review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | Dimitar B Nikolov | |
Juha-Pekka Himanen | |||
Nayanendu Saha | |||
P2860 | cites work | Structural and biophysical characterization of the EphB4*ephrinB2 protein-protein interaction and receptor specificity | Q24298026 |
Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling | Q24306299 | ||
Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4 | Q24336334 | ||
A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein | Q24596894 | ||
Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region | Q27635000 | ||
Crystal structure of an Eph receptor-ephrin complex | Q27637196 | ||
Cell signaling by receptor tyrosine kinases | Q27860474 | ||
The conformational plasticity of protein kinases | Q27860946 | ||
EphB receptors interact with NMDA receptors and regulate excitatory synapse formation | Q28141518 | ||
Regulated cleavage of a contact-mediated axon repellent | Q28144522 | ||
Protein tyrosine kinase structure and function | Q28145008 | ||
Mechanisms and functions of Eph and ephrin signalling | Q28208291 | ||
Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity | Q28241585 | ||
Coexpressed EphA receptors and ephrin-A ligands mediate opposing actions on growth cone navigation from distinct membrane domains | Q28244322 | ||
The many faces of SAM | Q28253873 | ||
Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling | Q28258431 | ||
The ephrins and Eph receptors in neural development | Q28266706 | ||
MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth | Q46543783 | ||
Modulation of EphA receptor function by coexpressed ephrinA ligands on retinal ganglion cell axons | Q48219540 | ||
Intracellular and trans-synaptic regulation of glutamatergic synaptogenesis by EphB receptors. | Q48361399 | ||
Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis | Q57675131 | ||
Crystal structure of the ephrin-B1 ectodomain: implications for receptor recognition and signaling | Q81062802 | ||
Distinct subdomains of the EphA3 receptor mediate ligand binding and receptor dimerization | Q28278017 | ||
Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans | Q28278222 | ||
A novel putative tyrosine kinase receptor encoded by the eph gene | Q28280591 | ||
Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis | Q28286738 | ||
Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands | Q28294023 | ||
Bidirectional Eph-ephrin signaling during axon guidance | Q28297294 | ||
A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases | Q28590498 | ||
EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets | Q28594018 | ||
Eph signaling: a structural view | Q28677705 | ||
Eph receptor signalling casts a wide net on cell behaviour | Q29619988 | ||
Crystal structure of the human ephrin-A5 ectodomain | Q30158008 | ||
EphB receptor-binding peptides identified by phage display enable design of an antagonist with ephrin-like affinity | Q31148681 | ||
Dissecting the EphA3/Ephrin-A5 interactions using a novel functional mutagenesis screen | Q33195738 | ||
Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3. | Q33215309 | ||
Eph receptors and ephrin ligands: embryogenesis to tumorigenesis | Q34103639 | ||
Eph receptors and ephrin ligands. essential mediators of vascular development. | Q34204669 | ||
Rac-dependent trans-endocytosis of ephrinBs regulates Eph-ephrin contact repulsion | Q34230386 | ||
Intramembrane cleavage of ephrinB3 by the human rhomboid family protease, RHBDL2. | Q34309079 | ||
Can Eph receptors stimulate the mind? | Q34502665 | ||
Release of full-length EphB2 receptors from hippocampal neurons to cocultured glial cells. | Q34580314 | ||
Matrix metalloproteinases in brain development and remodeling: synaptic functions and targets | Q34612561 | ||
Crystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C-shaped scaffold | Q34676632 | ||
Presenilin-dependent intramembrane cleavage of ephrin-B1. | Q34803510 | ||
"Eph receptor signalling; dimerisation just isn't enough". | Q36194505 | ||
Targeting protein-protein interactions for cancer therapy | Q36311496 | ||
Neural map specification by gradients | Q36370818 | ||
Repulsion or adhesion: receptors make the call | Q36576257 | ||
Paradoxes of the EphB4 receptor in cancer | Q36812751 | ||
Silencing of EphA3 through a cis interaction with ephrinA5. | Q40313686 | ||
EphA receptor tyrosine kinases interact with co-expressed ephrin-A ligands in cis. | Q40553748 | ||
Ephrin-A1 is expressed at sites of vascular development in the mouse | Q40833960 | ||
Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly | Q42168707 | ||
EphB-ephrinB bi-directional endocytosis terminates adhesion allowing contact mediated repulsion. | Q42795950 | ||
Theme and variations: juxtamembrane regulation of receptor protein kinases | Q43754463 | ||
An ephrin mimetic peptide that selectively targets the EphA2 receptor | Q44156005 | ||
Targeting the EphA4 receptor in the nervous system with biologically active peptides | Q44707568 | ||
Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity | Q46268655 | ||
Vav family GEFs link activated Ephs to endocytosis and axon guidance | Q46453264 | ||
P433 | issue | 5 | |
P304 | page(s) | 534-542 | |
P577 | publication date | 2007-10-24 | |
P1433 | published in | Current Opinion in Cell Biology | Q13505682 |
P1476 | title | Cell-cell signaling via Eph receptors and ephrins | |
P478 | volume | 19 |
Q34365035 | A Functional Henipavirus Envelope Glycoprotein Pseudotyped Lentivirus Assay System |
Q36431270 | A chemical genetic approach reveals distinct EphB signaling mechanisms during brain development |
Q35385982 | A disalicylic acid-furanyl derivative inhibits ephrin binding to a subset of Eph receptors |
Q47721941 | A novel feedback mechanism by Ephrin-B1/B2 in T-cell activation involves a concentration-dependent switch from costimulation to inhibition |
Q36170813 | A role for ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after stroke |
Q35778043 | A semisynthetic Eph receptor tyrosine kinase provides insight into ligand-induced kinase activation |
Q30431034 | ADAM13 induces cranial neural crest by cleaving class B Ephrins and regulating Wnt signaling |
Q51614412 | Activation of ephrinB-EphB receptor signalling in rat spinal cord contributes to maintenance of diabetic neuropathic pain. |
Q37635711 | Amino acid conjugates of lithocholic acid as antagonists of the EphA2 receptor. |
Q27660230 | An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly |
Q27661948 | Architecture of Eph receptor clusters |
Q35047331 | Association of EPHA2 polymorphisms and age-related cortical cataract in a Han Chinese population |
Q42600591 | Astrocytes in glaucomatous optic neuropathy |
Q49272910 | Calcium channels are involved in EphB/ephrinB reverse signaling‑induced apoptosis in a rat chronic ocular hypertension model |
Q37420009 | Claudin interactions in and out of the tight junction |
Q35783568 | Clinical relevance of Ephs and ephrins in cancer: lessons from breast, colorectal, and lung cancer profiling |
Q36396980 | Coexistence of EphB1 and EphrinB2 in Port Wine Stain Endothelial Progenitor Cells Contributes to Clinicopathological Vasculature Dilatation. |
Q33354173 | Comparative 3'UTR analysis allows identification of regulatory clusters that drive Eph/ephrin expression in cancer cell lines |
Q34199998 | Cooperativity between trans and cis interactions in cadherin-mediated junction formation |
Q27652284 | Crystal Structure and Carbohydrate Analysis of Nipah Virus Attachment Glycoprotein: a Template for Antiviral and Vaccine Design |
Q27651657 | Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor |
Q34170551 | Crystal structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations |
Q38196449 | Current approaches to fine mapping of antigen-antibody interactions. |
Q37860149 | Dancing with the dead: Eph receptors and their kinase-null partners |
Q33848124 | Design, synthesis and bioevaluation of an EphA2 receptor-based targeted delivery system. |
Q28573188 | Developmental course of EphA4 cellular and subcellular localization in the postnatal rat hippocampus |
Q50555759 | Dynamic Opposition of Clustered Proteins Stabilizes Cortical Polarity in the C. elegans Zygote. |
Q39893843 | E-cadherin directly contributes to PI3K/AKT activation by engaging the PI3K-p85 regulatory subunit to adherens junctions of ovarian carcinoma cells |
Q36544714 | EPHA4 is overexpressed but not functionally active in Sézary syndrome |
Q50287715 | EPHAs bind EFNAs |
Q50287716 | EPHBs bind EFNBs |
Q37996166 | Emerging zoonotic viruses: new lessons on receptor and entry mechanisms |
Q39699715 | Endothelial cells regulate cardiomyocyte development from embryonic stem cells |
Q38008492 | Eph and ephrins in epithelial stem cell niches and cancer. |
Q38209232 | Eph- and ephrin-dependent mechanisms in tumor and stem cell dynamics |
Q36576644 | Eph-A2 and Eph-A4 expression in human benign and malignant thyroid lesions: an immunohistochemical study |
Q37971902 | Eph-dependent cell-cell adhesion and segregation in development and cancer. |
Q39881917 | Eph-ephrin bidirectional signaling comes into the context of lymphocyte transendothelial migration |
Q24611588 | Eph/ephrin molecules--a hub for signaling and endocytosis |
Q35026768 | Eph/ephrin signaling in epithelial development and homeostasis |
Q26864082 | EphA receptor signaling--complexity and emerging themes |
Q36473607 | EphA/ephrin-A signaling is critically involved in region-specific apoptosis during early brain development |
Q37209165 | EphA2 and Src regulate equatorial cell morphogenesis during lens development |
Q46756335 | EphA2 and ephrin-A5 are not a receptor-ligand pair in the ocular lens |
Q30539320 | EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion |
Q36356025 | EphA6 promotes angiogenesis and prostate cancer metastasis and is associated with human prostate cancer progression |
Q57291218 | EphA8 is a Prognostic Factor for Oral Tongue Squamous Cell Carcinoma |
Q37190444 | EphA8 is a prognostic marker for epithelial ovarian cancer |
Q42962199 | EphB and Ephrin-B interactions mediate human mesenchymal stem cell suppression of activated T-cells. |
Q35039009 | EphB/ephrinB signaling in cell adhesion and migration |
Q39354035 | EphB4 promotes or suppresses Ras/MEK/ERK pathway in a context-dependent manner: Implications for EphB4 as a cancer target |
Q37448572 | EphB4 tyrosine kinase stimulation inhibits growth of MDA-MB-231 breast cancer cells in a dose and time dependent manner. |
Q37658786 | Ephrin expression and function in cancer. |
Q107161961 | Ephrin-A1 and the sheddase ADAM12 are upregulated in COVID-19 |
Q51014950 | Ephrin-B3 binds specifically to B lymphocytes in blood and induces migration. |
Q39833824 | Ephrin-independent regulation of cell substrate adhesion by the EphB4 receptor |
Q36211017 | EphrinA1 is released in three forms from cancer cells by matrix metalloproteases |
Q34845606 | EphrinA2 regulates clathrin mediated KSHV endocytosis in fibroblast cells by coordinating integrin-associated signaling and c-Cbl directed polyubiquitination |
Q38112820 | Ephrins and pain |
Q36445643 | Expression and activation of ephexin is altered after spinal cord injury |
Q35678362 | Extracellular complexes of the hematopoietic human and mouse CSF-1 receptor are driven by common assembly principles |
Q35585316 | Forward signaling by EphB1/EphB2 interacting with ephrin-B ligands at the optic chiasm is required to form the ipsilateral projection |
Q28943468 | Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci |
Q48250386 | GluA2 trafficking is involved in apoptosis of retinal ganglion cells induced by activation of EphB/EphrinB reverse signaling in a rat chronic ocular hypertension model. |
Q37387884 | Guidance from above: common cues direct distinct signaling outcomes in vascular and neural patterning |
Q35658146 | Hendra and nipah infection: pathology, models and potential therapies |
Q38018531 | Henipavirus receptor usage and tropism |
Q36125047 | Homotypic receptor-receptor interactions regulating Eph signaling |
Q27651214 | Host cell recognition by the henipaviruses: Crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3 |
Q47948003 | Inhibition of Notch signaling induces extensive intussusceptive neo-angiogenesis by recruitment of mononuclear cells |
Q27679723 | Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5 |
Q37596072 | Integrative mechanisms of oriented neuronal migration in the developing brain |
Q38262354 | Interaction of KSHV with host cell surface receptors and cell entry |
Q28072153 | KSHV Entry and Trafficking in Target Cells-Hijacking of Cell Signal Pathways, Actin and Membrane Dynamics |
Q35983048 | Kaposi's sarcoma-associated herpesvirus interacts with EphrinA2 receptor to amplify signaling essential for productive infection |
Q27660088 | Left-Handed Dimer of EphA2 Transmembrane Domain: Helix Packing Diversity among Receptor Tyrosine Kinases |
Q38304820 | Lipid rafts: integrated platforms for vascular organization offering therapeutic opportunities |
Q26825533 | Membrane microdomains: from seeing to understanding |
Q33854483 | Multifaceted Roles of Metzincins in CNS Physiology and Pathology: From Synaptic Plasticity and Cognition to Neurodegenerative Disorders |
Q41489837 | Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain |
Q58566558 | Non-syndromic Cleft Lip and Palate Polymorphisms Affect Normal Lip Morphology |
Q34080529 | Novel approach for coexpression analysis of E2F1-3 and MYC target genes in chronic myelogenous leukemia. |
Q34681546 | Oligomerization and nanocluster organization render specificity |
Q33599430 | Overexpression of erythropoietin-producing hepatocyte receptor B4 and ephrin-B2 is associated with estrogen receptor expression in endometrial adenocarcinoma |
Q51125382 | Overexpression of junctional adhesion molecule-A and EphB2 predicts poor survival in lung adenocarcinoma patients. |
Q34364217 | Peritumoral small ephrinA5 isoform level predicts the postoperative survival in hepatocellular carcinoma |
Q34545853 | Phase transitions of multivalent proteins can promote clustering of membrane receptors |
Q36103829 | Prognostic significance of differential expression of angiogenic genes in women with high-grade serous ovarian carcinoma |
Q91756320 | Prognostic value of ephrin B receptors in breast cancer: An online survival analysis using the microarray data of 3,554 patients |
Q34141080 | Protein dynamics at Eph receptor-ligand interfaces as revealed by crystallography, NMR and MD simulations |
Q36971305 | Quantitative Phosphoproteomics Reveals Wee1 Kinase as a Therapeutic Target in a Model of Proneural Glioblastoma. |
Q37197931 | Receptor tyrosine kinase EphA2 mediates thrombin-induced upregulation of ICAM-1 in endothelial cells in vitro |
Q48200972 | Reduction and the intracellular translocation of EphB2 in Tg2576 mice and the effects of β-amyloid |
Q38089749 | Regulation of contact inhibition of locomotion by Eph-ephrin signalling. |
Q28263026 | Should I stay or should I go? Ephs and ephrins in neuronal migration |
Q91995495 | Single-cell connectomic analysis of adult mammalian lungs |
Q41875227 | Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors |
Q27651810 | Spatial Structure and pH-dependent Conformational Diversity of Dimeric Transmembrane Domain of the Receptor Tyrosine Kinase EphA1 |
Q90744589 | Spatiomechanical Modulation of EphB4-Ephrin-B2 Signaling in Neural Stem Cell Differentiation |
Q27657815 | Structural Plasticity of Eph Receptor A4 Facilitates Cross-Class Ephrin Signaling |
Q90240356 | Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus |
Q27656995 | Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases |
Q39794718 | Structure-activity relationship study of EphB3 receptor tyrosine kinase inhibitors |
Q39072727 | Synthesis and structure-activity relationships of amino acid conjugates of cholanic acid as antagonists of the EphA2 receptor. |
Q37324256 | The ADAMs: signalling scissors in the tumour microenvironment |
Q83225221 | The Eph/ephrinB signal balance determines the pattern of T-cell maturation in the thymus |
Q36950556 | The EphA2 receptor and ephrinA1 ligand in solid tumors: function and therapeutic targeting |
Q46179229 | The EphB6 receptor is overexpressed in pediatric T cell acute lymphoblastic leukemia and increases its sensitivity to doxorubicin treatment |
Q37116352 | The Mechanism of Regulated Release of Lasso/Teneurin-2 |
Q24321690 | The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors |
Q37383066 | The etiopathogenesis of cleft lip and cleft palate: usefulness and caveats of mouse models |
Q64087426 | The first identification of complete Eph-ephrin signalling in ctenophores and sponges reveals a role for neofunctionalization in the emergence of signalling domains |
Q26998097 | The genetics and neuropathology of Alzheimer's disease |
Q38609464 | The role of Eph/ephrin molecules in stromal–hematopoietic interactions |
Q57812327 | Therapeutic potential of targeting the Eph/ephrin signaling complex |
Q37629840 | Tie2 and Eph receptor tyrosine kinase activation and signaling |
Q36901612 | Toward the semisynthesis of multidomain transmembrane receptors: modification of Eph tyrosine kinases |
Q52624517 | Transmission of Turnip yellows virus by Myzus persicae Is Reduced by Feeding Aphids on Double-Stranded RNA Targeting the Ephrin Receptor Protein. |
Q42558370 | Treatment with ephrin B2 positively impacts the abnormal metabolism of human osteoarthritic chondrocytes |
Q36509470 | Understanding cytokine and growth factor receptor activation mechanisms |
Q35943908 | Vascular endothelial growth factor A competitively inhibits platelet-derived growth factor (PDGF)-dependent activation of PDGF receptor and subsequent signaling events and cellular responses |
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