q64251973 | Delayed Spine Pruning of Direct Pathway Spiny Projection Neurons in a Mouse Model of Parkinson's Disease |
Q49821000 | Differential Protein Dynamics of Regulators of G-protein Signaling: Role in Specificity of Small-molecule Inhibitors. |
Q38436762 | Discovery and SAR of a novel series of potent, CNS penetrant M4 PAMs based on a non-enolizable ketone core: Challenges in disposition |
Q38437959 | Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine core |
Q47644788 | Discovery of a novel 2,4-dimethylquinoline-6-carboxamide M4 positive allosteric modulator (PAM) chemotype via scaffold hopping |
Q47864774 | Discovery of a novel, CNS penetrant M4 PAM chemotype based on a 6-fluoro-4-(piperidin-1-yl)quinoline-3-carbonitrile core |
Q89584480 | Effects of histone acetyltransferase inhibitors on L-DOPA-induced dyskinesia in a murine model of Parkinson's disease |
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Q60141509 | Inhaling xenon ameliorates l-dopa-induced dyskinesia in experimental parkinsonism |
Q54981672 | Inhibition of basal and amphetamine-stimulated extracellular signal-regulated kinase (ERK) phosphorylation in the rat forebrain by muscarinic acetylcholine M4 receptors. |
Q90304563 | Interplay of cysteine exposure and global protein dynamics in small-molecule recognition by a regulator of G-protein signaling protein |
Q42498429 | Involvement of Striatal Cholinergic Interneurons and M1 and M4 Muscarinic Receptors in Motor Symptoms of Parkinson's Disease |
Q52655473 | Kainate Receptors Inhibit Glutamate Release Via Mobilization of Endocannabinoids in Striatal Direct Pathway Spiny Projection Neurons. |
Q48113066 | Levodopa treatment and dendritic spine pathology |
Q37516434 | Maladaptive Synaptic Plasticity in L-DOPA-Induced Dyskinesia |
Q48177380 | Metformin Inhibits the Development of L-DOPA-Induced Dyskinesia in a Murine Model of Parkinson's Disease. |
Q38820286 | Optimization of M4 positive allosteric modulators (PAMs): The discovery of VU0476406, a non-human primate in vivo tool compound for translational pharmacology |
Q64779296 | Optogenetic Stimulation of the M2 Cortex Reverts Motor Dysfunction in a Mouse Model of Parkinson's Disease |
Q64911660 | Parkinson's Disease-Linked LRRK2-G2019S Mutation Alters Synaptic Plasticity and Promotes Resilience to Chronic Social Stress in Young Adulthood. |
Q54936284 | Pauses in cholinergic interneuron firing exert an inhibitory control on striatal output in vivo. |
Q43076051 | Physiological roles of CNS muscarinic receptors gained from knockout mice. |
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Q64901815 | Receptor Ligands as Helping Hands to L-DOPA in the Treatment of Parkinson's Disease. |
Q47909580 | Regulation of Striatal Neuron Activity by Cyclic Nucleotide Signaling and Phosphodiesterase Inhibition: Implications for the Treatment of Parkinson's Disease. |
Q39190510 | Roles of centromedian parafascicular nuclei of thalamus and cholinergic interneurons in the dorsal striatum in associative learning of environmental events |
Q64759887 | Roles of the M4 acetylcholine receptor in the basal ganglia and the treatment of movement disorders |
Q33559375 | Spine Enlargement of Pyramidal Tract-Type Neurons in the Motor Cortex of a Rat Model of Levodopa-Induced Dyskinesia |
Q64086843 | Spiny Projection Neuron Dynamics in Toxin and Transgenic Models of Parkinson's Disease |
Q42330741 | Spontaneous Synaptic Activation of Muscarinic Receptors by Striatal Cholinergic Neuron Firing |
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Q46145089 | Striatal cholinergic interneurons and D2 receptor-expressing GABAergic medium spiny neurons regulate tardive dyskinesia |
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Q89948582 | Synaptic and cellular plasticity in Parkinson's disease |
Q39381131 | Synaptic functions of endocannabinoid signaling in health and disease |
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Q89701501 | The Dopamine D5 receptor contributes to activation of cholinergic interneurons during L-DOPA induced dyskinesia |
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