Cancer karyotypes: survival of the fittest

scientific article published on 7 June 2013

Cancer karyotypes: survival of the fittest is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3389/FONC.2013.00148
P932PMC publication ID3675379
P698PubMed publication ID23760367
P5875ResearchGate publication ID237816777

P2093author name stringDaniela Cimini
Joshua M Nicholson
P2860cites workarrayMap: a reference resource for genomic copy number imbalances in human malignanciesQ21134582
Characterization of MAD2B and other mitotic spindle checkpoint genesQ22009979
The human spindle assembly checkpoint protein Bub3 is required for the establishment of efficient kinetochore-microtubule attachmentsQ24306626
Mutations of mitotic checkpoint genes in human cancersQ24320018
Genome stability is ensured by temporal control of kinetochore-microtubule dynamicsQ24322655
Aneuploid neurons are functionally active and integrated into brain circuitryQ24523693
Genetic instability of cancer cells is proportional to their degree of aneuploidyQ24653805
Aneuploidy: cells losing their balanceQ24654413
Annual cycles in the incidence of b chromosomes in the grasshopper Myrmeleotettix maculatus (acrididae: orthoptera)Q44800077
Deletion of chromosome 17p loci in breast cancer cells detected by fluorescence in situ hybridizationQ45844976
An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1.Q46684704
Sporadic aneuploidy in PHA-stimulated lymphocytes of Turner's syndrome patientsQ47843673
Mutational inactivation of mitotic checkpoint genes, hsMAD2 and hBUB1, is rare in sporadic digestive tract cancers.Q52536820
Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability.Q53639627
Genetic characterization of hyperresistance to formaldehyde and 4-nitroquinoline-N-oxide in the yeast Saccharomyces cerevisiae.Q54389654
Molecular analysis of the mitotic checkpoint genes BUB1, BUBR1 and BUB3 in human lung cancers.Q55034501
Segregation of sex chromosomes in human lymphocytesQ57961770
Stress mixes chromosomesQ58319876
Clonal karyotypic abnormalities in colorectal adenomas: Clues to the early genetic events in the adenoma‐carcinoma sequenceQ71646564
Karyotypic characterization of colorectal adenocarcinomasQ71683711
17p allelic losses in diploid cells of patients with Barrett's esophagus who develop aneuploidyQ72373931
Direct and indirect non-disjunction in the origin of trisomy in cultured human lymphocytesQ73195108
Chromosomes in cancer tissueQ74007711
Cytogenetic findings in invasive breast carcinomas with prognostically favourable histology: a less complex karyotypic pattern?Q77072079
Asynchronous replication of alleles in genomes carrying an extra autosomeQ77299868
Asynchronous replication of allelic loci in Down syndromeQ77439703
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The B chromosome databaseQ80414373
Aneuploidy as a counter to "Muller's ratchet" in cancer cellsQ81482750
Sporadic aneuploidy in PHA-stimulated lymphocytes of trisomies 21, 18, and 13Q83254170
B-chromosome evolutionQ24676371
Mad2 overexpression promotes aneuploidy and tumorigenesis in miceQ24684680
The consequences of chromosomal aneuploidy on the transcriptome of cancer cellsQ26995532
Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cellsQ27345177
AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to TaxolQ27824792
The spindle-assembly checkpoint in space and timeQ27860766
Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion SequencingQ27860948
Genetic instabilities in human cancersQ28131826
Aneuploid colon cancer cells have a robust spindle checkpointQ28343940
Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistanceQ28476322
The landscape of somatic copy-number alteration across human cancersQ29547648
THE RELATION OF RECOMBINATION TO MUTATIONAL ADVANCEQ29616118
A mechanism linking extra centrosomes to chromosomal instabilityQ29617923
Genetic instability in colorectal cancersQ29618711
Assessing the significance of chromosomal aberrations in cancer: methodology and application to gliomaQ30014823
Examining the link between chromosomal instability and aneuploidy in human cellsQ30481428
Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisonsQ30524222
TiGER: a database for tissue-specific gene expression and regulationQ33341488
A strategy for constructing aneuploid yeast strains by transient nondisjunction of a target chromosomeQ33481308
On the karyotypic origin and evolution of cancer cellsQ33506788
Proliferation of aneuploid human cells is limited by a p53-dependent mechanism.Q33643740
Whole chromosome instability caused by Bub1 insufficiency drives tumorigenesis through tumor suppressor gene loss of heterozygosityQ33743993
Amplification of the 20q chromosomal arm occurs early in tumorigenic transformation and may initiate cancerQ33812864
Patterns of genomic imbalances in human solid tumors (Review).Q33819800
Chromosomal instability confers intrinsic multidrug resistance.Q33833372
Delayed replication timing leads to delayed mitotic chromosome condensation and chromosomal instability of chromosome translocationsQ33949329
B chromosomes have a functional effect on female sex determination in Lake Victoria cichlid fishesQ34005305
Replication Timing Aberrations and Aneuploidy in Peripheral Blood Lymphocytes of Breast Cancer PatientsQ34041338
Specific aneusomies in Chinese hamster cells at different stages of neoplastic transformation, initiated by nitrosomethylureaQ34067466
A compendium of gene expression in normal human tissuesQ34107680
Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumorsQ34190883
Further evidence favoring the concept of the stem cell in ascites tumors of ratsQ34238668
Tumor heterogeneityQ34257678
Deviant kinetochore microtubule dynamics underlie chromosomal instability.Q37455785
How mitotic errors contribute to karyotypic diversity in cancer.Q37933890
Cancer: beyond speciationQ37933904
Transient defects of mitotic spindle geometry and chromosome segregation errors.Q38033746
Cancer cell micronucleus: an update on clinical and diagnostic applicationsQ38070708
Karyotypic changes as drivers and catalyzers of cellular evolvability: a perspective from non-pathogenic yeastsQ38081011
Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidyQ39184190
Replication stress links structural and numerical cancer chromosomal instabilityQ39187683
DNA breaks and chromosome pulverization from errors in mitosisQ39410009
Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawalQ39700353
Overexpression of Cdc20 leads to impairment of the spindle assembly checkpoint and aneuploidization in oral cancerQ40267243
Chromosomal alterations cause the high rates and wide ranges of drug resistance in cancer cellsQ40354395
Microcell-mediated chromosome transfer provides evidence that polysomy promotes structural instability in tumor cell chromosomes through asynchronous replication and breakage within late-replicating regionsQ40547249
Differences in malsegregation rates obtained by scoring ana-telophases or binucleate cellsQ40789142
Infrequent mutation of the hBUB1 and hBUBR1 genes in human lung cancerQ40876361
Mutation analysis of hBUB1 in aneuploid HNSCC and lung cancer cell linesQ40944054
Identification and chromosomal locations of a family of cytochrome P-450 genes for pisatin detoxification in the fungus Nectria haematococcaQ41185386
Regulation of Tissue-Specific Gene Expression in Microcell HybridsQ41230240
Aneuploidy underlies rapid adaptive evolution of yeast cells deprived of a conserved cytokinesis motorQ42033067
Aneuploidy and isochromosome formation in drug-resistant Candida albicansQ42113364
Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeastQ42369487
A Fungal Gene for Antibiotic Resistance on a Dispensable ("B") ChromosomeQ43542421
Merotelic kinetochore orientation versus chromosome mono-orientation in the origin of lagging chromosomes in human primary cells.Q43893437
Expression of recessive alleles by chromosomal mechanisms in retinoblastomaQ34264957
Karyotypic determinants of chromosome instability in aneuploid budding yeastQ34277108
Selfish supernumerary chromosome reveals its origin as a mosaic of host genome and organellar sequences.Q34291393
Constitutional aneuploidy in the normal human brain.Q34399858
Effects of aneuploidy on cellular physiology and cell division in haploid yeastQ34663956
Asynchronous replication, mono-allelic expression, and long range Cis-effects of ASAR6.Q34671981
Defining 'chromosomal instability'.Q34735361
Characterization of aneuploid populations with trisomy 7 and 20 derived from diploid human colonic epithelial cellsQ34763673
Stable karyotypes in epithelial cancer cell lines despite high rates of ongoing structural and numerical chromosomal instabilityQ34775052
An autosomal locus that controls chromosome-wide replication timing and mono-allelic expressionQ34994794
Recurrent chromosomal imbalances and structurally abnormal breakpoints within complex karyotypes of malignant peripheral nerve sheath tumour and malignant triton tumour: a cytogenetic and molecular cytogenetic study.Q35588092
Frequent aneuploidy among normal human hepatocytesQ35629294
Aneuploidy drives genomic instability in yeastQ35755405
Chromosomes with delayed replication timing lead to checkpoint activation, delayed recruitment of Aurora B and chromosome instability.Q35774465
Chromosome instability, chromosome transcriptome, and clonal evolution of tumor cell populationsQ35829179
Aneuploidy as a mechanism for stress-induced liver adaptation.Q36190750
Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregationQ36322979
Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cellsQ36360359
Mammalian chromosomes contain cis-acting elements that control replication timing, mitotic condensation, and stability of entire chromosomesQ36452963
Identification of aneuploidy-selective antiproliferation compoundsQ36493649
Chromosome transfer induced aneuploidy results in complex dysregulation of the cellular transcriptome in immortalized and cancer cellsQ36634493
Cancer cells preferentially lose small chromosomesQ36653066
Variation, "evolution", immortality and genetic instabilities in tumour cellsQ36717575
Immortality of cancers: a consequence of inherent karyotypic variations and selections for autonomyQ36724281
Regulation of tubulin levels and microtubule assembly in Saccharomyces cerevisiae: consequences of altered tubulin gene copy numberQ36728232
Cancer drug resistance: the central role of the karyotypeQ36771059
The genomically mosaic brain: aneuploidy and more in neural diversity and diseaseQ36799509
Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivoQ36944217
Trisomy correction in Down syndrome induced pluripotent stem cellsQ36995232
2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cellsQ37078688
Deregulation of the centrosome cycle and the origin of chromosomal instability in cancerQ37252374
The consequences of tetraploidy and aneuploidyQ37329862
Malignancy in children with trisomy 21.Q37379570
P921main subjectkaryotypeQ189967
P304page(s)148
P577publication date2013-06-07
P1433published inFrontiers in OncologyQ26839986
P1476titleCancer karyotypes: survival of the fittest
P478volume3

Reverse relations

cites work (P2860)
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Q38662334Centrosome amplification, chromosomal instability and cancer: mechanistic, clinical and therapeutic issues
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Q46016448Evolution of genetic instability in heterogeneous tumors.
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Q45034296Using Photoactivatable GFP to Study Microtubule Dynamics and Chromosome Segregation
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