Maladaptive Synaptic Plasticity in L-DOPA-Induced Dyskinesia

scientific article published on 20 December 2016

Maladaptive Synaptic Plasticity in L-DOPA-Induced Dyskinesia is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3389/FNCIR.2016.00105
P932PMC publication ID5168436
P698PubMed publication ID28066191

P50authorQiang WangQ96177284
P2093author name stringWangming Zhang
P2860cites workSignaling in dendritic spines and spine microdomainsQ26828892
The thalamostriatal system in normal and diseased statesQ26996624
Levodopa-induced plasticity: a double-edged sword in Parkinson's disease?Q27002626
Adenosine 2A receptor availability in dyskinetic and nondyskinetic patients with Parkinson diseaseQ29346490
Dichotomous dopaminergic control of striatal synaptic plasticityQ30493521
RGS4 is required for dopaminergic control of striatal LTD and susceptibility to parkinsonian motor deficitsQ30504550
Concurrent activation of striatal direct and indirect pathways during action initiation.Q30579307
Spatiotemporal pattern of striatal ERK1/2 phosphorylation in a rat model of L-DOPA-induced dyskinesia and the role of dopamine D1 receptors.Q30594829
Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesiaQ30650489
Distinct changes in cAMP and extracellular signal-regulated protein kinase signalling in L-DOPA-induced dyskinesiaQ30988635
Post- versus presynaptic plasticity in L-DOPA-induced dyskinesiaQ33255884
Enhanced striatal cholinergic neuronal activity mediates L-DOPA-induced dyskinesia in parkinsonian miceQ34490801
A Role for Mitogen- and Stress-Activated Kinase 1 in L-DOPA-Induced Dyskinesia and ∆FosB ExpressionQ35024117
Basal Ganglia disorders associated with imbalances in the striatal striosome and matrix compartmentsQ35208420
Zooming in on the small: the plasticity of striatal dendritic spines in L-DOPA-induced dyskinesiaQ35574934
Cerebellar processing of sensory inputs primes motor cortex plasticityQ36516121
Pathway-Specific Remodeling of Thalamostriatal Synapses in Parkinsonian MiceQ36599026
Dopamine-mediated regulation of corticostriatal synaptic plasticity.Q36762821
M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced DyskinesiaQ36892615
Aberrant restoration of spines and their synapses in L-DOPA-induced dyskinesia: involvement of corticostriatal but not thalamostriatal synapsesQ37048087
Role of receptor heterodimers in the development of L-dopa-induced dyskinesias in the 6-hydroxydopamine rat model of Parkinson's diseaseQ37220785
Phosphorylation of Ser1166 on GluN2B by PKA is critical to synaptic NMDA receptor function and Ca2+ signaling in spinesQ37479508
Chronic dopaminergic stimulation in Parkinson's disease: from dyskinesias to impulse control disorders.Q37631957
Levodopa-induced dyskinesias in patients with Parkinson's disease: filling the bench-to-bedside gap.Q37794467
Current options and future possibilities for the treatment of dyskinesia and motor fluctuations in Parkinson's diseaseQ37916641
New pharmacological avenues for the treatment of L-DOPA-induced dyskinesias in Parkinson's disease: targeting glutamate and adenosine receptorsQ37974709
Electrical compartmentalization in dendritic spinesQ38110905
Dopaminergic modulation of striatal networks in health and Parkinson's diseaseQ38233462
Aberrant striatal plasticity is specifically associated with dyskinesia following levodopa treatmentQ39398723
Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia.Q39426286
Substance P Weights Striatal Dopamine Transmission Differently within the Striosome-Matrix AxisQ40825163
Dopamine dynamics and cocaine sensitivity differ between striosome and matrix compartments of the striatum.Q41110130
Selective expression of one Ca(2+)-inhibitable adenylyl cyclase in dopaminergically innervated rat brain regionsQ41484982
Selective loss of bi-directional synaptic plasticity in the direct and indirect striatal output pathways accompanies generation of parkinsonism and l-DOPA induced dyskinesia in mouse modelsQ41584434
L-DOPA treatment selectively restores spine density in dopamine receptor D2-expressing projection neurons in dyskinetic mice.Q42440010
Morphological and electrophysiological changes in intratelencephalic-type pyramidal neurons in the motor cortex of a rat model of levodopa-induced dyskinesiaQ42452008
Derangement of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and extracellular signal-regulated kinase (ERK) dependent striatal plasticity in L-DOPA-induced dyskinesia.Q42459246
Lack of depotentiation at basal ganglia output neurons in PD patients with levodopa-induced dyskinesiaQ42463817
Maladaptive plasticity of serotonin axon terminals in levodopa-induced dyskinesia.Q42477740
Higher free D-aspartate and N-methyl-D-aspartate levels prevent striatal depotentiation and anticipate L-DOPA-induced dyskinesia.Q42494976
Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease modelsQ42508054
Cerebellar sensory processing alterations impact motor cortical plasticity in Parkinson's disease: clues from dyskinetic patientsQ42712278
Distinct levels of dopamine denervation differentially alter striatal synaptic plasticity and NMDA receptor subunit composition.Q42852538
Striatal inhibition of PKA prevents levodopa-induced behavioural and molecular changes in the hemiparkinsonian rat.Q43198758
Modification of adenosine extracellular levels and adenosine A(2A) receptor mRNA by dopamine denervation.Q44050773
Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesiaQ44383212
Increased adenosine A2A receptors in the brain of Parkinson's disease patients with dyskinesiasQ44807332
Persistent increase in olfactory type G-protein alpha subunit levels may underlie D1 receptor functional hypersensitivity in Parkinson disease.Q45007596
L-DOPA disrupts adenosine A(2A)-cannabinoid CB(1)-dopamine D(2) receptor heteromer cross-talk in the striatum of hemiparkinsonian rats: biochemical and behavioral studiesQ45228276
Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia.Q45923687
Genetic inactivation of dopamine D1 but not D2 receptors inhibits L-DOPA-induced dyskinesia and histone activation.Q45972521
Levodopa enhances synaptic plasticity in the substantia nigra pars reticulata of Parkinson's disease patientsQ46218711
Sprouting of dopamine terminals and altered dopamine release and uptake in Parkinsonian dyskinaesia.Q46589894
ERK phosphorylation and FosB expression are associated with L-DOPA-induced dyskinesia in hemiparkinsonian miceQ46684571
Loss of synaptic D1 dopamine/N-methyl-D-aspartate glutamate receptor complexes in L-DOPA-induced dyskinesia in the rat.Q46859525
Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models.Q46896175
l-DOPA dosage is critically involved in dyskinesia via loss of synaptic depotentiationQ46904268
Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesiaQ48124096
Cloning and expression of an adenylyl cyclase localized to the corpus striatumQ48332642
RGS4-dependent attenuation of M4 autoreceptor function in striatal cholinergic interneurons following dopamine depletionQ48540394
Gα(olf) mutation allows parsing the role of cAMP-dependent and extracellular signal-regulated kinase-dependent signaling in L-3,4-dihydroxyphenylalanine-induced dyskinesia.Q48545028
Inhibition of adenylyl cyclase type 5 prevents L-DOPA-induced dyskinesia in an animal model of Parkinson's disease.Q48579768
Abnormal bidirectional plasticity-like effects in Parkinson's diseaseQ48829642
L-DOPA-treatment in primates disrupts the expression of A(2A) adenosine-CB(1) cannabinoid-D(2) dopamine receptor heteromers in the caudate nucleusQ48873583
Parkinson's Disease: A Thalamostriatal Rebalancing Act?Q48895295
Modulation of serotonergic transmission by eltoprazine in L-DOPA-induced dyskinesia: Behavioral, molecular, and synaptic mechanisms.Q50545965
Nociceptin/Orphanin FQ Receptor Agonists Attenuate L-DOPA-Induced DyskinesiasQ57951136
The Distinct Role of Medium Spiny Neurons and Cholinergic Interneurons in the D2/A2A Receptor Interaction in the Striatum: Implications for Parkinson's DiseaseQ60715991
Atrophy of medium spiny I striatal dendrites in advanced Parkinson's diseaseQ68502274
Cortical and nigral deafferentation and striatal cholinergic markers in the rat dorsal striatum: different effects on the expression of mRNAs encoding choline acetyltransferase and muscarinic m1 and m4 receptorsQ73189222
Morphologic changes of dendritic spines of striatal neurons in the levodopa-induced dyskinesia modelQ87366704
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectamino acidQ8066
nervous systemQ9404
amineQ167198
dopamineQ170304
hydrocarbonQ43648
phenolQ407142
basal gangliaQ464210
dyskinesiaQ629444
neuroplasticityQ849491
synaptic plasticityQ1551556
P304page(s)105
P577publication date2016-12-20
P1433published inFrontiers in neural circuitsQ27721914
P1476titleMaladaptive Synaptic Plasticity in L-DOPA-Induced Dyskinesia
P478volume10

Reverse relations

cites work (P2860)
Q38618921Granger causality supports abnormal functional connectivity of beta oscillations in the dorsolateral striatum and substantia nigra pars reticulata in hemiparkinsonian rats
Q39324877Investigational drugs in Phase I and Phase II for Levodopa-induced dyskinesias
Q91637575Levodopa/Benserazide PLGA Microsphere Prevents L-Dopa-Induced Dyskinesia via Lower β-Arrestin2 in 6-Hydroxydopamine Parkinson's Rats
Q52371217Synaptic plasticity and levodopa-induced dyskinesia: electrophysiological and structural abnormalities.