M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia

scientific article published on November 2015

M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.NEURON.2015.10.039
P932PMC publication ID4864040
P698PubMed publication ID26590347
P5875ResearchGate publication ID284234423

P50authorPaul GreengardQ309979
Richard NeubigQ67330747
Jürgen WessQ90287368
Weixing ShenQ114738724
Tim FieblingerQ114738725
Erwan BezardQ38544252
Veronica FrancardoQ56499969
Joshua L PlotkinQ56499983
M. Angela Cenci NilssonQ64821172
Craig W. LindsleyQ67215429
P. Jeffrey ConnQ67215432
P2093author name stringQin Li
Wai Kin D Ko
Zhong Xie
D James Surmeier
P2860cites workCNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injuryQ73503153
A subpopulation of neuronal M4 muscarinic acetylcholine receptors plays a critical role in modulating dopamine-dependent behaviorsQ24645678
Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced hyperlocomotor activity in ratsQ24652668
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RGS4 is required for dopaminergic control of striatal LTD and susceptibility to parkinsonian motor deficitsQ30504550
Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesiaQ30650489
Dopamine dysregulation of movement control in L-DOPA-induced dyskinesiaQ33280726
An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmissionQ33308569
Cyclic AMP and afferent activity govern bidirectional synaptic plasticity in striatopallidal neuronsQ33575226
Impact of the lesion procedure on the profiles of motor impairment and molecular responsiveness to L-DOPA in the 6-hydroxydopamine mouse model of Parkinson's disease.Q33817654
From reinforcement learning models to psychiatric and neurological disordersQ34161002
Muscarinic and nicotinic cholinergic mechanisms in the mesostriatal dopamine systemsQ34176570
M4 mAChR-mediated modulation of glutamatergic transmission at corticostriatal synapsesQ34404258
Dopaminergic control of corticostriatal long-term synaptic depression in medium spiny neurons is mediated by cholinergic interneurons.Q34521936
Remote control of neuronal signalingQ34858531
L-DOPA-Induced Dyskinesia and Abnormal Signaling in Striatal Medium Spiny Neurons: Focus on Dopamine D1 Receptor-Mediated TransmissionQ35424424
Neural mechanisms of reward-related motor learningQ35602987
Mitogen-activated protein kinases in synaptic plasticity and memory.Q35803116
Modulation of striatal projection systems by dopamineQ36367283
Dopamine-mediated regulation of corticostriatal synaptic plasticity.Q36762821
Molecular mechanisms of L-DOPA-induced dyskinesiaQ37247578
Cholinergic modulation of multivesicular release regulates striatal synaptic potency and integrationQ37323686
Phosphorylation of Ser1166 on GluN2B by PKA is critical to synaptic NMDA receptor function and Ca2+ signaling in spinesQ37479508
Striatal cholinergic cell ablation attenuates L-DOPA induced dyskinesia in Parkinsonian mice.Q37597274
Neurotransmitter roles in synaptic modulation, plasticity and learning in the dorsal striatumQ37680104
Neuromodulatory control of striatal plasticity and behavior.Q37844744
A critique of available scales and presentation of the Non-Human Primate Dyskinesia Rating ScaleQ38043416
Selectivity and anti-Parkinson's potential of thiadiazolidinone RGS4 inhibitorsQ38890700
Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists.Q39353443
Aberrant striatal plasticity is specifically associated with dyskinesia following levodopa treatmentQ39398723
Selective loss of bi-directional synaptic plasticity in the direct and indirect striatal output pathways accompanies generation of parkinsonism and l-DOPA induced dyskinesia in mouse modelsQ41584434
Ratings of L-DOPA-induced dyskinesia in the unilateral 6-OHDA lesion model of Parkinson's disease in rats and miceQ42168324
Derangement of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and extracellular signal-regulated kinase (ERK) dependent striatal plasticity in L-DOPA-induced dyskinesia.Q42459246
Input- and cell-type-specific endocannabinoid-dependent LTD in the striatum.Q42470816
Distinct coincidence detectors govern the corticostriatal spike timing-dependent plasticity.Q42473820
Synaptic integration mediated by striatal cholinergic interneurons in basal ganglia functionQ42491215
A Ca(2+) threshold for induction of spike-timing-dependent depression in the mouse striatum.Q42494007
Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease modelsQ42508054
Combined fenobam and amantadine treatment promotes robust antidyskinetic effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned primate model of Parkinson's diseaseQ44050418
Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesiaQ44383212
Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor functionQ44436562
Plastic and behavioral abnormalities in experimental Huntington's disease: a crucial role for cholinergic interneuronsQ45299250
Muscarinic inhibition of hippocampal and striatal adenylyl cyclase is mainly due to the M(4) receptor.Q46134759
L-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian miceQ46136644
Dopamine receptor activation is required for corticostriatal spike-timing-dependent plasticity.Q46717148
Cholinergic modulation of Kir2 channels selectively elevates dendritic excitability in striatopallidal neurons.Q46973834
Reversal of cocaine-evoked synaptic potentiation resets drug-induced adaptive behaviourQ48204993
Phenotypical characterization of the rat striatal neurons expressing muscarinic receptor genesQ48433708
Striatal dopamine release is triggered by synchronized activity in cholinergic interneuronsQ48441601
D1/D5 dopamine receptors inhibit depotentiation at CA1 synapses via cAMP-dependent mechanism.Q48514262
RGS4 inhibits signaling by group I metabotropic glutamate receptors.Q48539239
SK channel modulation rescues striatal plasticity and control over habit in cannabinoid toleranceQ48720514
Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticityQ59065408
The Distinct Role of Medium Spiny Neurons and Cholinergic Interneurons in the D2/A2A Receptor Interaction in the Striatum: Implications for Parkinson's DiseaseQ60715991
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectdyskinesiaQ629444
striatumQ1319792
P304page(s)762-773
P577publication date2015-11-01
P1433published inNeuronQ3338676
P1476titleM4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia
P478volume88

Reverse relations

cites work (P2860)
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